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TTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQPASGRTDNLGTRIWTQISEVLGQRRLLKWSIPG LAHFFTMWGFFILLTVYIEAYGLLFEERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREI GRSSRFYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVNNGTLPYGNGAFLSQLFGAILRPLGQPANEIIET TALLLHIGVMLAFLILVLHSKHLHIFLAPINVTFKRLPDGLGPLLPLEADGKPIDFENPSEDAVFGRGKI EDFTWKGMLDFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQKDASAGGEAGHQEH HHVPESGFGRVPGHGPEQATRPLVGTEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVM MESEFPSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYEYLFWVGCAGAYDDKA KKTTKAVAELLAVARVKYLVLGAGETCNGDSARRSGNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTC PHCFNTIGKEYRQLGANYTVLHHTQLLNRLVRDKRLVPVTPVSQDITYHDPCYLGRHNKAYEAPRELIGA AGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERVDEALATDATAIATACPFCRVMVTDGVNDRQ EEAGRSGVEVLDVAQVLLGSLDHDKAQLPAKGTAAKQAQERAPKAAPKAAAPVTPVEAPAEAPQAPAPAA PAAPVKGLGMAAGAKRPGAKKAAPTPAAPAAPAAPVKGLGIAAGAKRPGAKKTPPPAPGLAEPAAQPQPE AKPQPEPAAPPKPQTDGDPAAPAAPVKGLGIARGARPPGKR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0338c | - | - | 100% (882) | PROBABLE IRON-SULFUR-BINDING REDUCTASE |
| M. tuberculosis H37Rv | Rv3879c | - | 8e-10 | 27.27% (165) | hypothetical protein Rv3879c |
| M. tuberculosis H37Rv | Rv3876 | - | 4e-09 | 30.18% (169) | hypothetical protein Rv3876 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0345c | - | 0.0 | 99.77% (882) | putative iron-sulfur-binding reductase |
| M. gilvum PYR-GCK | Mflv_0278 | - | 0.0 | 69.03% (930) | hypothetical protein Mflv_0278 |
| M. leprae Br4923 | MLBr_02501 | - | 0.0 | 78.16% (893) | putative iron-sulphur-binding reductase |
| M. abscessus ATCC 19977 | MAB_4293 | - | 0.0 | 53.74% (910) | putative Fe-S oxidoreductase |
| M. marinum M | MMAR_0611 | - | 0.0 | 78.30% (986) | iron-sulphur-binding reductase |
| M. avium 104 | MAV_4817 | - | 0.0 | 81.05% (913) | ferredoxin, 4Fe-4S |
| M. smegmatis MC2 155 | MSMEG_0690 | - | 0.0 | 68.45% (935) | iron-sulfur cluster-binding protein |
| M. thermoresistible (build 8) | TH_2670 | - | 1e-24 | 44.10% (161) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0574 | - | 0.0 | 78.33% (983) | iron-sulphur-binding reductase |
| M. vanbaalenii PYR-1 | Mvan_0619 | - | 0.0 | 68.51% (959) | hypothetical protein Mvan_0619 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0278|M.gilvum_PYR-GCK -METQMLIRIIAGVLMLAVVGVFAAKRVLWLTKLIRSGQPLSEGNNRKDH
Mvan_0619|M.vanbaalenii_PYR-1 -MDTQMLIRIVVGVLMIAVVGVFAVKRVLWLTTLIRSGQPMSEGNNRKDH
Rv0338c|M.tuberculosis_H37Rv -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN
Mb0345c|M.bovis_AF2122/97 -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN
MMAR_0611|M.marinum_M -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD
MUL_0574|M.ulcerans_Agy99 -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD
MAV_4817|M.avium_104 -MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGK---PAPGHTDD
MLBr_02501|M.leprae_Br4923 -MTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQ---PANGRTDE
MSMEG_0690|M.smegmatis_MC2_155 MAHTLEVSRLIIGLLMTAIVLVFAAKRVLWLTKLIRSGQKTLDENGRKND
MAB_4293|M.abscessus_ATCC_1997 -MSTATITLGIIGVIFSLVAWGSFFGGVVKMVRVILSGQ---PDRTRFRP
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK LQKRITTQFEEVFGQTRLLRWSIPGIAHFFTMWGFFVLATVYLEAFGLLV
Mvan_0619|M.vanbaalenii_PYR-1 LKQRITTQFEEVFGQTRLLRWSVPGIAHFFTMWGFFVLATVYIEAFGQLV
