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M. gilvum PYR-GCK Mflv_1882 (-)

annotation: pyruvate carboxylase
coordinates: 1959931 - 1961919
length: 662

ISRVLVANRGEIARRVFATCRRLGIGTVAVYTDPDADAPHVAEADARVRLEGTRGYLDPTQLVAAALASG
ADAIHPGYGFLSEKPDFAAAVQGAELTWIGPPVAAVAAMGSKIEAKKMMAAAGVPVLDELDPDAVTAAML
PVLIKASAGGGGRGMRIVRELAELPIQVAAARREAQSAFGDPTVFCERYLDAGHHVEVQVMADAHGTVWA
LGERECSIQRRHQKIIEEAPSPLVERTPGMRERLFDAARLAAEAIGYTGAGTVEFMASGQGEPGGSFYFL
EMNTRLQVEHPVTELTAGLDLVELQIAVADGAPLDPAPPTPRGAAIEARLYAEDPARNWQPQAGTVAHFD
VPTAACEFGLLERAGVRVDSGVTDGSVISVFYDPMIAKVISYAPSRPQAAALLADALTRTRLHGVRTNRD
LLVNVLRHPAFRDGATDTAFFETHGLSALAAPVAGERTVALAAIAAALADAAHNRATARVLGAVPGGWRN
LPSAFQVKAFRDATGETQEVRYRFTRAGLTLDGHDDVELVSATSHHVVLSVAGVDRPFDVHRYGADVHVD
SPGGSVHLVALSRFPDPDAAPAHGSLLAPMPGSVLRVAAAQGDTVTAGQPLLWLEAMKMEHTITAPADGV
LVALNVVAGQQVEVGAVLARVDTGDSGEESR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1882--100% (662)pyruvate carboxylase
M. gilvum PYR-GCKMflv_4614-e-17752.14% (679) carbamoyl-phosphate synthase L chain, ATP-binding
M. gilvum PYR-GCKMflv_2553-e-12643.36% (685) carbamoyl-phosphate synthase L chain, ATP-binding

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0998caccA20.070.21% (658) acetyl-/propionyl-coenzyme A carboxylase subunit alpha
M. tuberculosis H37RvRv0973caccA20.070.36% (658) acetyl-/propionyl-coenzyme A carboxylase subunit alpha
M. leprae Br4923MLBr_00726bccA4e-8845.01% (431) acetyl/propionyl CoA carboxylase alpha subunit
M. abscessus ATCC 19977MAB_1071c-0.065.48% (675) acetyl-/propionyl-CoA carboxylase alpha subunit AccA2
M. marinum MMMAR_4534accA20.071.60% (662) acetyl-/propionyl-coenzyme A carboxylase alpha chain, AccA2
M. avium 104MAV_1089-0.072.73% (660) carbamoyl-phosphate synthase L subunit
M. smegmatis MC2 155MSMEG_5493-0.072.26% (656) acetyl-/propionyl-coenzyme A carboxylase alpha chain
M. thermoresistible (build 8)TH_3286-1e-13243.67% (671) PUTATIVE acetyl-/propionyl-coenzyme A carboxylase alpha chain
M. ulcerans Agy99MUL_4706accA20.071.90% (662) acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2
M. vanbaalenii PYR-1Mvan_4849-0.081.65% (654) carbamoyl-phosphate synthase L chain, ATP-binding

