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M. tuberculosis H37Rv Rv0734 (mapA)

annotation: methionine aminopeptidase
coordinates: 826670 - 827470
length: 266

MRPLARLRGRRVVPQRSAGELDAMAAAGAVVAAALRAIRAAAAPGTSSLSLDEIAESVIRESGATPSFLG
YHGYPASICASINDRVVHGIPSTAEVLAPGDLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEATRE
SLQAGIAAMVVGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGRQMHMDPFLPNEGAPGRGPLL
AAGSVLAIEPMLTLGTTKTVVLDDKWTVTTADGSRAAHWEHTVAVTDDGPRILTLG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0734mapA-100% (266)methionine aminopeptidase
M. tuberculosis H37RvRv2861cmapB3e-4036.89% (244) methionine aminopeptidase
M. tuberculosis H37RvRv2535cpepQ6e-1731.47% (232) cytoplasmic peptidase PepQ

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0755mapA1e-150100.00% (266) methionine aminopeptidase
M. gilvum PYR-GCKMflv_5020-1e-12179.17% (264) methionine aminopeptidase
M. leprae Br4923MLBr_01831mapA1e-12883.97% (262) methionine aminopeptidase
M. abscessus ATCC 19977MAB_3782c-1e-11175.00% (256) methionine aminopeptidase
M. marinum MMMAR_1072mapA1e-13185.71% (266) methionine aminopeptidase, MapA
M. avium 104MAV_4432map1e-13186.47% (266) methionine aminopeptidase
M. smegmatis MC2 155MSMEG_1485map1e-11778.54% (261) methionine aminopeptidase
M. thermoresistible (build 8)TH_3403-1e-11880.38% (260) PUTATIVE methionine aminopeptidase, type I
M. ulcerans Agy99MUL_0830mapA1e-13185.71% (266) methionine aminopeptidase
M. vanbaalenii PYR-1Mvan_1349-1e-12480.75% (265) methionine aminopeptidase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_5020|M.gilvum_PYR-GCK          MVSLPGLRSRKVVPQRTAGELDAMAAAGALVAAALKAVQAEAAPGKSTLD
Mvan_1349|M.vanbaalenii_PYR-1       MVSLPGLRSRKVVPQRSAGELDAMAAAGALVAAALKAVRAAAAPGVSTLE
MSMEG_1485|M.smegmatis_MC2_155      MINLRGRRKPKVVTQRTSAELDAMAVAGALVASALRAVKAAAAPGVSTLE
TH_3403|M.thermoresistible__bu      LVGLRLRNR-KVVAQRSAGELDAMAAAGALVAEALRAVQAAAAPGVSTKH
Rv0734|M.tuberculosis_H37Rv         MRPLARLRGRRVVPQRSAGELDAMAAAGAVVAAALRAIRAAAAPGTSSLS
Mb0755|M.bovis_AF2122/97            MRPLARLRGRRVVPQRSAGELDAMAAAGAVVAAALRAIRAAAAPGTSSLS
MLBr_01831|M.leprae_Br4923          MGALTRLRSRRVVPQRSVGELDAMAAAGAVVAAALHAVRDAAGPGVSSLS
MMAR_1072|M.marinum_M               MRALARLRGRKVVPQRTAGELDAMAAAGAVVAAAHQAVRSAAVAGVSTLQ
MUL_0830|M.ulcerans_Agy99           MRALARLRGSRVVPQRTAGELDAMAAAGAVVAAAHQAVRSAAVAGVSTLQ
MAV_4432|M.avium_104                MNALARLRGRKVVPQRSDGELDAMAAAGAVVAAALQAVRAAAVAGVSTLS
MAB_3782c|M.abscessus_ATCC_199      ---MGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLE
                                       :      :.* **: .******.**::*. *  *::  * .* *:  

