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SRFQFVADHLHAFEVKWLCAGVEVARSSFYAWLAGAEGRAARKAADEALAARIRMVHDEDNTYGAPRITA ELNDSVPDGERVNHKRVARVMRDAGIAGYRRRRRVKTTTPDPAKQKVPDLLKRDFTAPAPNEKYVGDITY LPLATGSNLYMATVIDCFSGRVAGWAIAEHMRTELVEDALKAADALRGSLAGAVFHSDHGSQYTSTDFAS LCEKLGVTQSMGGVGSSADNALAESFNASLKREVLQDRSHWPDSATCRRQVFRWLVRYNLRRLGFP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3741 | - | - | 100% (277) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0583 | - | e-158 | 100.00% (273) | integrase catalytic subunit |
| M. vanbaalenii PYR-1 | Mvan_0575 | - | e-158 | 100.00% (273) | integrase catalytic subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2838c | - | 2e-33 | 34.88% (258) | transposase |
| M. gilvum PYR-GCK | Mflv_0608 | - | 1e-133 | 84.25% (273) | integrase catalytic subunit |
| M. tuberculosis H37Rv | Rv3475 | - | 2e-34 | 33.91% (289) | transposase IS6110 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2088 | - | 7e-28 | 32.94% (252) | transposase |
| M. marinum M | MMAR_2548 | - | 6e-33 | 35.00% (260) | transposase, ISMyma03_aa2 |
| M. avium 104 | MAV_1454 | - | 1e-38 | 38.82% (255) | transposase |
| M. smegmatis MC2 155 | MSMEG_1721 | - | 9e-34 | 34.14% (290) | IS1137, transposase orfB |
| M. thermoresistible (build 8) | TH_4372 | - | 3e-36 | 39.60% (250) | PUTATIVE Integrase, catalytic region |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3741|M.vanbaalenii_PYR-1 ----------------------------------------------MSRF
Mflv_0608|M.gilvum_PYR-GCK ----------------------------------------------MSRF
TH_4372|M.thermoresistible__bu ----------------------------------------------VSRF
MMAR_2548|M.marinum_M --------------------------------------------------
MSMEG_1721|M.smegmatis_MC2_155 ------------------------------------MEFISAHQHMRVGV
Mb2838c|M.bovis_AF2122/97 --------------------------------------------------
Rv3475|M.tuberculosis_H37Rv AEALAAGQRRIAKGERDFKDRVGFLRGRARPASTLITRFIADHQGHREGP
MAV_1454|M.avium_104 --------------------------------------------------
MAB_2088|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_3741|M.vanbaalenii_PYR-1 QFVADHLHAFEVKWLCAGVEVARSSFYAWLAG--AEGRAARKAADEALAA
Mflv_0608|M.gilvum_PYR-GCK QFVADHLHAFEVKWLCAVVEVARSSFYAWLAG--ADGRAARRAADEALAE
TH_4372|M.thermoresistible__bu ELIAAECAHHDVSKLAELLGVSRSGYYAWAARQRRVELSPRQQWRRDLEV
MMAR_2548|M.marinum_M ------------MLTEHGIKISPSTYYEWMKRT-PSKQQLR---DEAVTA
MSMEG_1721|M.smegmatis_MC2_155 DGLKWGVESMCAVLSEYGVTIAPSTYYAHRARQGPSKADWA---DAQVID
