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GITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAPHVAEADARVRLPQTTDYLNAEAIIAAAQAA GADAVHPGYGFLSENAEFAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDPDAVTTAQ LPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQSAFGDPTVFCERYLPTGHHVEVQVMADTHGTVW AVGERECSIQRRHQKIIEEAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEFYF LEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPPPAQGYSIEARLYAEDPAHGWQPQAGVMHTI EVPGVRAQFDSLGQRTGIRLDSGIVDGSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARLHGLRTN RELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLSAIAAALADAEHNRASAGVFSSIPSGW RNLASGYQVKTYRDDADTEHRVEYRFTRTGLALPGDPVVQLVSADVDQVVLAQDGVAHGFTVARHGPDVY VDSARGPVHLVALSRFPEPSSAVEQGSLVAPMPGNVIRIGAEVGDTVTAGQPLIWLEAMKMEHTIAAPAD GVLTHVSVNTGQQVEVGAILARVEAPQNGPAEGDSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0973c | accA2 | - | 100% (667) | PROBABLE ACETYL-/PROPIONYL-COENZYME A CARBOXYLASE ALPHA CHAIN (ALPHA SUBUNIT) ACCA2: BIOTIN CARBOXYLASE + BIOTIN CARBOXYL CARRIER PROTEIN (BCCP) |
| M. tuberculosis H37Rv | Rv2501c | accA1 | e-124 | 42.22% (668) | acetyl-/propionyl-coenzyme A carboxylase subunit alpha |
| M. tuberculosis H37Rv | Rv3285 | accA3 | 5e-95 | 36.12% (670) | bifunctional acetyl-/propionyl-coenzyme A carboxylase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0998c | accA2 | 0.0 | 99.85% (667) | acetyl-/propionyl-coenzyme A carboxylase subunit alpha |
| M. gilvum PYR-GCK | Mflv_1882 | - | 0.0 | 70.36% (658) | pyruvate carboxylase |
| M. leprae Br4923 | MLBr_00726 | bccA | 2e-96 | 35.17% (671) | acetyl/propionyl CoA carboxylase alpha subunit |
| M. abscessus ATCC 19977 | MAB_1071c | - | 0.0 | 65.73% (677) | acetyl-/propionyl-CoA carboxylase alpha subunit AccA2 |
| M. marinum M | MMAR_4534 | accA2 | 0.0 | 84.86% (667) | acetyl-/propionyl-coenzyme A carboxylase alpha chain, AccA2 |
| M. avium 104 | MAV_1089 | - | 0.0 | 82.36% (669) | carbamoyl-phosphate synthase L subunit |
| M. smegmatis MC2 155 | MSMEG_5493 | - | 0.0 | 71.17% (659) | acetyl-/propionyl-coenzyme A carboxylase alpha chain |
| M. thermoresistible (build 8) | TH_3286 | - | 1e-134 | 43.83% (673) | PUTATIVE acetyl-/propionyl-coenzyme A carboxylase alpha chain |
| M. ulcerans Agy99 | MUL_4706 | accA2 | 0.0 | 85.01% (667) | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 |
| M. vanbaalenii PYR-1 | Mvan_4849 | - | 0.0 | 71.93% (659) | carbamoyl-phosphate synthase L chain, ATP-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0973c|M.tuberculosis_H37Rv ---------MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
