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MITRVLVANRGEIARRVFATCRRLGIGTVAVYTDADAGAPHVAEADARVRLTGTRGYLDAAQLIAAARSS GADAIHPGYGFLSENPDFAAAVQDAGLRWIGPPVAAVAAMGSKIEAKKLMAAAGVPVLDELDPDTVTADM LPVLVKASAGGGGRGMRVVRDLAELPAQVEAARREAQSAFGDPTVFCERYLDAGHHVEVQVMADVHGTVW AVGERECSIQRRHQKIIEEAPSPLVERVAGMRDKLFEAARLAATAIGYSGAGTVEFMADDQGAFFFLEMN TRLQVEHPVTELTSGVDLVELQLAVADGATLDPSPPAPRGASIEARLYAEDPANNWQPQPGAVHHFDVPT AGVEFGPLDRTGVRLDSGITDGAVISVFYDPMIAKVISYAPTRRQAAALLADALTRARIHGVRTNRDLLV NVLRHPAFGDGATDTAFFDTHGLAELAAPVADDRTVALSAVAAALADAAHNRSTATVFEDIPSGWRNLPA GFQHKSYQDHAGRAHDVRYRFTRDGVMIDGHDDVSVVSAGQRQVVLTVSGVDRPFDVTRYGDSVFVDSPC GCTHFVALPRFPDPAAALAHGSLLAPMPGSVLRVGAAPGDTVTAGQPLLWLEAMKMEHTITAPTDGVLVE LNVEPGRQVEVGAVLARVESQEGDPR
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_4849 | - | - | 100% (656) | carbamoyl-phosphate synthase L chain, ATP-binding |
M. vanbaalenii PYR-1 | Mvan_0345 | - | e-162 | 49.25% (670) | carbamoyl-phosphate synthase L chain, ATP-binding |
M. vanbaalenii PYR-1 | Mvan_4090 | - | e-132 | 44.74% (675) | carbamoyl-phosphate synthase L chain, ATP-binding |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0998c | accA2 | 0.0 | 71.78% (659) | acetyl-/propionyl-coenzyme A carboxylase subunit alpha |
M. gilvum PYR-GCK | Mflv_1882 | - | 0.0 | 81.65% (654) | pyruvate carboxylase |
M. tuberculosis H37Rv | Rv0973c | accA2 | 0.0 | 71.93% (659) | acetyl-/propionyl-coenzyme A carboxylase subunit alpha |
M. leprae Br4923 | MLBr_00726 | bccA | 1e-103 | 38.17% (668) | acetyl/propionyl CoA carboxylase alpha subunit |
M. abscessus ATCC 19977 | MAB_1071c | - | 0.0 | 65.05% (681) | acetyl-/propionyl-CoA carboxylase alpha subunit AccA2 |
M. marinum M | MMAR_4534 | accA2 | 0.0 | 75.11% (655) | acetyl-/propionyl-coenzyme A carboxylase alpha chain, AccA2 |
M. avium 104 | MAV_1089 | - | 0.0 | 74.51% (659) | carbamoyl-phosphate synthase L subunit |
M. smegmatis MC2 155 | MSMEG_5493 | - | 0.0 | 74.51% (659) | acetyl-/propionyl-coenzyme A carboxylase alpha chain |
M. thermoresistible (build 8) | TH_3286 | - | 1e-134 | 45.21% (679) | PUTATIVE acetyl-/propionyl-coenzyme A carboxylase alpha chain |