CLUSTAL 2.0.9 multiple sequence alignment


Mb0998c|M.bovis_AF2122/97           ---------MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
Rv0973c|M.tuberculosis_H37Rv        ---------MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
MMAR_4534|M.marinum_M               -------MPMSITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
MUL_4706|M.ulcerans_Agy99           ---------MSITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP
MAV_1089|M.avium_104                ---------MGITRVLVANRGEIARRVFATCRRLGVSTVAVYTDPDAGAP
Mflv_1882|M.gilvum_PYR-GCK          ----------MISRVLVANRGEIARRVFATCRRLGIGTVAVYTDPDADAP
Mvan_4849|M.vanbaalenii_PYR-1       ----------MITRVLVANRGEIARRVFATCRRLGIGTVAVYTDADAGAP
MSMEG_5493|M.smegmatis_MC2_155      ----------MITRVLVANRCEIARRVFATCRRLGIGTVAVYTDPDADLP
MAB_1071c|M.abscessus_ATCC_199      MTRKESMTVPSITSVLVANRGEIARRVFATCRKLGLGTVAVYSDADADSP
TH_3286|M.thermoresistible__bu      --------------VLVANRGEIAVRVMSTLRRMGIRSVAVFSDADAQAR
MLBr_00726|M.leprae_Br4923          ---MASHASSRIAKVLVANRGEIAVRVIRAARDARLPSVAVYAEPDAEAP
                                                  ****** *** **: : *   : :***:::.**   

Mb0998c|M.bovis_AF2122/97           HVAEADARVRLPQTT---DYLNAEAIIAAAQAAGADAVHPGYGFLSENAE
Rv0973c|M.tuberculosis_H37Rv        HVAEADARVRLPQTT---DYLNAEAIIAAAQAAGADAVHPGYGFLSENAE
MMAR_4534|M.marinum_M               HVAESDARVRLAQTN---DYLNAEAIIAAARAAGADAIHPGYGFLSENPE
MUL_4706|M.ulcerans_Agy99           HVAESDARVRLAQTN---DYLNAEAIIAAARAAGADAIHPGYGFLSENPE
MAV_1089|M.avium_104                HVAEADARVRLPNTT---DYLNIEAIIGAARAAGADALHPGYGFLSENAD
Mflv_1882|M.gilvum_PYR-GCK          HVAEADARVRLEGTR---GYLDPTQLVAAALASGADAIHPGYGFLSEKPD
Mvan_4849|M.vanbaalenii_PYR-1       HVAEADARVRLTGTR---GYLDAAQLIAAARSSGADAIHPGYGFLSENPD
MSMEG_5493|M.smegmatis_MC2_155      HVAEADARVRLQGRN---GYLDIAQIIAAAQASGADAIHPGYGFLSENPD
MAB_1071c|M.abscessus_ATCC_199      HVSEADAAVHLPGTSSAETYLRGELIIAAAKATGADAIHPGYGFLSENAD
TH_3286|M.thermoresistible__bu      HVAEADAAVHIGPAAARHSYLDIEAVVRAARRTGAQAVHPGYGFLSENPE
MLBr_00726|M.leprae_Br4923          HVRLADEAFALGGHTSAESYLDFGKILDAAAKSGANAIHPGYGFLAENAD
                                    **  :*  . :        **    :: **  :**:*:*******:*:.:

Mb0998c|M.bovis_AF2122/97           FAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDP----
Rv0973c|M.tuberculosis_H37Rv        FAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDP----
MMAR_4534|M.marinum_M               FAAAVTAAGLTWIGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP----
MUL_4706|M.ulcerans_Agy99           FAAAVTAAGLTWIGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP----
MAV_1089|M.avium_104                FATAVADAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP----
Mflv_1882|M.gilvum_PYR-GCK          FAAAVQGAELTWIGPPVAAVAAMGSKIEAKKMMAAAGVPVLDELDP----
Mvan_4849|M.vanbaalenii_PYR-1       FAAAVQDAGLRWIGPPVAAVAAMGSKIEAKKLMAAAGVPVLDELDP----
MSMEG_5493|M.smegmatis_MC2_155      FAAAVIDAGLTWIGPPVAAVSAMGSKIEAKKLMAAAGVPVLTELDP----
MAB_1071c|M.abscessus_ATCC_199      FARAVADAGLTWIGPPVAAIESMGSKIESKKLMDAAGVPVLGQLDP----
TH_3286|M.thermoresistible__bu      FAAALADAGIVFIGPPAAAIRTMGDKIAARAAVSAFGVPVVPGISRPGLT
MLBr_00726|M.leprae_Br4923          FAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPGTPDPVKN
                                    ** *:  * : ::**.  ::  :*.*: ::       .*::         

