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VTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQPANGRTDELGTRIWTQITEVFGQRRLLQWSLP GLTHLFTMWGFFILLTVYIEAYGVLFQPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKE YGRKSRFYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAIAAVLYPLGQGANQI IETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVTFKRLPDGLGPLMPMESDGEPINFEDPSEDAVFGR GKIEDFTWKAMLDFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEKTAEKLEGLNL ETTKDKSRHVPESGFGRVPGHGPEQATRPLVGTAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIID MRRYQVMMESEFPSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYEYLFWVGCA GAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRSGNEFLFQQLAAQAVEILDGLFEGVNSVD RKIVVTCPHCFNTIGKEYRQLGGNYTVLHHTQLLNWLVHDKKLVPVTPVSQDITYHDPCYLGRHNKVYEA PRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERVDEALATNATTIATACPFCRVMVT DGVNDRQEEAGRSGVEVLDVAQVLLGSLDYDKAKLPAKGTAAAEITKTAGLSPAKPTESEAPAPEKSTQA AASAAPAKGIRLAAGAKQPDAKKPVSQTTSAKATEAPAATVPVKGLGIAGGAKRPGAKKSPDQAETPAPT ESKSEAKPEPSDHADGNPAPPTAPVKRLGITRSARPPGKH
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. leprae Br4923 | MLBr_02501 | - | - | 100% (880) | putative iron-sulphur-binding reductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0345c | - | 0.0 | 78.39% (893) | putative iron-sulfur-binding reductase |
M. gilvum PYR-GCK | Mflv_0278 | - | 0.0 | 66.48% (910) | hypothetical protein Mflv_0278 |
M. tuberculosis H37Rv | Rv0338c | - | 0.0 | 78.16% (893) | iron-sulfur-binding reductase |
M. abscessus ATCC 19977 | MAB_4293 | - | 0.0 | 51.33% (904) | putative Fe-S oxidoreductase |
M. marinum M | MMAR_0611 | - | 0.0 | 70.89% (986) | iron-sulphur-binding reductase |
M. avium 104 | MAV_4817 | - | 0.0 | 74.89% (908) | ferredoxin, 4Fe-4S |
M. smegmatis MC2 155 | MSMEG_0690 | - | 0.0 | 67.34% (940) | iron-sulfur cluster-binding protein |
M. thermoresistible (build 8) | TH_2670 | - | 1e-19 | 39.87% (158) | PUTATIVE - |
M. ulcerans Agy99 | MUL_0574 | - | 0.0 | 73.81% (924) | iron-sulphur-binding reductase |
M. vanbaalenii PYR-1 | Mvan_0619 | - | 0.0 | 67.32% (912) | hypothetical protein Mvan_0619 |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_0278|M.gilvum_PYR-GCK -METQMLIRIIAGVLMLAVVGVFAAKRVLWLTKLIRSGQPLSEGNNRKDH Mvan_0619|M.vanbaalenii_PYR-1 -MDTQMLIRIVVGVLMIAVVGVFAVKRVLWLTTLIRSGQPMSEGNNRKDH Mb0345c|M.bovis_AF2122/97 -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN Rv0338c|M.tuberculosis_H37Rv -MTTQTLIRLILGMSMTAVVGVFALRRVWWLYKLVMSGQ---PASGRTDN MMAR_0611|M.marinum_M -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD MUL_0574|M.ulcerans_Agy99 -MTTQMLIRLTVGMGMTAVVVVLALRRVWWLYKLIMSGQ---PASGRTDD MAV_4817|M.avium_104 -MTTQMLIRLVVGMGMTLIVAALAARRVLWLFKLITSGK---PAPGHTDD MLBr_02501|M.leprae_Br4923 -MTTQMLIRMVLGLSMTAVVLLFAARRVLWLYKLTMSGQ---PANGRTDE MSMEG_0690|M.smegmatis_MC2_155 MAHTLEVSRLIIGLLMTAIVLVFAAKRVLWLTKLIRSGQKTLDENGRKND MAB_4293|M.abscessus_ATCC_1997 -MSTATITLGIIGVIFSLVAWGSFFGGVVKMVRVILSGQ---PDRTRFRP TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK LQKRITTQFEEVFGQTRLLRWSIPGIAHFFTMWGFFVLATVYLEAFGLLV Mvan_0619|M.vanbaalenii_PYR-1 LKQRITTQFEEVFGQTRLLRWSVPGIAHFFTMWGFFVLATVYIEAFGQLV Mb0345c|M.bovis_AF2122/97 LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF Rv0338c|M.tuberculosis_H37Rv LGTRIWTQISEVLGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF MMAR_0611|M.marinum_M IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF MUL_0574|M.ulcerans_Agy99 IGARIWTQIAEVFGQRRLLRWSIPGIAHFFTMWGFFILLTVYIEAYGFLF MAV_4817|M.avium_104 PGKRVWAEVSEVFGQRRLLKWSIPGLAHFFTMWGFFILLTVYIEAYGLLF MLBr_02501|M.leprae_Br4923 LGTRIWTQITEVFGQRRLLQWSLPGLTHLFTMWGFFILLTVYIEAYGVLF MSMEG_0690|M.smegmatis_MC2_155 LQKRITTQITEVFGQTRLLRWSVPGIAHFFTMWGFFVLASVYLEAYGVLF MAB_4293|M.abscessus_ATCC_1997 FLPRLKQLIVEVVAHTRMNKFRTVGWAHWLVMVGFLGGFPLYFESYGQTF TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK DHDFHIPLIGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR Mvan_0619|M.vanbaalenii_PYR-1 DHDFHIPLVGRWDALGFLQDFFAVAVLLGIITFAIIRIVREPKKHGRDSR Mb0345c|M.bovis_AF2122/97 EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR Rv0338c|M.tuberculosis_H37Rv EERFHIPVIGRWDALGFLQDFFATAVFLGITTFAIIRILRNPREIGRSSR MMAR_0611|M.marinum_M VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR MUL_0574|M.ulcerans_Agy99 VENFSIPVIGHWDALGFLQDFFATAVFLGIATFAIIRIKRNPREIGRASR MAV_4817|M.avium_104 QDNFHIPIIGRWDALGFLQDFFATAVFLGIATFAVIRSMRSPREIGRSSR MLBr_02501|M.leprae_Br4923 QPNFHLPIIGRWNAIGFLQDFFALAVLTSTVTFAIIRMRNEPKEYGRKSR MSMEG_0690|M.smegmatis_MC2_155 DPEFHIPFIGRWPVLGFLQDFFAVAVLLGIIVFAIIRVVREPKKIGRDSR MAB_4293|M.abscessus_ATCC_1997 NPEFHWPIIGDTFLWHLWDELLGIGTVIGIVTLIIIRQLNHPRKPERLSR TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK FYGSHTGGAWLILFMIFNVIWTYALVRGAAAV--VGNLPYGNGAFFSQFM Mvan_0619|M.vanbaalenii_PYR-1 FYGSHTGGAWLILFMIFNVIWTYALVRGAGAN--TGALPYGNGAFFSQFM Mb0345c|M.bovis_AF2122/97 FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF Rv0338c|M.tuberculosis_H37Rv FYGSHNGGAWLVLLMIFNVIWTYVLVRGSAVN--NGTLPYGNGAFLSQLF MMAR_0611|M.marinum_M FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF MUL_0574|M.ulcerans_Agy99 FYGSHNSGAWLVLFMIFNVIWTYVLVRGSAVN--NETLPYGKGAFLSQLF MAV_4817|M.avium_104 FYGSHTGGAWLVLFMIFNVIWTYVLVRGSAVN--NGTLPYGKGAFLSQLF MLBr_02501|M.leprae_Br4923 FYGSHTGGAWLILFMIFNVIWTYAVFRGASVDALGEAFPYNSGAFFSHAI MSMEG_0690|M.smegmatis_MC2_155 FYGSHTGGAWEILFMIFLVIATYALFRGAAVNTLGERFPYQSGAFFSDFM