For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0488 (-)

annotation: PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
coordinates: 577664 - 578269
length: 201

MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIADGALIAAGVGGFAALIHAHPNMTLVARFGGAAFLI
GYALLAARNAWRPSGLVPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFGAGAW
AASVVWFAVLGFSAGRLQPFFATPAAWRILDALVAVTMIGVAVVVLVTSPSVPTANVALII
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0488--100% (201)PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN
M. tuberculosis H37RvRv1986-6e-6463.44% (186) integral membrane protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0498-1e-111100.00% (201) integral membrane protein
M. gilvum PYR-GCKMflv_0373-2e-5959.14% (186) lysine exporter protein LysE/YggA
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4386-5e-5658.29% (187) putative transporter
M. marinum M-----
M. avium 104-----
M. smegmatis MC2 155MSMEG_0467-7e-5959.36% (187) membrane transport protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99-----
M. vanbaalenii PYR-1Mvan_0310-1e-5956.68% (187) lysine exporter protein LysE/YggA

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0373|M.gilvum_PYR-GCK          MSTTSLVVLSGFASSMALIAAIGAQNAFVLRQGIRGEHVLPVVAVCAVSD
Mvan_0310|M.vanbaalenii_PYR-1       MNPAYVVVLSGFATTMALIAAIGAQNAFVLRQGIRGEHVLPVVAVCTVSD
MSMEG_0467|M.smegmatis_MC2_155      MNSP---LVLGFLTSMALIAAIGAQNAFVLRQGIRREHVLPVIAVCTVSD
MAB_4386|M.abscessus_ATCC_1997      ----MTVLFLGFLTGMSLIAAIGAQNAFVLRQGIRSEHVLPVIAVCITGD
Rv0488|M.tuberculosis_H37Rv         --------------MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIAD
Mb0498|M.bovis_AF2122/97            --------------MMTLKVAIGPQNAFVLRQGIRREYVLVIVALCGIAD
                                                   *:* .***.*********** *:** ::*:*  .*

Mflv_0373|M.gilvum_PYR-GCK          LVLIAAGIAGVGALIAAHPDVVTVTRYGGAAFLIGYGLFAARRAVKPGVL
Mvan_0310|M.vanbaalenii_PYR-1       LVLISAGIAGFGALIAAHPDIVTATKFGGAAFLVGYGLLAARRAVKPGVL
MSMEG_0467|M.smegmatis_MC2_155      LLLITAGIAGVGAVITAHPDAVTVTKFGGAAFLIGYGVLAARRALRPSTL
MAB_4386|M.abscessus_ATCC_1997      FLLIAAGIGGLGGLITATPSLLTVAKVGGAAFLIGYGLMAARRALRPGTL
Rv0488|M.tuberculosis_H37Rv         GALIAAGVGGFAALIHAHPNMTLVARFGGAAFLIGYALLAARNAWRPSGL
Mb0498|M.bovis_AF2122/97            GALIAAGVGGFAALIHAHPNMTLVARFGGAAFLIGYALLAARNAWRPSGL
                                      **:**:.*...:* * *.   .:: ******:**.::***.* :*. *

Mflv_0373|M.gilvum_PYR-GCK          TPADAAPARLAAVLATCLALTFLNPHVYLDTVVLLGMLANEHQDSRWLFG
Mvan_0310|M.vanbaalenii_PYR-1       TPADAAPARLTAVLATCLAMTFLNPHVYLDTVILLGALANEHQDSKWLFG
MSMEG_0467|M.smegmatis_MC2_155      NPSERTPARLAEVLVTCLALTWLNPHVYLDTVVLLGTLANEQREQRWLFG
MAB_4386|M.abscessus_ATCC_1997      VPAESNPARLGAVLLTALAITFLNPHVYLDTVVLLGSLANAHRDARWLFG
Rv0488|M.tuberculosis_H37Rv         VPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFG
Mb0498|M.bovis_AF2122/97            VPSESGPAALIGVVQMCLVVTFLNPHVYLDTVVLIGALANEESDLRWFFG
                                     *::  ** *  *:  .*.:*:**********:*:* *** . : :*:**

Mflv_0373|M.gilvum_PYR-GCK          VGAVTASAVWFAGLGFGATRVRHWFASPRTWRLLDAAIAAVMIALGVSLL
Mvan_0310|M.vanbaalenii_PYR-1       VGAVAASALWFTGLGFGAKRLRHLFASPKTWRLLDGVIAATMLALGISLV
MSMEG_0467|M.smegmatis_MC2_155      AGAVLASAIWFLGLGLGAKRLAGLFATPMTWRILDGVIAVTMIALGLGMM
MAB_4386|M.abscessus_ATCC_1997      AGALTASVTWFVGLGYGARYLAGVFERPGTWRMLDAGIAVVMLALGVSLL
Rv0488|M.tuberculosis_H37Rv         AGAWAASVVWFAVLGFSAGRLQPFFATPAAWRILDALVAVTMIGVAVVVL
Mb0498|M.bovis_AF2122/97            AGAWAASVVWFAVLGFSAGRLQPFFATPAAWRILDALVAVTMIGVAVVVL
                                    .**  **. **  ** .*  :   *  * :**:**. :*..*:.:.: ::

Mflv_0373|M.gilvum_PYR-GCK          MR-------------
Mvan_0310|M.vanbaalenii_PYR-1       VS-------------
MSMEG_0467|M.smegmatis_MC2_155      LT-------------
MAB_4386|M.abscessus_ATCC_1997      VS-------------
Rv0488|M.tuberculosis_H37Rv         VTSPSVPTANVALII
Mb0498|M.bovis_AF2122/97            VTSPSVPTANVALII
                                    :