Mb0998c|M.bovis_AF2122/97 ---------MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
MMAR_4534|M.marinum_M -------MPMSITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
MUL_4706|M.ulcerans_Agy99 ---------MSITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
MAV_1089|M.avium_104 ---------MGITRVLVANRGEIARRVFATCRRLGVSTVAVYTDPDAGAP
Mflv_1882|M.gilvum_PYR-GCK ----------MISRVLVANRGEIARRVFATCRRLGIGTVAVYTDPDADAP
Mvan_4849|M.vanbaalenii_PYR-1 ----------MITRVLVANRGEIARRVFATCRRLGIGTVAVYTDADAGAP
MSMEG_5493|M.smegmatis_MC2_155 ----------MITRVLVANRCEIARRVFATCRRLGIGTVAVYTDPDADLP
MAB_1071c|M.abscessus_ATCC_199 MTRKESMTVPSITSVLVANRGEIARRVFATCRKLGLGTVAVYSDADADSP
TH_3286|M.thermoresistible__bu --------------VLVANRGEIAVRVMSTLRRMGIRSVAVFSDADAQAR
MLBr_00726|M.leprae_Br4923 ---MASHASSRIAKVLVANRGEIAVRVIRAARDARLPSVAVYAEPDAEAP
****** *** **: : * : :***:::.**
Rv0973c|M.tuberculosis_H37Rv HVAEADARVRLPQTT---DYLNAEAIIAAAQAAGADAVHPGYGFLSENAE
Mb0998c|M.bovis_AF2122/97 HVAEADARVRLPQTT---DYLNAEAIIAAAQAAGADAVHPGYGFLSENAE
MMAR_4534|M.marinum_M HVAESDARVRLAQTN---DYLNAEAIIAAARAAGADAIHPGYGFLSENPE
MUL_4706|M.ulcerans_Agy99 HVAESDARVRLAQTN---DYLNAEAIIAAARAAGADAIHPGYGFLSENPE
MAV_1089|M.avium_104 HVAEADARVRLPNTT---DYLNIEAIIGAARAAGADALHPGYGFLSENAD
Mflv_1882|M.gilvum_PYR-GCK HVAEADARVRLEGTR---GYLDPTQLVAAALASGADAIHPGYGFLSEKPD
Mvan_4849|M.vanbaalenii_PYR-1 HVAEADARVRLTGTR---GYLDAAQLIAAARSSGADAIHPGYGFLSENPD
MSMEG_5493|M.smegmatis_MC2_155 HVAEADARVRLQGRN---GYLDIAQIIAAAQASGADAIHPGYGFLSENPD
MAB_1071c|M.abscessus_ATCC_199 HVSEADAAVHLPGTSSAETYLRGELIIAAAKATGADAIHPGYGFLSENAD
TH_3286|M.thermoresistible__bu HVAEADAAVHIGPAAARHSYLDIEAVVRAARRTGAQAVHPGYGFLSENPE
MLBr_00726|M.leprae_Br4923 HVRLADEAFALGGHTSAESYLDFGKILDAAAKSGANAIHPGYGFLAENAD
** :* . : ** :: ** :**:*:*******:*:.:
Rv0973c|M.tuberculosis_H37Rv FAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDP----
Mb0998c|M.bovis_AF2122/97 FAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDP----
MMAR_4534|M.marinum_M FAAAVTAAGLTWIGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP----
MUL_4706|M.ulcerans_Agy99 FAAAVTAAGLTWIGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP----
MAV_1089|M.avium_104 FATAVADAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP----
Mflv_1882|M.gilvum_PYR-GCK FAAAVQGAELTWIGPPVAAVAAMGSKIEAKKMMAAAGVPVLDELDP----
Mvan_4849|M.vanbaalenii_PYR-1 FAAAVQDAGLRWIGPPVAAVAAMGSKIEAKKLMAAAGVPVLDELDP----