M. ulcerans Agy99 | MUL_4706 | accA2 | 0.0 | 74.96% (655) | acetyl-/propionyl-coenzyme a carboxylase alpha chain, AccA2 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0998c|M.bovis_AF2122/97 ---------MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP Rv0973c|M.tuberculosis_H37Rv ---------MGITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP MMAR_4534|M.marinum_M -------MPMSITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP MUL_4706|M.ulcerans_Agy99 ---------MSITRVLVANRGEIARRVFATCRRLGLGTVAVYTDPDAAAP MAV_1089|M.avium_104 ---------MGITRVLVANRGEIARRVFATCRRLGVSTVAVYTDPDAGAP Mvan_4849|M.vanbaalenii_PYR-1 ----------MITRVLVANRGEIARRVFATCRRLGIGTVAVYTDADAGAP Mflv_1882|M.gilvum_PYR-GCK ----------MISRVLVANRGEIARRVFATCRRLGIGTVAVYTDPDADAP MSMEG_5493|M.smegmatis_MC2_155 ----------MITRVLVANRCEIARRVFATCRRLGIGTVAVYTDPDADLP MAB_1071c|M.abscessus_ATCC_199 MTRKESMTVPSITSVLVANRGEIARRVFATCRKLGLGTVAVYSDADADSP TH_3286|M.thermoresistible__bu --------------VLVANRGEIAVRVMSTLRRMGIRSVAVFSDADAQAR MLBr_00726|M.leprae_Br4923 ---MASHASSRIAKVLVANRGEIAVRVIRAARDARLPSVAVYAEPDAEAP ****** *** **: : * : :***:::.** Mb0998c|M.bovis_AF2122/97 HVAEADARVRLPQTT---DYLNAEAIIAAAQAAGADAVHPGYGFLSENAE Rv0973c|M.tuberculosis_H37Rv HVAEADARVRLPQTT---DYLNAEAIIAAAQAAGADAVHPGYGFLSENAE MMAR_4534|M.marinum_M HVAESDARVRLAQTN---DYLNAEAIIAAARAAGADAIHPGYGFLSENPE MUL_4706|M.ulcerans_Agy99 HVAESDARVRLAQTN---DYLNAEAIIAAARAAGADAIHPGYGFLSENPE MAV_1089|M.avium_104 HVAEADARVRLPNTT---DYLNIEAIIGAARAAGADALHPGYGFLSENAD Mvan_4849|M.vanbaalenii_PYR-1 HVAEADARVRLTGTR---GYLDAAQLIAAARSSGADAIHPGYGFLSENPD Mflv_1882|M.gilvum_PYR-GCK HVAEADARVRLEGTR---GYLDPTQLVAAALASGADAIHPGYGFLSEKPD MSMEG_5493|M.smegmatis_MC2_155 HVAEADARVRLQGRN---GYLDIAQIIAAAQASGADAIHPGYGFLSENPD MAB_1071c|M.abscessus_ATCC_199 HVSEADAAVHLPGTSSAETYLRGELIIAAAKATGADAIHPGYGFLSENAD TH_3286|M.thermoresistible__bu HVAEADAAVHIGPAAARHSYLDIEAVVRAARRTGAQAVHPGYGFLSENPE MLBr_00726|M.leprae_Br4923 HVRLADEAFALGGHTSAESYLDFGKILDAAAKSGANAIHPGYGFLAENAD ** :* . : ** :: ** :**:*:*******:*:.: Mb0998c|M.bovis_AF2122/97 FAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDP---- Rv0973c|M.tuberculosis_H37Rv FAAAVQEAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLEELDP---- MMAR_4534|M.marinum_M FAAAVTAAGLTWIGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP---- MUL_4706|M.ulcerans_Agy99 FAAAVTAAGLTWIGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP---- MAV_1089|M.avium_104 FATAVADAGLTWVGPPVDAVRAMGSKIESKKLMAAAGVPVLDELDP---- Mvan_4849|M.vanbaalenii_PYR-1 FAAAVQDAGLRWIGPPVAAVAAMGSKIEAKKLMAAAGVPVLDELDP---- Mflv_1882|M.gilvum_PYR-GCK FAAAVQGAELTWIGPPVAAVAAMGSKIEAKKMMAAAGVPVLDELDP---- MSMEG_5493|M.smegmatis_MC2_155 FAAAVIDAGLTWIGPPVAAVSAMGSKIEAKKLMAAAGVPVLTELDP---- MAB_1071c|M.abscessus_ATCC_199 FARAVADAGLTWIGPPVAAIESMGSKIESKKLMDAAGVPVLGQLDP---- TH_3286|M.thermoresistible__bu FAAALADAGIVFIGPPAAAIRTMGDKIAARAAVSAFGVPVVPGISRPGLT MLBr_00726|M.leprae_Br4923 FAQAVIDAGLIWIGPSPQSIRDLGDKVTARHIAARAQAPLVPGTPDPVKN ** *: * : ::**. :: :*.*: :: .*:: Mb0998c|M.bovis_AF2122/97 -----DAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQS Rv0973c|M.tuberculosis_H37Rv -----DAVTTAQLPVLVKASAGGGGRGMRVVHELSALPAEVEAARREAQS MMAR_4534|M.marinum_M -----ETVTATQLPVLVKASAGGGGRGMRVVRELSALPAEVEAARREAQS MUL_4706|M.ulcerans_Agy99 -----ETVTAAQLPVLVKASAGGGGRGMRVVRELSALPAEVEAARREAQS MAV_1089|M.avium_104 -----DTVTEAQLPVLVKASAGGGGRGMRVVHELSALRGEVEAARREAQS Mvan_4849|M.vanbaalenii_PYR-1 -----DTVTADMLPVLVKASAGGGGRGMRVVRDLAELPAQVEAARREAQS Mflv_1882|M.gilvum_PYR-GCK -----DAVTAAMLPVLIKASAGGGGRGMRIVRELAELPIQVAAARREAQS MSMEG_5493|M.smegmatis_MC2_155 -----DTVTAEQLPVLVKASAGGGGRGMRVVGDLAALPDEVAAAQREAQS MAB_1071c|M.abscessus_ATCC_199 -----ETVTTAQLPVLVKASAGGGGRGMRIVSELDKLPAEIAAAQREAQS TH_3286|M.thermoresistible__bu DADLIDGAAQVGFPVLVKPSAGGGGKGMRVVHDPADLPAALAAARREAAA MLBr_00726|M.leprae_Br4923 ADEVVAFAKEHGVPIAIKAAFGGGGKGMKVARTLEEISELYESAVREATV . .*: :*.: ****:**::. : :* *** Mb0998c|M.bovis_AF2122/97 AFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSFQRRHQKIIE Rv0973c|M.tuberculosis_H37Rv AFGDPTVFCERYLPTGHHVEVQVMADTHGTVWAVGERECSIQRRHQKIIE MMAR_4534|M.marinum_M AFGDPTVFCERYLPTGHHIEVQVMADTHGTVWAVGERECSIQRRHQKIIE MUL_4706|M.ulcerans_Agy99 AFGDPTVFCERYLPTGHHIEVQVMADTHGTVWAVGERECSIQRRHQKIIE MAV_1089|M.avium_104 AFGDPTVFCERYLPTGHHVEVQVLADAHGTVWAVGERECSIQRRHQKIIE Mvan_4849|M.vanbaalenii_PYR-1 AFGDPTVFCERYLDAGHHVEVQVMADVHGTVWAVGERECSIQRRHQKIIE Mflv_1882|M.gilvum_PYR-GCK AFGDPTVFCERYLDAGHHVEVQVMADAHGTVWALGERECSIQRRHQKIIE MSMEG_5493|M.smegmatis_MC2_155 AFGDPTVFCEHYLAAGHHVEVQVLADAHGTVWTVGERECSIQRRHQKVIE MAB_1071c|M.abscessus_ATCC_199 AFGDPTVFCERYLGTGRHIEVQVMADAHGTVWAVGERECSIQRRHQKVIE TH_3286|M.thermoresistible__bu AFGDDTLFLERFVLNPRHIEVQVLADQHGNVIHLGERECSLQRRHQKVIE MLBr_00726|M.leprae_Br4923 AFGRGECFVERYLDKPRHVEAQVIADQHGNIVVAGTRDCSLQRRFQKLVE *** * *::: :*:*.