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M. leprae Br4923 MLBr_02501 (-)

annotation: putative iron-sulphur-binding reductase
coordinates: 2980048 - 2982690
length: 880

VTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQPANGRTDELGTRIWTQITEVFGQRRLLQWSLP
GLTHLFTMWGFFILLTVYIEAYGVLFQPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKE
YGRKSRFYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAIAAVLYPLGQGANQI
IETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVTFKRLPDGLGPLMPMESDGEPINFEDPSEDAVFGR
GKIEDFTWKAMLDFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTAEKLEGLNL
ETTKDKSRHVPESGFGRVPGHGPEQATRPLVGTAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIID
MRRYQVMMESEFPSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCA
GAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRSGNEFLFQQLAAQAVEILDGLFEGVNSVD
RKIVVTCPHCFNTIGKEYRQLGGNYTVLHHTQLLNWLVHDKKLVPVTPVSQDITYHDPCYLGRHNKVYEA
PRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALATNATTIATACPFCRVMVT
DGVNDRQEEAGRSGVEVLDVAQVLLGSLDYDKAKLPAKGTAAAEITKTAGLSPAKPTESEAPAPEKSTQA
AASAAPAKGIRLAAGAKQPDAKKPVSQTTSAKATEAPAATVPVKGLGIAGGAKRPGAKKSPDQAETPAPT
ESKSEAKPEPSDHADGNPAPPTAPVKRLGITRSARPPGKH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_02501--100% (880)putative iron-sulphur-binding reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0345c-0.078.39% (893) putative iron-sulfur-binding reductase
M. gilvum PYR-GCKMflv_0278-0.066.48% (910) hypothetical protein Mflv_0278
M. tuberculosis H37RvRv0338c-0.078.16% (893) iron-sulfur-binding reductase
M. abscessus ATCC 19977MAB_4293-0.051.33% (904) putative Fe-S oxidoreductase
M. marinum MMMAR_0611-0.070.89% (986) iron-sulphur-binding reductase
M. avium 104MAV_4817-0.074.89% (908) ferredoxin, 4Fe-4S
M. smegmatis MC2 155MSMEG_0690-0.067.34% (940) iron-sulfur cluster-binding protein
M. thermoresistible (build 8)TH_2670-1e-1939.87% (158) PUTATIVE -
M. ulcerans Agy99MUL_0574-0.073.81% (924) iron-sulphur-binding reductase
M. vanbaalenii PYR-1Mvan_0619-0.067.32% (912) hypothetical protein Mvan_0619