MAB_4293|M.abscessus_ATCC_1997 FGGSNFFAAYTIEMIVLVEGLGMVLVKSGKIATFHNSHPSSD--FFTMNV TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK GWIMRPLGHTANEWIETIALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT Mvan_0619|M.vanbaalenii_PYR-1 GWIMHPLGEPANEWIETLALLAHIAIMLVFLLIVLHSKHLHIGLAPINVT Mb0345c|M.bovis_AF2122/97 GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT Rv0338c|M.tuberculosis_H37Rv GAILRPLGQPANEIIETTALLLHIGVMLAFLILVLHSKHLHIFLAPINVT MMAR_0611|M.marinum_M GAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT MUL_0574|M.ulcerans_Agy99 AAILRPLGQPANEIIETTALLAHIAVMLAFLIIVLHSKHLHIFLAPINVT MAV_4817|M.avium_104 GAILRPLGQPANEYIETAALLAHIAVMLAFLIIVLHSKHMHIFTAPINVI MLBr_02501|M.leprae_Br4923 AAVLYPLGQGANQIIETVALLLHIGVMLAFLLIVLHSKHLHIFLAPINVT MSMEG_0690|M.smegmatis_MC2_155 AWILRPLGATANMWIETVALMGHIGVMLVFLLIVLHSKHLHIGLAPINVT MAB_4293|M.abscessus_ATCC_1997 AQLLPESPIMVSVFAFIKMMSGGLFLLLVGRKLVWG-VAWHRFAAFFNIY TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK FKRLPNG---LGPLLPVESKGELVDFEDP-AEDAVLGRGKIEDFTWKGYL Mvan_0619|M.vanbaalenii_PYR-1 FKRMPNA---LGPLLPVEYKGELVDFEDP-AEDAVLGRGKIEDFTWKAYL Mb0345c|M.bovis_AF2122/97 FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML Rv0338c|M.tuberculosis_H37Rv FKRLPDG---LGPLLPLEADGKPIDFENP-SEDAVFGRGKIEDFTWKGML MMAR_0611|M.marinum_M FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML MUL_0574|M.ulcerans_Agy99 FKRLPDG---LGPLLPVEADGKPVDFENP-PDDAIFGRGKIEDFTWKGML MAV_4817|M.avium_104 FKRLPNG---LGPLLPIEYDGKPIDFENP-PDDAVFGRGKVEDFSWKAML MLBr_02501|M.leprae_Br4923 FKRLPDG---LGPLMPMESDGEPINFEDP-SEDAVFGRGKIEDFTWKAML MSMEG_0690|M.smegmatis_MC2_155 FKRLPNG---LGPLLPMESNGEYIDFEDP-AEDAVFGKGKIEDFTWKGYL MAB_4293|M.abscessus_ATCC_1997 FKRNADGSVALGAAKPMMSGGKVLEMESADPDVDAFGAGKVEDFSWKDLL TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYFLDGKES Mvan_0619|M.vanbaalenii_PYR-1 DMTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHLFAKAPYILGDKET Mb0345c|M.bovis_AF2122/97 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK-- Rv0338c|M.tuberculosis_H37Rv DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGQK-- MMAR_0611|M.marinum_M DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK-- MUL_0574|M.ulcerans_Agy99 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK-- MAV_4817|M.avium_104 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGDKQS MLBr_02501|M.leprae_Br4923 DFATCTECGRCQSQCPAWNTGKPLSPKLVIMDLRDHWMAKAPYILGEK-- MSMEG_0690|M.smegmatis_MC2_155 DFTTCTECGRCQSQCPAWNTGKPLSPKLVIMNLRDHMFAKAPYILGEKPS MAB_4293|M.abscessus_ATCC_1997 DVTTCTECGRCQSQCPAWNTGKPLSPKLLITSLRDHTYAKAPYLLAGE-- TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK PLENTPEGGLGEELRGEKHSEKHSHEHVPESGFERIPADSPLQATRPLVG