Rv0338c|M.tuberculosis_H37Rv LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
Mb0345c|M.bovis_AF2122/97 LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
MMAR_0611|M.marinum_M IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF
MUL_0574|M.ulcerans_Agy99 IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF
MAV_4817|M.avium_104 PGKRVWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
MLBr_02501|M.leprae_Br4923 LGTRIWTQITEVFGQRRLLQWSLPGLTHLFTMWGFFILLTVYIEAYGVLF
MSMEG_0690|M.smegmatis_MC2_155 LQKRITTQITEVFGQTRLLRWSVPGIAHFFTMWGFFVLASVYLEAYGVLF
MAB_4293|M.abscessus_ATCC_1997 FLPRLKQLIVEVVAHTRMNKFRTVGWAHWLVMVGFLGGFPLYFESYGQTF
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK DHDFHIPLIGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR
Mvan_0619|M.vanbaalenii_PYR-1 DHDFHIPLVGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR
Rv0338c|M.tuberculosis_H37Rv EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR
Mb0345c|M.bovis_AF2122/97 EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR
MMAR_0611|M.marinum_M VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR
MUL_0574|M.ulcerans_Agy99 VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR
MAV_4817|M.avium_104 QDNFHIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSR
MLBr_02501|M.leprae_Br4923 QPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKEYGRKSR
MSMEG_0690|M.smegmatis_MC2_155 DPEFHIPFIGRWPVLGFLQDFFAVAVLLGIIVFAIIRVVREPKKIGRDSR
MAB_4293|M.abscessus_ATCC_1997 NPEFHWPIIGDTFLWHLWDELLGIGTVIGIVTLIIIRQLNHPRKPERLSR
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK FYGSHTGGAWLILFMIFNVIWTYALVRGAAAV--VGNLPYGNGAFFSQFM
Mvan_0619|M.vanbaalenii_PYR-1 FYGSHTGGAWLILFMIFNVIWTYALVRGAGAN--TGALPYGNGAFFSQFM
Rv0338c|M.tuberculosis_H37Rv FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF
Mb0345c|M.bovis_AF2122/97 FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF
MMAR_0611|M.marinum_M FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF
MUL_0574|M.ulcerans_Agy99 FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF
MAV_4817|M.avium_104 FYGSHTGGAWLVLFMIFNVIWTYVLVRGSAVN--NGTLPYGKGAFLSQLF
MLBr_02501|M.leprae_Br4923 FYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAI
MSMEG_0690|M.smegmatis_MC2_155 FYGSHTGGAWEILFMIFLVIATYALFRGAAVNTLGERFPYQSGAFFSDFM
MAB_4293|M.abscessus_ATCC_1997 FGGSNFFAAYTIEMIVLVEGLGMVLVKSGKIATFHNSHPSSD--FFTMNV
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK GWIMRPLGHTANEWIETIALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT
Mvan_0619|M.vanbaalenii_PYR-1 GWIMHPLGEPANEWIETLALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT
Rv0338c|M.tuberculosis_H37Rv GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT
Mb0345c|M.bovis_AF2122/97 GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT
MMAR_0611|M.marinum_M GAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT
MUL_0574|M.ulcerans_Agy99 AAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT
MAV_4817|M.avium_104 GAILRPLGQPANEYIETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINVI
MLBr_02501|M.leprae_Br4923 AAVLYPLGQGANQIIETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVT
MSMEG_0690|M.smegmatis_MC2_155 AWILRPLGATANMWIETVALMGHIGVMLVFLLIVLHSKHLHIGLAPINVT
MAB_4293|M.abscessus_ATCC_1997 AQLLPESPIMVSVFAFIKMMSGGLFLLLVGRKLVWG-VAWHRFAAFFNIY
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK FKRLPNG---LGPLLPVESKGELVDFEDP-AEDAVLGRGKIEDFTWKGYL
