For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
IVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSGGYTYPPGPPPPPYSYGGPFGGPSPRSSSG NRAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVPTPTAQPATTLPPAGASLSVSG VNVNRTIACNDSIVSVSGMSNTVVITGHCTSLTVSGMRNSVTVDSVDTIEAAGFNNEVTYHSGSPKISNA GGSNSVQQG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0314c | - | - | 100% (220) | POSSIBLE CONSERVED MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv0679c | - | 1e-11 | 29.91% (117) | putative threonine rich protein |
| M. tuberculosis H37Rv | Rv0680c | - | 5e-09 | 31.78% (107) | transmembrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0322c | - | 1e-126 | 99.55% (220) | hypothetical protein Mb0322c |
| M. gilvum PYR-GCK | Mflv_5128 | - | 7e-39 | 39.75% (239) | hypothetical protein Mflv_5128 |
| M. leprae Br4923 | MLBr_00431 | - | 2e-05 | 26.22% (164) | hypothetical protein MLBr_00431 |
| M. abscessus ATCC 19977 | MAB_1176c | - | 1e-33 | 37.27% (220) | hypothetical protein MAB_1176c |
| M. marinum M | MMAR_0565 | - | 9e-65 | 54.17% (240) | hypothetical protein MMAR_0565 |
| M. avium 104 | MAV_4846 | - | 4e-64 | 55.61% (223) | hypothetical protein MAV_4846 |
| M. smegmatis MC2 155 | MSMEG_5317 | - | 4e-36 | 37.75% (249) | hypothetical protein MSMEG_5317 |
| M. thermoresistible (build 8) | TH_1896 | - | 1e-10 | 30.10% (103) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_4742 | - | 1e-70 | 56.79% (243) | hypothetical protein MUL_4742 |
| M. vanbaalenii PYR-1 | Mvan_1215 | - | 1e-38 | 40.08% (237) | hypothetical protein Mvan_1215 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0314c|M.tuberculosis_H37Rv ----MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSG----
Mb0322c|M.bovis_AF2122/97 ----MIVVWEHLCMNPEDDPEARIRELERPLADVARASELGGSQSG----
MMAR_0565|M.marinum_M -------------MNPEDDPEARIRQLEQPLADAARASELGSSQPAGESA
MUL_4742|M.ulcerans_Agy99 -------MWEHLCMNPEDDPEARIRQLEQPLADAARASELGSSQPAGESA
MAV_4846|M.avium_104 -------------MAANDDPEERIRELERPLADSARASEQGSAPPTG---
MAB_1176c|M.abscessus_ATCC_199 -------------MEPDGDPEARIRELERPLSERAQRSELGA--------
MSMEG_5317|M.smegmatis_MC2_155 -------MCEHLRMDPQDDPEARIRDLERSLAERAKELGTGADEGHAPPA
Mflv_5128|M.gilvum_PYR-GCK -------MCQHLRMEPNGDPEARIRDLERPLADRARASELGTHPYGAPPV
Mvan_1215|M.vanbaalenii_PYR-1 -------MCKHLPMEPSGDPEARIRDLERPLADQAAANELGTHAY-----
TH_1896|M.thermoresistible__bu --------------------------------------------------
MLBr_00431|M.leprae_Br4923 MNNPRRSEWLGPSLAGSGPIEPQVHQYP-PLTDPAYAEQAPYAPAYGASL
Rv0314c|M.tuberculosis_H37Rv --------------GYTYPPGPPPPP---YSYGGPFGGPSPR---SSSGN
Mb0322c|M.bovis_AF2122/97 --------------GYTYPPGPPPPP---YSYGGPFGGPSPR---SSSGN
MMAR_0565|M.marinum_M YQNYQGYQGYQGYPGYQPPPGSVPPS---YGYQPAFPGATPR---SSSGN
MUL_4742|M.ulcerans_Agy99 YQNYQG------YPGYQPPPGSVPPSPPPYGYQPAFPGATPR---SSSGN
MAV_4846|M.avium_104 -------------PGYPPAPAP-------WSYGGPVPGPPGQ---RPSGN
MAB_1176c|M.abscessus_ATCC_199 -----PSQ-------SPYPLP-----------AYDTTQISR--SPVRTFR
MSMEG_5317|M.smegmatis_MC2_155 PPPPPPTQPWTQTFGTAYPPPPPGPPAPWPGYAEDFPAPPRQHVPVAHTG
Mflv_5128|M.gilvum_PYR-GCK PPYQDVALP--PMPPGVEHPAP--------VYGSPYYAPPQRVVHKRSN-
Mvan_1215|M.vanbaalenii_PYR-1 ---QDVAPPTTPVPPYPYPPYA--------QYGSPYYAPPQRVVDKRSHT
TH_1896|M.thermoresistible__bu --------------------------------------------------
MLBr_00431|M.leprae_Br4923 PPWTPKKPPQQLPRYWQQDQPPPTDIP---PEGLTLPPPHEP----KSPH
Rv0314c|M.tuberculosis_H37Rv RAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVP--
Mb0322c|M.bovis_AF2122/97 RAWWILAAVVVVGVLVLVGGIAAFSAQRLSQGNFVVLSPTPSVSRAVP--
MMAR_0565|M.marinum_M RAFWIIAAVFVVGILGAVAAVALFAVNRVSEP-FTTLSPGTTVISTPPGP
MUL_4742|M.ulcerans_Agy99 RAFWIIAAVFVVGILGAVAAVALFAVNRVSEP-FTTLSPGTTVISTPPGP
MAV_4846|M.avium_104 RVWWVVGTLIAVGVLALAGGIAAFAAHQLSGVKSIINSPPTISRTFGPPP
MAB_1176c|M.abscessus_ATCC_199 RRFLVFLAV----ITAGAAGLVFYAAEPTIRQGGPTVSGPSGTRPARSTV
MSMEG_5317|M.smegmatis_MC2_155 RILMILVAVAVFLITTGIAAFLMFTNTVTSSLQ-PVADNPAG-RPALP--
Mflv_5128|M.gilvum_PYR-GCK TALWLIPVVVVVVLAAGIIGIVAYFSSGTPDSYT--YTPPVSGGGGPLDA
Mvan_1215|M.vanbaalenii_PYR-1 TALWLIPLVVVGAIVAGAVAVVVFFNTGSPDSATPIPVPPISGGGGPLDP
TH_1896|M.thermoresistible__bu MGHDVIRTVIGAFAAAAALGLAG---CGSQDGDT--PGPSATAG------
MLBr_00431|M.leprae_Br4923 WFLWVVAGASVVLVVGLVMALIIANGAIKTQTAVPPLPAITESSSATPTP
:. ..
Rv0314c|M.tuberculosis_H37Rv --------TPTAQPATTL-PPAGASLSVSGVNVNRTIACNDS-IVSVSGM
Mb0322c|M.bovis_AF2122/97 --------TPTAQPATTL-PPAGASLSVSGVNVNRTIACNDS-IVSVSGM
MMAR_0565|M.marinum_M MSPGNKTQTPTAGPSTSAGPPAGSTISVVGVNQSQTITCNDN-IVNVSGM
MUL_4742|M.ulcerans_Agy99 MSPGNKTQTPTAGPSTSAGPPAGSTISVVGVNQSQTITCNDN-IVNVSGM
MAV_4846|M.avium_104 GISTTPAPSTSRRTPTSPAAPPGTELSVAGINENRTLACDDN-PVSVSGV
MAB_1176c|M.abscessus_ATCC_199 V-KIPRATPSSTAAPGPTFVPAGSTFSVAGTHKNVAISCDGC-SVSVSGV
MSMEG_5317|M.smegmatis_MC2_155 --YSPPSNPVFPAIETPSVAGPGEVINVAGASNDREVTCDGG-TVMVSGV
Mflv_5128|M.gilvum_PYR-GCK P-LPPQVQTRTDSTEQVITVDSGGFVSIGGVEKNQTIVCDEG-TVSISGV
Mvan_1215|M.vanbaalenii_PYR-1 ---PPSVQTRIESTEQIVTVESGGFVSLGGVETRQTVVCDDG-TVNISGV
TH_1896|M.thermoresistible__bu --------------EDGVRVEIANTINYGSFGTTTEIDCADGKSLNIGGS
MLBr_00431|M.leprae_Br4923 TTKTSPTPTAGPAPSTTGSGTLTQTIGPSAMLDVVYSITGQGRAISVTYM
.. . : :
Rv0314c|M.tuberculosis_H37Rv SNTVVITGHCTSLTVSGMRNSVTVDSVD--TIEAAGFNNEVTYHS---GS
Mb0322c|M.bovis_AF2122/97 SNTVVITGHCTSLTVSGMRNSVTADSVD--TIEAAGFNNEVTYHS---GS
MMAR_0565|M.marinum_M SNTVTITGHCASVSVSGLQNTVTVETAD--RITASGLNNKVTYQS---GS
MUL_4742|M.ulcerans_Agy99 SNTVTITGHCASVSVSGLQNTVTVETAD--RITASGLNNKVTYQS---GS
MAV_4846|M.avium_104 SNTVVITGHCTSLSVSGVQNTVTVEAVE--RIGASGFNNKVTYHS---GT
MAB_1176c|M.abscessus_ATCC_199 SHTVEILGNCDTLTVSGVENTVTVETAV--KIGVSGIDNQVTYRT---GE
MSMEG_5317|M.smegmatis_MC2_155 ENTITITGHCAAVTISGIRNVIEVDEAD--TIGVSGFENRVTYSS---GE
Mflv_5128|M.gilvum_PYR-GCK NNTIEVTGRCGSVTVSGVDNTVTVESAG--TISASGFHNRVTFLA---GD
Mvan_1215|M.vanbaalenii_PYR-1 NNTIEVQGACTMVTVSGVENTVTVESAD--TISASGFDNRVTYRT---GT
TH_1896|M.thermoresistible__bu NNTLTVLGTCANVNVGGTDNRITVERVDN-EISVTGFNNTLTYRD---GD
MLBr_00431|M.leprae_Br4923 DTGDVIQTEFNVVLPWSKQVSLSKSAVHPASVTIVNIGHDVTCSVTVAGV
. : : . : . . : .: : :* *
Rv0314c|M.tuberculosis_H37Rv PKISNAGGSNSVQQG--
Mb0322c|M.bovis_AF2122/97 PKISNAGGSNSVQQG--
MMAR_0565|M.marinum_M PKISKSGSGNVIEQG--
MUL_4742|M.ulcerans_Agy99 PKISKSGSGNVIEQG--
MAV_4846|M.avium_104 PSISNSGGSNVVGRG--
MAB_1176c|M.abscessus_ATCC_199 PQVAKSGNNNTVEQS--
MSMEG_5317|M.smegmatis_MC2_155 PEITKSGMDNTVERRAP
Mflv_5128|M.gilvum_PYR-GCK PQTSTSGSGNVIERQ--
Mvan_1215|M.vanbaalenii_PYR-1 PEISKSGRGNVVEPG--
TH_1896|M.thermoresistible__bu PTVSDTGRGNNIGRG--
MLBr_00431|M.leprae_Br4923 QIRQHTGVGLTICDAPR
:* . :