Mvan_0619|M.vanbaalenii_PYR-1 PLENTPEGGLGEELRGEKQSEEHSHEHVPESGFERIMGSGPEQATRPLVG Mb0345c|M.bovis_AF2122/97 --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG Rv0338c|M.tuberculosis_H37Rv --DASAGG----EAGHQ------EHHHVPESGFGRVPGHGPEQATRPLVG MMAR_0611|M.marinum_M --TADPLEGLDLETAAE------EGHHVPESGFGRVPGDGPEQAARPLVG MUL_0574|M.ulcerans_Agy99 --TADLLEGLDLETAAG------EGHHVPESGFGRVPGDGPEQAARPLVG MAV_4817|M.avium_104 PLESTPEGGVGEELSGEK---HAEAHHVPESGFGRVMGSGPEQATRPLVG MLBr_02501|M.leprae_Br4923 --TAEKLEGLNLETTKD------KSRHVPESGFGRVPGHGPEQATRPLVG MSMEG_0690|M.smegmatis_MC2_155 PLESTPEGGLGEKARGEKHEQKHAHDHVPESGFERILGSGPEQALRPLVG MAB_4293|M.abscessus_ATCC_1997 -------------------------------DKSKLSEAEIAEGERQLVG TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK TLEEGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF Mvan_0619|M.vanbaalenii_PYR-1 TLEQGGVIDPDVLWSCTTCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF Mb0345c|M.bovis_AF2122/97 TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF Rv0338c|M.tuberculosis_H37Rv TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF MMAR_0611|M.marinum_M TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF MUL_0574|M.ulcerans_Agy99 TAEQGGVIDPDVLWSCVSCGACVEQCPVDIEHIDHIVDMRRYQVMMESEF MAV_4817|M.avium_104 TEEQGGVIDPDVLWSCVTCGACVEQCPVDIEHVDHIVDMRRYQVMMESEF MLBr_02501|M.leprae_Br4923 TAEQGGVIDPDVLWSCVTCGACVEQCPVDIEHIDHIIDMRRYQVMMESEF MSMEG_0690|M.smegmatis_MC2_155 TEEQGGVIDPDVLWSCTNCGACVEQCPVDIEHIDHIVDMRRYQVMVESEF MAB_4293|M.abscessus_ATCC_1997 G--EGAVIDHEVLWSCTTCGACVEQCPVDIEHVDHIIDMRRYQVLIESEF TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK PGELGVLFKNLETKGNPWGQNSKDRTNWIDEVDFDVPVFGKDVDSFEGYE Mvan_0619|M.vanbaalenii_PYR-1 PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGKDVESFDGFE Mb0345c|M.bovis_AF2122/97 PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE Rv0338c|M.tuberculosis_H37Rv PSELSVLFKNLETKGNPWGQNASDRTNWIDEVDFDVPVYGQDVDSFDGYE MMAR_0611|M.marinum_M PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE MUL_0574|M.ulcerans_Agy99 PSELSVLFKNLENKGNPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE MAV_4817|M.avium_104 PSELSVLFKNLETKANPWGQNASDRTNWIDEVDFDVPVYGEDVDSFDGYE MLBr_02501|M.leprae_Br4923 PSELSTLFKNLETKGNPWGQNAGDRTNWIDEVDFDVPVYGEDVDSFDGYE MSMEG_0690|M.smegmatis_MC2_155 PGELGVLFKNLETKGNPWGQNAKDRTNWIDEVDFDVPVYGEDVDSFDGFE MAB_4293|M.abscessus_ATCC_1997 PGELAGLFKNLENKGNPWGQNAKDRLNWIEEVDFDVPVFGQDVDSFADFE TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK YLFWVGCAGAYEDRAKKTTKAVAELLSAAGVKYLVLGEGETCNGDSARRS Mvan_0619|M.vanbaalenii_PYR-1 YLFWVGCAGAYEDRAKKTTKAVAELLAAAGVKYLVLGEGETCNGDSARRS Mb0345c|M.bovis_AF2122/97 YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS Rv0338c|M.tuberculosis_H37Rv YLFWVGCAGAYDDKAKKTTKAVAELLAVARVKYLVLGAGETCNGDSARRS MMAR_0611|M.marinum_M YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS MUL_0574|M.ulcerans_Agy99 YLFWVGCAGAYDDKAKKTTKAVAELLATAGVKFMVLGAGETCNGDSARRS MAV_4817|M.avium_104 YLFWVGCAGAYDDKAKKTTKAVAELLAVAGVKYLVLGAGETCNGDSARRS MLBr_02501|M.leprae_Br4923 YLFWVGCAGAYDDKAKKTTKAVAELLAIAGVKYLVLGTGETCNGDSAHRS MSMEG_0690|M.smegmatis_MC2_155 YLFWVGCAGAYEDRAKKTTKAVAELLATAGVKFLVLGTGETCTGDSARRS MAB_4293|M.abscessus_ATCC_1997 YLFWVGCAGAYEDRAKKTTKAVAELLALAGTKFLVLGADETCTGDSARRA TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK GNEFLFQQLAAQNVETLNDLFSGIERVDRKVVVTCPHCFNTLGREYPQVG Mvan_0619|M.vanbaalenii_PYR-1 GNEFLFQQLAAQNVETLGELFEGVERVDRKVVVTCPHCFNTLGREYPQLG Mb0345c|M.bovis_AF2122/97 GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG Rv0338c|M.tuberculosis_H37Rv GNEFLFQQLAQQAVETLDGLFEGVETVDRKIVVTCPHCFNTIGKEYRQLG MMAR_0611|M.marinum_M GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG MUL_0574|M.ulcerans_Agy99 GNEFLFQQLAQQAIETLDGVFEGVETVDRKVVVTCPHCFNTLGKEYRQLG MAV_4817|M.avium_104 GNEFLFQQLAAQAVETLDGVFEGVETVDRKIVVTCPHCFNTLGREYRQLG MLBr_02501|M.leprae_Br4923 GNEFLFQQLAAQAVEILDGLFEGVNSVDRKIVVTCPHCFNTIGKEYRQLG MSMEG_0690|M.smegmatis_MC2_155 GNEFLFQQLAAQNVETINELFEGVETVDRKIVVTCPHCFNTIGREYPQLG MAB_4293|M.abscessus_ATCC_1997 GNEFLFQQLAMQNIELLNSVFEGVEQKQRKIVVTCAHCFNALGNEYPQVG TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK GNYTVLHHTQLLNRLVRDKKLVPVKSTDGSPNGQDITYHDPCYLGRHNKE Mvan_0619|M.vanbaalenii_PYR-1 GNYTVLHHTQLLNRLVRDKKLVPVKSTD---NGQDITYHDPCYLGRHNKE Mb0345c|M.bovis_AF2122/97 ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKV Rv0338c|M.tuberculosis_H37Rv ANYTVLHHTQLLNRLVRDKRLVPVTPVS-----QDITYHDPCYLGRHNKA MMAR_0611|M.marinum_M SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV MUL_0574|M.ulcerans_Agy99 SNYSVLHHTQLLNRLIRDKKLVPVTPVS-----QDVTYHDPCYLGRHNKV MAV_4817|M.avium_104 ANYTVLHHTQLLNRLIRDNKLVPVTPVS-----QDITYHDPCYLGRHNKV MLBr_02501|M.leprae_Br4923 GNYTVLHHTQLLNWLVHDKKLVPVTPVS-----QDITYHDPCYLGRHNKV MSMEG_0690|M.smegmatis_MC2_155 ANYSVVHHTQLLNRLVRDKKLVPVKSVSEQ-NGQPVTYHDPCFLGRHNKV MAB_4293|M.abscessus_ATCC_1997 GDYQVVHHTQLLNRLVRDKKLVPVAPVS-----QDVTYHDPCYLGRHNKV TH_2670|M.thermoresistible__bu -----------MFHVKHGRPQSPSIPDG---------------------- : : :.. * . . Mflv_0278|M.gilvum_PYR-GCK YSAPRELIGASGAKLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT Mvan_0619|M.vanbaalenii_PYR-1 YSAPRELIGASGATLTEMPRHADRGLCCGAGGARMWMEEHIGKRVNTERT Mb0345c|M.bovis_AF2122/97 YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV Rv0338c|M.tuberculosis_H37Rv YEAPRELIGAAGASLTEMPRHADRSFCCGAGGARMWMEEHIGKRINHERV MMAR_0611|M.marinum_M YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV MUL_0574|M.ulcerans_Agy99 YEAPRELIGAAGANLAEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV MAV_4817|M.avium_104 YEAPRELIGAAGANLTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV MLBr_02501|M.leprae_Br4923 YEAPRELVRAAGANFTEMPRHAERSFCCGAGGARMWMEEHIGKRINHERV MSMEG_0690|M.smegmatis_MC2_155 YEAPRELVEASGVTLKEMPRHADRGLCCGAGGARMWMEEHIGKRVNVERT MAB_4293|M.abscessus_ATCC_1997 YTAPRELIGASGAAITEMPRHGERSMCCGAGGARMWMEEQLGKRINIDRV TH_2670|M.thermoresistible__bu --IPPXXXXADGEKTGGAP--AAKGLSIAAG------------------- * * * * . :.:. .** Mflv_0278|M.gilvum_PYR-GCK EEAIDTGASAIATGCPFCRVMMTDGVDDVSATRDIEKVEVLDVAQLLLGS Mvan_0619|M.vanbaalenii_PYR-1 EEAIDTGASAIATGCPFCRVMMTDGVDDVSAAREIEKVEVLDVAQLLLGS Mb0345c|M.bovis_AF2122/97 DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS Rv0338c|M.tuberculosis_H37Rv DEALATDATAIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS MMAR_0611|M.marinum_M DEALATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS MUL_0574|M.ulcerans_Agy99 DEAVATNASTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS MAV_4817|M.avium_104 DEALATGAATVATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQILLGS MLBr_02501|M.leprae_Br4923 DEALATNATTIATACPFCRVMVTDGVNDRQEEAGRSGVEVLDVAQVLLGS MSMEG_0690|M.smegmatis_MC2_155 EEAMDT-ASTIATGCPFCRVMITDGVDDVAASRNVEKAEVLDVAQLLLNS MAB_4293|M.abscessus_ATCC_1997 DEALSTPASKIATGCPFCRVMLTDGVTARDD---SAAVEVVDVAQLLLES TH_2670|M.thermoresistible__bu --AKRPGAKKTAPAG----------------------------------- * . * *.. Mflv_0278|M.gilvum_PYR-GCK LDKST---FTLPEKGTAAKESEERAARIAAEAPAEVEAEEPE-----AAP Mvan_0619|M.vanbaalenii_PYR-1 LDQSS---FTLPEKGTAAKEAEERAARVAAQAPAKAEESAIETEAEAKTA Mb0345c|M.bovis_AF2122/97 LDHDK---AQLPAKGTAAKQAQERAPKAAPKA------------------ Rv0338c|M.tuberculosis_H37Rv LDHDK---AQLPAKGTAAKQAQERAPKAAPKA------------------ MMAR_0611|M.marinum_M LDREK---ATLPEKGTAAKEAEKRA-KAAPKA------------------ MUL_0574|M.ulcerans_Agy99 LDREK---ATLPEKGTAAKEAEKRA-KTAPKA------------------ MAV_4817|M.avium_104 LEYDK---ATLPEKGTAAKEAEKRAAQAPKAT------------------ MLBr_02501|M.leprae_Br4923 LDYDK---AKLPAKGTAAAEITKTAGLSPAKP------------------ MSMEG_0690|M.smegmatis_MC2_155 LDTSK---VTLPEKGTAAKESEKRAAARAEAE------------------ MAB_4293|M.abscessus_ATCC_1997 VGRTEDIRKALPAKGTAAAAAAERAATKTAEPEPVVAEEEAP----ATTK TH_2670|M.thermoresistible__bu ----------QADSGTAETET----------------------------- . .