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M. tuberculosis H37Rv Rv0235c (-)

annotation: PROBABLE CONSERVED TRANSMEMBRANE PROTEIN
coordinates: 281166 - 282614
length: 482

GWFSAPEYWLGRLALERGTAIIYLIAFVAAAQQFRPLIGEHGMLPVPRYLAGQSFWRTPSIFHFRYSDRV
FAGVCWLGAVLSAAVVAGAASFVPLWATMLIWLTLWVLYLSIVNVGQAWYSFGWESLLLETGFLMIFLGN
ERTAPPILTLLLARWLLFRVEFGAGLIKMRGDSCWRSLTCLYYHHETQPMPGPLSWFFHHLPKPLHRIEV
AGNHFAQLVVPFGLFTPQPAASIAAAIIVVTQLWLVASGNFSWLNWLTILLACSAIDTSSAAALLPMPAQ
PALSAPPQWFAGLVVVFTAAVLLLSYWPARNLLSSHQRMNMSFNPFHLVNTYGAFGSICRTRREVVIEGT
DESPITEQTVWKAYEFKGKPGDPRRLPRQWAPYHLRLDWLMWFAAISPGYALPWMTPFLNRLLRNDPATL
KLLRHNPFPQSPPRYVRAQLYQYRFTTVAELRRDRAWWHRTLIGRYVPPMSLRKVASPPAD*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv0235c--100% (482)PROBABLE CONSERVED TRANSMEMBRANE PROTEIN

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0240c-0.0100.00% (482) transmembrane protein
M. gilvum PYR-GCK-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_0493-0.081.18% (473) hypothetical protein MMAR_0493
M. avium 104MAV_4924-0.079.75% (479) integral membrane protein
M. smegmatis MC2 155MSMEG_1761-0.070.00% (430) integral membrane protein
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_1156-0.079.37% (475) hypothetical protein MUL_1156
M. vanbaalenii PYR-1Mvan_4797-0.071.40% (479) hypothetical protein Mvan_4797

CLUSTAL 2.0.9 multiple sequence alignment


Rv0235c|M.tuberculosis_H37Rv        --MGWFSAPEYWLGRLALERGTAIIYLIAFVAAAQQFRPLIGEHGMLPVP
Mb0240c|M.bovis_AF2122/97           --MGWFSAPEYWLGRLALERGTAIIYLIAFVAAAQQFRPLIGEHGMLPVP
MMAR_0493|M.marinum_M               --MEWFSASEYWLGRLVLERGVAAVYLTAFVASALQFRALIGEHGMLPVP
MUL_1156|M.ulcerans_Agy99           --MEWFSASEYWLGRLVLERGVAAVYLTAFVASALQFRALIGEHGMLPVP
MAV_4924|M.avium_104                --MSWFSAPDYWVGRLVLERGVAVIYLLAFVAAAAQFRALIGEHGMLPIP
Mvan_4797|M.vanbaalenii_PYR-1       MYADWFDAPGYWLAREVLQRGVAAIYLIAFVAAARQFRALIGEHGMLPVP
MSMEG_1761|M.smegmatis_MC2_155      ----------------------------------------------MPIP
                                                                                  :*:*

Rv0235c|M.tuberculosis_H37Rv        RYLAGQSFWRTPSIFHFRYSDRVFAGVCWLGAVLSAAVVAGAASFVPLWA
Mb0240c|M.bovis_AF2122/97           RYLAGQSFWRTPSIFHFRYSDRVFAGVCWLGAVLSAAVVAGAASFVPLWA
MMAR_0493|M.marinum_M               RYLAHRSFWRTPSVFHFRYSDRLFAGVCWLGAALSAAVVGGTADLVPLWG
MUL_1156|M.ulcerans_Agy99           RYLAHRSFWRTPSVFHFRYSDRLCAGVCWLDAALSAAVVGGTADLVPLWG
MAV_4924|M.avium_104                RFLAGQSWRRTPSIFHLHYSDRLFAALSWFGAALSAAIVAGAADAVPLWA
Mvan_4797|M.vanbaalenii_PYR-1       RFVAQVPFRVAPSVFHLHYSDRFFSAVCWSGAVLATAVAAGGDDLVPLWA
MSMEG_1761|M.smegmatis_MC2_155      RFLARSSFRNSPSIFHLHYSDRFFAAVCWTGAAVAAAMVLGAGDRLPLWA
                                    *::*  .:  :**:**::****. :.:.* .*.:::*:. *  . :***.

Rv0235c|M.tuberculosis_H37Rv        TMLIWLTLWVLYLSIVNVGQAWYSFGWESLLLETGFLMIFLGNERTAPPI
Mb0240c|M.bovis_AF2122/97           TMLIWLTLWVLYLSIVNVGQAWYSFGWESLLLETGFLMIFLGNERTAPPI
MMAR_0493|M.marinum_M               AMLMWLTLWVLYLSIVNVGQVWYGFGWESLLLETGFLMVFLGNDRVAPPL
MUL_1156|M.ulcerans_Agy99           GMLMWLTLWVLYLSIVNVGQVWYGFGWESLLLETGFLVVFLGNDRVAPPL
MAV_4924|M.avium_104                AMLMWLTLWVLYLSIVNVGQTWYSFGWESLLLETGFLMIFLGNAEVAPPL
Mvan_4797|M.vanbaalenii_PYR-1       ATLAWLALWVLYLSIVNVGQRWYGFGWESLLLEAGFLAMLLGNDDTAPPL
MSMEG_1761|M.smegmatis_MC2_155      AMLVWVLLWVLYLSIVNVGQAWYSFGWESLLLEAGTLAVFLGNDDVAPPL
                                      * *: ************* **.*********:* * ::***  .***:

Rv0235c|M.tuberculosis_H37Rv        LTLLLARWLLFRVEFGAGLIKMRGDSCWRSLTCLYYHHETQPMPGPLSWF
Mb0240c|M.bovis_AF2122/97           LTLLLARWLLFRVEFGAGLIKMRGDSCWRSLTCLYYHHETQPMPGPLSWF
MMAR_0493|M.marinum_M               VMLWLVRWLLFRVEFGAGLIKMRGDACWRNLTCLYYHHETQPMPGPLSWF
MUL_1156|M.ulcerans_Agy99           VMLWLVRWLLFRVEFGAGLIKMRGDACWRNLTCLYYHHETQPMPGPLSWF
MAV_4924|M.avium_104                LTLWMARLLLFRVEFGAGLIKMRGDPCWRDLTCLYYHHETQPMPGPLSWF
Mvan_4797|M.vanbaalenii_PYR-1       LALWLARWLLFRVEFGAGLIKMRGDPCWRDLSCLDYHHETQPMPGPLSWF
MSMEG_1761|M.smegmatis_MC2_155      LVLWLVRWLLFRVEFGAGMIKMRGDRCWRDLTCLYYHHETQPMPGPLSWF
                                    : * :.* **********:****** ***.*:** ***************

Rv0235c|M.tuberculosis_H37Rv        FHHLPKPLHRIEVAGNHFAQLVVPFGLFTPQPAASIAAAIIVVTQLWLVA
Mb0240c|M.bovis_AF2122/97           FHHLPKPLHRIEVAGNHFAQLVVPFGLFTPQPAASIAAAIIVVTQLWLVA
MMAR_0493|M.marinum_M               FHRMPRPLHRIEVAGNHFAQLVVPFGLFAPQPIASIAAVIIIVTQLWLVM
MUL_1156|M.ulcerans_Agy99           VHRMPRPLHRIEVAGNHFAQLVVPFGLFAPQPIASIAAVIIIVTQLWLVM
MAV_4924|M.avium_104                FHHLPKPLHRIEVAGNHFAQLIVPFGLFAPQPVAGVAAAIIVVTQLWLVA
Mvan_4797|M.vanbaalenii_PYR-1       FHHLPKPLHRVEVAGNHVAQLVVPFALFAPQPVASVAAGIVIVTQLWLVL
MSMEG_1761|M.smegmatis_MC2_155      FHHLPKPLHRVEVAGNHVAQLVIPFLLFAPQPVASTAAAVVIVTQLWLVA
                                    .*::*:****:******.***::** **:*** *. ** :::******* 

Rv0235c|M.tuberculosis_H37Rv        SGNFSWLNWLTILLACSAIDTSSAAALLP---MPAQPALSAPPQWFAGLV
Mb0240c|M.bovis_AF2122/97           SGNFSWLNWLTILLACSAIDTSSAAALLP---MPAQPALSAPPQWFAGLV
MMAR_0493|M.marinum_M               SGNFSWLNWLTILLACSAIEQSAARKVLP---IPVRAALPPPPTWFAALV
MUL_1156|M.ulcerans_Agy99           SGNFSWLNWLTILLACSAIEQSAARKVLP---IPVRAALPPPPTWFAALV
MAV_4924|M.avium_104                SGNFAWLNWVTILLACSAIDDSSVALLLPKSVLPGQGEPSASPLWFVVVV
Mvan_4797|M.vanbaalenii_PYR-1       SGNFAWLNWLTILLAFSAVDQSVFAVVLP---MSAPPARAGPPPWFAALV
MSMEG_1761|M.smegmatis_MC2_155      SGNFAWLNWITIVLACGVVSDTALSAVVG---VSAAPDVGDPPVWYVAAV
                                    ****:****:**:** ..:. :    ::    :.       .* *:.  *

Rv0235c|M.tuberculosis_H37Rv        VVFTAAVLLLSYWPARNLLSS--HQRMNMSFNPFHLVNTYGAFGSICRTR
Mb0240c|M.bovis_AF2122/97           VVFTAAVLLLSYWPARNLLSS--HQRMNMSFNPFHLVNTYGAFGSICRTR
MMAR_0493|M.marinum_M               LIFAATVLVLSYWPARNMLSP--RQRMNMSFNPLHLVNTYGAFGSICRTR
MUL_1156|M.ulcerans_Agy99           LIFAATVLVLSYWPARNMLSPPPRQRMNMSFNPVHLVNTYGAFGSICRTR
MAV_4924|M.avium_104                VAVTAAVLVMSYWPIRNMLSS--RQRMNMSFNSFHLVNTYGAFGSIGRVR
Mvan_4797|M.vanbaalenii_PYR-1       IAGTALTVVLSYWPVRNMLGR--RQQMNASFNPFHLVNTYGAFGSIGRVR
MSMEG_1761|M.smegmatis_MC2_155      VAFTAMVVSLSFWPLRNLVTK--RQRMNMSYNRYHLVNSYGAFGVVGRTR
                                    :  :* .: :*:** **::    :*:** *:*  ****:***** : *.*

Rv0235c|M.tuberculosis_H37Rv        REVVIEGTDESPITEQTVWKAYEFKGKPGDPRRLPRQWAPYHLRLDWLMW
Mb0240c|M.bovis_AF2122/97           REVVIEGTDESPITEQTVWKAYEFKGKPGDPRRLPRQWAPYHLRLDWLMW
MMAR_0493|M.marinum_M               REVVIEGTSEAELNAQTVWQEYEFKGKPGRVGRLPRQWAPYHLRLDWLMW
MUL_1156|M.ulcerans_Agy99           REVVVEGTSEAELNAQTVWQEYEFKGKPGRVGRLPRQWAPYHLRLDWLMW
MAV_4924|M.avium_104                REVVIEGTADDDITDQTVWWEYEFKGKPGGVRRLPRQWAPYHLRLDWLMW
Mvan_4797|M.vanbaalenii_PYR-1       YEVVIEGTAEPEPTAQTVWKEYGFKGKPGDLRRMPRQWAPYHLRLDWMMW
MSMEG_1761|M.smegmatis_MC2_155      DEVVIEGTDEPTINDETTWREYEFKGKPGDVRRLPRQFAPYHLRLDWLMW
                                     ***:*** :   . :*.*  * ******   *:***:*********:**

Rv0235c|M.tuberculosis_H37Rv        FAAISPGYALPWMTPFLNRLLRNDPATLKLLRHNPFPQSPPRYVRAQLYQ
Mb0240c|M.bovis_AF2122/97           FAAISPGYALPWMTPFLNRLLRNDPATLKLLRHNPFPQSPPRYVRAQLYQ
MMAR_0493|M.marinum_M               FAAISPGYALPWMTPLLTRLLRNDRATLRLLRRNPFPDTPPRYVRAQLYQ
MUL_1156|M.ulcerans_Agy99           FAAISPGYALPWMTPLLTRLLRNDRATLRLLRRNPFPDTPPRYVRAQLYQ
MAV_4924|M.avium_104                FAAISPGYAQPWLSPFLQRLLENDRPTLRLLRHNPFPDAPPRYVRARLYE
Mvan_4797|M.vanbaalenii_PYR-1       FAALSPAYARDWFRPLVVRLLRNDAATLRLLGHNPFPDEPPRCIRARLYE
MSMEG_1761|M.smegmatis_MC2_155      FAAISPTYAHPWLRTFLERLLEGDRATLKLLRTNPFPGEPPRYVRARLYR
                                    ***:** **  *: .:: ***..* .**:**  ****  *** :**:**.

Rv0235c|M.tuberculosis_H37Rv        YRFTTVAELRRDRAWWHRTLIGRYVPPMSLRKVASPPAD
Mb0240c|M.bovis_AF2122/97           YRFTTVAELRRDRAWWHRTLIGRYVPPMSLRKVASPPAD
MMAR_0493|M.marinum_M               YRFTTLQELRRDHAWWHRTLIGKYAAPMSLD--------
MUL_1156|M.ulcerans_Agy99           YPFTTLQELRRHHAWWHRTLIGKYAAPMSLD--------
MAV_4924|M.avium_104                YRFTTPAELRRDRDWWHRTLIGGYVPPLTLSKLTPQDHG
Mvan_4797|M.vanbaalenii_PYR-1       YRFTTWRELRDERRWWHRTLVGEYLPAVALGAGDSPAAR
MSMEG_1761|M.smegmatis_MC2_155      YRYSTWDELRRDHVWWQRTLLGDYVPPVTLRAGHGSAAQ
                                    * ::*  *** .: **:***:* * ..::*