Mb0998c|M.bovis_AF2122/97           -----DAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQS
Rv0973c|M.tuberculosis_H37Rv        -----DAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQS
MMAR_4534|M.marinum_M               -----ETVTATQLPVLVKASAGGGGRGMRVVRELSALPAEVEAARREAQS
MUL_4706|M.ulcerans_Agy99           -----ETVTAAQLPVLVKASAGGGGRGMRVVRELSALPAEVEAARREAQS
MAV_1089|M.avium_104                -----DTVTEAQLPVLVKASAGGGGRGMRVVHELSALRGEVEAARREAQS
Mflv_1882|M.gilvum_PYR-GCK          -----DAVTAAMLPVLIKASAGGGGRGMRIVRELAELPIQVAAARREAQS
Mvan_4849|M.vanbaalenii_PYR-1       -----DTVTADMLPVLVKASAGGGGRGMRVVRDLAELPAQVEAARREAQS
MSMEG_5493|M.smegmatis_MC2_155      -----DTVTAEQLPVLVKASAGGGGRGMRVVGDLAALPDEVAAAQREAQS
MAB_1071c|M.abscessus_ATCC_199      -----ETVTTAQLPVLVKASAGGGGRGMRIVSELDKLPAEIAAAQREAQS
TH_3286|M.thermoresistible__bu      DADLIDGAAQVGFPVLVKPSAGGGGKGMRVVHDPADLPAALAAARREAAA
MLBr_00726|M.leprae_Br4923          ADEVVAFAKEHGVPIAIKAAFGGGGKGMKVARTLEEISELYESAVREATV
                                           .    .*: :*.: ****:**::.     :     :* ***  

Mb0998c|M.bovis_AF2122/97           AFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSFQRRHQKIIE
Rv0973c|M.tuberculosis_H37Rv        AFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSIQRRHQKIIE
MMAR_4534|M.marinum_M               AFGDPTVFCERYLPTGHHIEVQVMADTHGTVWAVGERECSIQRRHQKIIE
MUL_4706|M.ulcerans_Agy99           AFGDPTVFCERYLPTGHHIEVQVMADTHGTVWAVGERECSIQRRHQKIIE
MAV_1089|M.avium_104                AFGDPTVFCERYLPTGHHVEVQVLADAHGTVWAVGERECSIQRRHQKIIE
Mflv_1882|M.gilvum_PYR-GCK          AFGDPTVFCERYLDAGHHVEVQVMADAHGTVWALGERECSIQRRHQKIIE
Mvan_4849|M.vanbaalenii_PYR-1       AFGDPTVFCERYLDAGHHVEVQVMADVHGTVWAVGERECSIQRRHQKIIE
MSMEG_5493|M.smegmatis_MC2_155      AFGDPTVFCEHYLAAGHHVEVQVLADAHGTVWTVGERECSIQRRHQKVIE
MAB_1071c|M.abscessus_ATCC_199      AFGDPTVFCERYLGTGRHIEVQVMADAHGTVWAVGERECSIQRRHQKVIE
TH_3286|M.thermoresistible__bu      AFGDDTLFLERFVLNPRHIEVQVLADQHGNVIHLGERECSLQRRHQKVIE
MLBr_00726|M.leprae_Br4923          AFGRGECFVERYLDKPRHVEAQVIADQHGNIVVAGTRDCSLQRRFQKLVE
                                    ***    * *:::   :*:*.**:** **.:   * *:**:***.**::*

