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TQDTSEADPLTSGSAADSVPVAAGCPVTSGGYDSVPQPLGPDSLTWKYFGQWTGLFQGPWAGSMQNMHPQ LGAAVKDHSIFFMERMPRLLRSIYPIGGVVFDGDRAPKTGAQVRDYHIGLTGVDDQGRRYSALNPDVFYW AHATFFKSTLLAAERFHGGLTEDQRRQLFDEHVTWYRMYGMSMRPVPKTWEDFQEYWDHMCTNVLENNWA TREVLDLSTMPKHPSLEWVPDWLWKQNLKVMQRFLLFMTVGLYDPPIRELMGFTWSPRQEWLHRRVGNML HLATRLLPDRVTMHPRKRSAMDRAFGRLPADAPLVETPARNLPPVEYRDNPHYYSPKV*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5083 | - | - | 100% (339) | hypothetical protein Mvan_5083 |
M. vanbaalenii PYR-1 | Mvan_3322 | - | 2e-88 | 52.51% (299) | hypothetical protein Mvan_3322 |
M. vanbaalenii PYR-1 | Mvan_0854 | - | 7e-41 | 37.92% (240) | hypothetical protein Mvan_0854 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0849 | - | 1e-144 | 68.18% (352) | hypothetical protein Mb0849 |
M. gilvum PYR-GCK | Mflv_1670 | - | 1e-178 | 84.66% (339) | hypothetical protein Mflv_1670 |
M. tuberculosis H37Rv | Rv0826 | - | 1e-145 | 68.47% (352) | hypothetical protein Rv0826 |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0757 | - | 1e-137 | 65.43% (324) | hypothetical protein MAB_0757 |
M. marinum M | MMAR_4854 | - | 1e-142 | 66.19% (352) | hypothetical protein MMAR_4854 |
M. avium 104 | MAV_0774 | - | 1e-139 | 64.04% (356) | hypothetical protein MAV_0774 |
M. smegmatis MC2 155 | MSMEG_5767 | - | 1e-157 | 74.04% (339) | hypothetical protein MSMEG_5767 |
M. thermoresistible (build 8) | TH_1574 | - | 1e-150 | 75.32% (312) | CONSERVED HYPOTHETICAL PROTEIN |
M. ulcerans Agy99 | MUL_0447 | - | 1e-142 | 66.19% (352) | hypothetical protein MUL_0447 |
CLUSTAL 2.0.9 multiple sequence alignment Mb0849|M.bovis_AF2122/97 MTQDTSATCPLTSTVQDSSP----VAGQLGRPIGF-RGLAGGCPVSPLGY Rv0826|M.tuberculosis_H37Rv MTQDTSATCPLTSTVQDSSP----VAGQLGRPIGF-RGLAGGCPVSPLGY MMAR_4854|M.marinum_M MTQDTSAACPLTSAEPKSSTN---SAGQVAAPGDS-QPAATGCPVSPLGY MUL_0447|M.ulcerans_Agy99 MTQDTSAACPLTSAEPKSSTN---SAGQVAAPGDS-QPAATGCPVSPLGY MAV_0774|M.avium_104 MTQDTSASRPLTSDVTGSDAAGRTEQSISARPADAGAALAVGCPVSPLGY MAB_0757|M.abscessus_ATCC_1997 MVNDMSELAKVQPAAESG-------------------AFVSGCPVSHGTG MSMEG_5767|M.smegmatis_MC2_155 MTQDTSETCPVTSGSARP---------------------AAGCPAALGGY TH_1574|M.thermoresistible__bu --------------------------------------------VSAGGY Mvan_5083|M.vanbaalenii_PYR-1 MTQDTSEADPLTSGSAADSV-----------------PVAAGCPVTSGGY Mflv_1670|M.gilvum_PYR-GCK MTQDTSAAGPVTSDSGEASG-----------------AVAAGCPISGGGY : Mb0849|M.bovis_AF2122/97 ESPPLPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF Rv0826|M.tuberculosis_H37Rv ESPPLPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF MMAR_4854|M.marinum_M EAPPIPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF MUL_0447|M.ulcerans_Agy99 EAPPIPLGPDSLTWRYFGDWRGMLQGPWAGSMQNMHPQLGAAVEDHSTFF MAV_0774|M.avium_104 EAPPAPLGPDSLTWKYFGDWRGMLQGPWAGSMQNMHPQLGAAVLDHSTFF MAB_0757|M.abscessus_ATCC_1997 KSMPVPLGPESLTWKYFGDWRGMLQGPYAGSMQNMHPQLGAAVEQHSQFF MSMEG_5767|M.smegmatis_MC2_155 EAPPEVLGPDSLTWKIFGDWRGLLQGPWAGSMQNMHPQLGAAVEEHSIFF TH_1574|M.thermoresistible__bu DAPPEVLGPDSLTWKIFGDWRGLLQGPWAGSMQNMHPQLGAAVKDHSIFF Mvan_5083|M.vanbaalenii_PYR-1 DSVPQPLGPDSLTWKYFGQWTGLFQGPWAGSMQNMHPQLGAAVKDHSIFF Mflv_1670|M.gilvum_PYR-GCK DALPEPLGPDSLTWKYFGQWTGLFQGTWAGSMQNMHPQLGAAVKDHSIFF .: * ***:****: **:* *::**.:*************** :** ** Mb0849|M.bovis_AF2122/97 RGRWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAGRRYHA Rv0826|M.tuberculosis_H37Rv RERWPRLLRSLYPIGGVVFDGDRAPVTGVQVRDYHITIKGVDGAGRRYHA MMAR_4854|M.marinum_M RERWPRLLRSLYPIGGVVFDGDRAPVTGAEVRDYHVNIKGVDAAGRRYHA MUL_0447|M.ulcerans_Agy99 RERWPRLLRSLYPIGGVVFDGDRAPVTGAEVRDYHVNIKGVDAAGRRYHA MAV_0774|M.avium_104 RERWPRLLRSLYPIGGVVFDGDRAPITGAEVRDYHTDIKGVDEQGRRYHA MAB_0757|M.abscessus_ATCC_1997 RERWQRLLRSLYPIGGVVFDGDRAPMTGAEVRDYHVNIKGVDDQGRRYSA MSMEG_5767|M.smegmatis_MC2_155 RERIPRLLRSLYPIGGVVFDGDRAPQTGAQVRDYHIGIKGVDSQGRRYSA TH_1574|M.thermoresistible__bu TERIPRLLRSLYPIGGVVFDGDRAPRTGAEVRDYHIGIKGVDEQGRRYSA Mvan_5083|M.vanbaalenii_PYR-1 MERMPRLLRSIYPIGGVVFDGDRAPKTGAQVRDYHIGLTGVDDQGRRYSA Mflv_1670|M.gilvum_PYR-GCK MERIPRLLRSIYPIGGVVFDGDRAPKTGAQVRDYHIGLNGVDDQGRRYSA * *****:************** **.:***** :.*** **** * Mb0849|M.bovis_AF2122/97 LNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMS Rv0826|M.tuberculosis_H37Rv LNPDVFYWAHATFFVGTLHVAERFCGGLTEAQRRQLFDEHVQWYRMYGMS MMAR_4854|M.marinum_M LNPDVFYWAHATFFVGTIHVAERFCGGLTEAQKRQLFDEHVQWYRMYGMS MUL_0447|M.ulcerans_Agy99 LNPDVFYWAHATFFVGTIHVAERFCGGLTEAQKRQLFDEHVQWYRMYGMS MAV_0774|M.avium_104 LNPDVFYWAHSTFFVGTIHVAERFCGGITEEQKRQLFDEHVQWYRMYGMS MAB_0757|M.abscessus_ATCC_1997 LNPDVFYWAHATFFMGTIIVAERFCGGITEAEKRQLFDEHITWYQMYGMS MSMEG_5767|M.smegmatis_MC2_155 LNPDVFYWAHSTFFMGTILTAERFGGGLTEDQKRQLFDEHIVWYRQYGMS TH_1574|M.thermoresistible__bu LNPDVFYWAHSTFFMGTILTAERFGDGLTEDQKRRLFDEHITWYRMYGMS Mvan_5083|M.vanbaalenii_PYR-1 LNPDVFYWAHATFFKSTLLAAERFHGGLTEDQRRQLFDEHVTWYRMYGMS Mflv_1670|M.gilvum_PYR-GCK LNPDVFYWAHATFFKSTLLAAEKFGGGLTEADKRQLFDEHVTWYRMYGMS **********:*** .*: .**:* .