Mvan_0619|M.vanbaalenii_PYR-1 FKRMPNA---LGPLLPVEYKGELVDFEDP-AEDAVLGRGKIEDFTWKAYL
Rv0338c|M.tuberculosis_H37Rv FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML
Mb0345c|M.bovis_AF2122/97 FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML
MMAR_0611|M.marinum_M FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML
MUL_0574|M.ulcerans_Agy99 FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML
MAV_4817|M.avium_104 FKRLPNG---LGPLLPIEYDGKPIDFENP-PDDAVFGRGKVEDFSWKAML
MLBr_02501|M.leprae_Br4923 FKRLPDG---LGPLMPMESDGEPINFEDP-SEDAVFGRGKIEDFTWKAML
MSMEG_0690|M.smegmatis_MC2_155 FKRLPNG---LGPLLPMESNGEYIDFEDP-AEDAVFGKGKIEDFTWKGYL
MAB_4293|M.abscessus_ATCC_1997 FKRNADGSVALGAAKPMMSGGKVLEMESADPDVDAFGAGKVEDFSWKDLL
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYFLDGKES
Mvan_0619|M.vanbaalenii_PYR-1 DMTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHLFAKAPYILGDKET
Rv0338c|M.tuberculosis_H37Rv DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK--
Mb0345c|M.bovis_AF2122/97 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK--
MMAR_0611|M.marinum_M DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MUL_0574|M.ulcerans_Agy99 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MAV_4817|M.avium_104 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQS
MLBr_02501|M.leprae_Br4923 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MSMEG_0690|M.smegmatis_MC2_155 DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYILGEKPS
MAB_4293|M.abscessus_ATCC_1997 DVTTCTECGRCQSQCPAWNTGKPLSPKLLITSLRDHTYAKAPYLLAGE--
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK PLENTPEGGLGEELRGEKHSEKHSHEHVPESGFERIPADSPLQATRPLVG
Mvan_0619|M.vanbaalenii_PYR-1 PLENTPEGGLGEELRGEKQSEEHSHEHVPESGFERIMGSGPEQATRPLVG
Rv0338c|M.tuberculosis_H37Rv --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG
Mb0345c|M.bovis_AF2122/97 --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG
MMAR_0611|M.marinum_M --TADPLEGLDLETAAE------EGHHVPESGFGRVPGDGPEQAARPLVG
MUL_0574|M.ulcerans_Agy99 --TADLLEGLDLETAAG------EGHHVPESGFGRVPGDGPEQAARPLVG
MAV_4817|M.avium_104 PLESTPEGGVGEELSGEK---HAEAHHVPESGFGRVMGSGPEQATRPLVG
MLBr_02501|M.leprae_Br4923 --TAEKLEGLNLETTKD------KSRHVPESGFGRVPGHGPEQATRPLVG
MSMEG_0690|M.smegmatis_MC2_155 PLESTPEGGLGEKARGEKHEQKHAHDHVPESGFERILGSGPEQALRPLVG
MAB_4293|M.abscessus_ATCC_1997 -------------------------------DKSKLSEAEIAEGERQLVG
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK TLEEGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Mvan_0619|M.vanbaalenii_PYR-1 TLEQGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Rv0338c|M.tuberculosis_H37Rv TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
Mb0345c|M.bovis_AF2122/97 TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
MMAR_0611|M.marinum_M TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
MUL_0574|M.ulcerans_Agy99 TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
MAV_4817|M.avium_104 TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
MLBr_02501|M.leprae_Br4923 TAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIIDMRRYQVMMESEF
MSMEG_0690|M.smegmatis_MC2_155 TEEQGGVIDPDVLWSCTNCGACVEQCPVDIEHIDHIVDMRRYQVMVESEF
MAB_4293|M.abscessus_ATCC_1997 G--EGAVIDHEVLWSCTTCGACVEQCPVDIEHVDHIIDMRRYQVLIESEF
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK PGELGVLFKNLETKGNPWGQNSKDRTNWIDEVDFDVPVFGKDVDSFEGYE