Mb0998c|M.bovis_AF2122/97           EAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEF
Rv0973c|M.tuberculosis_H37Rv        EAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEF
MMAR_4534|M.marinum_M               EAPSPLVQRIPGMRAKLFDAARLAAEAIGYTGAGTVEFLADDA----GEF
MUL_4706|M.ulcerans_Agy99           EAPSPLVQRIPGMRAKLFDAARLAAEAIGYTGAGTVEFLADDA----GEF
MAV_1089|M.avium_104                EAPSPLVERTPGMRAKLFEAARLAAGVIGYTGAGTVEFLADDD----GEF
Mflv_1882|M.gilvum_PYR-GCK          EAPSPLVERTPGMRERLFDAARLAAEAIGYTGAGTVEFMASGQGEPGGSF
Mvan_4849|M.vanbaalenii_PYR-1       EAPSPLVERVAGMRDKLFEAARLAATAIGYSGAGTVEFMADDQG----AF
MSMEG_5493|M.smegmatis_MC2_155      EAPSPLVERTPGMRAKLFDAARLAAQAIGYTGAGTVEFMADDNG----DF
MAB_1071c|M.abscessus_ATCC_199      EAPSPLVTRIDGMRERLFQASRTAAAAIGYVGAGTMEFLATEDG----EF
TH_3286|M.thermoresistible__bu      EAPSPLLDAAT--RERIGSAACDTARSVDYTGAGTVEFIVSADR--PDEF
MLBr_00726|M.leprae_Br4923          EAPAPFLTDAQ--RKEIHESAKRICKEAHYYGAGTVEYLVGQDG----LI
                                    ***:*::      * .: .::   .    * ****:*::.         :

Mb0998c|M.bovis_AF2122/97           YFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPP--PAQGYS
Rv0973c|M.tuberculosis_H37Rv        YFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPP--PAQGYS
MMAR_4534|M.marinum_M               YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGGRLQAEPP--PAHGHS
MUL_4706|M.ulcerans_Agy99           YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGGRLLAEPP--PAHGHS
MAV_1089|M.avium_104                YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGARLDAEPP--AAQGYS
Mflv_1882|M.gilvum_PYR-GCK          YFLEMNTRLQVEHPVTELTAGLDLVELQIAVADGAPLDPAPP--TPRGAA
Mvan_4849|M.vanbaalenii_PYR-1       FFLEMNTRLQVEHPVTELTSGVDLVELQLAVADGATLDPSPP--APRGAS
MSMEG_5493|M.smegmatis_MC2_155      FFLEMNTRLQVEHPVTEATTGLDLVELQLLVADGGRLDPEPP--PTRGAA
MAB_1071c|M.abscessus_ATCC_199      FFLEMNTRLQVEHPVTECTTGLDLVALQIQVADGGTLPAEPP--AIQGHS
TH_3286|M.thermoresistible__bu      FFMEMNTRLQVEHPVTEMVTGVDLVEQQIRIAAGEKLAIAQDDVTLSGHA
MLBr_00726|M.leprae_Br4923          SFLEVNTRLQVEHPVTEETTGIDLVLQQFKIANGEKLELIKDP-IPCGHA
                                     *:*:************ .:*:***  *: :*    *          * :

Mb0998c|M.bovis_AF2122/97           IEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQ--RTGIRLDSGI
Rv0973c|M.tuberculosis_H37Rv        IEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQ--RTGIRLDSGI
MMAR_4534|M.marinum_M               IEARLYAEDPAQGWQPQAGAMHTIEVPSVRAEFATLGQ--RTGIRLDSGI
MUL_4706|M.ulcerans_Agy99           IEARLYAEDPAQGWQPQAGAMHTIEVPSVRAEFATLGQ--RTGIRLDSGI
MAV_1089|M.avium_104                IEARLYAEDPARGWQPQAGVVHAFAVPSVRAEFGSLGR--RIGIRLDAGI
Mflv_1882|M.gilvum_PYR-GCK          IEARLYAEDPARNWQPQAGTVAHFDVPTAACEFGLL-E--RAGVRVDSGV
Mvan_4849|M.vanbaalenii_PYR-1       IEARLYAEDPANNWQPQPGAVHHFDVPTAGVEFGPL-D--RTGVRLDSGI
MSMEG_5493|M.smegmatis_MC2_155      IEARIYAEDPAKDWQPQAGTLHRFDFPEN--------------VRTDTGF
MAB_1071c|M.abscessus_ATCC_199      IEARLYAENPAAGWQPQSGTVRRFDIPGATAEFHLPGHPGRNGVRLDSMI
TH_3286|M.thermoresistible__bu      VEARIYAEDPAAGFLPTGGTVLHVAEPDHP------------GVRVDSGL
MLBr_00726|M.leprae_Br4923          IEFRINGEDAGRNFLPSPGPVSKFHPPTGP------------GVRLDSGV
                                    :* *: .*:.. .: *  * :  .  *                :* *: .

