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M. tuberculosis H37Rv Rv0478 (deoC)

annotation: deoxyribose-phosphate aldolase
coordinates: 567222 - 567896
length: 224

VLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMVPVAVQAGGVRVAAVTGFPSG
KHVSSVKAHEAAAALASGASEIDMVIDIGAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNA
HTLVDACRAAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAADAVAMLNAGATR
LGLSGTRAVLDGLS
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0478deoC-100% (224)deoxyribose-phosphate aldolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0488deoC1e-120100.00% (224) deoxyribose-phosphate aldolase
M. gilvum PYR-GCKMflv_0097-2e-7871.30% (223) deoxyribose-phosphate aldolase
M. leprae Br4923MLBr_02451deoC5e-9278.32% (226) deoxyribose-phosphate aldolase
M. abscessus ATCC 19977MAB_4078c-1e-7770.97% (217) deoxyribose-phosphate aldolase (DeoC)
M. marinum MMMAR_0803deoC2e-9479.64% (221) deoxyribose-phosphate aldolase DeoC
M. avium 104MAV_4672deoC4e-9582.27% (220) deoxyribose-phosphate aldolase
M. smegmatis MC2 155MSMEG_0922deoC1e-7971.23% (219) deoxyribose-phosphate aldolase
M. thermoresistible (build 8)TH_0872deoC2e-4570.99% (131) PROBABLE DEOXYRIBOSE-PHOSPHATE ALDOLASE DEOC
M. ulcerans Agy99MUL_4546deoC1e-9479.64% (221) deoxyribose-phosphate aldolase
M. vanbaalenii PYR-1Mvan_0811-2e-8071.17% (222) deoxyribose-phosphate aldolase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0097|M.gilvum_PYR-GCK          -MGSYTRAQVAALVDHTLLKPEATEADIEAVVAEALALEVKAICVSPTFV
Mvan_0811|M.vanbaalenii_PYR-1       -MGSYSRARVAALVDHTLLKPEATEADIEALVTEAAELGVYAICVSPTFV
Rv0478|M.tuberculosis_H37Rv         MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMV
Mb0488|M.bovis_AF2122/97            MLGQPTRAQLAALVDHTLLKPETTRADVAALVAEAAELGVYAVCVSPSMV
MLBr_02451|M.leprae_Br4923          MQGQPTRKQLAALVDHTLLKSEATHADVAALVAEAVELGVYAVCVSPSMV
MAV_4672|M.avium_104                MT--PTRAQLAAFVDHTLLKPEATAADVAALVTEAAELGVYAVCVSPPMV
MMAR_0803|M.marinum_M               MPGQPTRDQVAALVDHTLLKPEATAADVVALVAEAADLGVYAVCVSPSMV
MUL_4546|M.ulcerans_Agy99           MPGQPTRDQVAALVDHTLLKPEATAADVVALVAEAADLGVYAVCVSPSMV
TH_0872|M.thermoresistible__bu      --------------------------------------------------
MSMEG_0922|M.smegmatis_MC2_155      -MTDHTRAQVAALVDHTLLKPEATPSDVTALVDEAADLGVFAVCVSPPLV
MAB_4078c|M.abscessus_ATCC_199      ---------MAALIDHTLLKPEATPEDVRALVAEAVDLGVLAVCVSPSML
                                                                                      

Mflv_0097|M.gilvum_PYR-GCK          AAVASLAP-AATVASVVGFPSGKHLSSVKAAEAHAAAAAGAAEIDMVIDV
Mvan_0811|M.vanbaalenii_PYR-1       AAVSLLAP-DATVASVVGFPSGKHVSAIKAEEARLAVEAGAREVDMVIDV
Rv0478|M.tuberculosis_H37Rv         PVAVQAG--GVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDI
Mb0488|M.bovis_AF2122/97            PVAVQAG--GVRVAAVTGFPSGKHVSSVKAHEAAAALASGASEIDMVIDI
MLBr_02451|M.leprae_Br4923          PAAVEAGAGGLRVATVVGFPSGEHVSIVKAQEAVQAVASGATEIDMVIAV
MAV_4672|M.avium_104                PAAVQAG-AGVRVASVAGFPSGKHVSAVKAHEAALAVASGAAEIDMVIDV
MMAR_0803|M.marinum_M               PAAVSAG--GVRVATVAGFPSGKHASAIKAHEAALAVACGAVEVDMVIDV
MUL_4546|M.ulcerans_Agy99           PAAVSAG--GVRVATVAGFPSGKHASAIKAHEAALAVACGAVEVDMVIDV
TH_0872|M.thermoresistible__bu      ---------------------------------------------MVIDV
MSMEG_0922|M.smegmatis_MC2_155      SVAAGVAPSGLAIAAVAGFPSGKHVPGIKATEAELAVAAGATEIDMVIDV
MAB_4078c|M.abscessus_ATCC_199      PVLLPEGVERLLVAGVVGFPSGKHLSSVKAHEAALAVAAGAHEIDMVIDV
                                                                                 *** :