*** Mflv_0278|M.gilvum_PYR-GCK AEEAAPAEAKAGTATETKPVTGLGVAGGAKRPGAKK-TAAAPAEDKPAAA Mvan_0619|M.vanbaalenii_PYR-1 AEPAEAAKSTAAADTESKPVTGLGLAGGAKRPGAKKPAAAEPAEDKP--A Mb0345c|M.bovis_AF2122/97 AAPVTPVEAPAEAP------------------------------------ Rv0338c|M.tuberculosis_H37Rv AAPVTPVEAPAEAP------------------------------------ MMAR_0611|M.marinum_M AAPAAPAPAPAEAPAK---------------------AAEAPAAATAASP MUL_0574|M.ulcerans_Agy99 AAPAAPAPAPAEAPAK---------------------AAEASAAATAASP MAV_4817|M.avium_104 ATVEAPAKETTKEPAE---------------------AAP-KAEAAPAAP MLBr_02501|M.leprae_Br4923 TESEAPAPE----------------------------------------- MSMEG_0690|M.smegmatis_MC2_155 AKAEAAAPPVEEAAPE---------------------AEAPAAPAAGGAE MAB_4293|M.abscessus_ATCC_1997 AEAAAPAAEAKPVSGLGMATGAKRPGAKKTAAENSTAEASTATPTAEAAP TH_2670|M.thermoresistible__bu -----PKPE----------------------------------------- . Mflv_0278|M.gilvum_PYR-GCK AAPAKGLGIAGGAKRPGAKKAAPAAEAAPAADAPAKAEPEVKGLGIAGGA Mvan_0619|M.vanbaalenii_PYR-1 PAPAKGLGIAGGAKRPGAKKAAPAAGTTP--------------------- Mb0345c|M.bovis_AF2122/97 --------------------QAPAPAAP---------------------- Rv0338c|M.tuberculosis_H37Rv --------------------QAPAPAAP---------------------- MMAR_0611|M.marinum_M AAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKK MUL_0574|M.ulcerans_Agy99 AAPAKGLGMAGGAKRPGAKKAAPAPAAETAAAEAPAAPAKGLGMAAGAKK MAV_4817|M.avium_104 AAPVKGLGIAGGAKRPGAKKSAPAAEAKTEAPAEAKTEAP---------- MLBr_02501|M.leprae_Br4923 -------------------KSTQAAAS----------------------- MSMEG_0690|M.smegmatis_MC2_155 AKPVTGLGMAGAAKRPGAKKAAPAAEASAAPAAAPAPAKG-----LGLAG MAB_4293|M.abscessus_ATCC_1997 AAPVKGLGMAAGAKRPGAKKATAETSAATPPAASASPPAS---------- TH_2670|M.thermoresistible__bu -------------------------------------------------- Mflv_0278|M.gilvum_PYR-GCK KRPGAKKAAPAVEAAPAADAPAKAEPEAKGLGIAGGAKRPGAKKASGTVV Mvan_0619|M.vanbaalenii_PYR-1 --------APAAESAAAAEP-AKAEPEVKGLGIAGGAKRPGAKKQAAPAA Mb0345c|M.bovis_AF2122/97 ------------------------AAPVKGLGMAAGAKRPGAKKAAP--- Rv0338c|M.tuberculosis_H37Rv ------------------------AAPVKGLGMAAGAKRPGAKKAAP--- MMAR_0611|M.marinum_M PGAKKAAAPTGETKPAEAAAPAAPAAPVKGLGMASGAKRPGAKKAAPPAA MUL_0574|M.ulcerans_Agy99 PGAKKAAAPTGETKPAEAAAP---AAPVKGLGMASGAKRPGAKKAAPPAA MAV_4817|M.avium_104 ------------------------AAPAKGLGIAAGAKRPGAKKSAPAAQ MLBr_02501|M.leprae_Br4923 ------------------------AAPAKGIRLAAGAKQPDAKKPVSQTT MSMEG_0690|M.smegmatis_MC2_155 GAKRPGAKKAAAPAAEAPAAPASDAPPVKGLGLAGGAKRPGAKKTAAAAP MAB_4293|M.abscessus_ATCC_1997 ---------------QAPAAAAAPAPPVKGLGMAAGAKRPGAKKTAPAAP TH_2670|M.thermoresistible__bu -------------------------PEVKGLGIAAGARRPGARKATSKAD . .**: :*.**::*.