Mb0998c|M.bovis_AF2122/97           VD----------GSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARL
Rv0973c|M.tuberculosis_H37Rv        VD----------GSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARL
MMAR_4534|M.marinum_M               VD----------GSVVSIHYDPMLAKVISYAPTRRQSALVLADALARAHL
MUL_4706|M.ulcerans_Agy99           VD----------GSVVSIHYDPMLAKVISYAPTRRQSALVLADALARAHL
MAV_1089|M.avium_104                TD----------GFAVSIHYDPMLAKVISYAPTRRQAALVLADALTRTRV
Mflv_1882|M.gilvum_PYR-GCK          TD----------GSVISVFYDPMIAKVISYAPSRPQAAALLADALTRTRL
Mvan_4849|M.vanbaalenii_PYR-1       TD----------GAVISVFYDPMIAKVISYAPTRRQAAALLADALTRARI
MSMEG_5493|M.smegmatis_MC2_155      VD----------GSVVSVFYDSMLAKVIAHAPTRRRAAAVLADALARARI
MAB_1071c|M.abscessus_ATCC_199      ETGAEVEGRPLRGSTVSVHYDPMLAKVITVAPTRTEAARLLASTLERARI
TH_3286|M.thermoresistible__bu      FD----------GTVVGSDYDPMLAKVIAHGPDRATALRTLDRALADTAI
MLBr_00726|M.leprae_Br4923          ET----------GSVIGGQFDSMLAKLIVHGATRQEALARARRALDEFEV
                                                * .:.  :*.*:**::  .. *  :      :*    :

Mb0998c|M.bovis_AF2122/97           HGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLS
Rv0973c|M.tuberculosis_H37Rv        HGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLS
MMAR_4534|M.marinum_M               HGLRTNRELLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLADADNIRLS
MUL_4706|M.ulcerans_Agy99           HGLRTNRELLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLADADNIRLS
MAV_1089|M.avium_104                HGVRTNRDLLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLGDAAAVRLS
Mflv_1882|M.gilvum_PYR-GCK          HGVRTNRDLLVNVLRHPAFRDGATDTAFFETHGLSALAAPVAGERTVALA
Mvan_4849|M.vanbaalenii_PYR-1       HGVRTNRDLLVNVLRHPAFGDGATDTAFFDTHGLAELAAPVADDRTVALS
MSMEG_5493|M.smegmatis_MC2_155      HGVRTNRDLLVNVLRHPAFLDGATDTAFFDTHGLDVLAAPLTTPVAARAS
MAB_1071c|M.abscessus_ATCC_199      HGLTTNRDLLVNVLRHPAFLDGDTDTSFLDKHGLDTLARPLADEAAHQYS
TH_3286|M.thermoresistible__bu      LGLTTNIEFLRFLLADDDVAAGRLDTGLLDRCAPDFTPAGATDAELIAAG
MLBr_00726|M.leprae_Br4923          EGLATVIPFHRAVVSDPALIG---DNNSFSVH----------------TR
                                     *: *   :   :: .  .     *.  :.                    

