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VLQGRFVGELPELAVPWKAEAAPQPQLLVVNEPLAAELGVDADWLRGPDGLGLLTGTVVPSDATPAAQAY AGHQFGGYQPRLGDGRALLMGEFVDSTGRLRDLHLKGSGRTPFARGGDGLAAVGPMLREYVISEAMHALG IPTTRALAVVATGRPVYRDTVLPGAVLARVASSHLRVGTFQYAAAVSAREGNVDLLRRLADHAIARHHPA AAVAENRYLALLDAVSAAQAKLVAQWMLVGFVHGVMNTDNMTISGETIDYGPCAFMEAFDPATVFSSIDS SGRYAYGNQPAITLWNLARFAETLLPLIHENSGAAIALAEASLDSFAGLYETAWTDGMRAKLGVPGAPAE SVTPLIEQLLPQMQQSHVDYTLFYRLLAGAARGDAEPVRGEFIDLAAFDEWLGRWRALEPDPAVMDRVNP VYIPRNHLVEDALTAATGGDLGPLQQLLTAVTAPFEERPGSERFAEPGEKEFSASFQTFCGT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5772 | - | - | 100% (482) | hypothetical protein Mvan_5772 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1059 | - | 0.0 | 78.17% (481) | hypothetical protein Mflv_1059 |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_1573 | - | 1e-180 | 65.15% (482) | hypothetical protein MMAR_1573 |
| M. avium 104 | MAV_3983 | - | 0.0 | 71.19% (486) | hypothetical protein MAV_3983 |
| M. smegmatis MC2 155 | MSMEG_2445 | - | 0.0 | 67.43% (482) | hypothetical protein MSMEG_2445 |
| M. thermoresistible (build 8) | TH_1211 | - | 0.0 | 70.69% (481) | conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_3460 | - | 1e-176 | 64.11% (482) | hypothetical protein MUL_3460 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5772|M.vanbaalenii_PYR-1 ---------MLQGRFVGELPELAVPWKAEAAPQPQLLVVNEPLAAELGVD
Mflv_1059|M.gilvum_PYR-GCK ------MSIALGSRFAGELSELTVPWKAEEAPQPRLLVLNEPLATELGLD
MSMEG_2445|M.smegmatis_MC2_155 MSVTSDAAVTLHSRFARELPELAIGWQAEPAPAPRLLVLNDALATELGLD
TH_1211|M.thermoresistible__bu VSAAPAEAVTLDNRFARELPELAVAWQAESAPDPKLLVVNEALARELGLD
MMAR_1573|M.marinum_M MSAAPDLTIALQSHFLRDLPELAVRWQAEVPPDARLLVLNEPLAGELKLD
MUL_3460|M.ulcerans_Agy99 MSAAPDLTIALQSHFLRDLPELAVRWQAEVPPDARLLVLNEPLAGELKLD
MAV_3983|M.avium_104 MSVAPETTVALQDRFFRELPELAVRWQAETFPELRLLALNEPLATQLGLD
* .:* :*.**:: *:** * :**.:*:.** :* :*
Mvan_5772|M.vanbaalenii_PYR-1 ADWLRGPDGLGLLTGTVVPSDATPAAQAYAGHQFGGYQPRLGDGRALLMG
Mflv_1059|M.gilvum_PYR-GCK PDWLRGPDGLGLLTGTRVPAEASPVAQAYAGHQFGGFQPRLGDGRALLLG
MSMEG_2445|M.smegmatis_MC2_155 ADWLRSPDGIGLLLGTDVPEGATPVAQAYAGHQFGGYVPRLGDGRALLLG
TH_1211|M.thermoresistible__bu PDWLRSPDGVRFLIGTSLPPGATPVAQAYAGHQFGGLVPRLGDGRALLLG
MMAR_1573|M.marinum_M STWLRSSEGVRFLVGSLLPSGAVPVAQAYAGHQFGGFVPRLGDGRALLLG
MUL_3460|M.ulcerans_Agy99 STWLRSSEGVRFLVGSLLPSGAVPVAQAYAGHQFGGFVPRLGDGRALLLG
MAV_3983|M.avium_104 TGWLRGPDGLRFLTGNLVPTGAAPVAQAYAGHQFGGFVPRLGDGRALLLG
. ***..:*: :* *. :* * *.*********** **********:*
Mvan_5772|M.vanbaalenii_PYR-1 EFVDSTGRLRDLHLKGSGRTPFARGGDGLAAVGPMLREYVISEAMHALGI
Mflv_1059|M.gilvum_PYR-GCK EIEGPDGHLHDLHLKGSGRTPFARGGDGLAAVGPMLREYVISEAMHALGI
MSMEG_2445|M.smegmatis_MC2_155 ELTDVHGRTRDLHLKGSGRTPFARGGDGLAVVGPMLREYIVSEAMHALGI
TH_1211|M.thermoresistible__bu ELVDEQGRLRDLHLKGSGATPFARGGDGLAAVGPMLREYLVSEAMHALGV
MMAR_1573|M.marinum_M EIADTDGRLYDIHLKGSGRTPFARGGDGLAVVGPMLREYIVSEAMHALGI
MUL_3460|M.ulcerans_Agy99 EIADTDGRLYDIHLKGSGRTPFARGGDGLAVVGPMLREYIVSEAMHALGI
MAV_3983|M.avium_104 ELVDDEGRLRDIHLKGSGATPFARGGDGLAAVGPMLREYVVSEAMHALGV
*: . *: *:****** ***********.********::********:
Mvan_5772|M.vanbaalenii_PYR-1 PTTRALAVVATGRPVYRDTVLPGAVLARVASSHLRVGTFQYAAAVSAREG
Mflv_1059|M.gilvum_PYR-GCK PTTRALAVVATGKTVYRESPLPGAVLARVASSHLRVGTFQFAPLLMRASG
MSMEG_2445|M.smegmatis_MC2_155 PTTRSLAVVATGRDVWRETKQPGAVLARVASSHLRVGSFQYAYQYATAAK
TH_1211|M.thermoresistible__bu PTTRSLSVVATGRPVYRETELPGAVLARVASSHLRVGSFQYAALVG----
MMAR_1573|M.marinum_M PTTRSLAVVGTGRQVQRETPLPGALLVRVARSHLRVGSFQYAAATG----
MUL_3460|M.ulcerans_Agy99 PTTRSLAVVGTGRQVQRETPLPGALLVRVARSHLRVGSFQYAAATG----
MAV_3983|M.avium_104 PTTRSLAVVGTGRPVYREATLPGAVLARVAGSHLRVGSFQYAAATG----
****:*:**.**: * *:: ***:*.*** ******:**:*
Mvan_5772|M.vanbaalenii_PYR-1 NVDLLRRLADHAIARHHPAAAVAENRYLALLDAVSAAQAKLVAQWMLVGF
Mflv_1059|M.gilvum_PYR-GCK NTDLLRRLADHAIARHHPAAADAEQPYLALLEAVSAAQARLVAQWMSVGF
MSMEG_2445|M.smegmatis_MC2_155 DDEVLRRLADHAISRHHPQAAEADNPYLALFEAVVSAQASLLAQWMLVGF
TH_1211|M.thermoresistible__bu DEALVRRLADHAIARHHPAAADAANPYLGLFEAVISVQARLVARWMLVGF
MMAR_1573|M.marinum_M DVELLRRLADYAIARHYPGAADAERPYLALFEEVVAVQAALLARWMLIGF
MUL_3460|M.ulcerans_Agy99 DVELLRRLADYAIAHHYPGAADAERPYLALFEEVVAVQAALLARWMLIGF
MAV_3983|M.avium_104 NRDLLRRLADHAIARHHPGAADAEQPYLALFEAVVAAQASLIAQWMLIGF
: ::*****:**::*:* ** * . **.*:: * :.** *:*:** :**
Mvan_5772|M.vanbaalenii_PYR-1 VHGVMNTDNMTISGETIDYGPCAFMEAFDPATVFSSIDSSGRYAYGNQPA
Mflv_1059|M.gilvum_PYR-GCK IHGVMNTDNMTISGETIDYGPCAFMEAFDPATVFSSIDSWGRYAYGNQPS
MSMEG_2445|M.smegmatis_MC2_155 IHGVMNTDNMTIAGETIDYGPCAFMDTFDPATVFSSIDHGGRYAYGNQPA
TH_1211|M.thermoresistible__bu VHGVMNTDNTTISGETIDYGPCAFLDVYDPATVFSSIDDRGRYAYGNQPA
MMAR_1573|M.marinum_M VHGVMNTDNMTISGETIDYGPCAFMEAYDPETVFSSIDHWGRYAYANQPV
MUL_3460|M.ulcerans_Agy99 VHGVMNTDNMTISGETIDYEPCAFMEAYDPETVFSSIDHWGRYAYANQPV
MAV_3983|M.avium_104 VHGVMNTDNMTISGETIDYGPCAFMEAYDPDTVFSSIDFWGRYAYGNQPV
:******** **:****** ****::.:** ******* *****.***
Mvan_5772|M.vanbaalenii_PYR-1 ITLWNLARFAETLLPLIHENSGAAIALAEASLDSFAGLYETAWTDGMRAK
Mflv_1059|M.gilvum_PYR-GCK IALWNLARFAEALLPLLADDAEAGIAVAEASLGEFQGLYEAAWTDAMARK
MSMEG_2445|M.smegmatis_MC2_155 VAHWNLARFAETLLPLIAEDVDTAVDLVTAALGQFPQQFDTAWSTGMRTK
TH_1211|M.thermoresistible__bu IAGWNLARFAEALLPLLADDTDRAIAVATQALQGFPGQYEAAWTAGMRTK
MMAR_1573|M.marinum_M VAGWNLARFAEALLPLLADDMQEGIALAEKSFGVFRTRYDAVWCSGMRAK
MUL_3460|M.ulcerans_Agy99 VAGWNLARFAEAPLPLLADDMQEGIALAEKSFGVFRTRYDAVWCSGMRAK
MAV_3983|M.avium_104 IAGWNLARFAETLLPLFSENTEEAIALAERSFGVFQTRYDAVWAAGMRAK
:: ********: ***: :: .: :. :: * :::.* .* *
Mvan_5772|M.vanbaalenii_PYR-1 LGVPG-APAESVTPLIEQLLPQMQQSHVDYTLFYRLLAGAARGD----AE
Mflv_1059|M.gilvum_PYR-GCK LGVAG-ASADTVEALVGDLLTQLQQSGLDWTLFFRRLAGAARGD----AE
MSMEG_2445|M.smegmatis_MC2_155 LGLSARVDHTTATALVNDLLVLLQQTRTDYTSAFRDLGRVARG-----AQ
TH_1211|M.thermoresistible__bu LGFRANADIP--KELIDDLLAQLIQSHIDYTSFFRTLSRAARGD----TE
MMAR_1573|M.marinum_M LGLPAVTEAEVVKPLADELLQLLQQGQVDYTSFFRHLAAAARGD----GG
MUL_3460|M.ulcerans_Agy99 LGLPAVTEAEVVKPLADELLQLLRQGQVDYTSFFRHLAAAARGD----GG
MAV_3983|M.avium_104 LGLPAQVDAEFAAALIDELLALLKANHVDYTSFFRQLGRAARGDDRSAAE
**. . . * :** : *:* :* *. .***
Mvan_5772|M.vanbaalenii_PYR-1 PVRGEFIDLAAFDEWLGRWRALEPDPAVMDRVNPVYIPRNHLVEDALTAA
Mflv_1059|M.gilvum_PYR-GCK PVRGEFIDLATFDGWLQRWRDLGPDADAMDRVNPVYIPRNHLVEEALTAA
MSMEG_2445|M.smegmatis_MC2_155 PS------LPFTDEWLSRWRACDPDPDVMDRVNPVYIPRNHLVEDALTAA
TH_1211|M.thermoresistible__bu PARGVFLDLAEFDRWLSRWRDLDPDPELMDRSNPVYIPRNHLVEQALSAA
MMAR_1573|M.marinum_M AARAMFDAPSGFDDWLSRWQNLGPDAELMDGVNPIYIPRNHLVEEALTAA
MUL_3460|M.ulcerans_Agy99 AARAMFDAPSGFDDWLSRWQNLGPDAELMDGVNPIYIPRNHLVEEALTAA
MAV_3983|M.avium_104 PAREMFMDLPGFDAWLARWRALGPDADAMDRVNPIYIPRNHLVEEALAAA
. . * ** **: **. ** **:*********:**:**
Mvan_5772|M.vanbaalenii_PYR-1 TGGDLGPLQQLLTAVTAPFEERPGSERFAEPGEKEFSASFQTFCGT
Mflv_1059|M.gilvum_PYR-GCK TGGDLGPVEKLLDAIRSPFDVRAGLDRYAEPGPREFSASFQTFCGT
MSMEG_2445|M.smegmatis_MC2_155 TTGDLAPLATLMTALKTPFTERAGFEAHAAPAPEDFGP-YRTFCGT
TH_1211|M.thermoresistible__bu VDGDMEPFRRLLTVVTDPFTERPGLERYTEPAPESFGP-YQTFCGT
MMAR_1573|M.marinum_M TDGNLDPFRRLLDAVTDPYVERPGLERYAGPAPEDFGA-YRTYCGT
MUL_3460|M.ulcerans_Agy99 TDGNLDPFRRLLDAVTDPYVERPGLEHYAGPAPEDFGA-YRTYCGT
MAV_3983|M.avium_104 TDGDLDPLDQLLAAVTAPYTERPGFERYASPAPEDFGK-YQTFCGT
. *:: *. *: .: *: *.* : .: *. ..*. ::*:***