Mvan_0619|M.vanbaalenii_PYR-1 PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGKDVESFDGFE
Rv0338c|M.tuberculosis_H37Rv PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE
Mb0345c|M.bovis_AF2122/97 PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE
MMAR_0611|M.marinum_M PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MUL_0574|M.ulcerans_Agy99 PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MAV_4817|M.avium_104 PSELSVLFKNLETKANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MLBr_02501|M.leprae_Br4923 PSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYE
MSMEG_0690|M.smegmatis_MC2_155 PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGEDVDSFDGFE
MAB_4293|M.abscessus_ATCC_1997 PGELAGLFKNLENKGNPWGQNAKDRLNWIEEVDFDVPVFGQDVDSFADFE
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK YLFWVGCAGAYEDRAKKTTKAVAELLSAAGVKYLVLGEGETCNGDSARRS
Mvan_0619|M.vanbaalenii_PYR-1 YLFWVGCAGAYEDRAKKTTKAVAELLAAAGVKYLVLGEGETCNGDSARRS
Rv0338c|M.tuberculosis_H37Rv YLFWVGCAGAYDDKAKKTTKAVAELLAVARVKYLVLGAGETCNGDSARRS
Mb0345c|M.bovis_AF2122/97 YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS
MMAR_0611|M.marinum_M YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
MUL_0574|M.ulcerans_Agy99 YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
MAV_4817|M.avium_104 YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS
MLBr_02501|M.leprae_Br4923 YLFWVGCAGAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRS
MSMEG_0690|M.smegmatis_MC2_155 YLFWVGCAGAYEDRAKKTTKAVAELLATAGVKFLVLGTGETCTGDSARRS
MAB_4293|M.abscessus_ATCC_1997 YLFWVGCAGAYEDRAKKTTKAVAELLALAGTKFLVLGADETCTGDSARRA
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK GNEFLFQQLAAQNVETLNDLFSGIERVDRKVVVTCPHCFNTLGREYPQVG
Mvan_0619|M.vanbaalenii_PYR-1 GNEFLFQQLAAQNVETLGELFEGVERVDRKVVVTCPHCFNTLGREYPQLG
Rv0338c|M.tuberculosis_H37Rv GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG
Mb0345c|M.bovis_AF2122/97 GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG
MMAR_0611|M.marinum_M GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
MUL_0574|M.ulcerans_Agy99 GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
MAV_4817|M.avium_104 GNEFLFQQLAAQAVETLDGVFEGVETVDRKIVVTCPHCFNTLGREYRQLG
MLBr_02501|M.leprae_Br4923 GNEFLFQQLAAQAVEILDGLFEGVNSVDRKIVVTCPHCFNTIGKEYRQLG
MSMEG_0690|M.smegmatis_MC2_155 GNEFLFQQLAAQNVETINELFEGVETVDRKIVVTCPHCFNTIGREYPQLG
MAB_4293|M.abscessus_ATCC_1997 GNEFLFQQLAMQNIELLNSVFEGVEQKQRKIVVTCAHCFNALGNEYPQVG
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK GNYTVLHHTQLLNRLVRDKKLVPVKSTDGSPNGQDITYHDPCYLGRHNKE
Mvan_0619|M.vanbaalenii_PYR-1 GNYTVLHHTQLLNRLVRDKKLVPVKSTD---NGQDITYHDPCYLGRHNKE
Rv0338c|M.tuberculosis_H37Rv ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKA
Mb0345c|M.bovis_AF2122/97 ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKV
MMAR_0611|M.marinum_M SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV
MUL_0574|M.ulcerans_Agy99 SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV
MAV_4817|M.avium_104 ANYTVLHHTQLLNRLIRDNKLVPVTPVS-----QDITYHDPCYLGRHNKV
MLBr_02501|M.leprae_Br4923 GNYTVLHHTQLLNWLVHDKKLVPVTPVS-----QDITYHDPCYLGRHNKV
MSMEG_0690|M.smegmatis_MC2_155 ANYSVVHHTQLLNRLVRDKKLVPVKSVSEQ-NGQPVTYHDPCFLGRHNKV
MAB_4293|M.abscessus_ATCC_1997 GDYQVVHHTQLLNRLVRDKKLVPVAPVS-----QDVTYHDPCYLGRHNKV
TH_2670|M.thermoresistible__bu -----------MFHVKHGRPQSPSIPDG----------------------
: : :.. * . .
Mflv_0278|M.gilvum_PYR-GCK YSAPRELIGASGAKLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT
Mvan_0619|M.vanbaalenii_PYR-1 YSAPRELIGASGATLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT
Rv0338c|M.tuberculosis_H37Rv YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV
Mb0345c|M.bovis_AF2122/97 YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV
MMAR_0611|M.marinum_M YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MUL_0574|M.ulcerans_Agy99 YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MAV_4817|M.avium_104 YEAPRELIGAAGANLTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MLBr_02501|M.leprae_Br4923 YEAPRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MSMEG_0690|M.smegmatis_MC2_155 YEAPRELVEASGVTLKEMPRHADRGLCCGAGGARMWMEEHIGKRVNVERT
MAB_4293|M.abscessus_ATCC_1997 YTAPRELIGASGAAITEMPRHGERSMCCGAGGARMWMEEQLGKRINIDRV
TH_2670|M.thermoresistible__bu --IPPXXXXADGEKTGGAP--AAKGLSIAAG-------------------
* * * * . :.:. .**
Mflv_0278|M.gilvum_PYR-GCK EEAIDTGASAIATGCPFCRVMMTDGVDDVSATRDIEKVEVLDVAQLLLGS
Mvan_0619|M.vanbaalenii_PYR-1 EEAIDTGASAIATGCPFCRVMMTDGVDDVSAAREIEKVEVLDVAQLLLGS
Rv0338c|M.tuberculosis_H37Rv DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
Mb0345c|M.bovis_AF2122/97 DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MMAR_0611|M.marinum_M DEALATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MUL_0574|M.ulcerans_Agy99 DEAVATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MAV_4817|M.avium_104 DEALATGAATVATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGS
MLBr_02501|M.leprae_Br4923 DEALATNATTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MSMEG_0690|M.smegmatis_MC2_155 EEAMDT-ASTIATGCPFCRVMITDGVDDVAASRNVEKAEVLDVAQLLLNS
MAB_4293|M.abscessus_ATCC_1997 DEALSTPASKIATGCPFCRVMLTDGVTARDD---SAAVEVVDVAQLLLES
TH_2670|M.thermoresistible__bu --AKRPGAKKTAPAG-----------------------------------
* . * *..
Mflv_0278|M.gilvum_PYR-GCK LDKST---FTLPEKGTAAKESEERAARIAAEAPAEVEAEEPE-----AAP
Mvan_0619|M.vanbaalenii_PYR-1 LDQSS---FTLPEKGTAAKEAEERAARVAAQAPAKAEESAIETEAEAKTA
Rv0338c|M.tuberculosis_H37Rv LDHDK---AQLPAKGTAAKQAQERAPKAAPKA------------------
Mb0345c|M.bovis_AF2122/97 LDHDK---AQLPAKGTAAKQAQERAPKAAPKA------------------
MMAR_0611|M.marinum_M LDREK---ATLPEKGTAAKEAEKRA-KAAPKA------------------
MUL_0574|M.ulcerans_Agy99 LDREK---ATLPEKGTAAKEAEKRA-KTAPKA------------------
MAV_4817|M.avium_104 LEYDK---ATLPEKGTAAKEAEKRAAQAPKAT------------------
MLBr_02501|M.leprae_Br4923 LDYDK---AKLPAKGTAAAEITKTAGLSPAKP------------------
MSMEG_0690|M.smegmatis_MC2_155 LDTSK---VTLPEKGTAAKESEKRAAARAEAE------------------
MAB_4293|M.abscessus_ATCC_1997 VGRTEDIRKALPAKGTAAAAAAERAATKTAEPEPVVAEEEAP----ATTK
TH_2670|M.thermoresistible__bu ----------QADSGTAETET-----------------------------
. .***
Mflv_0278|M.gilvum_PYR-GCK AEEAAPAEAKAGTATETKPVTGLGVAGGAKRPGAKK-TAAAPAEDKPAAA
Mvan_0619|M.vanbaalenii_PYR-1 AEPAEAAKSTAAADTESKPVTGLGLAGGAKRPGAKKPAAAEPAEDKP--A
Rv0338c|M.tuberculosis_H37Rv AAPVTPVEAPAEAP------------------------------------
Mb0345c|M.bovis_AF2122/97 AAPVTPVEAPAEAP------------------------------------
MMAR_0611|M.marinum_M AAPAAPAPAPAEAPAK---------------------AAEAPAAATAASP
MUL_0574|M.ulcerans_Agy99 AAPAAPAPAPAEAPAK---------------------AAEASAAATAASP
MAV_4817|M.avium_104 ATVEAPAKETTKEPAE---------------------AAP-KAEAAPAAP
MLBr_02501|M.leprae_Br4923 TESEAPAPE-----------------------------------------
MSMEG_0690|M.smegmatis_MC2_155 AKAEAAAPPVEEAAPE---------------------AEAPAAPAAGGAE
MAB_4293|M.abscessus_ATCC_1997 AEAAAPAAEAKPVSGLGMATGAKRPGAKKTAAENSTAEASTATPTAEAAP
TH_2670|M.thermoresistible__bu -----PKPE-----------------------------------------
.
Mflv_0278|M.gilvum_PYR-GCK AAPAKGLGIAGGAKRPGAKKAAPAAEAAPAADAPAKAEPEVKGLGIAGGA
Mvan_0619|M.vanbaalenii_PYR-1 PAPAKGLGIAGGAKRPGAKKAAPAAGTTP---------------------
Rv0338c|M.tuberculosis_H37Rv --------------------QAPAPAAP----------------------
Mb0345c|M.bovis_AF2122/97 --------------------QAPAPAAP----------------------
MMAR_0611|M.marinum_M AAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKK
MUL_0574|M.ulcerans_Agy99 AAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKK
MAV_4817|M.avium_104 AAPVKGLGIAGGAKRPGAKKSAPAAEAKTEAPAEAKTEAP----------
MLBr_02501|M.leprae_Br4923 -------------------KSTQAAAS-----------------------
MSMEG_0690|M.smegmatis_MC2_155 AKPVTGLGMAGAAKRPGAKKAAPAAEASAAPAAAPAPAKG-----LGLAG
MAB_4293|M.abscessus_ATCC_1997 AAPVKGLGMAAGAKRPGAKKATAETSAATPPAASASPPAS----------
TH_2670|M.thermoresistible__bu --------------------------------------------------
Mflv_0278|M.gilvum_PYR-GCK KRPGAKKAAPAVEAAPAADAPAKAEPEAKGLGIAGGAKRPGAKKASGTVV
Mvan_0619|M.vanbaalenii_PYR-1 --------APAAESAAAAEP-AKAEPEVKGLGIAGGAKRPGAKKQAAPAA
Rv0338c|M.tuberculosis_H37Rv ------------------------AAPVKGLGMAAGAKRPGAKKAAP---
Mb0345c|M.bovis_AF2122/97 ------------------------AAPVKGLGMAAGAKRPGAKKAAP---
MMAR_0611|M.marinum_M PGAKKAAAPTGETKPAEAAAPAAPAAPVKGLGMASGAKRPGAKKAAPPAA
MUL_0574|M.ulcerans_Agy99 PGAKKAAAPTGETKPAEAAAP---AAPVKGLGMASGAKRPGAKKAAPPAA
MAV_4817|M.avium_104 ------------------------AAPAKGLGIAAGAKRPGAKKSAPAAQ
MLBr_02501|M.leprae_Br4923 ------------------------AAPAKGIRLAAGAKQPDAKKPVSQTT
MSMEG_0690|M.smegmatis_MC2_155 GAKRPGAKKAAAPAAEAPAAPASDAPPVKGLGLAGGAKRPGAKKTAAAAP
MAB_4293|M.abscessus_ATCC_1997 ---------------QAPAAAAAPAPPVKGLGMAAGAKRPGAKKTAPAAP
TH_2670|M.thermoresistible__bu -------------------------PEVKGLGIAAGARRPGARKATSKAD
. .**: :*.**::*.*:*
Mflv_0278|M.gilvum_PYR-GCK QPPNVDPDKAEAGTESAGTADSDRGLDDAPKPEPEVKGLGIAAGARRPGA
Mvan_0619|M.vanbaalenii_PYR-1 --PAAAAPAATPAPEAP--AQPEAAAAAPAKPEPEVKGLGIAAGARRPGA
Rv0338c|M.tuberculosis_H37Rv ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA
Mb0345c|M.bovis_AF2122/97 ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA
MMAR_0611|M.marinum_M AAPEAAATASAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA
MUL_0574|M.ulcerans_Agy99 AAPEAAATAPAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA
MAV_4817|M.avium_104 APKTEAPKTEAPKTEAKTEAAGEAKTEAPAAPAAPVKGLGIAAGAKRPGA
MLBr_02501|M.leprae_Br4923 S----------------------AKATEAPAATVPVKGLGIAGGAKRPGA