Mb0998c|M.bovis_AF2122/97           AIAAALADAEHNRASAGVFSSIPSGWRNLA---SGYQVKTYRDDADTEHR
Rv0973c|M.tuberculosis_H37Rv        AIAAALADAEHNRASAGVFSSIPSGWRNLA---SGYQVKTYRDDADTEHR
MMAR_4534|M.marinum_M               ATAAALADAAHNRATATVFGSIPSGWRNVA---SGYQVKTYRDGGDVEHR
MUL_4706|M.ulcerans_Agy99           AIAAALADAAHNRATATVFGSIPSGWRNVA---SGYQVKTYRDGGDVEYR
MAV_1089|M.avium_104                AVAAALADAARNRAHAPVLGAIPSGWRNLP---SGFQVKDYRDDEGHEHR
Mflv_1882|M.gilvum_PYR-GCK          AIAAALADAAHNRATARVLGAVPGGWRNLP---SAFQVKAFRDATGETQE
Mvan_4849|M.vanbaalenii_PYR-1       AVAAALADAAHNRSTATVFEDIPSGWRNLP---AGFQHKSYQDHAGRAHD
MSMEG_5493|M.smegmatis_MC2_155      AIAATLADAAHNRSAAEAFLPAPSGWRNLA---SGYQQRRYHDASGEEVE
MAB_1071c|M.abscessus_ATCC_199      ALAAALADAAANRAAAVACAAVPSGWRNLRGPSSGFQTKEFVAG-DSTVR
TH_3286|M.thermoresistible__bu      AYHWLQRWAD----AADDLWSQPSGWRVGAQAATSYR-LEAGDRTDHVRL
MLBr_00726|M.leprae_Br4923          WIETEWNNTI----------------------------EPFIDNQPLDEE
                                            :                                         

Mb0998c|M.bovis_AF2122/97           VEYRFTRTGLALPGD-----PVVQLVSADVDQVVLA-QDGVAHGFTVARH
Rv0973c|M.tuberculosis_H37Rv        VEYRFTRTGLALPGD-----PVVQLVSADVDQVVLA-QDGVAHGFTVARH
MMAR_4534|M.marinum_M               IEYRFTRTGLEIAGD-----DSVRLVSATPNEVVLAGENGVARRFTVASY
MUL_4706|M.ulcerans_Agy99           IEYRFTRTGLQIAGD-----DSVRLVLATPNEVVLAGENGVARRFTVASY
MAV_1089|M.avium_104                VQYRFTRTGLVLPDD-----PSVQLVSATADDVVLR-TDGVEHNFSVRRY
Mflv_1882|M.gilvum_PYR-GCK          VRYRFTRAGLTLDGH-----DDVELVSATSHHVVLS-VAGVDRPFDVHRY
Mvan_4849|M.vanbaalenii_PYR-1       VRYRFTRDGVMIDGH-----DDVSVVSAGQRQVVLT-VSGVDRPFDVTRY
MSMEG_5493|M.smegmatis_MC2_155      VRYRFARDGLRLPDD-----ENVALVSATPARVVLG-LDGVEYTFDVARH
MAB_1071c|M.abscessus_ATCC_199      VRYRLTRTGLELDGASDTAWPTIELVSATPEHVALV-IDGVRRGFDVANY
TH_3286|M.thermoresistible__bu      TGHPYDATVAIEDGD------PRPLTAALTGSRLTVTVDGLRTDYTVAAA
MLBr_00726|M.leprae_Br4923          DTRPQQTVIVEVDGR--------RLEVSLPADLALANPAGCN--------
                                                 .          :  :           *          