Mflv_5020|M.gilvum_PYR-GCK          LDRVAEAVIRDGGGVPSFLGYHGFPATICASVNDRVVHGIPTADETLAAG
Mvan_1349|M.vanbaalenii_PYR-1       LDEIAESVIRDGGGIPSFLGYHGFPASICASVNDRVVHGIPTAAEKLAAG
MSMEG_1485|M.smegmatis_MC2_155      LDRIAETVIRDGGGTPSFLGYHGFPASICASVNERVVHGIPSADEVLAAG
TH_3403|M.thermoresistible__bu      LDEIAESVIRDGGGIPSFLGYHGFPASICASVNERVVHGIPADDEILAAG
Rv0734|M.tuberculosis_H37Rv         LDEIAESVIRESGATPSFLGYHGYPASICASINDRVVHGIPSTAEVLAPG
Mb0755|M.bovis_AF2122/97            LDEIAESVIRESGATPSFLGYHGYPASICASINDRVVHGIPSTAEVLAPG
MLBr_01831|M.leprae_Br4923          LDEIAESVIREAGATPSFLRYHGYPATICTSVNDRVIHGIPSAVEILAPG
MMAR_1072|M.marinum_M               LDEIAESVIREAGATPSFLGYHGFPASICASVNDRVVHGIPSATEILGPG
MUL_0830|M.ulcerans_Agy99           LDEIAESVIREAGATPSFLGYHGFPASICASVNDRVVHGIPSATEILGPG
MAV_4432|M.avium_104                LDQIAESVIRDAGAVPSFLGYHGYPASICASVNDRVVHGIPSGAEVLAPG
MAB_3782c|M.abscessus_ATCC_199      LDQVAESVIREAGAVPSFLGYHGFPASICSSVNDQVVHGIPSATAVLADG
                                    **.:**:***:.*. **** ***:**:**:*:*::*:****:    *. *

Mflv_5020|M.gilvum_PYR-GCK          DLVSIDCGAILDGWHGDSALTFGVGDLIPADEALSAATRESMEAGIAAMV
Mvan_1349|M.vanbaalenii_PYR-1       DLVSIDCGAILDGWHGDSAVTFGVGEVIPVDESLSAATRESMEAGIAAMV
MSMEG_1485|M.smegmatis_MC2_155      DLVSIDCGAIVDGWHGDSAVTFGVGPLIPADEALSEATKAAMEAGIAAMV
TH_3403|M.thermoresistible__bu      DLVSIDCGAILDGWHGDSAITFGVGDLIPADEALSQATKAALDAGIDAMR
Rv0734|M.tuberculosis_H37Rv         DLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEATRESLQAGIAAMV
Mb0755|M.bovis_AF2122/97            DLVSIDCGAVLDGWHGDAAITFGVGALSDADEALSEATRESLQAGIAAMV
MLBr_01831|M.leprae_Br4923          DLVSIDCGAVLDGWHGDAAITFGVGTLTSVDEALSQATRESLEAGIAAMI
MMAR_1072|M.marinum_M               DLVSIDCGAVLDGWHGDAAITFGIGTLIPVDEALSEATRESLEAGIAAMV
MUL_0830|M.ulcerans_Agy99           DLVSIDCGAVLDGWHGDAAITFGIGTLIPVDEALSEATRESLEAGIAAMV
MAV_4432|M.avium_104                DLVSMDCGAVLDGWHGDAAITFGVGALDPADEALRQATRESLEAGIAAMV
MAB_3782c|M.abscessus_ATCC_199      DLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMI
                                    ****:****::******:* **.:* :   **:*  **: :::*** ** 

Mflv_5020|M.gilvum_PYR-GCK          PGNRLTDVSHAIEQGTRAAEARHGRKFGIVAGYGGHGIGREMHMDPFLAN
Mvan_1349|M.vanbaalenii_PYR-1       PGNRLSDVSHAIEQGTRAAAQRHGRKFGIVAGYGGHGIGREMHMDPFLPN
MSMEG_1485|M.smegmatis_MC2_155      PGNRLTDVSHAIEVETHAAEKRDDRKYGIVANYGGHGIGRQMYMDPFLPN
TH_3403|M.thermoresistible__bu      PGNRLTDVSHAIETATRAAERRDNRRYGIVANYGGHGIGRQMHMDPFLPN
Rv0734|M.tuberculosis_H37Rv         VGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGRQMHMDPFLPN
Mb0755|M.bovis_AF2122/97            VGNRLTDVAHAIETGTRAAELRYGRSFGIVAGYGGHGIGRQMHMDPFLPN
MLBr_01831|M.leprae_Br4923          VNNRLTDVAHAIEVSTRTSEIRYRLTFGIVQGYGGHGIGRHMHMDPFLPN
MMAR_1072|M.marinum_M               IGNRLTDVAHAIETETRAAEARYQRSFGIVDGYGGHGIGREMHMDPFLPN
MUL_0830|M.ulcerans_Agy99           IGNRLTDVAHAIETETRAAEARYQRSFGIVDGYGGHGIGREMHMDPFLPN
MAV_4432|M.avium_104                PGNRLTDVSHAIELGTRAAETRHGRAFGIVEGYGGHGIGRQMHMDPFLPN
MAB_3782c|M.abscessus_ATCC_199      PGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPN
                                     .***:**:****  *:::  :    :*** .******** *::****.*

Mflv_5020|M.gilvum_PYR-GCK          EGAPGRGPYLAPGSVLAIEPMLTLGTRKTLILDDGWTVVTADGTRAAHWE
Mvan_1349|M.vanbaalenii_PYR-1       EGSPGRGPYLAPGSVLAIEPMLTLGTAKTIVLDDGWTVVTADGSRAAHWE
MSMEG_1485|M.smegmatis_MC2_155      EGAPGRGPYLAPGSVLAIEPMLTLGTTKTVVLDDEWTVVTADGTRAAHWE
TH_3403|M.thermoresistible__bu      EGAPGRGPHLAVGSVLAIEPMLTLGTTETVVLADEWTVVTADGSRAAHWE
Rv0734|M.tuberculosis_H37Rv         EGAPGRGPLLAAGSVLAIEPMLTLGTTKTVVLDDKWTVTTADGSRAAHWE
Mb0755|M.bovis_AF2122/97            EGAPGRGPLLAAGSVLAIEPMLTLGTTKTVVLDDKWTVTTADGSRAAHWE
MLBr_01831|M.leprae_Br4923          EGAPGRGPLLVPGSVLAIEPMLTLGTGKTIVLDDEWTVTTADGSRAAHWE
MMAR_1072|M.marinum_M               EGAPGRGPTLVAGSVLAIEPMLTLGTRKTVVLDDQWTVITADGSRAAHWE
MUL_0830|M.ulcerans_Agy99           EGAPGRGPTLVAGSVLAIEPMLTLGTRKTVVLDDQWTVITADGSRAAHWE
MAV_4432|M.avium_104                EGSPGRGPLLAPGSVLAIEPMLTLGTGKTVVLDDQWTVITTDGSRAAHWE
MAB_3782c|M.abscessus_ATCC_199      EGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDGSRAAHWE
                                    **:**:** *. ************** :* :* * *** *:**:******

Mflv_5020|M.gilvum_PYR-GCK          HTVAVTDDGPRILTAR-
Mvan_1349|M.vanbaalenii_PYR-1       HTVAVTDDGPRILTV--
MSMEG_1485|M.smegmatis_MC2_155      HTVAVTEDGPRILTQ--
TH_3403|M.thermoresistible__bu      HTVAVTEDGPRILTL--
Rv0734|M.tuberculosis_H37Rv         HTVAVTDDGPRILTLG-
Mb0755|M.bovis_AF2122/97            HTVAVTDDGPRILTLG-
MLBr_01831|M.leprae_Br4923          HTVAVTEDGPRVLTLA-
MMAR_1072|M.marinum_M               HTVAVTENGPRILTLG-
MUL_0830|M.ulcerans_Agy99           HTVAVTENGPRILTLG-
MAV_4432|M.avium_104                HTVAVTDAGPRILTLG-
MAB_3782c|M.abscessus_ATCC_199      HTVAVTEAGPRILTMRP
                                    ******: ***:**