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0278|M.gilvum_PYR-GCK          -METQMLIRIIAGVLMLAVVGVFAAKRVLWLTKLIRSGQPLSEGNNRKDH
Mvan_0619|M.vanbaalenii_PYR-1       -MDTQMLIRIVVGVLMIAVVGVFAVKRVLWLTTLIRSGQPMSEGNNRKDH
Mb0345c|M.bovis_AF2122/97           -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN
Rv0338c|M.tuberculosis_H37Rv        -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN
MMAR_0611|M.marinum_M               -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD
MUL_0574|M.ulcerans_Agy99           -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD
MAV_4817|M.avium_104                -MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGK---PAPGHTDD
MLBr_02501|M.leprae_Br4923          -MTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQ---PANGRTDE
MSMEG_0690|M.smegmatis_MC2_155      MAHTLEVSRLIIGLLMTAIVLVFAAKRVLWLTKLIRSGQKTLDENGRKND
MAB_4293|M.abscessus_ATCC_1997      -MSTATITLGIIGVIFSLVAWGSFFGGVVKMVRVILSGQ---PDRTRFRP
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          LQKRITTQFEEVFGQTRLLRWSIPGIAHFFTMWGFFVLATVYLEAFGLLV
Mvan_0619|M.vanbaalenii_PYR-1       LKQRITTQFEEVFGQTRLLRWSVPGIAHFFTMWGFFVLATVYIEAFGQLV
Mb0345c|M.bovis_AF2122/97           LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
Rv0338c|M.tuberculosis_H37Rv        LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
MMAR_0611|M.marinum_M               IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF
MUL_0574|M.ulcerans_Agy99           IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF
MAV_4817|M.avium_104                PGKRVWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF
MLBr_02501|M.leprae_Br4923          LGTRIWTQITEVFGQRRLLQWSLPGLTHLFTMWGFFILLTVYIEAYGVLF
MSMEG_0690|M.smegmatis_MC2_155      LQKRITTQITEVFGQTRLLRWSVPGIAHFFTMWGFFVLASVYLEAYGVLF
MAB_4293|M.abscessus_ATCC_1997      FLPRLKQLIVEVVAHTRMNKFRTVGWAHWLVMVGFLGGFPLYFESYGQTF
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          DHDFHIPLIGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR
Mvan_0619|M.vanbaalenii_PYR-1       DHDFHIPLVGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR
Mb0345c|M.bovis_AF2122/97           EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR
Rv0338c|M.tuberculosis_H37Rv        EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR
MMAR_0611|M.marinum_M               VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR
MUL_0574|M.ulcerans_Agy99           VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR
MAV_4817|M.avium_104                QDNFHIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSR
MLBr_02501|M.leprae_Br4923          QPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKEYGRKSR
MSMEG_0690|M.smegmatis_MC2_155      DPEFHIPFIGRWPVLGFLQDFFAVAVLLGIIVFAIIRVVREPKKIGRDSR
MAB_4293|M.abscessus_ATCC_1997      NPEFHWPIIGDTFLWHLWDELLGIGTVIGIVTLIIIRQLNHPRKPERLSR
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          FYGSHTGGAWLILFMIFNVIWTYALVRGAAAV--VGNLPYGNGAFFSQFM
Mvan_0619|M.vanbaalenii_PYR-1       FYGSHTGGAWLILFMIFNVIWTYALVRGAGAN--TGALPYGNGAFFSQFM
Mb0345c|M.bovis_AF2122/97           FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF
Rv0338c|M.tuberculosis_H37Rv        FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF
MMAR_0611|M.marinum_M               FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF
MUL_0574|M.ulcerans_Agy99           FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF
MAV_4817|M.avium_104                FYGSHTGGAWLVLFMIFNVIWTYVLVRGSAVN--NGTLPYGKGAFLSQLF
MLBr_02501|M.leprae_Br4923          FYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAI
MSMEG_0690|M.smegmatis_MC2_155      FYGSHTGGAWEILFMIFLVIATYALFRGAAVNTLGERFPYQSGAFFSDFM
MAB_4293|M.abscessus_ATCC_1997      FGGSNFFAAYTIEMIVLVEGLGMVLVKSGKIATFHNSHPSSD--FFTMNV
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          GWIMRPLGHTANEWIETIALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT
Mvan_0619|M.vanbaalenii_PYR-1       GWIMHPLGEPANEWIETLALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT
Mb0345c|M.bovis_AF2122/97           GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT
Rv0338c|M.tuberculosis_H37Rv        GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT
MMAR_0611|M.marinum_M               GAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT
MUL_0574|M.ulcerans_Agy99           AAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT
MAV_4817|M.avium_104                GAILRPLGQPANEYIETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINVI
MLBr_02501|M.leprae_Br4923          AAVLYPLGQGANQIIETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVT
MSMEG_0690|M.smegmatis_MC2_155      AWILRPLGATANMWIETVALMGHIGVMLVFLLIVLHSKHLHIGLAPINVT
MAB_4293|M.abscessus_ATCC_1997      AQLLPESPIMVSVFAFIKMMSGGLFLLLVGRKLVWG-VAWHRFAAFFNIY
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          FKRLPNG---LGPLLPVESKGELVDFEDP-AEDAVLGRGKIEDFTWKGYL
Mvan_0619|M.vanbaalenii_PYR-1       FKRMPNA---LGPLLPVEYKGELVDFEDP-AEDAVLGRGKIEDFTWKAYL
Mb0345c|M.bovis_AF2122/97           FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML
Rv0338c|M.tuberculosis_H37Rv        FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML
MMAR_0611|M.marinum_M               FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML
MUL_0574|M.ulcerans_Agy99           FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML
MAV_4817|M.avium_104                FKRLPNG---LGPLLPIEYDGKPIDFENP-PDDAVFGRGKVEDFSWKAML
MLBr_02501|M.leprae_Br4923          FKRLPDG---LGPLMPMESDGEPINFEDP-SEDAVFGRGKIEDFTWKAML
MSMEG_0690|M.smegmatis_MC2_155      FKRLPNG---LGPLLPMESNGEYIDFEDP-AEDAVFGKGKIEDFTWKGYL
MAB_4293|M.abscessus_ATCC_1997      FKRNADGSVALGAAKPMMSGGKVLEMESADPDVDAFGAGKVEDFSWKDLL
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYFLDGKES
Mvan_0619|M.vanbaalenii_PYR-1       DMTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHLFAKAPYILGDKET
Mb0345c|M.bovis_AF2122/97           DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK--
Rv0338c|M.tuberculosis_H37Rv        DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK--
MMAR_0611|M.marinum_M               DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MUL_0574|M.ulcerans_Agy99           DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MAV_4817|M.avium_104                DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQS
MLBr_02501|M.leprae_Br4923          DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK--
MSMEG_0690|M.smegmatis_MC2_155      DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYILGEKPS
MAB_4293|M.abscessus_ATCC_1997      DVTTCTECGRCQSQCPAWNTGKPLSPKLLITSLRDHTYAKAPYLLAGE--
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          PLENTPEGGLGEELRGEKHSEKHSHEHVPESGFERIPADSPLQATRPLVG
Mvan_0619|M.vanbaalenii_PYR-1       PLENTPEGGLGEELRGEKQSEEHSHEHVPESGFERIMGSGPEQATRPLVG
Mb0345c|M.bovis_AF2122/97           --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG
Rv0338c|M.tuberculosis_H37Rv        --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG
MMAR_0611|M.marinum_M               --TADPLEGLDLETAAE------EGHHVPESGFGRVPGDGPEQAARPLVG
MUL_0574|M.ulcerans_Agy99           --TADLLEGLDLETAAG------EGHHVPESGFGRVPGDGPEQAARPLVG
MAV_4817|M.avium_104                PLESTPEGGVGEELSGEK---HAEAHHVPESGFGRVMGSGPEQATRPLVG
MLBr_02501|M.leprae_Br4923          --TAEKLEGLNLETTKD------KSRHVPESGFGRVPGHGPEQATRPLVG
MSMEG_0690|M.smegmatis_MC2_155      PLESTPEGGLGEKARGEKHEQKHAHDHVPESGFERILGSGPEQALRPLVG
MAB_4293|M.abscessus_ATCC_1997      -------------------------------DKSKLSEAEIAEGERQLVG
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          TLEEGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Mvan_0619|M.vanbaalenii_PYR-1       TLEQGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
Mb0345c|M.bovis_AF2122/97           TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
Rv0338c|M.tuberculosis_H37Rv        TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
MMAR_0611|M.marinum_M               TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
MUL_0574|M.ulcerans_Agy99           TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF
MAV_4817|M.avium_104                TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF
MLBr_02501|M.leprae_Br4923          TAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIIDMRRYQVMMESEF
MSMEG_0690|M.smegmatis_MC2_155      TEEQGGVIDPDVLWSCTNCGACVEQCPVDIEHIDHIVDMRRYQVMVESEF
MAB_4293|M.abscessus_ATCC_1997      G--EGAVIDHEVLWSCTTCGACVEQCPVDIEHVDHIIDMRRYQVLIESEF
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          PGELGVLFKNLETKGNPWGQNSKDRTNWIDEVDFDVPVFGKDVDSFEGYE
Mvan_0619|M.vanbaalenii_PYR-1       PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGKDVESFDGFE
Mb0345c|M.bovis_AF2122/97           PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE
Rv0338c|M.tuberculosis_H37Rv        PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE
MMAR_0611|M.marinum_M               PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MUL_0574|M.ulcerans_Agy99           PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MAV_4817|M.avium_104                PSELSVLFKNLETKANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE
MLBr_02501|M.leprae_Br4923          PSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYE
MSMEG_0690|M.smegmatis_MC2_155      PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGEDVDSFDGFE
MAB_4293|M.abscessus_ATCC_1997      PGELAGLFKNLENKGNPWGQNAKDRLNWIEEVDFDVPVFGQDVDSFADFE
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          YLFWVGCAGAYEDRAKKTTKAVAELLSAAGVKYLVLGEGETCNGDSARRS
Mvan_0619|M.vanbaalenii_PYR-1       YLFWVGCAGAYEDRAKKTTKAVAELLAAAGVKYLVLGEGETCNGDSARRS
Mb0345c|M.bovis_AF2122/97           YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS
Rv0338c|M.tuberculosis_H37Rv        YLFWVGCAGAYDDKAKKTTKAVAELLAVARVKYLVLGAGETCNGDSARRS
MMAR_0611|M.marinum_M               YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
MUL_0574|M.ulcerans_Agy99           YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS
MAV_4817|M.avium_104                YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS
MLBr_02501|M.leprae_Br4923          YLFWVGCAGAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRS
MSMEG_0690|M.smegmatis_MC2_155      YLFWVGCAGAYEDRAKKTTKAVAELLATAGVKFLVLGTGETCTGDSARRS
MAB_4293|M.abscessus_ATCC_1997      YLFWVGCAGAYEDRAKKTTKAVAELLALAGTKFLVLGADETCTGDSARRA
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          GNEFLFQQLAAQNVETLNDLFSGIERVDRKVVVTCPHCFNTLGREYPQVG
Mvan_0619|M.vanbaalenii_PYR-1       GNEFLFQQLAAQNVETLGELFEGVERVDRKVVVTCPHCFNTLGREYPQLG
Mb0345c|M.bovis_AF2122/97           GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG
Rv0338c|M.tuberculosis_H37Rv        GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG
MMAR_0611|M.marinum_M               GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
MUL_0574|M.ulcerans_Agy99           GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG
MAV_4817|M.avium_104                GNEFLFQQLAAQAVETLDGVFEGVETVDRKIVVTCPHCFNTLGREYRQLG
MLBr_02501|M.leprae_Br4923          GNEFLFQQLAAQAVEILDGLFEGVNSVDRKIVVTCPHCFNTIGKEYRQLG
MSMEG_0690|M.smegmatis_MC2_155      GNEFLFQQLAAQNVETINELFEGVETVDRKIVVTCPHCFNTIGREYPQLG
MAB_4293|M.abscessus_ATCC_1997      GNEFLFQQLAMQNIELLNSVFEGVEQKQRKIVVTCAHCFNALGNEYPQVG
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          GNYTVLHHTQLLNRLVRDKKLVPVKSTDGSPNGQDITYHDPCYLGRHNKE
Mvan_0619|M.vanbaalenii_PYR-1       GNYTVLHHTQLLNRLVRDKKLVPVKSTD---NGQDITYHDPCYLGRHNKE
Mb0345c|M.bovis_AF2122/97           ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKV
Rv0338c|M.tuberculosis_H37Rv        ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKA
MMAR_0611|M.marinum_M               SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV
MUL_0574|M.ulcerans_Agy99           SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV
MAV_4817|M.avium_104                ANYTVLHHTQLLNRLIRDNKLVPVTPVS-----QDITYHDPCYLGRHNKV
MLBr_02501|M.leprae_Br4923          GNYTVLHHTQLLNWLVHDKKLVPVTPVS-----QDITYHDPCYLGRHNKV
MSMEG_0690|M.smegmatis_MC2_155      ANYSVVHHTQLLNRLVRDKKLVPVKSVSEQ-NGQPVTYHDPCFLGRHNKV
MAB_4293|M.abscessus_ATCC_1997      GDYQVVHHTQLLNRLVRDKKLVPVAPVS-----QDVTYHDPCYLGRHNKV
TH_2670|M.thermoresistible__bu      -----------MFHVKHGRPQSPSIPDG----------------------
                                               :  : :..   *  . .                      

Mflv_0278|M.gilvum_PYR-GCK          YSAPRELIGASGAKLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT
Mvan_0619|M.vanbaalenii_PYR-1       YSAPRELIGASGATLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT
Mb0345c|M.bovis_AF2122/97           YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV
Rv0338c|M.tuberculosis_H37Rv        YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV
MMAR_0611|M.marinum_M               YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MUL_0574|M.ulcerans_Agy99           YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MAV_4817|M.avium_104                YEAPRELIGAAGANLTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MLBr_02501|M.leprae_Br4923          YEAPRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV
MSMEG_0690|M.smegmatis_MC2_155      YEAPRELVEASGVTLKEMPRHADRGLCCGAGGARMWMEEHIGKRVNVERT
MAB_4293|M.abscessus_ATCC_1997      YTAPRELIGASGAAITEMPRHGERSMCCGAGGARMWMEEQLGKRINIDRV
TH_2670|M.thermoresistible__bu      --IPPXXXXADGEKTGGAP--AAKGLSIAAG-------------------
                                       *     * *      *  . :.:. .**                   

Mflv_0278|M.gilvum_PYR-GCK          EEAIDTGASAIATGCPFCRVMMTDGVDDVSATRDIEKVEVLDVAQLLLGS
Mvan_0619|M.vanbaalenii_PYR-1       EEAIDTGASAIATGCPFCRVMMTDGVDDVSAAREIEKVEVLDVAQLLLGS
Mb0345c|M.bovis_AF2122/97           DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
Rv0338c|M.tuberculosis_H37Rv        DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MMAR_0611|M.marinum_M               DEALATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MUL_0574|M.ulcerans_Agy99           DEAVATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MAV_4817|M.avium_104                DEALATGAATVATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGS
MLBr_02501|M.leprae_Br4923          DEALATNATTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS
MSMEG_0690|M.smegmatis_MC2_155      EEAMDT-ASTIATGCPFCRVMITDGVDDVAASRNVEKAEVLDVAQLLLNS
MAB_4293|M.abscessus_ATCC_1997      DEALSTPASKIATGCPFCRVMLTDGVTARDD---SAAVEVVDVAQLLLES
TH_2670|M.thermoresistible__bu      --AKRPGAKKTAPAG-----------------------------------
                                      *  . *   *..                                    

Mflv_0278|M.gilvum_PYR-GCK          LDKST---FTLPEKGTAAKESEERAARIAAEAPAEVEAEEPE-----AAP
Mvan_0619|M.vanbaalenii_PYR-1       LDQSS---FTLPEKGTAAKEAEERAARVAAQAPAKAEESAIETEAEAKTA
Mb0345c|M.bovis_AF2122/97           LDHDK---AQLPAKGTAAKQAQERAPKAAPKA------------------
Rv0338c|M.tuberculosis_H37Rv        LDHDK---AQLPAKGTAAKQAQERAPKAAPKA------------------
MMAR_0611|M.marinum_M               LDREK---ATLPEKGTAAKEAEKRA-KAAPKA------------------
MUL_0574|M.ulcerans_Agy99           LDREK---ATLPEKGTAAKEAEKRA-KTAPKA------------------
MAV_4817|M.avium_104                LEYDK---ATLPEKGTAAKEAEKRAAQAPKAT------------------
MLBr_02501|M.leprae_Br4923          LDYDK---AKLPAKGTAAAEITKTAGLSPAKP------------------
MSMEG_0690|M.smegmatis_MC2_155      LDTSK---VTLPEKGTAAKESEKRAAARAEAE------------------
MAB_4293|M.abscessus_ATCC_1997      VGRTEDIRKALPAKGTAAAAAAERAATKTAEPEPVVAEEEAP----ATTK
TH_2670|M.thermoresistible__bu      ----------QADSGTAETET-----------------------------
                                               . .***                                 

Mflv_0278|M.gilvum_PYR-GCK          AEEAAPAEAKAGTATETKPVTGLGVAGGAKRPGAKK-TAAAPAEDKPAAA
Mvan_0619|M.vanbaalenii_PYR-1       AEPAEAAKSTAAADTESKPVTGLGLAGGAKRPGAKKPAAAEPAEDKP--A
Mb0345c|M.bovis_AF2122/97           AAPVTPVEAPAEAP------------------------------------
Rv0338c|M.tuberculosis_H37Rv        AAPVTPVEAPAEAP------------------------------------
MMAR_0611|M.marinum_M               AAPAAPAPAPAEAPAK---------------------AAEAPAAATAASP
MUL_0574|M.ulcerans_Agy99           AAPAAPAPAPAEAPAK---------------------AAEASAAATAASP
MAV_4817|M.avium_104                ATVEAPAKETTKEPAE---------------------AAP-KAEAAPAAP
MLBr_02501|M.leprae_Br4923          TESEAPAPE-----------------------------------------
MSMEG_0690|M.smegmatis_MC2_155      AKAEAAAPPVEEAAPE---------------------AEAPAAPAAGGAE
MAB_4293|M.abscessus_ATCC_1997      AEAAAPAAEAKPVSGLGMATGAKRPGAKKTAAENSTAEASTATPTAEAAP
TH_2670|M.thermoresistible__bu      -----PKPE-----------------------------------------
                                         .                                            

Mflv_0278|M.gilvum_PYR-GCK          AAPAKGLGIAGGAKRPGAKKAAPAAEAAPAADAPAKAEPEVKGLGIAGGA
Mvan_0619|M.vanbaalenii_PYR-1       PAPAKGLGIAGGAKRPGAKKAAPAAGTTP---------------------
Mb0345c|M.bovis_AF2122/97           --------------------QAPAPAAP----------------------
Rv0338c|M.tuberculosis_H37Rv        --------------------QAPAPAAP----------------------
MMAR_0611|M.marinum_M               AAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKK
MUL_0574|M.ulcerans_Agy99           AAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKK
MAV_4817|M.avium_104                AAPVKGLGIAGGAKRPGAKKSAPAAEAKTEAPAEAKTEAP----------
MLBr_02501|M.leprae_Br4923          -------------------KSTQAAAS-----------------------
MSMEG_0690|M.smegmatis_MC2_155      AKPVTGLGMAGAAKRPGAKKAAPAAEASAAPAAAPAPAKG-----LGLAG
MAB_4293|M.abscessus_ATCC_1997      AAPVKGLGMAAGAKRPGAKKATAETSAATPPAASASPPAS----------
TH_2670|M.thermoresistible__bu      --------------------------------------------------
                                                                                      

Mflv_0278|M.gilvum_PYR-GCK          KRPGAKKAAPAVEAAPAADAPAKAEPEAKGLGIAGGAKRPGAKKASGTVV
Mvan_0619|M.vanbaalenii_PYR-1       --------APAAESAAAAEP-AKAEPEVKGLGIAGGAKRPGAKKQAAPAA
Mb0345c|M.bovis_AF2122/97           ------------------------AAPVKGLGMAAGAKRPGAKKAAP---
Rv0338c|M.tuberculosis_H37Rv        ------------------------AAPVKGLGMAAGAKRPGAKKAAP---
MMAR_0611|M.marinum_M               PGAKKAAAPTGETKPAEAAAPAAPAAPVKGLGMASGAKRPGAKKAAPPAA
MUL_0574|M.ulcerans_Agy99           PGAKKAAAPTGETKPAEAAAP---AAPVKGLGMASGAKRPGAKKAAPPAA
MAV_4817|M.avium_104                ------------------------AAPAKGLGIAAGAKRPGAKKSAPAAQ
MLBr_02501|M.leprae_Br4923          ------------------------AAPAKGIRLAAGAKQPDAKKPVSQTT
MSMEG_0690|M.smegmatis_MC2_155      GAKRPGAKKAAAPAAEAPAAPASDAPPVKGLGLAGGAKRPGAKKTAAAAP
MAB_4293|M.abscessus_ATCC_1997      ---------------QAPAAAAAPAPPVKGLGMAAGAKRPGAKKTAPAAP
TH_2670|M.thermoresistible__bu      -------------------------PEVKGLGIAAGARRPGARKATSKAD
                                                             . .**: :*.**::*.*:*      

Mflv_0278|M.gilvum_PYR-GCK          QPPNVDPDKAEAGTESAGTADSDRGLDDAPKPEPEVKGLGIAAGARRPGA
Mvan_0619|M.vanbaalenii_PYR-1       --PAAAAPAATPAPEAP--AQPEAAAAAPAKPEPEVKGLGIAAGARRPGA
Mb0345c|M.bovis_AF2122/97           ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA
Rv0338c|M.tuberculosis_H37Rv        ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA
MMAR_0611|M.marinum_M               AAPEAAATASAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA
MUL_0574|M.ulcerans_Agy99           AAPEAAATAPAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA
MAV_4817|M.avium_104                APKTEAPKTEAPKTEAKTEAAGEAKTEAPAAPAAPVKGLGIAAGAKRPGA
MLBr_02501|M.leprae_Br4923          S----------------------AKATEAPAATVPVKGLGIAGGAKRPGA
MSMEG_0690|M.smegmatis_MC2_155      AEKPAATEAP-------------EASATPAAPAAPVKGLGLAAGAKRPGA
MAB_4293|M.abscessus_ATCC_1997      AAPAPEAAAVPSESE------APTATETSAVAEPPVKGLGIAAGARRPGA
TH_2670|M.thermoresistible__bu      TARADTAKADTADT-------AAAXTQAPAQPEPEVKGLAIAPGARRPGA
                                                                .. .   ****.:* **:****

Mflv_0278|M.gilvum_PYR-GCK          KKKAPAAAPDS----------------APAAAPES---------------
Mvan_0619|M.vanbaalenii_PYR-1       KKAPAAPAAESTSAPAESAPAPAESAPAPAATPEP---------------
Mb0345c|M.bovis_AF2122/97           KKTPPPAPG-LAEPAAQ---------PQPEAKPQP---------------
Rv0338c|M.tuberculosis_H37Rv        KKTPPPAPG-LAEPAAQ---------PQPEAKPQP---------------
MMAR_0611|M.marinum_M               KKAPARAEAPAAAAPAQ---------PEPEATPEP---------------
MUL_0574|M.ulcerans_Agy99           KKAPARAEAPSAAAPAQ---------PEPEATPEP---------------
MAV_4817|M.avium_104                KKAAPKAEAPKAEAEAAKAEAPKPEAPKAEAESKP---------------
MLBr_02501|M.leprae_Br4923          KKSPD-----QAETPAP---------TESKSEAKP---------------
MSMEG_0690|M.smegmatis_MC2_155      KKTAAAPAEKPAAAETEAPAPAETAAPAEPAKPEPPVVGLGIAAGARRPG
MAB_4293|M.abscessus_ATCC_1997      KKAAPATESAPEP-------------AQPATAPEP---------------
TH_2670|M.thermoresistible__bu      KKAPATPAPAPAEPAAP---------KQPEAS------------------
                                    ** .                          :                   

Mflv_0278|M.gilvum_PYR-GCK          ------------APAAPSSNGSDSS-----KGDDRVVGDEAPVKGLGIAK
Mvan_0619|M.vanbaalenii_PYR-1       ------------EPAPEAPSSGASD-----NGDTRVVGDEPPVKGLGIAK
Mb0345c|M.bovis_AF2122/97           ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR
Rv0338c|M.tuberculosis_H37Rv        ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR
MMAR_0611|M.marinum_M               ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR
MUL_0574|M.ulcerans_Agy99           ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR
MAV_4817|M.avium_104                ------------EPAKPSNGEGGS-----------SKPSQPPVKGLGIAR
MLBr_02501|M.leprae_Br4923          ------------EPSDHADG----N----------PAPPTAPVKRLGITR
MSMEG_0690|M.smegmatis_MC2_155      AKKAAAKPAAAPAPAAEKPAEQAAEPEKPAEKPAEPEKPEPPVVGLGIKP
MAB_4293|M.abscessus_ATCC_1997      -----------TEPATSAPKDEAPET---------SSTPEPPVKGLGIAP
TH_2670|M.thermoresistible__bu      ------------DTAGQAEQAGSAE-----------EKPQPPVKGLGIAK
                                                 .:                         .**  **:  

Mflv_0278|M.gilvum_PYR-GCK          GARRPGKR-
Mvan_0619|M.vanbaalenii_PYR-1       GARRPGKR-
Mb0345c|M.bovis_AF2122/97           GARPPGKR-
Rv0338c|M.tuberculosis_H37Rv        GARPPGKR-
MMAR_0611|M.marinum_M               GARPPGKR-
MUL_0574|M.ulcerans_Agy99           GARPPGKR-
MAV_4817|M.avium_104                GARPPGKR-
MLBr_02501|M.leprae_Br4923          SARPPGKH-
MSMEG_0690|M.smegmatis_MC2_155      GAKRPGKR-
MAB_4293|M.abscessus_ATCC_1997      GARRPGRRN
TH_2670|M.thermoresistible__bu      GARPPGKKR
                                    .*: **::