MSMEG_0690|M.smegmatis_MC2_155 AEKPAATEAP-------------EASATPAAPAAPVKGLGLAAGAKRPGA
MAB_4293|M.abscessus_ATCC_1997 AAPAPEAAAVPSESE------APTATETSAVAEPPVKGLGIAAGARRPGA
TH_2670|M.thermoresistible__bu TARADTAKADTADT-------AAAXTQAPAQPEPEVKGLAIAPGARRPGA
.. . ****.:* **:****
Mflv_0278|M.gilvum_PYR-GCK KKKAPAAAPDS----------------APAAAPES---------------
Mvan_0619|M.vanbaalenii_PYR-1 KKAPAAPAAESTSAPAESAPAPAESAPAPAATPEP---------------
Rv0338c|M.tuberculosis_H37Rv KKTPPPAPG-LAEPAAQ---------PQPEAKPQP---------------
Mb0345c|M.bovis_AF2122/97 KKTPPPAPG-LAEPAAQ---------PQPEAKPQP---------------
MMAR_0611|M.marinum_M KKAPARAEAPAAAAPAQ---------PEPEATPEP---------------
MUL_0574|M.ulcerans_Agy99 KKAPARAEAPSAAAPAQ---------PEPEATPEP---------------
MAV_4817|M.avium_104 KKAAPKAEAPKAEAEAAKAEAPKPEAPKAEAESKP---------------
MLBr_02501|M.leprae_Br4923 KKSPD-----QAETPAP---------TESKSEAKP---------------
MSMEG_0690|M.smegmatis_MC2_155 KKTAAAPAEKPAAAETEAPAPAETAAPAEPAKPEPPVVGLGIAAGARRPG
MAB_4293|M.abscessus_ATCC_1997 KKAAPATESAPEP-------------AQPATAPEP---------------
TH_2670|M.thermoresistible__bu KKAPATPAPAPAEPAAP---------KQPEAS------------------
** . :
Mflv_0278|M.gilvum_PYR-GCK ------------APAAPSSNGSDSS-----KGDDRVVGDEAPVKGLGIAK
Mvan_0619|M.vanbaalenii_PYR-1 ------------EPAPEAPSSGASD-----NGDTRVVGDEPPVKGLGIAK
Rv0338c|M.tuberculosis_H37Rv ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR
Mb0345c|M.bovis_AF2122/97 ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR
MMAR_0611|M.marinum_M ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR
MUL_0574|M.ulcerans_Agy99 ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR
MAV_4817|M.avium_104 ------------EPAKPSNGEGGS-----------SKPSQPPVKGLGIAR
MLBr_02501|M.leprae_Br4923 ------------EPSDHADG----N----------PAPPTAPVKRLGITR
MSMEG_0690|M.smegmatis_MC2_155 AKKAAAKPAAAPAPAAEKPAEQAAEPEKPAEKPAEPEKPEPPVVGLGIKP
MAB_4293|M.abscessus_ATCC_1997 -----------TEPATSAPKDEAPET---------SSTPEPPVKGLGIAP
TH_2670|M.thermoresistible__bu ------------DTAGQAEQAGSAE-----------EKPQPPVKGLGIAK
.: .** **:
Mflv_0278|M.gilvum_PYR-GCK GARRPGKR-
Mvan_0619|M.vanbaalenii_PYR-1 GARRPGKR-
Rv0338c|M.tuberculosis_H37Rv GARPPGKR-
Mb0345c|M.bovis_AF2122/97 GARPPGKR-
MMAR_0611|M.marinum_M GARPPGKR-
MUL_0574|M.ulcerans_Agy99 GARPPGKR-
MAV_4817|M.avium_104 GARPPGKR-
MLBr_02501|M.leprae_Br4923 SARPPGKH-
MSMEG_0690|M.smegmatis_MC2_155 GAKRPGKR-
MAB_4293|M.abscessus_ATCC_1997 GARRPGRRN
TH_2670|M.thermoresistible__bu GARPPGKKR
.*: **::