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VTGPAFSPQERRAVYRVISERRDMRRFVAGAVVDEQVLARLLAAAHAAPSVGLMQPWRFIRITDAALRRR IHALVEQERPRTAAALGERAQEFLALKVEGILECAELLVVALGDDRDKHVFGRRTLPQMDLASVSCAIQN LWLAARAEGLGMGWVSLFEPRPLAELLGLPDGAEPVAILCLGPVPEFPDRPALELDGWATPRPLAEFVCE NRWAQPQLP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4857 | bluB | - | 100% (219) | cob(II)yrinic acid a,c-diamide reductase |
| M. avium 104 | MAV_0933 | - | 1e-08 | 29.65% (226) | nitroreductase family protein |
| M. avium 104 | MAV_4225 | - | 5e-06 | 26.01% (173) | F420-0--gamma-glutamyl ligase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0314 | - | 1e-94 | 81.04% (211) | putative oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0353 | - | 1e-45 | 48.33% (209) | cob(II)yrinic acid a,c-diamide reductase |
| M. tuberculosis H37Rv | Rv0306 | - | 1e-94 | 81.04% (211) | putative oxidoreductase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_3351c | - | 2e-40 | 46.04% (202) | putative nitroreductase |
| M. marinum M | MMAR_0555 | - | 3e-98 | 81.60% (212) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_6053 | bluB | 8e-96 | 79.15% (211) | cob(II)yrinic acid a,c-diamide reductase |
| M. thermoresistible (build 8) | TH_1748 | - | 9e-83 | 75.79% (190) | PUTATIVE OXIDOREDUCTASE |
| M. ulcerans Agy99 | MUL_1218 | - | 1e-98 | 80.56% (216) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_0381 | - | 7e-41 | 48.45% (194) | cob(II)yrinic acid a,c-diamide reductase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0555|M.marinum_M MADYAFTAQERQAVYRVITERRDMRRFVPGAMVPEDVLTRLLHAAHAAPN
MUL_1218|M.ulcerans_Agy99 MTDYAFTAQERQAVYRVLTERRDMRHFVPGAVVPEDVLTRLLHAAHAAPN
Mb0314|M.bovis_AF2122/97 ----MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPS
Rv0306|M.tuberculosis_H37Rv ----MFSAPERRAVYRVIAERRDMRRFVPGGVVSEDVLARLLHAAHAAPS
MAV_4857|M.avium_104 MTGPAFSPQERRAVYRVISERRDMRRFVAGAVVDEQVLARLLAAAHAAPS
MSMEG_6053|M.smegmatis_MC2_155 MPRHAFSPSERQAVYRAITERRDMRQFVPGSTVSDEVLSRLLHAAHAAPS
TH_1748|M.thermoresistible__bu -----------------------MRRFIPGTTISDDVLKRLMHAAHAAPN
Mflv_0353|M.gilvum_PYR-GCK -----MS-AETAALYDVINRRRDTRREFTGAPTDDEVLERVLLAAHAAPS
Mvan_0381|M.vanbaalenii_PYR-1 -----MSDDSAAALYDVINRRRDTRREFTGEPVAGDVLQRVLLAAHAAPS
MAB_3351c|M.abscessus_ATCC_199 -----------MDVYQAIATRRDVRAEFTGQVVDDATLMKLLQAAHRAPS
* ..* .* ::: *** **.