MSMEG_5493|M.smegmatis_MC2_155 FAAAVIDAGLTWIGPPVAAVSAMGSKIEAKKLMAAAGVPVLTELDP----
MAB_1071c|M.abscessus_ATCC_199 FARAVADAGLTWIGPPVAAIESMGSKIESKKLMDAAGVPVLGQLDP----
TH_3286|M.thermoresistible__bu FAAALADAGIVFIGPPAAAIRTMGDKIAARAAVSAFGVPVVPGISRPGLT
MLBr_00726|M.leprae_Br4923 FAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPGTPDPVKN
** *: * : ::**. :: :*.*: :: .*::
Rv0973c|M.tuberculosis_H37Rv -----DAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQS
Mb0998c|M.bovis_AF2122/97 -----DAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQS
MMAR_4534|M.marinum_M -----ETVTATQLPVLVKASAGGGGRGMRVVRELSALPAEVEAARREAQS
MUL_4706|M.ulcerans_Agy99 -----ETVTAAQLPVLVKASAGGGGRGMRVVRELSALPAEVEAARREAQS
MAV_1089|M.avium_104 -----DTVTEAQLPVLVKASAGGGGRGMRVVHELSALRGEVEAARREAQS
Mflv_1882|M.gilvum_PYR-GCK -----DAVTAAMLPVLIKASAGGGGRGMRIVRELAELPIQVAAARREAQS
Mvan_4849|M.vanbaalenii_PYR-1 -----DTVTADMLPVLVKASAGGGGRGMRVVRDLAELPAQVEAARREAQS
MSMEG_5493|M.smegmatis_MC2_155 -----DTVTAEQLPVLVKASAGGGGRGMRVVGDLAALPDEVAAAQREAQS
MAB_1071c|M.abscessus_ATCC_199 -----ETVTTAQLPVLVKASAGGGGRGMRIVSELDKLPAEIAAAQREAQS
TH_3286|M.thermoresistible__bu DADLIDGAAQVGFPVLVKPSAGGGGKGMRVVHDPADLPAALAAARREAAA
MLBr_00726|M.leprae_Br4923 ADEVVAFAKEHGVPIAIKAAFGGGGKGMKVARTLEEISELYESAVREATV
. .*: :*.: ****:**::. : :* ***
Rv0973c|M.tuberculosis_H37Rv AFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSIQRRHQKIIE
Mb0998c|M.bovis_AF2122/97 AFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSFQRRHQKIIE
MMAR_4534|M.marinum_M AFGDPTVFCERYLPTGHHIEVQVMADTHGTVWAVGERECSIQRRHQKIIE
MUL_4706|M.ulcerans_Agy99 AFGDPTVFCERYLPTGHHIEVQVMADTHGTVWAVGERECSIQRRHQKIIE
MAV_1089|M.avium_104 AFGDPTVFCERYLPTGHHVEVQVLADAHGTVWAVGERECSIQRRHQKIIE
Mflv_1882|M.gilvum_PYR-GCK AFGDPTVFCERYLDAGHHVEVQVMADAHGTVWALGERECSIQRRHQKIIE
Mvan_4849|M.vanbaalenii_PYR-1 AFGDPTVFCERYLDAGHHVEVQVMADVHGTVWAVGERECSIQRRHQKIIE
MSMEG_5493|M.smegmatis_MC2_155 AFGDPTVFCEHYLAAGHHVEVQVLADAHGTVWTVGERECSIQRRHQKVIE
MAB_1071c|M.abscessus_ATCC_199 AFGDPTVFCERYLGTGRHIEVQVMADAHGTVWAVGERECSIQRRHQKVIE
TH_3286|M.thermoresistible__bu AFGDDTLFLERFVLNPRHIEVQVLADQHGNVIHLGERECSLQRRHQKVIE
MLBr_00726|M.leprae_Br4923 AFGRGECFVERYLDKPRHVEAQVIADQHGNIVVAGTRDCSLQRRFQKLVE
*** * *::: :*:*.**:** **.: * *:**:***.**::*
Rv0973c|M.tuberculosis_H37Rv EAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEF
Mb0998c|M.bovis_AF2122/97 EAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEF
MMAR_4534|M.marinum_M EAPSPLVQRIPGMRAKLFDAARLAAEAIGYTGAGTVEFLADDA----GEF
MUL_4706|M.ulcerans_Agy99 EAPSPLVQRIPGMRAKLFDAARLAAEAIGYTGAGTVEFLADDA----GEF