Mb2838c|M.bovis_AF2122/97 ------------------MPIAPSTYYDHINRE-PSRRELR---DGELKE
Rv3475|M.tuberculosis_H37Rv DGLRWGVESICTQLTELGVPIAPSTYYDHINRE-PSRRELR---DGELKE
MAV_1454|M.avium_104 --------------------MALSTYYDTKARV-PSARALR---DAVLGP
MAB_2088|M.abscessus_ATCC_1997 -------------MTRRVLKLARQPYYRWRANP----ITDAELVEAYRAN
:: . :*
Mvan_3741|M.vanbaalenii_PYR-1 RIRMVHDED---NTYGAPRITAELNDSVPDGERVNHKRVARVMRDAGIAG
Mflv_0608|M.gilvum_PYR-GCK RIRAVHDED---NTYGAPRITAELNDGAPEGQRVNHKRVARVMRGAGIAG
TH_4372|M.thermoresistible__bu KILAHWQASG--RTYGSPRITADLHA---EGVGVSENTVAKIMAEMGIEG
MMAR_2548|M.marinum_M SIKEFRERNPLNKTLGSRKVWIKLRG---DGMDVARCTVERLMQANRWQG
MSMEG_1721|M.smegmatis_MC2_155 AIWQLRQSQSLYRVLGARKTWIVLRT---NGIDVSRCVVERVMREMGWRG
Mb2838c|M.bovis_AF2122/97 HISRVHAAN--YGVYGARKVWLTLNR---EGIEVARCTVERLMTKLGLSG
Rv3475|M.tuberculosis_H37Rv HISRVHAAN--YGVYGARKVWLTLNR---EGIEVARCTVERLMTKLGLSG
MAV_1454|M.avium_104 ALCQLWKDN--YCVYGARKLWKTARR---EGHDVGRDQVARLMRAAGIEG
MAB_2088|M.abscessus_ATCC_1997 ALFDAHGED---PEFGYRYLVEEARE---AGEPMAERTAWRICSQQQLWS
: . * . * : . . :: .
Mvan_3741|M.vanbaalenii_PYR-1 YR-RRRRVKTTTPDPAKQKVPDLLKRDFTAPAPNEKYVGDITYLPLATGS
Mflv_0608|M.gilvum_PYR-GCK YR-RRRRVKTTVADPANQKVPDLLKRDFTAAQVNTRYVGDITYLPLATGA
TH_4372|M.thermoresistible__bu ISPRTFKVKTTQVDPTASFPPDRVGRAFDQGRLDAVWTSDITYLTCGEGD
MMAR_2548|M.marinum_M AR-YGGAPKTTIQDEKAQRATDLVDRVFAAPAPNRLWVADFTYCPTWAGM
MSMEG_1721|M.smegmatis_MC2_155 AC-KRRRVRTTVADPAATRAPDRVRRNFVAGAPDRLWVADFTYCRTRAGW
Mb2838c|M.bovis_AF2122/97 TT-RGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGF
Rv3475|M.tuberculosis_H37Rv TT-RGKARRTTIADPATARPADLVQRRFGPPAPNRLWVADLTYVSTWAGF
MAV_1454|M.avium_104 VR-RGKRVRTTKPDPAAARHPDLVKRNFTATAPNQLWVTDLTFVPTWAGV
MAB_2088|M.abscessus_ATCC_1997 VF---GKKRGKNGKPGPPVHDDLVQRDFTAETPNMLWLSDITEHYTGDGK
: . . * : * * : : *:* *
Mvan_3741|M.vanbaalenii_PYR-1 NLYMATVIDCFSGRVAGWAIAEHMRTELVEDALKAADALRG-----SLAG
Mflv_0608|M.gilvum_PYR-GCK NLYLATVIDCCSRRVAGWAIADHMRTELVIDALKAAAALRG-----SLAG
TH_4372|M.thermoresistible__bu -AYLCAIRDEHSRRVLGWSLADHMRTELVEAAVDAAVFTRAG----HVAG
MMAR_2548|M.marinum_M -VYVAFVIDAFARRVIGWRAATSMKTALVIDALEHAFFTRAQEGFTDLSG
MSMEG_1721|M.smegmatis_MC2_155 -AYTAFVTDVYARKIVGWKVATEMTQKLVTDAIDHAIDTRKRSGAASLDS
Mb2838c|M.bovis_AF2122/97 -AYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKD
Rv3475|M.tuberculosis_H37Rv -AYVAFVTDAYARRILGWRVASTMATSMVLDAIEQAIWTRQQEGVLDLKD
MAV_1454|M.avium_104 -AYVCFIIDAYSRMIVGWRVASHMRTSMVLDALEMARWSRGN----MLPG
MAB_2088|M.abscessus_ATCC_1997 -LYLCAIKDAFSNRIVGYSIDSRMKSRLATAALRNAVGRRG-----VVAG
* . : * : : *: * :. *: * * : .