MMAR_0555|M.marinum_M VGLMQPWRFIRITDTGLRRRIHTLVDEERALTAGALG-ERAEEFLALKVE
MUL_1218|M.ulcerans_Agy99 VGLMQPWRFIRITDTGLRRRIHTLVDEERALTAGALG-ERAEEFLALKVE
Mb0314|M.bovis_AF2122/97 VGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALG-AREEEFLALKVE
Rv0306|M.tuberculosis_H37Rv VGLMQPWRFIRITDETLKRRIHALVDDERLLTAEALG-AREEEFLALKVE
MAV_4857|M.avium_104 VGLMQPWRFIRITDAALRRRIHALVEQERPRTAAALG-ERAQEFLALKVE
MSMEG_6053|M.smegmatis_MC2_155 VGLMQPWRFIRITDDTLRSRIHALVDEERVNTADALG-PRAQEFLALKVE
TH_1748|M.thermoresistible__bu VGLMQPWRFIRITDPDLRRAIHRLVDEERHHTAAALG-PRGEEFLALKVE
Mflv_0353|M.gilvum_PYR-GCK VGMSQPWDFVLVRSPETLRAFRDHVAGEREVFAAELSGERADVFDRIKIE
Mvan_0381|M.vanbaalenii_PYR-1 VGMSQPWDFILVRSPQTLTTFRDHVAAERETFAGELSGERAETFGRIKIE
MAB_3351c|M.abscessus_ATCC_199 VGNSQPWDFVVIREPGMLDDFAAHVALQRQRFADSLPEGRRNTFDPIKIE
** *** *: : . : * :* * * * : * :*:*
MMAR_0555|M.marinum_M GILECAELMVVALRDGRDG-HIFGRRTLPQMDLASVSCAIQNLWLAARAE
MUL_1218|M.ulcerans_Agy99 GILECAELMVVALRDGRDG-HIFGRRTLPQMDLASVSCAIQNLWLAARAE
Mb0314|M.bovis_AF2122/97 GILDCAELLVVALCDRRGS-YIFGRRTLPQMDLASVSCAIQNLWLAARSE
Rv0306|M.tuberculosis_H37Rv GILDCAELLVVALCDRRGS-YIFGRRTLPQMDLASVSCAIQNLWLAARSE
MAV_4857|M.avium_104 GILECAELLVVALGDDRDK-HVFGRRTLPQMDLASVSCAIQNLWLAARAE
MSMEG_6053|M.smegmatis_MC2_155 GIRECAELFVVALGEGRER-HVFGRRTLPNMDLASVSCAIQNMWLAARAE
TH_1748|M.thermoresistible__bu GILECAELLVVALGDDRER-HIFGRRTMPDMDLASVSCAIQNLWLAARAE
Mflv_0353|M.gilvum_PYR-GCK GICESGLGIVVGYDPTRGGPAVLGRHAIPDAGLYSVVCAIQNLWLAATAE
Mvan_0381|M.vanbaalenii_PYR-1 GICESGLGIVVGYDPTRAGPQVLGRHAVPDAGLYSVVCAIQNLWLAATVE
MAB_3351c|M.abscessus_ATCC_199 GIRESGTGVVVTYDHGRGGPHILGRHTISDAGLFSAVLAIQNLWLAAVTE
** :.. .** * ::**:::.: .* *. ****:**** *
MMAR_0555|M.marinum_M GLGMGWVSLFDPHRLADLLRMPDGAEPVAVLCLGPVPEFPQQPALELDGW
MUL_1218|M.ulcerans_Agy99 GLGMGWVSLFDPHRLADLLRMPDGAEPVAVLCLGPVPEFPQQPALELDGW
Mb0314|M.bovis_AF2122/97 GLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGW
Rv0306|M.tuberculosis_H37Rv GLGMGWVSLFDPQRLAALLAMPADAEPVAILCLGPVPEFPDRPALELDGW
MAV_4857|M.avium_104 GLGMGWVSLFEPRPLAELLGLPDGAEPVAILCLGPVPEFPDRPALELDGW
MSMEG_6053|M.smegmatis_MC2_155 GLGMGWVSIFEPQPLAELLGMPDGAEPVAILCLGPVPEFPDRPVLEIEHW
TH_1748|M.thermoresistible__bu GLGMGWVSLFEPRRLATLLDIPADAEPVAVLCLGPVPDFPDRPELEIENW
Mflv_0353|M.gilvum_PYR-GCK GLGVGWVSFYREETLRSLVGMPDHVRPVAWLCVGPVADLPDVPDLERFGW
Mvan_0381|M.vanbaalenii_PYR-1 GLGVGWVSFYREEFLRSLVGMPDHVRPVAWLCVGPVAELPDVPDLERFGW
MAB_3351c|M.abscessus_ATCC_199 GIGVGWVSFYEEQFLAELIDAPAHIRPIAWLCVGPVREFAERPDLERFGW
*:*:****:: . * *: * .*:* **:*** ::.: * ** *
MMAR_0555|M.marinum_M AVARPLPEFVSENRWDQP-----------
MUL_1218|M.ulcerans_Agy99 AVARPLPEFVSENRWDQP-----------
Mb0314|M.bovis_AF2122/97 AYARPLAEFVSENRWSYPSALATDHHHGE
Rv0306|M.tuberculosis_H37Rv AYARPLAEFVSENRWSYPSALATDHHHGE
MAV_4857|M.avium_104 ATPRPLAEFVCENRWAQPQLP--------
MSMEG_6053|M.smegmatis_MC2_155 TTGRPLPEFVSENGWPEHASV--------
TH_1748|M.thermoresistible__bu TVGRPLDEFVSENGWTDSGARA-------
Mflv_0353|M.gilvum_PYR-GCK QARRSLDTVVHRERYPEP-----------
Mvan_0381|M.vanbaalenii_PYR-1 RARSSLETVLHQECYRAR-----------
MAB_3351c|M.abscessus_ATCC_199 RTGRPLEDAVHWGRYRA------------
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