**:** **.: * *:**:***.**::* Mb0998c|M.bovis_AF2122/97 EAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEF Rv0973c|M.tuberculosis_H37Rv EAPSPLVERVPGMRAKLFDAARLAASAIGYTGAGTVEFLADDSPGREGEF MMAR_4534|M.marinum_M EAPSPLVQRIPGMRAKLFDAARLAAEAIGYTGAGTVEFLADDA----GEF MUL_4706|M.ulcerans_Agy99 EAPSPLVQRIPGMRAKLFDAARLAAEAIGYTGAGTVEFLADDA----GEF MAV_1089|M.avium_104 EAPSPLVERTPGMRAKLFEAARLAAGVIGYTGAGTVEFLADDD----GEF Mvan_4849|M.vanbaalenii_PYR-1 EAPSPLVERVAGMRDKLFEAARLAATAIGYSGAGTVEFMADDQG----AF Mflv_1882|M.gilvum_PYR-GCK EAPSPLVERTPGMRERLFDAARLAAEAIGYTGAGTVEFMASGQGEPGGSF MSMEG_5493|M.smegmatis_MC2_155 EAPSPLVERTPGMRAKLFDAARLAAQAIGYTGAGTVEFMADDNG----DF MAB_1071c|M.abscessus_ATCC_199 EAPSPLVTRIDGMRERLFQASRTAAAAIGYVGAGTMEFLATEDG----EF TH_3286|M.thermoresistible__bu EAPSPLLDAAT--RERIGSAACDTARSVDYTGAGTVEFIVSADR--PDEF MLBr_00726|M.leprae_Br4923 EAPAPFLTDAQ--RKEIHESAKRICKEAHYYGAGTVEYLVGQDG----LI ***:*:: * .: .:: . * ****:*::. : Mb0998c|M.bovis_AF2122/97 YFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPP--PAQGYS Rv0973c|M.tuberculosis_H37Rv YFLEMNTRLQVEHPVTEETTGLDLVELQLMIADCGRLDTEPP--PAQGYS MMAR_4534|M.marinum_M YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGGRLQAEPP--PAHGHS MUL_4706|M.ulcerans_Agy99 YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGGRLLAEPP--PAHGHS MAV_1089|M.avium_104 YFLEMNTRLQVEHPVTEETTGLDLVELQLAVADGARLDAEPP--AAQGYS Mvan_4849|M.vanbaalenii_PYR-1 FFLEMNTRLQVEHPVTELTSGVDLVELQLAVADGATLDPSPP--APRGAS Mflv_1882|M.gilvum_PYR-GCK YFLEMNTRLQVEHPVTELTAGLDLVELQIAVADGAPLDPAPP--TPRGAA MSMEG_5493|M.smegmatis_MC2_155 FFLEMNTRLQVEHPVTEATTGLDLVELQLLVADGGRLDPEPP--PTRGAA MAB_1071c|M.abscessus_ATCC_199 FFLEMNTRLQVEHPVTECTTGLDLVALQIQVADGGTLPAEPP--AIQGHS TH_3286|M.thermoresistible__bu FFMEMNTRLQVEHPVTEMVTGVDLVEQQIRIAAGEKLAIAQDDVTLSGHA MLBr_00726|M.leprae_Br4923 SFLEVNTRLQVEHPVTEETTGIDLVLQQFKIANGEKLELIKDP-IPCGHA *:*:************ .:*:*** *: :* * * : Mb0998c|M.bovis_AF2122/97 IEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQ--RTGIRLDSGI