Mvan_3741|M.vanbaalenii_PYR-1 AVFHSDHGSQYTSTDFASLCEKLGVTQSMGGVGSSADNALAESFNASLKR
Mflv_0608|M.gilvum_PYR-GCK AIFHADHGSQYTSRDFANLCRDLGVVQSMGAVGSSADNALAESFNAALKR
TH_4372|M.thermoresistible__bu TVMHSDRGSQFTSYDMAQACTRHGLLRSMGATGICWDNAGSESLWSTVKH
MMAR_2548|M.marinum_M LVAHSDAGSQYTSIAFTTRLIDAGIDASVGSVADAYDNALAETTVGSFKN
MSMEG_1721|M.smegmatis_MC2_155 LIHHSDAGSQYTAVAFTERLAAEGILPSVGSVGDSFDNALAESVNSSYKT
Mb2838c|M.bovis_AF2122/97 VIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKT
Rv3475|M.tuberculosis_H37Rv VIHHTDRGSQYTSIRFSERLAEAGIQPSVGAVGSSYDNALAETINGLYKT
MAV_1454|M.avium_104 LRCHSDAGSQFTSIRYGERLAEIGAVPSIGTVGDSFDNALAETVNGYYKA
MAB_2088|M.abscessus_ATCC_1997 CVVHTDRGSQFRSRKFVQALHHHGMVGSMGRVGAAGDNAAMESFFSLLQK
*:* ***: : * *:* .. . *** *: . :
Mvan_3741|M.vanbaalenii_PYR-1 EVLQD---RSHWPDSATCRRQVFRWLV-RYN-LRRLGFP-----------
Mflv_0608|M.gilvum_PYR-GCK EILQD---RACWPDAAICRREVFRWLA-RYNTTRRHSYCRHSSPATYERN
TH_4372|M.thermoresistible__bu EYYK----RHAFTTYANLTAGLDNYIR-FYNHERRHSSLGMISPIDFDLS
MMAR_2548|M.marinum_M ELIR---RQGPWRDVDHVEIGTLNWVD-WFNNERPHEYLADLTPTQAEAL
MSMEG_1721|M.smegmatis_MC2_155 ELID---RQPLYPGATELALGTAEWVA-FYNRQRPNGYCQDLTPDRAEAL
Mb2838c|M.bovis_AF2122/97 ELIK-PGK--PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAA
Rv3475|M.tuberculosis_H37Rv ELIK-PGK--PWRSIEDVELATARWVD-WFNHRRLYQYCGDVPPVELEAA
MAV_1454|M.avium_104 ELIYGPARTGPWKTVEDVELATLSWVY-WHNTSRLHSYLGDIPPAEFEAA
MAB_2088|M.abscessus_ATCC_1997 NVLD----RRRWATREELRIAIVTWIERTYHRRRRQGALGRLTPVEYEAI
: : :: .: *
Mvan_3741|M.vanbaalenii_PYR-1 ---------------
Mflv_0608|M.gilvum_PYR-GCK LTPATLPEAA-----
TH_4372|M.thermoresistible__bu LDILLSTQV------
MMAR_2548|M.marinum_M HYRHKSSLAAAG---
MSMEG_1721|M.smegmatis_MC2_155 YYHRQRHPHAEEALR
Mb2838c|M.bovis_AF2122/97 YYAQR--QRPAAG--
Rv3475|M.tuberculosis_H37Rv YYAQR--QRPAAG--
MAV_1454|M.avium_104 FYDAYRTDQPLIGIQ
MAB_2088|M.abscessus_ATCC_1997 MTTTASQAA------