For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. tuberculosis H37Rv Rv0461 (-)

annotation: PROBABLE TRANSMEMBRANE PROTEIN
coordinates: 552026 - 552550
length: 174

VPDFDTGAHSQRFLSLAGQQDRAGKSWPGSTPKPQEDPVGVAPSASVEVLGSEPAATLAHSVTVPGRYTY
LKWWKFVLVVLGVWIGAGEVGLSLFYWWYHTLDKTAAVFVVLVYVVACTVGGLILALVPGRPLITALSLG
VMSGPFASVAAAAPLYGYYYCERMSHCLVGVIPY
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0461--100% (174)PROBABLE TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0470-1e-101100.00% (174) hypothetical protein Mb0470
M. gilvum PYR-GCKMflv_0120-5e-2447.52% (101) hypothetical protein Mflv_0120
M. leprae Br4923-----
M. abscessus ATCC 19977MAB_4128c-7e-1937.27% (161) hypothetical protein MAB_4128c
M. marinum MMMAR_0783-4e-5260.11% (178) transmembrane protein
M. avium 104MAV_4688-2e-4752.02% (173) hypothetical protein MAV_4688
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_2920-4e-3040.61% (165) PUTATIVE putative conserved hypothetical protein
M. ulcerans Agy99MUL_1419-1e-5159.55% (178) transmembrane protein
M. vanbaalenii PYR-1Mvan_0793-4e-2544.09% (127) hypothetical protein Mvan_0793

CLUSTAL 2.0.9 multiple sequence alignment


Rv0461|M.tuberculosis_H37Rv         -----------------------------------------------MPD
Mb0470|M.bovis_AF2122/97            -----------------------------------------------MPD
MMAR_0783|M.marinum_M               ---------------------------------------------MAKDD
MUL_1419|M.ulcerans_Agy99           ---------------------------------------------MAKDD
MAV_4688|M.avium_104                ---------------------------------------------MADDK
Mflv_0120|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0793|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_2920|M.thermoresistible__bu      ---------------------------------------------VPDRR
MAB_4128c|M.abscessus_ATCC_199      MSDKNAENTVEKTDAEADGAAAELVDDADQPSVVEGDLADPLAVPIDDGK
                                                                                      

Rv0461|M.tuberculosis_H37Rv         FDTGAHSQRFLS----------LAGQQ---DRAGKSWPG------STPKP
Mb0470|M.bovis_AF2122/97            FDTGAHSQRFLS----------LAGQQ---DRAGKSWPG------STPKP
MMAR_0783|M.marinum_M               LDSNPGTEPFVPEFDTGERSVPFVPDF---DTDSKPFAGLAAVVTESKKS
MUL_1419|M.ulcerans_Agy99           LDSNPGTEP-------------FVPDF---DMDSKPFAGLAAVVTESKKS
MAV_4688|M.avium_104                DASSPGTEAFVP---------DFSDDDDAADTGTQSWAP--DFDDDAEDD
Mflv_0120|M.gilvum_PYR-GCK          ----------------------MS-EQTILEDPS----------------
Mvan_0793|M.vanbaalenii_PYR-1       ----------------------MSEDQIALDDPA----------------
TH_2920|M.thermoresistible__bu      SETLPGEPTGQYTP----VFDTGSFTAVQPDDPARVWEA-DPVKPLAAEF
MAB_4128c|M.abscessus_ATCC_199      ARDGLDTATFTAFSAFKDDEDDLVPTG-RIDTDALPLTEAFDVGSDRTGA
                                                                  :                   

Rv0461|M.tuberculosis_H37Rv         QEDPVGVAP-SASVEVLG---------SEPAATLAHSVTVPG--RYTYLK
Mb0470|M.bovis_AF2122/97            QEDPVGVAP-SASVEVLG---------SEPAATLAHSVTVPG--RYTYLK
MMAR_0783|M.marinum_M               SVELVDLSEVSAPLTTLDGDSLDGDSPAEGTATPAPSVTVPS--RYVYLK
MUL_1419|M.ulcerans_Agy99           SVELVDLSEVSAPLTTLDGDSLDGDSPAEGTATPAPSVTVPS--RYVYLK
MAV_4688|M.avium_104                DTEAAEPAAERGPEPEPEPE-------PAGFAGPVPPVAVPG--RYFYVK
Mflv_0120|M.gilvum_PYR-GCK          ------------PSNELP-------------PPHAQPIVVPS--AEQSVS
Mvan_0793|M.vanbaalenii_PYR-1       ------------YADELP-------------RPPAQPVVVPA--AAQSVG
TH_2920|M.thermoresistible__bu      EPATDSPQTGDVPIGELPS---------EPIPAPARPMVVPG--SYQFLK
MAB_4128c|M.abscessus_ATCC_199      IPAAVGRSRAEAMTPDPYTG-----AVPVLGDEPAKPVRVPAEREPALLK
                                                                      . .: **.      : 

Rv0461|M.tuberculosis_H37Rv         WWKFVLVVLGVWIGAGEVGLSLFYWWYHTL---DKTAAVFVVLVYVVACT
Mb0470|M.bovis_AF2122/97            WWKFVLVVLGVWIGAGEVGLSLFYWWYHTL---DKTAAVFVVLVYVVACT
MMAR_0783|M.marinum_M               WWKFVLVVLGVWFGAAQVGLSLFYWWFHTI---DKTLPVFVVLVYLVLCA
MUL_1419|M.ulcerans_Agy99           WWKFVLVVLGVWFGAAQVGLSLFYWWFHTI---DKTLPVFVVLVYLVLCA
MAV_4688|M.avium_104                WWKLVLVLLAVWAASAVVGLGLFSWWYHSI---DKTPALFAVLVFVVVCV
Mflv_0120|M.gilvum_PYR-GCK          RWRFVLVTAGMWIAAAAAGAGLYYWWFHGA---DKSLPVFAVLVFVVACT
Mvan_0793|M.vanbaalenii_PYR-1       RWRFVLVVAGMWIVAAAAGAGLYYWWYHSP---DKAVPVFAVLVFVVACI
TH_2920|M.thermoresistible__bu      RWVFALVVAGVWTVAAAGGLGLYHWWYVSL---DKTPTVATLLIYLMVST
MAB_4128c|M.abscessus_ATCC_199      RWVLLLILVGTWIPAAAVGLLLYQNWFATLLPHDRIVAVEYVLAWVFACV
                                     * : *:  . *  :.  *  *:  *:      *:  .:  :* ::. . 

Rv0461|M.tuberculosis_H37Rv         VGGLILALVPGRPLITALSLGVMSGPFASVAAAAPLYGYYYCERMSHCLV
Mb0470|M.bovis_AF2122/97            VGGLILALVPGRPLITALSLGVMSGPFASVAAAAPLYGYYYCERMSHCLV
MMAR_0783|M.marinum_M               VASLLLSMVQGRPLITALSLALMSAPFASVAAAAPLYGSYFCEHASRCLA
MUL_1419|M.ulcerans_Agy99           VASLLLSMVQGRPLITALSLALMSAPFASVAAAAPLYGSYFCEHASRCLA
MAV_4688|M.avium_104                VGGVMLAMVEARPLISALAVAVLSGPFAALAAAAPLYGYYYCARVGHCLV
Mflv_0120|M.gilvum_PYR-GCK          VGSLLTAMVQERPGLAAMSLALMSAPLAAALGAGGLYASYVFGWIST---
Mvan_0793|M.vanbaalenii_PYR-1       VGSLLTAMVQDRPGVAATAIAMMSAPLAAAVGAAVLYGAYVFEWIAR---
TH_2920|M.thermoresistible__bu      VAGMLLAMVQTKPVVSGLAIALMSAPFASTMAAAALHGAYYFNWLNP---
MAB_4128c|M.abscessus_ATCC_199      LIALLLAMFEPRPLIVALAFAVLTAPAISVAAAGVKYGYVACTAPSVPGV
                                    : .:: ::.  :* : . :..:::.*  :  .*.  :.            

Rv0461|M.tuberculosis_H37Rv         GVIPY--------------
Mb0470|M.bovis_AF2122/97            GVIPY--------------
MMAR_0783|M.marinum_M               GVIPY--------------
MUL_1419|M.ulcerans_Agy99           GVIPY--------------
MAV_4688|M.avium_104                GVVPY--------------
Mflv_0120|M.gilvum_PYR-GCK          -------------------
Mvan_0793|M.vanbaalenii_PYR-1       -------------------
TH_2920|M.thermoresistible__bu      -------------------
MAB_4128c|M.abscessus_ATCC_199      KSLCPEPLRSWGIQYRDRA