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VAKTSHRVSSADGMSKRILRLIIAQSGFYSAALQLGNVSIVLPFVVAELDAELWIAALIFPAFTAGGAIG NVVAPPAVAAVPRRHRLFIIVSCLAVLAGVNALCATIGKGSVAGILLVVNVTLIGVVSAISFVAFADLVA AMPSGTARARILLTEVGVGAALTAVVAATLSFVPDQHPLSRNIHLLWTAAVAMAISAAICRALPHRIVPR VHAAPGLHKLVYVGWTAIRTNGWYRRYLLVQVLFGSVVLGSSFHSIRVAAVPGDQPDEVVAVVLFVCVGL LGGIALWNRVRERFGLVGLFVGSALVSIAAAVLSIAFDLAGAWPNVVAIGLVIALVSIANQSVFTAGQLW IARDAEPGLRTSLISFGQLVINAGLVGMGLALGLIAQDHDAVWPVMIVLLLNLTAAYSATRFAPAKSVDV RGLPQVSRTSRPKTGG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv0246 | - | - | 100% (436) | PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN |
| M. tuberculosis H37Rv | Rv2209 | - | 9e-52 | 32.14% (420) | integral membrane protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0252 | - | 0.0 | 99.77% (436) | integral membrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_0508 | - | 1e-163 | 71.33% (415) | integral membrane protein |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_3398 | - | 1e-05 | 29.89% (184) | integral membrane transport protein |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3569 | - | 3e-44 | 31.41% (417) | hypothetical protein MUL_3569 |
| M. vanbaalenii PYR-1 | Mvan_1951 | - | 1e-06 | 22.10% (457) | major facilitator superfamily transporter |
CLUSTAL 2.0.9 multiple sequence alignment
Rv0246|M.tuberculosis_H37Rv --------------------MAKTSHRVSSADGMSKRILRLIIAQSGFYS
Mb0252|M.bovis_AF2122/97 --------------------MAKTSHRVSSADGMSKRILRLIIAQSGFYS
MMAR_0508|M.marinum_M --------------------MVETSRPEGRIDGPSKRVLWLVITQSGFYR
MUL_3569|M.ulcerans_Agy99 --------------------------------------------------
Mvan_1951|M.vanbaalenii_PYR-1 MTSHTEGECPGADARSNSGTADAKSSSQSATKQPLPREVWVLVAAN--FV
MSMEG_3398|M.smegmatis_MC2_155 -----------------MNRVTDEAVELSGSDARRIAFAAFVGTALEWYD
Rv0246|M.tuberculosis_H37Rv AALQLGNVSIVLPFVVAELDAELWIAALIFPAFTAG---GAIGNVVAPPA
Mb0252|M.bovis_AF2122/97 AALQLGNVSIVLPFVVAELDAELWIAALIFPAFTAG---GAIGNVVAPPA
MMAR_0508|M.marinum_M TALQLGNVPIVLPFVVAELHAELWMAALIFPAFTAG---AAIGNMLAPAV
MUL_3569|M.ulcerans_Agy99 --MQMGSGAVVLP-VICAHQGLTWVAGLLFPAFSIG---AILGNSVSPLI
Mvan_1951|M.vanbaalenii_PYR-1 VALGYGVVAPVLPQYARHFGVSISAATFVITAFAVM---RLVGAPPAGML
MSMEG_3398|M.smegmatis_MC2_155 YFLFGTAAALVFNRLFFTDLDPAAATLASFATFGVGFAARPIGAVIFGYI
: . *: : :.:* :*
Rv0246|M.tuberculosis_H37Rv VAAVPRRHRLFIIVSCLAVLAGVN---ALCATIGKGSVAGILLVVNVTLI
Mb0252|M.bovis_AF2122/97 VAAVPRRHRLFIIVSCLAVLAGVN---ALCATIGKGSVAGILLVVNVTLI
MMAR_0508|M.marinum_M LAAVPRRRRLVIIVFGLTVLAAVN---AMGATMGDGNEAGSLFLVNVLFI
MUL_3569|M.ulcerans_Agy99 LQRFGQYRHLLMAAISASAATLIL---ANAAVPWTGALVAAVFFVTATAS
Mvan_1951|M.vanbaalenii_PYR-1 VQRLGERRVYISGLIIVALSTAAC---AFAETYWQ-----LLLFRSLGGI
MSMEG_3398|M.smegmatis_MC2_155 GDRYGRRPALLATIIMIGCATGLVGVLPDYAAVGIAAPAMLAILRLVQGL
. . : . . :.
Rv0246|M.tuberculosis_H37Rv GVVSAISFVAFADLVAAMPSGTARARILLTEVGVGAALTAVVAATLS-FV
Mb0252|M.bovis_AF2122/97 GVVSVISFVAFADLVAAMPSGTARARILLTEVGVGAALTAVVAATLS-FV
MMAR_0508|M.marinum_M GAVSAFSFVAFADLVAAMPSGTDRAQVLLTEAGVGAALTAIVTVALS-FV
MUL_3569|M.ulcerans_Agy99 GVVAGVSGVAYTDMVSNKLSVLRRGELLLTQGAFGSLLATGVTLVIVPRL
Mvan_1951|M.vanbaalenii_PYR-1 GSAMFTVSSLGLMIRISPPDARGRVAGLFSSGFMVGSVGGPILGALTAGF
MSMEG_3398|M.smegmatis_MC2_155 AVGGEWGGATTMAIEHSPIKQRGRFAALVQIGSPVGTLVSSGAFALVLML
. : . * *. . : .: .
Rv0246|M.tuberculosis_H37Rv PDQHPLSRNIHLLWTAAVAMAIS--AAICRALPHRIVPRVHAAPGLHKLV
Mb0252|M.bovis_AF2122/97 PDQHPLSRNIHLLWTAAVAMAIS--AAICRALPHRIVPRVHAAPGLHKLV
MMAR_0508|M.marinum_M PHEDHLTNNIRLLWTATAAMAIS--GLICLGLPQRIVPPVHKAPGLNKVV
MUL_3569|M.ulcerans_Agy99 AHGDEMARYHDLLWLGAASMIVAGVAALFVGPMRSASSAPTVRLPLRDIY
Mvan_1951|M.vanbaalenii_PYR-1 GLSAPFLIYGAALLVAATVVFVS---LRHSTVVGQQDEDPEEPVPFRTVF
MSMEG_3398|M.smegmatis_MC2_155 PSESFDSWGWRLPFLAAFPLLGVALWIRLTMEESPVFKRLAELEAAAEVP
.: : :
Rv0246|M.tuberculosis_H37Rv YVGWTAIRTNGWYRRYLLVQVLFGSVVLGSSFHSIRVAAVPGDQPDEVVA
Mb0252|M.bovis_AF2122/97 YVGWTAIRTNGWYRRYLLVQVLFGSVVLGSSFHSIRVAAVPGDQPDEVVA
MMAR_0508|M.marinum_M HVGLAALRRESWYRRYLAVQLLFGSVVLGSSFYSIRVAAIPGDEHDNVVV
MUL_3569|M.ulcerans_Agy99 RQGFEIARREPWFRRYATTYLLFAPISLGTTFFSLRAAQSSG----SLHV
Mvan_1951|M.vanbaalenii_PYR-1 RH---RAYRAALFSNFATGWASFG---LRIALVPLFIVEVLGQSPGAAGL
MSMEG_3398|M.smegmatis_MC2_155 VLQLVRNAGGRLLVAVAAALLGVGGFYIMTTFVVSYGSNVLAVDRQVMVN
.. : :: .
Rv0246|M.tuberculosis_H37Rv VVLFVCVGLLGGIALWNRVRERFGLVGLFVGSALVSIAAAVLSIAFDLAG
Mb0252|M.bovis_AF2122/97 VVLFVCVGLLGGIALWNRVRERFGLVGLFVGSALVSIAAAVLSIAFDLAG
MMAR_0508|M.marinum_M LVLFVCVGLVGGIRVWNRIRERFGLVGLFAGSAILSIAAAVIAIAFQLAG
MUL_3569|M.ulcerans_Agy99 LVILSSIAFVIGSLLWRAVNRRFGVRGMLLGSSLFSIAAALVCIVAELCG
Mvan_1951|M.vanbaalenii_PYR-1 ALTAFAVGNISVVIPSGHLSDRLGRR------KLMIFGLTLAAASTALVG
MSMEG_3398|M.smegmatis_MC2_155 ATLVAAVLQIAVTIFAGRLSERFGPGR---MTVAGAVTTAIAAFPLFWLI
.: : : *:* . :: .
Rv0246|M.tuberculosis_H37Rv AWPNVVAIGLVIALVSIANQSVFTAGQLWIARDAEPGLR-TSLISFGQLV
Mb0252|M.bovis_AF2122/97 AWPNVVAIGLVIALVSIANQSVFTAGQLWIARDAEPGLR-TSLISFGQLV
MMAR_0508|M.marinum_M SWPNLVAISLVIALASIANQSVFTAGQLWIAHNADPTLR-ISLIAFGRLV
MUL_3569|M.ulcerans_Agy99 QWTQMWAYGTAFLLATVAAQTVVAASISWISMFAPEQHR-ATLICFGATL
Mvan_1951|M.vanbaalenii_PYR-1 FTTSLPVFLVAAYIAGAATGIFVSPQQAAVADVVGNKSRGGTAVATFQMM
MSMEG_3398|M.smegmatis_MC2_155 DTRNAWAITAAVACGIALITLAYAVTGALLAELFPPALRYSGVSLGYNLA
. . . : :: *
Rv0246|M.tuberculosis_H37Rv INAGLVGMGLALGLIAQDHDAVWPVMIVLL-LNLTAAYSATRFAPAKSVD
Mb0252|M.bovis_AF2122/97 INAGLVGMGLALGLIAQDHDAVWPVMIVLL-LNLTAAYSATRFAPAKSVD
MMAR_0508|M.marinum_M ISAGLVGLSSLLGILAQFHDVVWPVMIVLL-LNVAAAYSAKRLAPAD---
MUL_3569|M.ulcerans_Agy99 AAVVSTLLGAVLGELAQRHATIGPVLVSLT-LAIIAAVASLRAPGLSQTI
Mvan_1951|M.vanbaalenii_PYR-1 ADFGSIGGSLLVGLIAQYTSFGWAFLISGV-ILAVAAVGWIFAPETRPRA
MSMEG_3398|M.smegmatis_MC2_155 GALSGFLPLIATALLAVGDGASWPAALVLIGICAITAIGGLAGERMRLRH
. :* . : : :* .
Rv0246|M.tuberculosis_H37Rv VRGLPQVSRTSRPKTGG---------------------------------
Mb0252|M.bovis_AF2122/97 VRGLPQVSRTSRPKTGG---------------------------------
MMAR_0508|M.marinum_M --------------------------------------------------
MUL_3569|M.ulcerans_Agy99 EAQSQLVDKAPMRRLSRARRGAHRLVTGTAPGLGLALTRHTAADRRGRYP
Mvan_1951|M.vanbaalenii_PYR-1 STEHTQARPLGPEAGGEVP-------------------------------
MSMEG_3398|M.smegmatis_MC2_155 DPVEHQPATS----------------------------------------
Rv0246|M.tuberculosis_H37Rv -----------------------------------
Mb0252|M.bovis_AF2122/97 -----------------------------------
MMAR_0508|M.marinum_M -----------------------------------
MUL_3569|M.ulcerans_Agy99 SLRRAHRRPAPSPIRPGCHASAHRPEPGNLATVLT
Mvan_1951|M.vanbaalenii_PYR-1 -----------------------------------
MSMEG_3398|M.smegmatis_MC2_155 -----------------------------------