Rv0973c|M.tuberculosis_H37Rv IEARLYAEDPAHGWQPQAGVMHTIEVPGVRAQFDSLGQ--RTGIRLDSGI MMAR_4534|M.marinum_M IEARLYAEDPAQGWQPQAGAMHTIEVPSVRAEFATLGQ--RTGIRLDSGI MUL_4706|M.ulcerans_Agy99 IEARLYAEDPAQGWQPQAGAMHTIEVPSVRAEFATLGQ--RTGIRLDSGI MAV_1089|M.avium_104 IEARLYAEDPARGWQPQAGVVHAFAVPSVRAEFGSLGR--RIGIRLDAGI Mvan_4849|M.vanbaalenii_PYR-1 IEARLYAEDPANNWQPQPGAVHHFDVPTAGVEFGPL-D--RTGVRLDSGI Mflv_1882|M.gilvum_PYR-GCK IEARLYAEDPARNWQPQAGTVAHFDVPTAACEFGLL-E--RAGVRVDSGV MSMEG_5493|M.smegmatis_MC2_155 IEARIYAEDPAKDWQPQAGTLHRFDFPEN--------------VRTDTGF MAB_1071c|M.abscessus_ATCC_199 IEARLYAENPAAGWQPQSGTVRRFDIPGATAEFHLPGHPGRNGVRLDSMI TH_3286|M.thermoresistible__bu VEARIYAEDPAAGFLPTGGTVLHVAEPDHP------------GVRVDSGL MLBr_00726|M.leprae_Br4923 IEFRINGEDAGRNFLPSPGPVSKFHPPTGP------------GVRLDSGV :* *: .*:.. .: * * : . * :* *: . Mb0998c|M.bovis_AF2122/97 VD----------GSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARL Rv0973c|M.tuberculosis_H37Rv VD----------GSTVSIHYDPMLAKVVSYGATRRQAALVLADALVRARL MMAR_4534|M.marinum_M VD----------GSVVSIHYDPMLAKVISYAPTRRQSALVLADALARAHL MUL_4706|M.ulcerans_Agy99 VD----------GSVVSIHYDPMLAKVISYAPTRRQSALVLADALARAHL MAV_1089|M.avium_104 TD----------GFAVSIHYDPMLAKVISYAPTRRQAALVLADALTRTRV Mvan_4849|M.vanbaalenii_PYR-1 TD----------GAVISVFYDPMIAKVISYAPTRRQAAALLADALTRARI Mflv_1882|M.gilvum_PYR-GCK TD----------GSVISVFYDPMIAKVISYAPSRPQAAALLADALTRTRL MSMEG_5493|M.smegmatis_MC2_155 VD----------GSVVSVFYDSMLAKVIAHAPTRRRAAAVLADALARARI MAB_1071c|M.abscessus_ATCC_199 ETGAEVEGRPLRGSTVSVHYDPMLAKVITVAPTRTEAARLLASTLERARI TH_3286|M.thermoresistible__bu FD----------GTVVGSDYDPMLAKVIAHGPDRATALRTLDRALADTAI MLBr_00726|M.leprae_Br4923 ET----------GSVIGGQFDSMLAKLIVHGATRQEALARARRALDEFEV * .:. :*.*:**:: .. * : :* : Mb0998c|M.bovis_AF2122/97 HGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLS Rv0973c|M.tuberculosis_H37Rv HGLRTNRELLVNVLRHPAFLDGATDTGFFDTHGMAELSTPLADTATLRLS MMAR_4534|M.marinum_M HGLRTNRELLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLADADNIRLS MUL_4706|M.ulcerans_Agy99 HGLRTNRELLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLADADNIRLS MAV_1089|M.avium_104 HGVRTNRDLLVNVLRHPAFLDGATDTAFFDTHGLAELAAPLGDAAAVRLS Mvan_4849|M.vanbaalenii_PYR-1 HGVRTNRDLLVNVLRHPAFGDGATDTAFFDTHGLAELAAPVADDRTVALS Mflv_1882|M.gilvum_PYR-GCK HGVRTNRDLLVNVLRHPAFRDGATDTAFFETHGLSALAAPVAGERTVALA MSMEG_5493|M.smegmatis_MC2_155 HGVRTNRDLLVNVLRHPAFLDGATDTAFFDTHGLDVLAAPLTTPVAARAS MAB_1071c|M.abscessus_ATCC_199 HGLTTNRDLLVNVLRHPAFLDGDTDTSFLDKHGLDTLARPLADEAAHQYS TH_3286|M.thermoresistible__bu LGLTTNIEFLRFLLADDDVAAGRLDTGLLDRCAPDFTPAGATDAELIAAG MLBr_00726|M.leprae_Br4923 EGLATVIPFHRAVVSDPALIG---DNNSFSVH----------------TR *: * : :: . . *. :. Mb0998c|M.bovis_AF2122/97 AIAAALADAEHNRASAGVFSSIPSGWRNLA---SGYQVKTYRDDADTEHR Rv0973c|M.tuberculosis_H37Rv AIAAALADAEHNRASAGVFSSIPSGWRNLA---SGYQVKTYRDDADTEHR MMAR_4534|M.marinum_M ATAAALADAAHNRATATVFGSIPSGWRNVA---SGYQVKTYRDGGDVEHR MUL_4706|M.ulcerans_Agy99 AIAAALADAAHNRATATVFGSIPSGWRNVA---SGYQVKTYRDGGDVEYR MAV_1089|M.avium_104 AVAAALADAARNRAHAPVLGAIPSGWRNLP---SGFQVKDYRDDEGHEHR Mvan_4849|M.vanbaalenii_PYR-1 AVAAALADAAHNRSTATVFEDIPSGWRNLP---AGFQHKSYQDHAGRAHD Mflv_1882|M.gilvum_PYR-GCK AIAAALADAAHNRATARVLGAVPGGWRNLP---SAFQVKAFRDATGETQE MSMEG_5493|M.smegmatis_MC2_155 AIAATLADAAHNRSAAEAFLPAPSGWRNLA---SGYQQRRYHDASGEEVE MAB_1071c|M.abscessus_ATCC_199 ALAAALADAAANRAAAVACAAVPSGWRNLRGPSSGFQTKEFVAG-DSTVR TH_3286|M.thermoresistible__bu AYHWLQRWAD----AADDLWSQPSGWRVGAQAATSYR-LEAGDRTDHVRL MLBr_00726|M.leprae_Br4923 WIETEWNNTI----------------------------EPFIDNQPLDEE : Mb0998c|M.bovis_AF2122/97 VEYRFTRTGLALPGD-----PVVQLVSADVDQVVLA-QDGVAHGFTVARH Rv0973c|M.tuberculosis_H37Rv VEYRFTRTGLALPGD-----PVVQLVSADVDQVVLA-QDGVAHGFTVARH MMAR_4534|M.marinum_M IEYRFTRTGLEIAGD-----DSVRLVSATPNEVVLAGENGVARRFTVASY MUL_4706|M.ulcerans_Agy99 IEYRFTRTGLQIAGD-----DSVRLVLATPNEVVLAGENGVARRFTVASY MAV_1089|M.avium_104 VQYRFTRTGLVLPDD-----PSVQLVSATADDVVLR-TDGVEHNFSVRRY Mvan_4849|M.vanbaalenii_PYR-1 VRYRFTRDGVMIDGH-----DDVSVVSAGQRQVVLT-VSGVDRPFDVTRY Mflv_1882|M.gilvum_PYR-GCK VRYRFTRAGLTLDGH-----DDVELVSATSHHVVLS-VAGVDRPFDVHRY MSMEG_5493|M.smegmatis_MC2_155 VRYRFARDGLRLPDD-----ENVALVSATPARVVLG-LDGVEYTFDVARH MAB_1071c|M.abscessus_ATCC_199 VRYRLTRTGLELDGASDTAWPTIELVSATPEHVALV-IDGVRRGFDVANY TH_3286|M.thermoresistible__bu TGHPYDATVAIEDGD------PRPLTAALTGSRLTVTVDGLRTDYTVAAA MLBr_00726|M.leprae_Br4923 DTRPQQTVIVEVDGR--------RLEVSLPADLALANPAGCN-------- . : : * Mb0998c|M.bovis_AF2122/97 G---PDVYVDSARGPVHLVALSRFPEPSSAVEQG--SLVAPMPGNVIRIG Rv0973c|M.tuberculosis_H37Rv G---PDVYVDSARGPVHLVALSRFPEPSSAVEQG--SLVAPMPGNVIRIG MMAR_4534|M.marinum_M G---QDVFVDSPSGPVHLVALPRFPEPGSAVEQG--SLVAPMPGNVIRLG MUL_4706|M.ulcerans_Agy99 G---QDVFVDSPSGPVHLVALPRFPEPGSAVEQG--SLVAPMPGNVIRLG MAV_1089|M.avium_104 HGADADVYVDSVRGPVHLTVLPRFPEPGSSVEKG--SLVAPMPGNVIRLG Mvan_4849|M.vanbaalenii_PYR-1 GD---SVFVDSPCGCTHFVALPRFPDPAAALAHG--SLLAPMPGSVLRVG Mflv_1882|M.gilvum_PYR-GCK GA---DVHVDSPGGSVHLVALSRFPDPDAAPAHG--SLLAPMPGSVLRVA MSMEG_5493|M.smegmatis_MC2_155 GDDVFDVFVDSPLGPVRFTAMPRFPDPGDAVAHG--SLLAPMPGTVVRVG MAB_1071c|M.abscessus_ATCC_199 G---DTVDIDSPLGPVALTVVPRFTDPSTEVAAG--SLIAPMPGVVLRLG TH_3286|M.thermoresistible__bu DG---RLWLAAAGRAVAVSEVREAPVRPDDEHRGDAELVSPMPGSVVALG MLBr_00726|M.leprae_Br4923 -----------PAGVIRKKPKPRKRGGHTGAATSGDAVTAPMQGTVVKVA . . : :** * *: :. Mb0998c|M.bovis_AF2122/97 AEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAIL Rv0973c|M.tuberculosis_H37Rv AEVGDTVTAGQPLIWLEAMKMEHTIAAPADGVLTHVSVNTGQQVEVGAIL MMAR_4534|M.marinum_M ADVGDAVTAGQPLIWLEAMKMEHTISAPTDGVLTQLNVQTGQQVDVGAVL MUL_4706|M.ulcerans_Agy99 ADVGDTVTAGQPLIWLEAMKMEHTISAPTDGVLTQLNVQTGQQVDVGAVL MAV_1089|M.avium_104 AAIGDTVTAGQSLIWLEAMKMEHTIAAPVDGVLAELNVKTGQQVEVGAVL Mvan_4849|M.vanbaalenii_PYR-1 AAPGDTVTAGQPLLWLEAMKMEHTITAPTDGVLVELNVEPGRQVEVGAVL Mflv_1882|M.gilvum_PYR-GCK AAQGDTVTAGQPLLWLEAMKMEHTITAPADGVLVALNVVAGQQVEVGAVL MSMEG_5493|M.smegmatis_MC2_155 ATVGAKVSAGQPLVWLEAMKMEHTVAAPSDGVLTELNVEPGRQVDVGEVL MAB_1071c|M.abscessus_ATCC_199 AAVGDAVTAGTPIVWLEAMKMEHTIVAPADGVVEILNVEPGQQVELGTVL TH_3286|M.thermoresistible__bu VSDGDAVDAGTLVVTVEAMKMEHPLTAPVAGVVELL-VAVGDQVKVGQPL MLBr_00726|M.leprae_Br4923 VAEGQTVMTGDLVVVLEAMKMENPVTAHKDGIITGLAVEAGTAITQGTVL . * * :* :: :******:.: * *:: : * * : * * Mb0998c|M.bovis_AF2122/97 ARVEAPQNGPAEGDSP Rv0973c|M.tuberculosis_H37Rv ARVEAPQNGPAEGDSP MMAR_4534|M.marinum_M ARVEAP---EAEGDS- MUL_4706|M.ulcerans_Agy99 ARVEAP---EAEGDS- MAV_1089|M.avium_104 ARVEAP---QSEGDAQ Mvan_4849|M.vanbaalenii_PYR-1 ARVESQEG--DPR--- Mflv_1882|M.gilvum_PYR-GCK ARVDTGDSGEESR--- MSMEG_5493|M.smegmatis_MC2_155 ARVEDPEG--EQR--- MAB_1071c|M.abscessus_ATCC_199 AQLAAEATTEGEPA-- TH_3286|M.thermoresistible__bu ARITTE----QED--- MLBr_00726|M.leprae_Br4923 AEIK------------ *.: