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MAGDRGADPGPANVTPGADDHAQHASPTVLCPQGHVNAWDYRFCERCGSPIGVVPWPSEESGTRQTAPAR SFVPLVVLAATLLVVAVVVTAVGYAVTRPARNDREEPSSARGAATTGVPFAQAEAASCPDDPVLEAESID LTSDGLAVSAAFMSACAGGDVESNSALEVTVADGRRDVAAGSFDFSADPLRIEPGVPARRTLVFPPGMYW RTPDMLSGAPALAATRKGRSDRSAARGGSARTTMVAAASAAPAYGSINAVAGAVLVELRDSDFPYVRVGI ANRWVPQVSSKRVGLVAAGKTWTSADILRDHLALRQRFGGARLVWSGHWTTFSGPDFWVTVVGPAQPTAA EANR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0621 | - | - | 100% (354) | POSSIBLE MEMBRANE PROTEIN |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0637 | - | 0.0 | 100.00% (354) | hypothetical protein Mb0637 |
| M. gilvum PYR-GCK | Mflv_5184 | - | 3e-86 | 49.39% (328) | hypothetical protein Mflv_5184 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_1190 | - | 7e-21 | 30.31% (320) | serine/threonine-protein kinase PknD |
| M. thermoresistible (build 8) | TH_1429 | - | 9e-17 | 59.68% (62) | serine/threonine-protein kinase PknD |
| M. ulcerans Agy99 | - | - | - | - | - |
| M. vanbaalenii PYR-1 | Mvan_1128 | - | 1e-89 | 50.76% (329) | hypothetical protein Mvan_1128 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0621|M.tuberculosis_H37Rv --------------------------------------------------
Mb0637|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5184|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1128|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1190|M.smegmatis_MC2_155 MALSQGAKIAGYTVERMLGSGGMGEVYLAQHPRLPRHDALKVLRANISAD
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv --------------------------------------------------
Mb0637|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5184|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1128|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1190|M.smegmatis_MC2_155 PAYVERFNKEADLAAKLWHPHIVGIHDRGKHRNRLWISMDFVDGTDASRL
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv --------------------------------------------------
Mb0637|M.bovis_AF2122/97 --------------------------------------------------
Mflv_5184|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1128|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_1190|M.smegmatis_MC2_155 LHDRYPDGMPVPEVLDIVKAVAAALDYAHGRGLLHRDVKPANILISDGDH
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv ---------------MAGDRGADPGPANVTPGADDHAQHASPTVLCPQGH
Mb0637|M.bovis_AF2122/97 ---------------MAGDRGADPGPANVTPGADDHAQHASPTVLCPQGH
Mflv_5184|M.gilvum_PYR-GCK ----------------------------MSDGFDG-----TPMVVCPHGH
Mvan_1128|M.vanbaalenii_PYR-1 ----------------------------MSSGYDG-----APMVACPHGH
MSMEG_1190|M.smegmatis_MC2_155 GERRILLGDFGVARDLGDSAGNGLTATNMTVGTAAYAAPEQLMGLELDGR
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv VNAWDYRFCERCGSPIG---------------------------------
Mb0637|M.bovis_AF2122/97 VNAWDYRFCERCGSPIG---------------------------------
Mflv_5184|M.gilvum_PYR-GCK LNAWHYKFCGQCGSPIG---------------------------------
Mvan_1128|M.vanbaalenii_PYR-1 LNAWNYKFCGQCGSPIG---------------------------------
MSMEG_1190|M.smegmatis_MC2_155 ADQYSLAATAYHLLTGGPLFENSNPAVVIGQHLNAPPPALGDSRPELAPL
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv ------------------VVPWPSEESGTRQTAPARSFVPLVVLAATLLV
Mb0637|M.bovis_AF2122/97 ------------------VVPWPSEESGTRQTAPARSFVPLVVLAATLLV
Mflv_5184|M.gilvum_PYR-GCK ------------------AVAFPDDDPVEVERRP-RRRGLLIGGAVAAVV
Mvan_1128|M.vanbaalenii_PYR-1 ------------------VVAFPDDDAVAEDERPLRRRGLAVGGAIAAVL
MSMEG_1190|M.smegmatis_MC2_155 DAALSRALAKNPDDRFATCTDFANALEHPQNHAATMTAPVPSPNDVPTML
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv VAVVVTAVGYAVTRPARNDREEPSSARGAATTGVPFAQAEAASCPDDPVL
Mb0637|M.bovis_AF2122/97 VAVVVTAVGYAVTRPARNDREEPSSARGAATTGVPFAQAEAASCPDDPVL
Mflv_5184|M.gilvum_PYR-GCK VIAAAVAVTVLMAGSSS-DDVAVPQS-GGFGAGPVDPAGMVPACTTPPLV
Mvan_1128|M.vanbaalenii_PYR-1 LAVIVAAVGFLMTRSSTGDDEAAPQA-GGFTPGTVNPAGMVPACTTAPLV
MSMEG_1190|M.smegmatis_MC2_155 APVAVPYPSGPAAPPPPNGSRYRRVALAAAAAAVVVAVVAAAALLIKPTE
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv EAESIDLTSDG------------LAVSAAFMSACAGGDVESNSALEVTVA
Mb0637|M.bovis_AF2122/97 EAESIDLTSDG------------LAVSAAFMSACAGGDVESNSALEVTVA
Mflv_5184|M.gilvum_PYR-GCK QAESVDMTGDG------------MTVDAAFMSRCAGGDTATAASVRITVA
Mvan_1128|M.vanbaalenii_PYR-1 QAESVDMTADG------------MTVDAAFMSQCPGGNTEASTSARITVA
MSMEG_1190|M.smegmatis_MC2_155 EAPSAEPFSIAGTLQLPPDVVKTNGLPSGFMCAGTSDYGDIGPETPITVE
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv DGRRDVAAG-------------SFDFSADPLRIEPGVPARRTLVFPPGMY
Mb0637|M.bovis_AF2122/97 DGRRDVAAG-------------SFDFSADPLRIEPGVPARRTLVFPPGMY
Mflv_5184|M.gilvum_PYR-GCK DGQRDIAAG-------------IFDFSAAPLTMKPGETARRTLVFPAGMY
Mvan_1128|M.vanbaalenii_PYR-1 DGQRDIAAG-------------VFDFSTAPLTMKPGETARRTLVFPAGTY
MSMEG_1190|M.smegmatis_MC2_155 NESGELLAKGAIESSSKGGNGCFLKFRVDDVPSG-ARFYRVHVAQRAEMS
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv WRTPDMLSGAPALAATRKGRSDRSAARGGSARTTMVAAASAAPAYGSINA
Mb0637|M.bovis_AF2122/97 WRTPDMLSGAPALAATRKGRSDRSAARGGSARTTMVAAASAAPAYGSINA
Mflv_5184|M.gilvum_PYR-GCK WRTTEMFSGAPQMVVHPGEQSDATTATASSGSDRLVAHAVAEPEHGSIDG
Mvan_1128|M.vanbaalenii_PYR-1 WRTTEMFTGAPQLVFHPGEQAEASTA-ASSGSDRLVAQTVAQPAHGSIDG
MSMEG_1190|M.smegmatis_MC2_155 YTEEEAKAGIQFLLGTVHDEPTPTTTAPPAKASPPPTATRTVTVTPKAED
TH_1429|M.thermoresistible__bu --------------------------------------------------
Rv0621|M.tuberculosis_H37Rv VAGAVLVELRDSDFPYVRVGIANRWVPQVSSKRVGLVAAGKTWTSADILR
Mb0637|M.bovis_AF2122/97 VAGAVLVELRDSDFPYVRVGIANRWVPQVSSKRVGLVAAGKTWTSADILR
Mflv_5184|M.gilvum_PYR-GCK VAEAVLRELRDADYGYVSTSIANRWVPQISAKKAGLVVDGATITSADVLR
Mvan_1128|M.vanbaalenii_PYR-1 VADAVLRELRDADYGYVSGSLANRWVPQISAKKSGLVVNGRTLTSADVLR
MSMEG_1190|M.smegmatis_MC2_155 TSLQRLRALANNDRPYVAAILADQWVPQISSKRAGLVADGVTWDNARILD
TH_1429|M.thermoresistible__bu --------------------XADRWVPQLSSKRPGIVDKGVTWDNALTLQ
*::****:*:*: *:* * * .* *
Rv0621|M.tuberculosis_H37Rv DHLALRQRFGGARLVWSGHWTTFSGPDFWVTVVGPAQPTAAEANR-----
Mb0637|M.bovis_AF2122/97 DHLALRQRFGGARLVWSGHWTTFSGPDFWVTVVGPAQPTAAEANRWCDSN
Mflv_5184|M.gilvum_PYR-GCK DHYGLRAKHSGVRLVSSAQWTTFDSDDFWVTVVGAPKLSPAEANGWCDAN
Mvan_1128|M.vanbaalenii_PYR-1 DHLDLREKYSGVRLVSSAQWTTFSSADFWVTVVGAPKLSPAEANAWCDAN
MSMEG_1190|M.smegmatis_MC2_155 QHMRMRATYPDVRLLWSGDWSTYDGRDFWVTIVGLTSDNPGEILAWCSSA
TH_1429|M.thermoresistible__bu EHLLLRQRY-DAVLVWSGDWSTFDAPNYWVTIVPVTFATPDGALAWCRAQ
:* :* . .. *: *..*:*:.. ::***:* . ..
Rv0621|M.tuberculosis_H37Rv --------------------------
Mb0637|M.bovis_AF2122/97 GFGADDCFAKFISTLVGAKGTTVYRK
Mflv_5184|M.gilvum_PYR-GCK RLGVDDCFAKFVSTLFGVEGTTAYRK
Mvan_1128|M.vanbaalenii_PYR-1 RLGVNDCFAKFVSSLFGVDGTTAYRK
MSMEG_1190|M.smegmatis_MC2_155 GFDRDNCAAKVVSTWRPIAGSTKYN-
TH_1429|M.thermoresistible__bu GLGRNDCYAKLVSTTHPVRGSTAHN-