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DSPVDYAGPAACGGPFARLTLNSPHNRNALSSTLVSQLHQGLSAAEADPAVRLVVLGHTGGTFCAGADLS EAGGGGGDPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGGFGLVGACDMVVAGPESTFALTEAR IGVAPAIISLTLLPKLSPRAAARYYLTGEKFGAREAADIGLITMAADDVDAAVAALVADVGRGSPQGLAA SKALTTAAVLEGFDRDAERLTEESARLFVSDEAREGMLAFLQKRPPRWVQPATMRAAD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0971c | echA7 | - | 100% (269) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv2486 | echA14 | 7e-24 | 34.30% (207) | enoyl-CoA hydratase |
| M. tuberculosis H37Rv | Rv0222 | echA1 | 1e-22 | 29.88% (251) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0996c | echA7 | 1e-150 | 100.00% (269) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_1880 | - | 3e-97 | 72.65% (245) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_02118 | echA6 | 8e-20 | 31.20% (250) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_1069c | - | 2e-87 | 68.95% (248) | enoyl-CoA hydratase |
| M. marinum M | MMAR_4536 | echA7 | 1e-114 | 82.56% (258) | enoyl-CoA hydratase EchA7 |
| M. avium 104 | MAV_1087 | - | 1e-116 | 82.38% (261) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_5495 | - | 1e-99 | 74.29% (245) | enoyl-CoA hydratase |
| M. thermoresistible (build 8) | TH_3726 | - | 2e-31 | 38.04% (255) | PUTATIVE probable enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_4708 | echA7 | 1e-113 | 81.78% (258) | enoyl-CoA hydratase |
| M. vanbaalenii PYR-1 | Mvan_4851 | - | 1e-96 | 71.95% (246) | enoyl-CoA hydratase |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0971c|M.tuberculosis_H37Rv ------------------MDSPVDYAGPAACGGPFARLTLNSPHNRNALS
Mb0996c|M.bovis_AF2122/97 ------------------MDSPVDYAGPAACGGPFARLTLNSPHNRNALS
MAV_1087|M.avium_104 ------------------MDALVDYAGPAATGGPVARLTLNSPHNRNALS
MMAR_4536|M.marinum_M -----------------MADRLVEYAR----DGVVARLTLNSPHNRNALS
MUL_4708|M.ulcerans_Agy99 -----------------MADRLVEYAR----DGVVARLTLNSPHNRNALS
Mflv_1880|M.gilvum_PYR-GCK ------------------MSSLVRYDR----DGAVARLTLDSPHNRNALS
Mvan_4851|M.vanbaalenii_PYR-1 MGVPPACGGRSREEATVLMSTLVTYER----DGAVARLTLDSPHNRNALS
MSMEG_5495|M.smegmatis_MC2_155 ------------------MDTLVRYEV----DGAVARLTLDSPHNRNALS
MAB_1069c|M.abscessus_ATCC_199 -----------------MSDTLVQYEV----EGRAARLTLDSPHNRNALS
TH_3726|M.thermoresistible__bu -----------------MTTSIESPVILSTGEDGIARLRLNRPEASNGLT
MLBr_02118|M.leprae_Br4923 ------------------MIGITQAEG-------VMTIELQRPERRNALN
: *: *. *.*.
Rv0971c|M.tuberculosis_H37Rv STLVSQLHQGLSAAE---ADPAVRLVVLGHTGGTFCAGADLSEAGGGGG-
Mb0996c|M.bovis_AF2122/97 STLVSQLHQGLSAAE---ADPAVRLVVLGHTGGTFCAGADLSEAGGGGG-
MAV_1087|M.avium_104 TALVSQLHQGLRDAS---SDPAVRVVVLAHTGGTFCAGADLSEAGSGGSP
MMAR_4536|M.marinum_M TTLVTQLHEGLRDAA---ADPGVRVVVLGHTGGTFCAGADLTEAGSGDP-
MUL_4708|M.ulcerans_Agy99 TTLVTQLHEGLRDAA---ADPGVRVVVLGHTGGTFCTGADLSEAGSGDP-
Mflv_1880|M.gilvum_PYR-GCK TALVAQLHDGLTRAS---TETGVRAVVLTHTGGTFCAGADLSESPASGGD
Mvan_4851|M.vanbaalenii_PYR-1 TALVEQLHDGLTRAS---SEPRVRTVVLGHTGRTFCAGADLSE--AAGRD
MSMEG_5495|M.smegmatis_MC2_155 TALVEQLHEGFARAA---GQSGVRVVVLGHTGGTFCAGADLSE--AAGRD
MAB_1069c|M.abscessus_ATCC_199 SGLVRQLREGLQRAA---ADQTVRAVVLTHTGNTFCAGADLSEASEGSPQ
TH_3726|M.thermoresistible__bu VELLKALHEAVLACH---ADPAVKIVLLSGEGRNFCAGGDVKTFESKGES
MLBr_02118|M.leprae_Br4923 SQLIEKLREAVQKASSADSEVSTRVIVLTGQGTVFCAGADLSG-------
*: *::.. . : .: ::* * **:*.*:.
Rv0971c|M.tuberculosis_H37Rv -DPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGG-FGLVGACDM
Mb0996c|M.bovis_AF2122/97 -DPYRMAVARAREMTALLRAIVESPLPVVGAINGHVRAGG-FGLVGACDM
MAV_1087|M.avium_104 SSAYDMAVERAREMAALMRAIVESRLPVIAAIDGHVRAGG-FGLVGACDI
MMAR_4536|M.marinum_M ---YDLAVARAREMTTVLRAIVESPRPVIGAINGHVRAGG-FGLVGACDI
MUL_4708|M.ulcerans_Agy99 ---YDLAVARAREMTTVLRAIVESPRPVIGAINGHVRAGG-FGLVSACDI
Mflv_1880|M.gilvum_PYR-GCK --PAEAALGRAREMTTLLRRILEVPLPVIAAIDGHVRAGG-LGLVGACDI
Mvan_4851|M.vanbaalenii_PYR-1 --PSDLAVDRAREMTRLLRRILELPLPVIAAVDGHVRAGG-LGLVGACDI
MSMEG_5495|M.smegmatis_MC2_155 --PADIAVDRAREMTTLLRAILELRLPVIGAIDGHVRAGG-LGLVGACDV
MAB_1069c|M.abscessus_ATCC_199 ----DIAKDRAGQLTALLRDILELPLPVIIAVNGHVRAGG-FGLVGAADI
TH_3726|M.thermoresistible__bu --LPEYLREATAWLQLATAALIQLRVPVVTAVQGYVAGGGGLGLVCASDF
MLBr_02118|M.leprae_Br4923 ---DAFAADYPDRLIELHRVMDAVPMPVIGAINGPAIGAG-LQLAMQCDL
. : : **: *::* . ..* : *. .*.
Rv0971c|M.tuberculosis_H37Rv VVAGPESTFALTEARIGVAP-AIISLTLLPKLSPRAAARYYLTGEKFGAR
Mb0996c|M.bovis_AF2122/97 VVAGPESTFALTEARIGVAP-AIISLTLLPKLSPRAAARYYLTGEKFGAR
MAV_1087|M.avium_104 AVAGPRSSFALTEARIGVAP-AIISLTLLPKLSARAAARYYLTGEKFDAR
MMAR_4536|M.marinum_M VVAGPACTFALTEARIGVAP-AIISLTLLPKLSARAAARYYLTGAKFGAD
MUL_4708|M.ulcerans_Agy99 VVAGPACTFALTEARIGVAP-AIISLTLLPKLSARAAARYYLTGAKFGAD
Mflv_1880|M.gilvum_PYR-GCK VVAGRASTFALTEARIGVAP-SIISLTVLPKMSLRSAGRYFVTGEKFGAE
Mvan_4851|M.vanbaalenii_PYR-1 AVAGDSSTFALTEARIGVAP-SIISLTLLPKMTARAAGRYFVTGEKFGAA
MSMEG_5495|M.smegmatis_MC2_155 VVAGPGSTFALTEARIGVAP-SIISLTLLPKMTPRSAGRYFLTGERFGAE
MAB_1069c|M.abscessus_ATCC_199 AVAGPDSTFALTEARIGVAP-SIISLTLLPRLTSRAAGRYFVTGEKFDAR
TH_3726|M.thermoresistible__bu VIAARSAKFFSGAVRVGMAPDGGASVTLTQLVGLRQALRILLANPTLSAE
MLBr_02118|M.leprae_Br4923 RVVAPDAYFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLTAEKLTAD
:.. . * : *:* : : * :: : *
Rv0971c|M.tuberculosis_H37Rv EAADIGLITMAAD---DVDAAVAALVADVGRGSPQGLAASKALTTAAVLE
Mb0996c|M.bovis_AF2122/97 EAADIGLITMAAD---DVDAAVAALVADVGRGSPQGLAASKALTTAAVLE
MAV_1087|M.avium_104 RAEEIGLITMAAE---DLDAAIDQLVTDVGRGSPQGLAASKALTTAAVLE
MMAR_4536|M.marinum_M EAAEMGLVTIAAD---DVEAAVAALIADVGRGSPQGLAASKALTTAAVLA
MUL_4708|M.ulcerans_Agy99 EAAEMGLVTIAAD---DMEAAVAALIADVGRGSPQGLAASKALTTAAVLA
Mflv_1880|M.gilvum_PYR-GCK EAAAAGLVTLAAD---DVAAAVSELTSAIAKGSPQGLAASKALTTAAVID
Mvan_4851|M.vanbaalenii_PYR-1 EAAAMGLVTVATD---DVPGTVADLTSAIAQGSPQGLAASKALTTAALID
MSMEG_5495|M.smegmatis_MC2_155 EAAAVGLVTVAAD---DVDTAVAALAGEIAKGSPQGLATSKALTTAAILR
MAB_1069c|M.abscessus_ATCC_199 VAAEIGLVTQSVDSAEAVEAAVTSLVDDIALGSPQGLAESKRLTTAPILA
TH_3726|M.thermoresistible__bu EAAGIGLITEVVDD-VELTARAEALAAELTALPPLALSATKRLVWSGVGQ
MLBr_02118|M.leprae_Br4923 IALQTGMANRIGA-----LADAQAWAAEVTGLAPLAIQHAKRVLND--DG
* *: . : .* .: :* :
Rv0971c|M.tuberculosis_H37Rv GFDRDAERLTEESARLFVSDEAREGMLAFLQKRPPRWVQPATMRAAD
Mb0996c|M.bovis_AF2122/97 GFDRDAERLTEESARLFVSDEAREGMLAFLQKRPPRWVQPATMRAAD
MAV_1087|M.avium_104 RFDRDAERLAEESARLFVSDEAREGMLAFLEKRSPNWTS--------
MMAR_4536|M.marinum_M GFDRDAERLTEESARLFVSEEAREGMLAFLQKRQPSWASD-------
MUL_4708|M.ulcerans_Agy99 GFDRDAERLTEESARLFVSEEAREGMLAFLQKRQPSWASD-------
Mflv_1880|M.gilvum_PYR-GCK DFDRRAEKLTRESAELFVSDEAREGMLAFLQKRAPSWAG--------
Mvan_4851|M.vanbaalenii_PYR-1 DFERRAEKLTQESARLFVSEEAREGMLAFLEKRPPRWVG--------
MSMEG_5495|M.smegmatis_MC2_155 DFDEHAEELTQQSARLFVSDEAREGMLAFLQKRSPNWAD--------
MAB_1069c|M.abscessus_ATCC_199 DFDARAVELTETSARLFVSPEAQEGMLAFLQKRPPAWQV--------
TH_3726|M.thermoresistible__bu SVAERLAEEARTVSELSGTADSLEGLRAVIERRPPRFTGR-------
MLBr_02118|M.leprae_Br4923 SIEEAWPEHKKLFDKAWTSQDVIEAQVARVEKRPPKFQGA-------
. . . . : : *. * :::* * :