*:** ::*:*****: **: **** Mb0849|M.bovis_AF2122/97 MRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDW Rv0826|M.tuberculosis_H37Rv MRPVPATWEEFQDYWDHMCRNVLENNFAARAVLDLTELPKPPFAQRVPDW MMAR_4854|M.marinum_M MRPVPASWEEFQVYWDHMCCNVLENNFAARAVLDLTELPKPPFAQRVPDR MUL_0447|M.ulcerans_Agy99 MRPVPASWEEFQVYWDHMCCNVLENNFAARAVLDLTELPKPPFAQRVPDR MAV_0774|M.avium_104 MRPVPKSWEEFQEYWDHMCRNVLENNEAARAVLDLTELPRPPFAQRIPNR MAB_0757|M.abscessus_ATCC_1997 MRPVPKSWEEFQEYWDHMCTNVLEDNKATRDVLDLTTLAVPPFAPWIPKW MSMEG_5767|M.smegmatis_MC2_155 MRPVPKTWEEFQEYWDHICRNVLENNYAAREVLDLSTMPKHPSLEWIPDW TH_1574|M.thermoresistible__bu MRPVPGSWEEFQQYWDHMCRNVLENTWAARQVLDLSTMPKHPSLQWIPDW Mvan_5083|M.vanbaalenii_PYR-1 MRPVPKTWEDFQEYWDHMCTNVLENNWATREVLDLSTMPKHPSLEWVPDW Mflv_1670|M.gilvum_PYR-GCK MRPVPKTWEEFQEYWDHMCTDVLENNWAAREVMDLSTMPKHPSLEWIPDP ***** :**:** ****:* :***:. *:* *:**: :. * :*. Mb0849|M.bovis_AF2122/97 LWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLRRDEWLHRRFGDIVQL Rv0826|M.tuberculosis_H37Rv LWAAPRKLLARFFVWLTVGLYDPPVRELMGYRWLRRDEWLHRRFGDIVRL MMAR_4854|M.marinum_M LWALQRKLLAPFFVWVTVGLYDPPVRTLMGYQWSRRDEWLHRRFGDLVRL MUL_0447|M.ulcerans_Agy99 LWALQRKLLVPFFVWVTVGLYDPPVRTLMGYQWSRRDEWLHRRFGDLVRL MAV_0774|M.avium_104 LWAAQRKLLAPFFVWVTVGLYDPPVRELMGYRWSARDEWLHRRFGDLVRI MAB_0757|M.abscessus_ATCC_1997 LWALQRRMLSPFFVWFTVGLYDPPVRKRLGYTWSDRDEWLHRSFGRLVNV MSMEG_5767|M.smegmatis_MC2_155 LWKLNLKILGPFAVWVTVGLYDPPVRELMGYTWSDRDEKLHRLFGKAVHY TH_1574|M.thermoresistible__bu LWKLQLKVLGPFAVWVTVGLYDPPVRELMGYTWSERDERLHRLFGRAVNL Mvan_5083|M.vanbaalenii_PYR-1 LWKQNLKVMQRFLLFMTVGLYDPPIRELMGFTWSPRQEWLHRRVGNMLHL Mflv_1670|M.gilvum_PYR-GCK LWKLNLAVMQRFLTFMTVALYDPPVRELMGYTWSPRQEFLHRRFCDVVTL ** :: * :.**.*****:* :*: * *:* *** . : Mb0849|M.bovis_AF2122/97 VFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPT Rv0826|M.tuberculosis_H37Rv VFALVPFRFRKHPRARAGWDRATGRIPADAPLVQTPARNLPPPDERDNPT MMAR_4854|M.marinum_M IFALVPSRMRKHPRGRAGWDRAKGRIPADAPLVQTPARNLPPLDERDNPM MUL_0447|M.ulcerans_Agy99 IFALVPRRMRKHPRGRAGWDRAMGRIPADAPLVQTPARNLPPLDERDNPM MAV_0774|M.avium_104 VFALVPSRFRKHPRARAGLDRASGRIPLDAPLVQTPARNLPPEDERGNPK MAB_0757|M.abscessus_ATCC_1997 VFRFVPERFRRHPRARAGWDRALGRIPADAPLPQTPDRNLPPLDTWGSPN MSMEG_5767|M.smegmatis_MC2_155 TFKMLPERRRRHPRARAGWDRAQGRIPADAPLVETPARNLPPLDARDSPW TH_1574|M.thermoresistible__bu AFKLLPKRRRMHPRARAGWDRATGRIPADAPLVHTPARNLPPVEHRGKPI Mvan_5083|M.vanbaalenii_PYR-1 ATRLLPDRVTMHPRKRSAMDRAFGRLPADAPLVETPARNLPPVEYRDNPH Mflv_1670|M.gilvum_PYR-GCK ATKVLPKRWLMHPRKRSAWDRATGRLPADSALVETPARNLPPLEYRDNPH .:* * *** *:. *** **:* *:.* .** ***** : ..* Mb0849|M.bovis_AF2122/97 HYCPKV-- Rv0826|M.tuberculosis_H37Rv HYCPKV-- MMAR_4854|M.marinum_M HYCPEV-- MUL_0447|M.ulcerans_Agy99 HYCPEV-- MAV_0774|M.avium_104 HYCPMVS- MAB_0757|M.abscessus_ATCC_1997 HYNPKVS- MSMEG_5767|M.smegmatis_MC2_155 HYCPAVTK TH_1574|M.thermoresistible__bu HYCPDV-- Mvan_5083|M.vanbaalenii_PYR-1 YYSPKV-- Mflv_1670|M.gilvum_PYR-GCK YYSPKV-- :* * *