MAV_1089|M.avium_104 EAPSPLVERTPGMRAKLFEAARLAAGVIGYTGAGTVEFLADDD----GEF
Mflv_1882|M.gilvum_PYR-GCK EAPSPLVERTPGMRERLFDAARLAAEAIGYTGAGTVEFMASGQGEPGGSF
Mvan_4849|M.vanbaalenii_PYR-1 EAPSPLVERVAGMRDKLFEAARLAATAIGYSGAGTVEFMADDQG----AF
MSMEG_5493|M.smegmatis_MC2_155 EAPSPLVERTPGMRAKLFDAARLAAQAIGYTGAGTVEFMADDNG----DF
MAB_1071c|M.abscessus_ATCC_199 EAPSPLVTRIDGMRERLFQASRTAAAAIGYVGAGTMEFLATEDG----EF
TH_3286|M.thermoresistible__bu EAPSPLLDAAT--RERIGSAACDTARSVDYTGAGTVEFIVSADR--PDEF
MLBr_00726|M.leprae_Br4923 EAPAPFLTDAQ--RKEIHESAKRICKEAHYYGAGTVEYLVGQDG----LI
***:*:: * .: .:: . * ****:*::. :
Rv0973c|M.tuberculosis_H37Rv YFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPP--PAQGYS
Mb0998c|M.bovis_AF2122/97 YFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPP--PAQGYS
MMAR_4534|M.marinum_M YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGGRLQAEPP--PAHGHS
MUL_4706|M.ulcerans_Agy99 YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGGRLLAEPP--PAHGHS
MAV_1089|M.avium_104 YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGARLDAEPP--AAQGYS
Mflv_1882|M.gilvum_PYR-GCK YFLEMNTRLQVEHPVTELTAGLDLVELQIAVADGAPLDPAPP--TPRGAA
Mvan_4849|M.vanbaalenii_PYR-1 FFLEMNTRLQVEHPVTELTSGVDLVELQLAVADGATLDPSPP--APRGAS
MSMEG_5493|M.smegmatis_MC2_155 FFLEMNTRLQVEHPVTEATTGLDLVELQLLVADGGRLDPEPP--PTRGAA
MAB_1071c|M.abscessus_ATCC_199 FFLEMNTRLQVEHPVTECTTGLDLVALQIQVADGGTLPAEPP--AIQGHS
TH_3286|M.thermoresistible__bu FFMEMNTRLQVEHPVTEMVTGVDLVEQQIRIAAGEKLAIAQDDVTLSGHA
MLBr_00726|M.leprae_Br4923 SFLEVNTRLQVEHPVTEETTGIDLVLQQFKIANGEKLELIKDP-IPCGHA
*:*:************ .:*:*** *: :* * * :
Rv0973c|M.tuberculosis_H37Rv IEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQ--RTGIRLDSGI
Mb0998c|M.bovis_AF2122/97 IEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQ--RTGIRLDSGI
MMAR_4534|M.marinum_M IEARLYAEDPAQGWQPQAGAMHTIEVPSVRAEFATLGQ--RTGIRLDSGI
MUL_4706|M.ulcerans_Agy99 IEARLYAEDPAQGWQPQAGAMHTIEVPSVRAEFATLGQ--RTGIRLDSGI
MAV_1089|M.avium_104 IEARLYAEDPARGWQPQAGVVHAFAVPSVRAEFGSLGR--RIGIRLDAGI
Mflv_1882|M.gilvum_PYR-GCK IEARLYAEDPARNWQPQAGTVAHFDVPTAACEFGLL-E--RAGVRVDSGV
Mvan_4849|M.vanbaalenii_PYR-1 IEARLYAEDPANNWQPQPGAVHHFDVPTAGVEFGPL-D--RTGVRLDSGI
MSMEG_5493|M.smegmatis_MC2_155 IEARIYAEDPAKDWQPQAGTLHRFDFPEN--------------VRTDTGF
MAB_1071c|M.abscessus_ATCC_199 IEARLYAENPAAGWQPQSGTVRRFDIPGATAEFHLPGHPGRNGVRLDSMI
TH_3286|M.thermoresistible__bu VEARIYAEDPAAGFLPTGGTVLHVAEPDHP------------GVRVDSGL
MLBr_00726|M.leprae_Br4923 IEFRINGEDAGRNFLPSPGPVSKFHPPTGP------------GVRLDSGV
:* *: .*:.. .: * * : . * :* *: .
Rv0973c|M.tuberculosis_H37Rv VD----------GSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARL
Mb0998c|M.bovis_AF2122/97 VD----------GSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARL
MMAR_4534|M.marinum_M VD----------GSVVSIHYDPMLAKVISYAPTRRQSALVLADALARAHL
MUL_4706|M.ulcerans_Agy99 VD----------GSVVSIHYDPMLAKVISYAPTRRQSALVLADALARAHL
MAV_1089|M.avium_104 TD----------GFAVSIHYDPMLAKVISYAPTRRQAALVLADALTRTRV
Mflv_1882|M.gilvum_PYR-GCK TD----------GSVISVFYDPMIAKVISYAPSRPQAAALLADALTRTRL
Mvan_4849|M.vanbaalenii_PYR-1 TD----------GAVISVFYDPMIAKVISYAPTRRQAAALLADALTRARI
MSMEG_5493|M.smegmatis_MC2_155 VD----------GSVVSVFYDSMLAKVIAHAPTRRRAAAVLADALARARI
MAB_1071c|M.abscessus_ATCC_199 ETGAEVEGRPLRGSTVSVHYDPMLAKVITVAPTRTEAARLLASTLERARI
TH_3286|M.thermoresistible__bu FD----------GTVVGSDYDPMLAKVIAHGPDRATALRTLDRALADTAI
MLBr_00726|M.leprae_Br4923 ET----------GSVIGGQFDSMLAKLIVHGATRQEALARARRALDEFEV
* .:. :*.*:**:: .. * : :* :
Rv0973c|M.tuberculosis_H37Rv HGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLS
Mb0998c|M.bovis_AF2122/97 HGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLS
MMAR_4534|M.marinum_M HGLRTNRELLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLADADNIRLS
MUL_4706|M.ulcerans_Agy99 HGLRTNRELLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLADADNIRLS
MAV_1089|M.avium_104 HGVRTNRDLLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLGDAAAVRLS
Mflv_1882|M.gilvum_PYR-GCK HGVRTNRDLLVNVLRHPAFRDGATDTAFFETHGLSALAAPVAGERTVALA
Mvan_4849|M.vanbaalenii_PYR-1 HGVRTNRDLLVNVLRHPAFGDGATDTAFFDTHGLAELAAPVADDRTVALS
MSMEG_5493|M.smegmatis_MC2_155 HGVRTNRDLLVNVLRHPAFLDGATDTAFFDTHGLDVLAAPLTTPVAARAS
MAB_1071c|M.abscessus_ATCC_199 HGLTTNRDLLVNVLRHPAFLDGDTDTSFLDKHGLDTLARPLADEAAHQYS
TH_3286|M.thermoresistible__bu LGLTTNIEFLRFLLADDDVAAGRLDTGLLDRCAPDFTPAGATDAELIAAG
MLBr_00726|M.leprae_Br4923 EGLATVIPFHRAVVSDPALIG---DNNSFSVH----------------TR
*: * : :: . . *. :.
Rv0973c|M.tuberculosis_H37Rv AIAAALADAEHNRASAGVFSSIPSGWRNLA---SGYQVKTYRDDADTEHR
Mb0998c|M.bovis_AF2122/97 AIAAALADAEHNRASAGVFSSIPSGWRNLA---SGYQVKTYRDDADTEHR
MMAR_4534|M.marinum_M ATAAALADAAHNRATATVFGSIPSGWRNVA---SGYQVKTYRDGGDVEHR
MUL_4706|M.ulcerans_Agy99 AIAAALADAAHNRATATVFGSIPSGWRNVA---SGYQVKTYRDGGDVEYR
MAV_1089|M.avium_104 AVAAALADAARNRAHAPVLGAIPSGWRNLP---SGFQVKDYRDDEGHEHR
Mflv_1882|M.gilvum_PYR-GCK AIAAALADAAHNRATARVLGAVPGGWRNLP---SAFQVKAFRDATGETQE
Mvan_4849|M.vanbaalenii_PYR-1 AVAAALADAAHNRSTATVFEDIPSGWRNLP---AGFQHKSYQDHAGRAHD
MSMEG_5493|M.smegmatis_MC2_155 AIAATLADAAHNRSAAEAFLPAPSGWRNLA---SGYQQRRYHDASGEEVE
MAB_1071c|M.abscessus_ATCC_199 ALAAALADAAANRAAAVACAAVPSGWRNLRGPSSGFQTKEFVAG-DSTVR
TH_3286|M.thermoresistible__bu AYHWLQRWAD----AADDLWSQPSGWRVGAQAATSYR-LEAGDRTDHVRL
MLBr_00726|M.leprae_Br4923 WIETEWNNTI----------------------------EPFIDNQPLDEE
:
Rv0973c|M.tuberculosis_H37Rv VEYRFTRTGLALPGD-----PVVQLVSADVDQVVLA-QDGVAHGFTVARH
Mb0998c|M.bovis_AF2122/97 VEYRFTRTGLALPGD-----PVVQLVSADVDQVVLA-QDGVAHGFTVARH
MMAR_4534|M.marinum_M IEYRFTRTGLEIAGD-----DSVRLVSATPNEVVLAGENGVARRFTVASY
MUL_4706|M.ulcerans_Agy99 IEYRFTRTGLQIAGD-----DSVRLVLATPNEVVLAGENGVARRFTVASY
MAV_1089|M.avium_104 VQYRFTRTGLVLPDD-----PSVQLVSATADDVVLR-TDGVEHNFSVRRY
Mflv_1882|M.gilvum_PYR-GCK VRYRFTRAGLTLDGH-----DDVELVSATSHHVVLS-VAGVDRPFDVHRY
Mvan_4849|M.vanbaalenii_PYR-1 VRYRFTRDGVMIDGH-----DDVSVVSAGQRQVVLT-VSGVDRPFDVTRY
MSMEG_5493|M.smegmatis_MC2_155 VRYRFARDGLRLPDD-----ENVALVSATPARVVLG-LDGVEYTFDVARH
MAB_1071c|M.abscessus_ATCC_199 VRYRLTRTGLELDGASDTAWPTIELVSATPEHVALV-IDGVRRGFDVANY
TH_3286|M.thermoresistible__bu TGHPYDATVAIEDGD------PRPLTAALTGSRLTVTVDGLRTDYTVAAA
MLBr_00726|M.leprae_Br4923 DTRPQQTVIVEVDGR--------RLEVSLPADLALANPAGCN--------
. : : *
Rv0973c|M.tuberculosis_H37Rv G---PDVYVDSARGPVHLVALSRFPEPSSAVEQG--SLVAPMPGNVIRIG
Mb0998c|M.bovis_AF2122/97 G---PDVYVDSARGPVHLVALSRFPEPSSAVEQG--SLVAPMPGNVIRIG
MMAR_4534|M.marinum_M G---QDVFVDSPSGPVHLVALPRFPEPGSAVEQG--SLVAPMPGNVIRLG
MUL_4706|M.ulcerans_Agy99 G---QDVFVDSPSGPVHLVALPRFPEPGSAVEQG--SLVAPMPGNVIRLG
MAV_1089|M.avium_104 HGADADVYVDSVRGPVHLTVLPRFPEPGSSVEKG--SLVAPMPGNVIRLG
Mflv_1882|M.gilvum_PYR-GCK GA---DVHVDSPGGSVHLVALSRFPDPDAAPAHG--SLLAPMPGSVLRVA
Mvan_4849|M.vanbaalenii_PYR-1 GD---SVFVDSPCGCTHFVALPRFPDPAAALAHG--SLLAPMPGSVLRVG
MSMEG_5493|M.smegmatis_MC2_155 GDDVFDVFVDSPLGPVRFTAMPRFPDPGDAVAHG--SLLAPMPGTVVRVG
MAB_1071c|M.abscessus_ATCC_199 G---DTVDIDSPLGPVALTVVPRFTDPSTEVAAG--SLIAPMPGVVLRLG
TH_3286|M.thermoresistible__bu DG---RLWLAAAGRAVAVSEVREAPVRPDDEHRGDAELVSPMPGSVVALG
MLBr_00726|M.leprae_Br4923 -----------PAGVIRKKPKPRKRGGHTGAATSGDAVTAPMQGTVVKVA
. . : :** * *: :.
Rv0973c|M.tuberculosis_H37Rv AEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAIL
Mb0998c|M.bovis_AF2122/97 AEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAIL
MMAR_4534|M.marinum_M ADVGDAVTAGQPLIWLEAMKMEHTISAPTDGVLTQLNVQTGQQVDVGAVL
MUL_4706|M.ulcerans_Agy99 ADVGDTVTAGQPLIWLEAMKMEHTISAPTDGVLTQLNVQTGQQVDVGAVL
MAV_1089|M.avium_104 AAIGDTVTAGQSLIWLEAMKMEHTIAAPVDGVLAELNVKTGQQVEVGAVL
Mflv_1882|M.gilvum_PYR-GCK AAQGDTVTAGQPLLWLEAMKMEHTITAPADGVLVALNVVAGQQVEVGAVL
Mvan_4849|M.vanbaalenii_PYR-1 AAPGDTVTAGQPLLWLEAMKMEHTITAPTDGVLVELNVEPGRQVEVGAVL
MSMEG_5493|M.smegmatis_MC2_155 ATVGAKVSAGQPLVWLEAMKMEHTVAAPSDGVLTELNVEPGRQVDVGEVL
MAB_1071c|M.abscessus_ATCC_199 AAVGDAVTAGTPIVWLEAMKMEHTIVAPADGVVEILNVEPGQQVELGTVL
TH_3286|M.thermoresistible__bu VSDGDAVDAGTLVVTVEAMKMEHPLTAPVAGVVELL-VAVGDQVKVGQPL
MLBr_00726|M.leprae_Br4923 VAEGQTVMTGDLVVVLEAMKMENPVTAHKDGIITGLAVEAGTAITQGTVL
. * * :* :: :******:.: * *:: : * * : * *
Rv0973c|M.tuberculosis_H37Rv ARVEAPQNGPAEGDSP
Mb0998c|M.bovis_AF2122/97 ARVEAPQNGPAEGDSP
MMAR_4534|M.marinum_M ARVEAP---EAEGDS-
MUL_4706|M.ulcerans_Agy99 ARVEAP---EAEGDS-
MAV_1089|M.avium_104 ARVEAP---QSEGDAQ
Mflv_1882|M.gilvum_PYR-GCK ARVDTGDSGEESR---
Mvan_4849|M.vanbaalenii_PYR-1 ARVESQEG--DPR---
MSMEG_5493|M.smegmatis_MC2_155 ARVEDPEG--EQR---
MAB_1071c|M.abscessus_ATCC_199 AQLAAEATTEGEPA--
TH_3286|M.thermoresistible__bu ARITTE----QED---
MLBr_00726|M.leprae_Br4923 AEIK------------
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