Mb0998c|M.bovis_AF2122/97           G---PDVYVDSARGPVHLVALSRFPEPSSAVEQG--SLVAPMPGNVIRIG
Rv0973c|M.tuberculosis_H37Rv        G---PDVYVDSARGPVHLVALSRFPEPSSAVEQG--SLVAPMPGNVIRIG
MMAR_4534|M.marinum_M               G---QDVFVDSPSGPVHLVALPRFPEPGSAVEQG--SLVAPMPGNVIRLG
MUL_4706|M.ulcerans_Agy99           G---QDVFVDSPSGPVHLVALPRFPEPGSAVEQG--SLVAPMPGNVIRLG
MAV_1089|M.avium_104                HGADADVYVDSVRGPVHLTVLPRFPEPGSSVEKG--SLVAPMPGNVIRLG
Mflv_1882|M.gilvum_PYR-GCK          GA---DVHVDSPGGSVHLVALSRFPDPDAAPAHG--SLLAPMPGSVLRVA
Mvan_4849|M.vanbaalenii_PYR-1       GD---SVFVDSPCGCTHFVALPRFPDPAAALAHG--SLLAPMPGSVLRVG
MSMEG_5493|M.smegmatis_MC2_155      GDDVFDVFVDSPLGPVRFTAMPRFPDPGDAVAHG--SLLAPMPGTVVRVG
MAB_1071c|M.abscessus_ATCC_199      G---DTVDIDSPLGPVALTVVPRFTDPSTEVAAG--SLIAPMPGVVLRLG
TH_3286|M.thermoresistible__bu      DG---RLWLAAAGRAVAVSEVREAPVRPDDEHRGDAELVSPMPGSVVALG
MLBr_00726|M.leprae_Br4923          -----------PAGVIRKKPKPRKRGGHTGAATSGDAVTAPMQGTVVKVA
                                                          .          .   : :** * *: :.

Mb0998c|M.bovis_AF2122/97           AEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAIL
Rv0973c|M.tuberculosis_H37Rv        AEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAIL
MMAR_4534|M.marinum_M               ADVGDAVTAGQPLIWLEAMKMEHTISAPTDGVLTQLNVQTGQQVDVGAVL
MUL_4706|M.ulcerans_Agy99           ADVGDTVTAGQPLIWLEAMKMEHTISAPTDGVLTQLNVQTGQQVDVGAVL
MAV_1089|M.avium_104                AAIGDTVTAGQSLIWLEAMKMEHTIAAPVDGVLAELNVKTGQQVEVGAVL
Mflv_1882|M.gilvum_PYR-GCK          AAQGDTVTAGQPLLWLEAMKMEHTITAPADGVLVALNVVAGQQVEVGAVL
Mvan_4849|M.vanbaalenii_PYR-1       AAPGDTVTAGQPLLWLEAMKMEHTITAPTDGVLVELNVEPGRQVEVGAVL
MSMEG_5493|M.smegmatis_MC2_155      ATVGAKVSAGQPLVWLEAMKMEHTVAAPSDGVLTELNVEPGRQVDVGEVL
MAB_1071c|M.abscessus_ATCC_199      AAVGDAVTAGTPIVWLEAMKMEHTIVAPADGVVEILNVEPGQQVELGTVL
TH_3286|M.thermoresistible__bu      VSDGDAVDAGTLVVTVEAMKMEHPLTAPVAGVVELL-VAVGDQVKVGQPL
MLBr_00726|M.leprae_Br4923          VAEGQTVMTGDLVVVLEAMKMENPVTAHKDGIITGLAVEAGTAITQGTVL
                                    .  *  * :*  :: :******:.: *   *::  : *  *  :  *  *

Mb0998c|M.bovis_AF2122/97           ARVEAPQNGPAEGDSP
Rv0973c|M.tuberculosis_H37Rv        ARVEAPQNGPAEGDSP
MMAR_4534|M.marinum_M               ARVEAP---EAEGDS-
MUL_4706|M.ulcerans_Agy99           ARVEAP---EAEGDS-
MAV_1089|M.avium_104                ARVEAP---QSEGDAQ
Mflv_1882|M.gilvum_PYR-GCK          ARVDTGDSGEESR---
Mvan_4849|M.vanbaalenii_PYR-1       ARVESQEG--DPR---
MSMEG_5493|M.smegmatis_MC2_155      ARVEDPEG--EQR---
MAB_1071c|M.abscessus_ATCC_199      AQLAAEATTEGEPA--
TH_3286|M.thermoresistible__bu      ARITTE----QED---
MLBr_00726|M.leprae_Br4923          AEIK------------
                                    *.: