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DAAQVIEPAHAGQDVDEAAVAARELSGAERALVGDLVRQARAEGVALTGPDGLLKALTKTVLEAALQEEM TEHLGYDRHAAAGRGSGNSRNGSRNKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSL YAKGLTTGEIAAHFADVYGVSVSKDTISRITDRVIEEMQAWWSRPLEKVYAAVFIDAIMVKIRDGQVRNR PVYAAIGVDLDGHKDILGMWAGEGDGESAKFWLAVLTDLRNRGVKDIFFLVCDGLKGLPDSVSAAFPLAT VQTCIIHLIRNTFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAEKWGKPYPAITRLWDSAWEEFI PFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQSALKTLYLVTRSLDPKGTGQTKWAVRWKPA LNALAITFADRMPAAEER*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0920c | - | - | 100% (439) | PROBABLE TRANSPOSASE |
| M. tuberculosis H37Rv | Rv3640c | - | 1e-33 | 28.53% (347) | transposase |
| M. tuberculosis H37Rv | Rv3431c | - | 5e-29 | 30.50% (282) | hypothetical protein Rv3431c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0944c | - | 0.0 | 99.77% (439) | putative transposase |
| M. gilvum PYR-GCK | Mflv_3191 | - | 2e-30 | 27.19% (342) | transposase, mutator type |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_3254 | - | 1e-114 | 50.12% (405) | transposase, Mutator family protein |
| M. smegmatis MC2 155 | MSMEG_4154 | - | 2e-31 | 28.76% (299) | transposase, Mutator family protein |
| M. thermoresistible (build 8) | TH_3008 | - | 1e-88 | 41.61% (435) | PUTATIVE transposase, mutator type |
| M. ulcerans Agy99 | MUL_4727 | - | 1e-179 | 71.26% (435) | transposase for IS2606 |
| M. vanbaalenii PYR-1 | Mvan_5974 | - | 1e-115 | 50.48% (420) | transposase, mutator type |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0920c|M.tuberculosis_H37Rv MDAAQVIEPAHAGQDVDEA-AVAARELSG----AERALVGDLVRQARAEG
Mb0944c|M.bovis_AF2122/97 MDAAQVIEPAHAGQDVDEA-AVAARELSG----AERALVGDLVRQARAEG
MUL_4727|M.ulcerans_Agy99 MMTKTVVAVQPSQNHEDEAGAVAAIDVPSSRDVDELEVARELVRQAREAG
MAV_3254|M.avium_104 -----MSRSD---SSRDEAAKQLAQVLPP-------AALDALLADAEASG
Mvan_5974|M.vanbaalenii_PYR-1 -----MSRSE---SSADEAAAKLAQVLPA-------AAVDALLADAEATG
TH_3008|M.thermoresistible__bu -----MTMTDEKGTSSTTGNELVAQLQAS-------GALDELFAKIDSGE
Mflv_3191|M.gilvum_PYR-GCK ------------------------------------MTQDHSALLAQLDA
MSMEG_4154|M.smegmatis_MC2_155 ------------------------------------MTQDHSALLAQLDA
Rv0920c|M.tuberculosis_H37Rv VALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSR
Mb0944c|M.bovis_AF2122/97 VALTGPDGLLKALTKTVLEAALQEEMTEHLGYDRHAAAGRGSGNSRNGSR
MUL_4727|M.ulcerans_Agy99 VGLTGPGGLLKAMTKTVIETALDEELSEHLGYDRHDRAGYGSGNSRNGTR
MAV_3254|M.avium_104 TPIDGPDGLLAQITKSVLERALDVEIADHLGYEHGDPAGNGSGNSRNGHG
Mvan_5974|M.vanbaalenii_PYR-1 TPIDGPDGLLAQITKSVLERALDVEIADHLGYEHGDPAGNGSGNSRNGHG
TH_3008|M.thermoresistible__bu VEITGSDGLLPALLKTTLERGLQAELTGHLGYEKGEPAPAKRPNARNGTT
Mflv_3191|M.gilvum_PYR-GCK LRSADAGAVFAELIRAGLQQLIEAEATAAIGAGRYQRT-DGRMVHRNGHR
MSMEG_4154|M.smegmatis_MC2_155 LKSADAGAVFAELIRAGLQALIEAEATEVIGAGRYQRT-DGRATHRNGHR
....:: : :: :: :: * : :* : : ***
Rv0920c|M.tuberculosis_H37Rv NKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKG
Mb0944c|M.bovis_AF2122/97 NKKVITDACGQVEIAVPRDRNGTFEPVIVGKRKRRVTDVDRVVLSLYAKG
MUL_4727|M.ulcerans_Agy99 SKTVLTDACGSIEIDVPRDRAGTFEPKIVEKRQRRLTDVDEVVLSLYARG
MAV_3254|M.avium_104 RKTVLT-TAGPVDLEVPRDRNGTFDPVIVPKRKRRLGQVEDMILSLYARG
Mvan_5974|M.vanbaalenii_PYR-1 RKAVLT-TAGPVDLEVPRDRNGTFDPQIVPKRKRRLGQVEDMILSLYARG
TH_3008|M.thermoresistible__bu SKTIES-EVGSFTIDVPRDRAGTFTPRLIRKGQRRLDGLDDMIISLYAGG
Mflv_3191|M.gilvum_PYR-GCK PKTVST-TSGDIEVQIPKLRAGSFFPSLLERRRRIDKALHAVIMEAYVHG
MSMEG_4154|M.smegmatis_MC2_155 PKTVST-TAGDVEVQIPKLRAGSFFPSLLERRRRIDRALHAVIMEAYVHG
* : : * . : :*: * *:* * :: : :* :. :::. *. *
Rv0920c|M.tuberculosis_H37Rv LTTGEIAAHFADV-YGVSVSKDTISRITDRVIEEMQAWWSRPLEK-VYAA
Mb0944c|M.bovis_AF2122/97 LTTGEIAAHFADV-YGVSVSKDTISRITDRVIEEMQAWWSRPLEK-VYAA
MUL_4727|M.ulcerans_Agy99 LTTGEISAHFAHI-YDAAVSKDTVSRITDRVLEEMTAWHTRPLER-VYAA
MAV_3254|M.avium_104 MSTRDITEHLAEV-YGASVSAATVSRVTEVVADEIAAWQSRPVDP-VYPI
Mvan_5974|M.vanbaalenii_PYR-1 MSTRDITEHLGEV-YGATVSAATISRVTDVVADEIAAWQSRPVDP-VYPI
TH_3008|M.thermoresistible__bu MTVREIEHHLATT-IGVELSAGTISAITDAVADAVLQWQNRPLEE-FYPV
Mflv_3191|M.gilvum_PYR-GCK VSTRSVDDLVAAMGVESGVSKSEVSRICAGLDIEIEAFRTRSLAHTEFPY
MSMEG_4154|M.smegmatis_MC2_155 VSTRSVDDLVAALGVGSGVSKSEVSRICAGLDKEIDAFRTRSLNHTSFPY
::. .: .. :* :* : : : : .*.: :.
Rv0920c|M.tuberculosis_H37Rv VFIDAIMVKIRDG-QVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKF
Mb0944c|M.bovis_AF2122/97 VFIDAIMVKIRDG-QVRNRPVYAAIGVDLDGHKDILGMWAGEGDGESAKF
MUL_4727|M.ulcerans_Agy99 VFIDALHVKIRDG-QVGPRPVYAAVGVDLAGHRDVLGMWAGEGDGESAKY
MAV_3254|M.avium_104 LYIDAIRLKIRDGGVVSNKAAHVVIGVDVEGIKQVLGVWIQQTEG--AKF
Mvan_5974|M.vanbaalenii_PYR-1 LYIDAIRLKIRDGGVVANKAAHVVIGVDVDGIKQVLGVWIQQTEG--AKF
TH_3008|M.thermoresistible__bu IYLDAIRIKVRQDHRVVGRSAYIAVGVDLEGIKHVLGIWVQDTEG--ASF
Mflv_3191|M.gilvum_PYR-GCK IFCDATFCKVRVGAHVVSQALVVATGVSIDGTREVLGTAVGDSES--FEF
MSMEG_4154|M.smegmatis_MC2_155 VFCDATFCKVRIGAHVVSQALVVATGVSIDGTREVLGTAVGDSES--FEF
:: ** *:* . * :. . **.: * :.:** : :. .:
Rv0920c|M.tuberculosis_H37Rv WLAVLTDLRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRN
Mb0944c|M.bovis_AF2122/97 WLAVLTELRNRGVKDIFFLVCDGLKGLPDSVSAAFPLATVQTCIIHLIRN
MUL_4727|M.ulcerans_Agy99 WLAVLTELKNRGVADIFFLVCDGLKGLPDSVSAVFPDTVVQTCIIHLIRG
MAV_3254|M.avium_104 WHGVLTELRNRGCRDALFVCCDGLAGLPESIAAVWPQAVIQTCVVHLLRA
Mvan_5974|M.vanbaalenii_PYR-1 WHGVLTELRNRGCRDALFVCCDGLTGLPESITAVWPQAIIQTCVVHLLRA
TH_3008|M.thermoresistible__bu WAHVCADLANRGVRDVLIVCCDGLAGLPEAIEATWPDSMVQTCVVHLIRA
Mflv_3191|M.gilvum_PYR-GCK WREFLASLKARGLTGVHLVISDAHVGLKTAVAQQFTNSSWQRCRVHFMRN
MSMEG_4154|M.smegmatis_MC2_155 WREFLASLKARGLSGVHLVISDAHAGLKAAVAQQFTGSSWQRCRVHFMRN
* . :.* ** . :: .*. ** :: :. : * * :*::*
Rv0920c|M.tuberculosis_H37Rv TFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAE-KWGKPYPAITR
Mb0944c|M.bovis_AF2122/97 TFRYASRKYWDKISVDLKPIYTAASAAEARLRYEEFAE-KWGKPYPAITR
MUL_4727|M.ulcerans_Agy99 TFRYAGRQHHTAIARALKPIYTAVNAAAAAEALDAFDT-EWGHRYPAAIR
MAV_3254|M.avium_104 SMRYASYTDRKKMAAALRPIYTAATEQAAAVALEQFRT-EWKAKSPGAVA
Mvan_5974|M.vanbaalenii_PYR-1 SMRYASYTDRKKMAAALRPIYTAATEEAAKLALEEFRA-EWKTKSPGAVA
TH_3008|M.thermoresistible__bu SMRFVSYGDRKKVAAELKKIYTAPNEETALAALAEFEASAWGAKYPQTVA
Mflv_3191|M.gilvum_PYR-GCK LHTAVAAKHAPAVTAAVKTIFAHTDPVEVAAQWDRVAD-TLAPSFPKVAA
MSMEG_4154|M.smegmatis_MC2_155 LHGVVAAKHAPAVTAAVKTIFAHTDPVDVAAQWDQVAD-TLAASFPKVAA
.. :: :: *:: . . *
Rv0920c|M.tuberculosis_H37Rv LWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQ
Mb0944c|M.bovis_AF2122/97 LWDSAWEEFIPFLDYDVEIRRVPCSTNAIESLNARYRRAVRARGHFPNEQ
MUL_4727|M.ulcerans_Agy99 LWRNAWNEFIPFLDYDTEIRKVICSTNAIESLNARYRRAIRARGHFPTEQ
MAV_3254|M.avium_104 VWDRSWAEFVPFLAFPVEIRKIIYTTNAIESLNYQLRKVTKARGSFPSDA
Mvan_5974|M.vanbaalenii_PYR-1 VWDRAWAEFVPFLAFPVEIRKIIYTTNAIESLNYQLRKVTKARGSFPSDA
TH_3008|M.thermoresistible__bu TWTAAWERFTPFLQFPPMLRRVIYTTNSIESLNFQLRKVTKNRGHFPSTE
Mflv_3191|M.gilvum_PYR-GCK MMGEAKTDVLAFTAFPRAHWQKIWSNNPIERLNKEIKRRADVVEIFPNPA
MSMEG_4154|M.smegmatis_MC2_155 MMDEAKADVLAFTAFPRTHWQKIWSNNPIVIC-------SAAVSVFY---
: . .* : : :.*.* *
Rv0920c|M.tuberculosis_H37Rv SALKTLYLVTRSLD-----------------PKGTG---QTKWAVRWKPA
Mb0944c|M.bovis_AF2122/97 SALKTLYLVTRSLD-----------------PKGTG---QTKWAVRWKPA
MUL_4727|M.ulcerans_Agy99 SALKCLYLVTRSLD-----------------PTGTG---QKRWTMRWKPA
MAV_3254|M.avium_104 AAMKLLYLAIRNIN----------------QKRGSA---QGQGTYRWTEA
Mvan_5974|M.vanbaalenii_PYR-1 AALKLLYLAIRNIN----------------QKRGSN---PGSGTYRWTEA
TH_3008|M.thermoresistible__bu SAVKLLWLAICNIEDRRARERAAEKGKPAGQRRASGRLVEGQVTTNWKQA
Mflv_3191|M.gilvum_PYR-GCK AFLRLATAVVIEAHD---------------EWQVTRRYLSDISMDELRVV
MSMEG_4154|M.smegmatis_MC2_155 ---------VDHEGS---------------EWSVLR-SGCGYLQPSMKQI
Rv0920c|M.tuberculosis_H37Rv LNALAITFADRMPAAEER
Mb0944c|M.bovis_AF2122/97 LNALAITFADRMPAAEER
MUL_4727|M.ulcerans_Agy99 LNAFAITFADRMPGSETT
MAV_3254|M.avium_104 LNAFAIQFPDRLPL----
Mvan_5974|M.vanbaalenii_PYR-1 LNAFAIQFPDRLPL----
TH_3008|M.thermoresistible__bu LAQLAAAYPDRINPYL--
Mflv_3191|M.gilvum_PYR-GCK IEKKHAAAALAKQHQIT-
MSMEG_4154|M.smegmatis_MC2_155 LEGRCACCEGGFTALVA-
: