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MDLSRIHALGDRDRTLAALLDIVGDSHVVAIGEGAHFVAEYWQCRRHLVELLHRHAGFQLVAMEFGVGEA LQLTSWLSGDAGDDGDADLSSISPAAVEWGAGDTMVWLRHFNAAAAARGVPPLRFAGIDLPSAGGAFTPA LTPLETYLHDCDPELASTLDDVRAITGVVEGGSGVSAARRWSELDQSTRDAAIAGLARIVLRMTALRQRY ETRDAGRDHRTALLLGHSALATAYMLQATAEAVAGDGMPLDSSVRERFLADAVLALRETGDDKVVVLAHN NHVQKTPVVFAGTTYTLPMGSYLAGTLGDDYRVIAQTTTDDHVPDMVLDPAGSVGFRVIDAQLPEPAAGT FEHALLTAAAAQQPTLTDVRPCPKYAPPQGLRSQSAVVDTDVSAAFDAVVNHPRVTRQPDVHF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5893 | - | - | 100% (413) | erythromycin esterase |
| M. vanbaalenii PYR-1 | Mvan_1393 | - | 9e-12 | 24.70% (332) | erythromycin esterase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2056c | - | 4e-09 | 25.91% (328) | hypothetical protein Mb2056c |
| M. gilvum PYR-GCK | Mflv_4988 | - | 9e-14 | 26.89% (331) | erythromycin esterase |
| M. tuberculosis H37Rv | Rv2030c | - | 4e-09 | 25.91% (328) | hypothetical protein Rv2030c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_3483 | - | 4e-12 | 25.53% (333) | hypothetical protein MMAR_3483 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2056c|M.bovis_AF2122/97 MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGG
Rv2030c|M.tuberculosis_H37Rv MLMTAAADVTRRSPRRVFRDRREAGRVLAELLAAYRDQPDVIVLGLARGG
MMAR_3483|M.marinum_M --MTSAARADRNAPRRVFRDRHEAGQVLADLLTAYRDRPDVIVLGLARGG
Mflv_4988|M.gilvum_PYR-GCK --MTTARRAASDQPRRVFRDRREAGQALAGLLGGYRGRENVVVLGLARGG
Mvan_5893|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2056c|M.bovis_AF2122/97 LPVAWEVAAALHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVR
Rv2030c|M.tuberculosis_H37Rv LPVAWEVAAALHAPLDAFVVRKLGAPGHDEFAVGALASGGRVVVNDDVVR
MMAR_3483|M.marinum_M IPVAWEVAAALHAPLDAFIVRKLGAPGHEEFAVGALASGGRVVVNDDVVR
Mflv_4988|M.gilvum_PYR-GCK IPVAWEVAAALGAPLDAFIVRKLGAPGHDEFAMGALASGGRVVVNDDVVR
Mvan_5893|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2056c|M.bovis_AF2122/97 GLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLAT
Rv2030c|M.tuberculosis_H37Rv GLRITPQQLRDIAEREGRELLRRESAYRGERPPTDITGKTVIVVDDGLAT
MMAR_3483|M.marinum_M GLRITPQQLRDTAEREARELVRREAAYRAGRPPLDVAGKTVVLVDDGLAT
Mflv_4988|M.gilvum_PYR-GCK ALRVSPQQPRDVAEREGRELLRREAAYRAGRPPLELAGKTVIVVDDGLAT
Mvan_5893|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2056c|M.bovis_AF2122/97 GASMFAAVQALRDAQPAQIVIAVPAAPESTCREFAGLVDDVVCATMPTPF
Rv2030c|M.tuberculosis_H37Rv GASMFAAVQALRDAQPAQIVIAVPAAPESTCREFAGLVDDVVCATMPTPF
MMAR_3483|M.marinum_M GASMFAAVQAIRDAEPAHIVIAVPAAPESSCREFAGLVDDVVCASMPTPF
Mflv_4988|M.gilvum_PYR-GCK GSSMFAAVQALQEMDPAEVVIAVPAAPESTCREFAAIVDDVVCASMPTPF
Mvan_5893|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb2056c|M.bovis_AF2122/97 LAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRP-AASTAADVLRRVAID
Rv2030c|M.tuberculosis_H37Rv LAVGESFWDFRQVTDEEVRRLLATPTAGPSLRRP-AASTAADVLRRVAID
MMAR_3483|M.marinum_M LAVGESFWDFRQVTDEEVRNLLATPTTGIPALRP-AVPTPAEVIRNVAID
Mflv_4988|M.gilvum_PYR-GCK LAVGESFWDFRQVTDDEVRELLETPTVGFATARIRLAETPAEVIDRCAVD
Mvan_5893|M.vanbaalenii_PYR-1 ----------------------------------------MDLSRIHALG
:: *:.
Mb2056c|M.bovis_AF2122/97 APGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGF
Rv2030c|M.tuberculosis_H37Rv APGGVPTHEVLAELVGDARIVLIGESSHGTHEFYQARAAMTQWLIEEKGF
MMAR_3483|M.marinum_M AHGGVPPREALEAVIGDARIVLIGESSHGTHEFYEARAEITKWLIEQKGF
Mflv_4988|M.gilvum_PYR-GCK APAGVPPLEALDELIGDARIVLIGESSHGTEEFYAARAEITKWLIEEKGF
Mvan_5893|M.vanbaalenii_PYR-1 DRD--RTLAALLDIVGDSHVVAIGEGAHFVAEYWQCRRHLVELLHRHAGF
. .* ::**:::* ***.:* . *:: .* :.: * .. **
Mb2056c|M.bovis_AF2122/97 GAVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNTVVRD
Rv2030c|M.tuberculosis_H37Rv GAVAAEADWPDAYRVNRYVRGLGEDTNADEALSGFERFPAWMWRNTVVRD
MMAR_3483|M.marinum_M CAVAAEADWPDAYRVNRYVHGLGEDQSAEQALRGFERFPAWMWRNTVVRD
Mflv_4988|M.gilvum_PYR-GCK CGVAAEADWPDAYRVNRYVRGQAGDGSAEEALRGFERFPAWMWRNTVVRD
Mvan_5893|M.vanbaalenii_PYR-1 QLVAMEFGVGEALQLTSWLSGDAGD-DGDADLSSIS-PAAVEWG---AGD
** * . :* ::. :: * . * ..: * .:. .* * . *
Mb2056c|M.bovis_AF2122/97 FVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAA
Rv2030c|M.tuberculosis_H37Rv FVEWLRTRNQRYESGALRQAGFYGLDLYSLHRSIQEVISYLDKVDPRAAA
MMAR_3483|M.marinum_M FVDWLRERNQRCASNGQRQAGFYGLDLYSLHRSMQEVVAFLDRVDPAAAA
Mflv_4988|M.gilvum_PYR-GCK FVAWLRACNADRRAQGRREAGFYGLDLYSLHRSMQEVIDFLDRVDPDAAQ
Mvan_5893|M.vanbaalenii_PYR-1 TMVWLRHFNAAAAARGVPPLRFAGIDLPSAGGAFTPALTPLETYLHDCDP
: *** * : . * *:** * :: .: *: .
Mb2056c|M.bovis_AF2122/97 RARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRNALAY
Rv2030c|M.tuberculosis_H37Rv RARARYACFDHACADDGQAYGFAAAFGAGPSCEREAVEQLVDVQRNALAY
MMAR_3483|M.marinum_M RARARYACFDHTAADDGQAYGYAAAFGAGPSCERQAIEQLVDTQRNALDY
Mflv_4988|M.gilvum_PYR-GCK RARERYSCFDHSSGDDGQAYGFAAAFGAGLSCEHQAVEQLVEMHRSAVEY
Mvan_5893|M.vanbaalenii_PYR-1 ELASTLDDVRAITGVVEGGSGVSAARRWSELDQSTRDAAIAGLARIVLRM
. . . . * :** . : :. * .:
Mb2056c|M.bovis_AF2122/97 ARQDGLLAEDELFYAQQNAQTVRDAEVYYRAMFSGRVTSWNLRDQHMAQT
Rv2030c|M.tuberculosis_H37Rv ARQDGLLAEDELFYAQQNAQTVRDAEVYYRAMFSGRVTSWNLRDQHMAQT
MMAR_3483|M.marinum_M ARRDGLIAEDEAFYAQQNAQTVRNAEVYYRAMFSGRVTSWNLRDQHMAET
Mflv_4988|M.gilvum_PYR-GCK ARRDGLLAEDELFYAQQNAQTVRDAEVYYRSMFGGRVTSWNLRDRHMAET
Mvan_5893|M.vanbaalenii_PYR-1 TALRQRYETRDAGRDHRTALLLGHSALATAYMLQATAEAVAGDGMPLDSS
: : ::.* : .: : *: . . : . : .:
Mb2056c|M.bovis_AF2122/97 LGS--LLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQIV
Rv2030c|M.tuberculosis_H37Rv LGS--LLTHLDRHLDAPPARIVVWAHNSHVGDARATEVWADGQLTLGQIV
MMAR_3483|M.marinum_M LAA--LQAHLDRHREAAPARIVVWAHNSHVGDARATEVWADGQLTLGQLV
Mflv_4988|M.gilvum_PYR-GCK LEA--LLRHLDRQGGSEPARIVVWAHNSHVGDARATEVGADGQLTLGQLA
Mvan_5893|M.vanbaalenii_PYR-1 VRERFLADAVLALRETGDDKVVVLAHNNHVQKTPVVFAGTTYTLPMGSYL
: * : : ::** ***.** .: .. . : *.:*.
Mb2056c|M.bovis_AF2122/97 RERYGDESRSIGFSTYTGTVT-AASEWGGIAQRKAVRPALH---------
Rv2030c|M.tuberculosis_H37Rv RERYGDESRSIGFSTYTGTVT-AASEWGGIAQRKAVRPALHGSVEELFHQ
MMAR_3483|M.marinum_M RQRYGDDSRLIGLCTYSGTVT-AASEWGGIAERKVVRPALHASVEELFHD
Mflv_4988|M.gilvum_PYR-GCK REKFGDHVRLIGYTTYTGTVT-AASEWGGLAERKAVRPALNGSVEELFHE
Mvan_5893|M.vanbaalenii_PYR-1 AGTLGDDYRVIAQTTTDDHVPDMVLDPAGSVGFRVIDAQLPEPAAGTFEH
**. * *. * . *. . : .* . :.: . *
Mb2056c|M.bovis_AF2122/97 ----------AVSRSSSTRLQTVSWCQRG---------------------
Rv2030c|M.tuberculosis_H37Rv T-ADSFLVSARLSRDAEAPLDVVRLGRAIGVVYLPATERQSHYLHVRPAD
MMAR_3483|M.marinum_M TGKDAFLVSAATSPEAADPLSGVRLGRAIGVIYLPATERQSHYFHVRPAD
Mflv_4988|M.gilvum_PYR-GCK VDRPAFLVSPLISHAAAEPLDAVRLGRAIGVIYLPATERQSHYYHVRPSE
Mvan_5893|M.vanbaalenii_PYR-1 A---------LLTAAAAQQPTLTDVRPCPKYAPPQGLRSQSAVVDTDVSA
: : .
Mb2056c|M.bovis_AF2122/97 ------------------------------------
Rv2030c|M.tuberculosis_H37Rv QFDAMIHIDQTRALEPLEVTSRWIAGENPETYPTGL
MMAR_3483|M.marinum_M QFDAMIHIDKTRALEPLETTSLWIAGETPETYPSGL
Mflv_4988|M.gilvum_PYR-GCK QFDGIIHIDRTTALEPLEVTSTWAAGETPETYPTGL
Mvan_5893|M.vanbaalenii_PYR-1 AFDAVVNHPRVTRQPDVHF-----------------