Mflv_0097|M.gilvum_PYR-GCK          GAALAGQLDAVRADIAAVRAAAPETVLKVIVESAALLEFGGQPILLDVCR
Mvan_0811|M.vanbaalenii_PYR-1       GCALAGELGAVRSDIAAVRAAAPEAVLKVIVESAAILQISGEPLLVDICR
Rv0478|M.tuberculosis_H37Rv         GAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACR
Mb0488|M.bovis_AF2122/97            GAALCGDIDAVRSDIEAVRAAAAGAVLKVIVESAVLLGQSNAHTLVDACR
MLBr_02451|M.leprae_Br4923          GAALAGDLDAVRSDIEMVRSAIAGVVLKVIVESAVLLGQANERTLAEVCH
MAV_4672|M.avium_104                GAALAGDLDGVRADIAAVRGAVGGAVLKVIVESSALLALADEHTLVRVCR
MMAR_0803|M.marinum_M               GAALAGHLDAVRSDIEAVRCATSGAVLKVIVESAALLGLADESTLIGVCR
MUL_4546|M.ulcerans_Agy99           GAALAGHLDAVRSDIEAVRCATSGAVLKVIVESAALLGLADESTLIGVCR
TH_0872|M.thermoresistible__bu      GAAVAGELGAVYDDIAEVRRAVSGITLKVIVESAVLLEHTDPERLTAVCR
MSMEG_0922|M.smegmatis_MC2_155      GAALAGDLDAVSADITAVRKAVRAATLKVIVESAALLEFSGEPLLADVCR
MAB_4078c|M.abscessus_ATCC_199      GAAVGGDFGAVQGDIEAVRRAVPAATLKVIIESAALLERSGPEAVRAACR
                                    *.*: *.:..*  **  ** *    .****:**:.:*   .   :   *:

Mflv_0097|M.gilvum_PYR-GCK          IAEDAGAEFVKTSTGFHPSGGASPRAVELMAGAVGGRLGVKASGGIRTAA
Mvan_0811|M.vanbaalenii_PYR-1       VAEDAGADFVKTSTGFHPSGGASVRAVELMAGAVGGRLGVKASGGIRSAA
Rv0478|M.tuberculosis_H37Rv         AAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAA
Mb0488|M.bovis_AF2122/97            AAEDAGADFVKTSTGCHPAGGATVRAVELMAETVGPRLGVKASGGIRTAA
MLBr_02451|M.leprae_Br4923          VAEAAGADFVKTSTGFHPAGGASVRAVTLMTEAVGGRLGVKASGGIRTAV
MAV_4672|M.avium_104                AAEDAGADFVKTSTGFHPSGGASVRAVALMAEAVGGRLGVKASGGIRTAA
MMAR_0803|M.marinum_M               VAEDAGADFVKTSTGFHPAGGASTRAVEVMASAVGGRLGVKASGGIRTAT
MUL_4546|M.ulcerans_Agy99           VAEDAGADFVKTSTGFHPAGGASTRAVEVMASAVGGRLGVKASGGIRTAT
TH_0872|M.thermoresistible__bu      AAEDAGADFVKTSTGFHPSGGASVQAVSVMAAAVGGRLGVKASGGIRTAA
MSMEG_0922|M.smegmatis_MC2_155      VARDAGADFVKTSTGFHPSGGASVQAVEIMARTVGERLGVKASGGIRTAE
MAB_4078c|M.abscessus_ATCC_199      ASEAAGADFVKTSTGFHPAGGATVEAVRIMAETVGDRLQVKASGGIRTAR
                                     :. ***:******* **:***: .** :*: :** ** ********:* 

Mflv_0097|M.gilvum_PYR-GCK          AATEMLDAGATRLGLSGTRAVLDGLRA-
Mvan_0811|M.vanbaalenii_PYR-1       DAAAMLDAGATRLGLSGTRAVLAGFPD-
Rv0478|M.tuberculosis_H37Rv         DAVAMLNAGATRLGLSGTRAVLDGLS--
Mb0488|M.bovis_AF2122/97            DAVAMLNAGATRLGLSGTRAVLDGLS--
MLBr_02451|M.leprae_Br4923          DAIALLDAGATRLGLSSTREVLDGLS--
MAV_4672|M.avium_104                DALAMLDAGATRLGLSGTRAVLDGLG--
MMAR_0803|M.marinum_M               DAVAMLSAGATRLGLSGTRAVLEGLGQN
MUL_4546|M.ulcerans_Agy99           DAVAMLSAGATRLGLSGTRAVLEGLGQN
TH_0872|M.thermoresistible__bu      DAVAMLDAGATRLGLSASRAVLDGLT--
MSMEG_0922|M.smegmatis_MC2_155      QAAAMLDAGATRLGLSGSRAVLDGFGSA
MAB_4078c|M.abscessus_ATCC_199      DAAAMLEAGATRLGLSGSRIVLDGFAD-
                                     *  :*.*********.:* ** *: