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M. tuberculosis H37Rv Rv0426c (-)

annotation: POSSIBLE TRANSMEMBRANE PROTEIN
coordinates: 515373 - 515816
length: 147

SVVGGTVRTVGRTVSGAATATTAAAGAVGGAAVSGIVGGVTGAAKGIQKGLSSGSKSTAAAALAIGAIGV
AGLVDWPILLAVGGGALLLRKLNRTPEVAAPPVKAKLAPVPDKPAAAKEAPAKASKTTARKTSGRRAGTA
ELRSTN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0426c--100% (147)POSSIBLE TRANSMEMBRANE PROTEIN
M. tuberculosis H37RvRv3511PE_PGRS558e-0538.37% (86) PE-PGRS family protein
M. tuberculosis H37RvRv3508PE_PGRS548e-0536.99% (73) PE-PGRS family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0434c-2e-76100.00% (147) transmembrane protein
M. gilvum PYR-GCKMflv_5091-3e-0536.99% (73) triple helix repeat-containing collagen
M. leprae Br4923MLBr_01932-6e-4160.43% (139) hypothetical protein MLBr_01932
M. abscessus ATCC 19977-----
M. marinum MMMAR_0741-1e-5572.97% (148) transmembrane protein
M. avium 104MAV_4728-4e-4464.75% (139) hypothetical protein MAV_4728
M. smegmatis MC2 155-----
M. thermoresistible (build 8)TH_3941-5e-2847.71% (153) PUTATIVE -
M. ulcerans Agy99MUL_1373-8e-5672.97% (148) transmembrane protein
M. vanbaalenii PYR-1Mvan_5798-4e-3254.79% (146) putative transmembrane protein

CLUSTAL 2.0.9 multiple sequence alignment


Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          MVTFGGGATPTPTSLGAAAVDLSGTSCGLICNGQDGTGQNGGILFGNGGS
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        ----------------MSVVGGTVRTVGRTVS------------------
Mb0434c|M.bovis_AF2122/97           ----------------MSVVGGTVRTVGRTVS------------------
MMAR_0741|M.marinum_M               ----------------MGVVGGAVRNVGQTVN------------------
MUL_1373|M.ulcerans_Agy99           ----------------MGVVGGAVRNVGQTVN------------------
MLBr_01932|M.leprae_Br4923          -------------------MG---RGLGKAVS------------------
MAV_4728|M.avium_104                --------------------------MSQAVN------------------
TH_3941|M.thermoresistible__bu      --------------VKGGNAMDVVGSALRTVR------------------
Mvan_5798|M.vanbaalenii_PYR-1       -----MMSTQQPVSGIGGVPMNPISTAFRGLT------------------
Mflv_5091|M.gilvum_PYR-GCK          GWNSDVVGMDGGNGGNGGLFGGNGGNGGNGLGGGNGGNGGNAGAFALFGN
                                                                . :                   

Rv0426c|M.tuberculosis_H37Rv        -----GAATATTAAAGAVGGAAVS----------GIVGGVTGAAKGIQKG
Mb0434c|M.bovis_AF2122/97           -----GAATATTAAAGAVGGAAVS----------GIVGGVTGAAKGIQKG
MMAR_0741|M.marinum_M               -----RAATATTAAAGAVGGAAVN----------GVVGGVKGAAEGIQRG
MUL_1373|M.ulcerans_Agy99           -----RAATATTAAAGAVGGAAVN----------GVVGGVKGAAEGIQRG
MLBr_01932|M.leprae_Br4923          -----RAAIATTAAAGAVGGAAVN----------SIVGGVTGAAEGVKRG
MAV_4728|M.avium_104                -----RAASATTAAAGAVGGAAVN----------GVIGGVTGAAEGVKRG
TH_3941|M.thermoresistible__bu      -----KAAEVTTSAAGAVGGAAVN----------GVIGAAQGAVSGAREG
Mvan_5798|M.vanbaalenii_PYR-1       -----KVADATTAAAGAVGGAAVS----------GVVGGVQGAAGGIRSG
Mflv_5091|M.gilvum_PYR-GCK          GGNGGNGGVGVVGATGAVGAPGVAGATGATGVTSGVVGGNGEDAVGYGAT
                                           .  ...*:****...*           .::*.    . *    

Rv0426c|M.tuberculosis_H37Rv        LSSGSKSTAAAALAIGAIGVAGLVDWPILLAVGGGALLLRKLNR-----T
Mb0434c|M.bovis_AF2122/97           LSSGSKSTAAAALAIGAIGVAGLVDWPILLAVGGGALLLRKLNR-----T
MMAR_0741|M.marinum_M               LSTGSKSTPAAALAMGALGVAGIVEWPILLAVGGSALLLRRMSQ-----R
MUL_1373|M.ulcerans_Agy99           LSTGSKSTPAAALAMGALGVAGIVEWPILLAVGGSALLLRRMSQ-----R
MLBr_01932|M.leprae_Br4923          IRTGRHSTSTAALVLGALGVAGLVEWPILLAVGGGALLLSKMRP-----I
MAV_4728|M.avium_104                MNSGSHSTPAAALAFGALGVAGLVEWPVLLAVGGGALLLQRLNR-----K
TH_3941|M.thermoresistible__bu      VEKGSDSTPAALLTLGAIGATGLIEWPIVLAVGGSALLIRQLSRSSGTDR
Mvan_5798|M.vanbaalenii_PYR-1       LSSGSRSTAAAALTLGAIGAAGLVEWPVLVTVGGAALVMHQLGQ------
Mflv_5091|M.gilvum_PYR-GCK          GAAGAAGAAGAAGAAGAVGSAGAAGEAGETGTWGNAGLPGKAGDAG---G
                                       *  .:. *  . **:* :*    .    . * * :  :         

Rv0426c|M.tuberculosis_H37Rv        PEVAAP-PVKAKLAPVPDKPAAAKEAP--AKA-SKTTARKTSGRRAGTAE
Mb0434c|M.bovis_AF2122/97           PEVAAP-PVKAKLAPVPDKPAAAKEAP--AKA-SKTTARKTSGRRAGTAE
MMAR_0741|M.marinum_M               PEASAP-AAKAKLAPVPDQEEPAKAAP--QKAPAKTAAKKSTGRRAGAAE
MUL_1373|M.ulcerans_Agy99           PEASAP-AAKAKLAPVPDQEEPAKAAP--QKAPAKTAAKKSTGRRAGAAE
MLBr_01932|M.leprae_Br4923          PDPAAP-EAKAKLKPVP-----TNSTQ--RKSTSKPAAKKTTRRRTATTE
MAV_4728|M.avium_104                ERQPEPRAVKANLKSVPAESAPARKAP--AKTAAKSTAKKAPGRRAGAGD
TH_3941|M.thermoresistible__bu      EAASDAAAGEPNLKVVDDTTGSGATSRGATRKATKPGSRKTSRSRATSKS
Mvan_5798|M.vanbaalenii_PYR-1       -RARQP--AAPRQSTAP----PAKKTA---ARPAKTARKTTASRRATAK-
Mflv_5091|M.gilvum_PYR-GCK          AGAVGAAGAAGTVGTAGATGGTGTGANGGAGGVGGVGGTGAAGAAGGAGG
                                         .         .         :              :.     :  

Rv0426c|M.tuberculosis_H37Rv        LRSTN---------------------------------------------
Mb0434c|M.bovis_AF2122/97           LRSTN---------------------------------------------
MMAR_0741|M.marinum_M               LRSTN---------------------------------------------
MUL_1373|M.ulcerans_Agy99           LRSTN---------------------------------------------
MLBr_01932|M.leprae_Br4923          LQGTN---------------------------------------------
MAV_4728|M.avium_104                LRSTN---------------------------------------------
TH_3941|M.thermoresistible__bu      AR------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          LGETGTTGGAGGVGGQGTAGGTGGVGGIGGAGSTGAVGGVGGKGIQGGQG
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          LQGGKGGDGGAGGKGGDADSMGSAGATGGKGGNGGNGGRGGLFGKGGNAG
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          NGADGGTGGAGGAGGTGGTGGAGGTGGTGGTGGIGGAGSTGGTGGTGGTG
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GTGGTGGTGGTGGTGGTGGTGGKGGTGGTGGAGGTGGDGGTGGTGGTGGT
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGTGGTGGTGGAGDGTGGTGGTGGTGGQGGQGGQGGTGGTGGQGGLGGGG
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GTGGQGGTGGTGGQGGTGGTGGTGGTGGTGGAGGDGGLGGLGGFGGSGGT
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGQGGLGGPGGSTGGAGGAGGQAGTAGKGGLFGGSGSAGKAGATGAAGAS
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          GGKGAQGATGAQGATGAQGATGATGAAGKAGATGAAGAAGAAGSAGTTGA
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          QGSAGTNGANGANGSQGAAGKAGATGTTGATGAAGEDGDAGSGGSGINGG
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        --------------------------------------------------
Mb0434c|M.bovis_AF2122/97           --------------------------------------------------
MMAR_0741|M.marinum_M               --------------------------------------------------
MUL_1373|M.ulcerans_Agy99           --------------------------------------------------
MLBr_01932|M.leprae_Br4923          --------------------------------------------------
MAV_4728|M.avium_104                --------------------------------------------------
TH_3941|M.thermoresistible__bu      --------------------------------------------------
Mvan_5798|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_5091|M.gilvum_PYR-GCK          AGGAGGAGGEGGEGGDGGKGGAGAEGGAGGGGGAGGSGAGGAGGAGGSGG
                                                                                      

Rv0426c|M.tuberculosis_H37Rv        -------------------
Mb0434c|M.bovis_AF2122/97           -------------------
MMAR_0741|M.marinum_M               -------------------
MUL_1373|M.ulcerans_Agy99           -------------------
MLBr_01932|M.leprae_Br4923          -------------------
MAV_4728|M.avium_104                -------------------
TH_3941|M.thermoresistible__bu      -------------------
Mvan_5798|M.vanbaalenii_PYR-1       -------------------
Mflv_5091|M.gilvum_PYR-GCK          SGGSGGSGGSGGAAGDSDD