*:* Mflv_0278|M.gilvum_PYR-GCK QPPNVDPDKAEAGTESAGTADSDRGLDDAPKPEPEVKGLGIAAGARRPGA Mvan_0619|M.vanbaalenii_PYR-1 --PAAAAPAATPAPEAP--AQPEAAAAAPAKPEPEVKGLGIAAGARRPGA Mb0345c|M.bovis_AF2122/97 ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA Rv0338c|M.tuberculosis_H37Rv ------------------------TPAAPAAPAAPVKGLGIAAGAKRPGA MMAR_0611|M.marinum_M AAPEAAATASAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA MUL_0574|M.ulcerans_Agy99 AAPEAAATAPAPE--------AAAAPAEPAAPAAPVKGLGIATGAKRPGA MAV_4817|M.avium_104 APKTEAPKTEAPKTEAKTEAAGEAKTEAPAAPAAPVKGLGIAAGAKRPGA MLBr_02501|M.leprae_Br4923 S----------------------AKATEAPAATVPVKGLGIAGGAKRPGA MSMEG_0690|M.smegmatis_MC2_155 AEKPAATEAP-------------EASATPAAPAAPVKGLGLAAGAKRPGA MAB_4293|M.abscessus_ATCC_1997 AAPAPEAAAVPSESE------APTATETSAVAEPPVKGLGIAAGARRPGA TH_2670|M.thermoresistible__bu TARADTAKADTADT-------AAAXTQAPAQPEPEVKGLAIAPGARRPGA .. . ****.:* **:**** Mflv_0278|M.gilvum_PYR-GCK KKKAPAAAPDS----------------APAAAPES--------------- Mvan_0619|M.vanbaalenii_PYR-1 KKAPAAPAAESTSAPAESAPAPAESAPAPAATPEP--------------- Mb0345c|M.bovis_AF2122/97 KKTPPPAPG-LAEPAAQ---------PQPEAKPQP--------------- Rv0338c|M.tuberculosis_H37Rv KKTPPPAPG-LAEPAAQ---------PQPEAKPQP--------------- MMAR_0611|M.marinum_M KKAPARAEAPAAAAPAQ---------PEPEATPEP--------------- MUL_0574|M.ulcerans_Agy99 KKAPARAEAPSAAAPAQ---------PEPEATPEP--------------- MAV_4817|M.avium_104 KKAAPKAEAPKAEAEAAKAEAPKPEAPKAEAESKP--------------- MLBr_02501|M.leprae_Br4923 KKSPD-----QAETPAP---------TESKSEAKP--------------- MSMEG_0690|M.smegmatis_MC2_155 KKTAAAPAEKPAAAETEAPAPAETAAPAEPAKPEPPVVGLGIAAGARRPG MAB_4293|M.abscessus_ATCC_1997 KKAAPATESAPEP-------------AQPATAPEP--------------- TH_2670|M.thermoresistible__bu KKAPATPAPAPAEPAAP---------KQPEAS------------------ ** . : Mflv_0278|M.gilvum_PYR-GCK ------------APAAPSSNGSDSS-----KGDDRVVGDEAPVKGLGIAK Mvan_0619|M.vanbaalenii_PYR-1 ------------EPAPEAPSSGASD-----NGDTRVVGDEPPVKGLGIAK Mb0345c|M.bovis_AF2122/97 ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR Rv0338c|M.tuberculosis_H37Rv ------------EPAAPPKPQTDGD----------PAAPAAPVKGLGIAR MMAR_0611|M.marinum_M ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR MUL_0574|M.ulcerans_Agy99 ------------EPASKQDGEPTP-----------PAAPAAPVKGLGMAR MAV_4817|M.avium_104 ------------EPAKPSNGEGGS-----------SKPSQPPVKGLGIAR MLBr_02501|M.leprae_Br4923 ------------EPSDHADG----N----------PAPPTAPVKRLGITR MSMEG_0690|M.smegmatis_MC2_155 AKKAAAKPAAAPAPAAEKPAEQAAEPEKPAEKPAEPEKPEPPVVGLGIKP MAB_4293|M.abscessus_ATCC_1997 -----------TEPATSAPKDEAPET---------SSTPEPPVKGLGIAP TH_2670|M.thermoresistible__bu ------------DTAGQAEQAGSAE-----------EKPQPPVKGLGIAK .: .** **: Mflv_0278|M.gilvum_PYR-GCK GARRPGKR- Mvan_0619|M.vanbaalenii_PYR-1 GARRPGKR- Mb0345c|M.bovis_AF2122/97 GARPPGKR- Rv0338c|M.tuberculosis_H37Rv GARPPGKR- MMAR_0611|M.marinum_M GARPPGKR- MUL_0574|M.ulcerans_Agy99 GARPPGKR- MAV_4817|M.avium_104 GARPPGKR- MLBr_02501|M.leprae_Br4923 SARPPGKH- MSMEG_0690|M.smegmatis_MC2_155 GAKRPGKR- MAB_4293|M.abscessus_ATCC_1997 GARRPGRRN TH_2670|M.thermoresistible__bu GARPPGKKR .*: **::