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VRWRIRAGTAAATAALALVAGVPVVQADPVPMRPQVYDKVSRDGWHLNIRIENEVVNSIPNLANAQNSRE GFVTASATATAVGGANPITDSIFILGYQLGCQSDVSAGLQYGGTAGLGPVGSLGLGGGILPSAAVGVNGG AAGFVQTVLQPGVIVDLPLSNMTLGPSGQAMLDIDNIHIKADACGGDVTIRSYAYLRVSTEAAHTQFAIY GDPIKI
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5768 | - | - | 100% (216) | hypothetical protein Mvan_5768 |
| M. vanbaalenii PYR-1 | Mvan_4117 | - | 9e-17 | 31.03% (232) | hypothetical protein Mvan_4117 |
| M. vanbaalenii PYR-1 | Mvan_5016 | - | 5e-14 | 28.65% (171) | hypothetical protein Mvan_5016 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2667c | PE_PGRS46 | 5e-05 | 56.76% (37) | PE-PGRS family protein |
| M. gilvum PYR-GCK | Mflv_1735 | - | 4e-15 | 29.48% (173) | hypothetical protein Mflv_1735 |
| M. tuberculosis H37Rv | Rv2634c | PE_PGRS46 | 5e-05 | 56.76% (37) | PE-PGRS family protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2329c | - | 4e-74 | 65.28% (216) | hypothetical protein MAB_2329c |
| M. marinum M | MMAR_1541 | - | 1e-09 | 27.75% (173) | hypothetical protein MMAR_1541 |
| M. avium 104 | MAV_3943 | - | 1e-15 | 29.57% (230) | hypothetical protein MAV_3943 |
| M. smegmatis MC2 155 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_4651 | - | 3e-13 | 30.22% (182) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2391 | - | 4e-09 | 27.17% (173) | hypothetical protein MUL_2391 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5768|M.vanbaalenii_PYR-1 -----------------MRWRIRAGTAAATAALALVAGVPVVQADPVPMR
MAB_2329c|M.abscessus_ATCC_199 -----------------MAVRKRVGAVMALVTAICTFATAPAHADPVAMA
MMAR_1541|M.marinum_M -------------MPISAVIRRAAVLAVCLVVSIS-APSAGAQPDAQPPP
MUL_2391|M.ulcerans_Agy99 ------------MMPISAVIRRAAVLAVCLVVSIS-APSAGAQPDAQPPP
MAV_3943|M.avium_104 -----------------MVVRRALVAAVCLALSLPTAPTTGADPDAAPPP
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------MRVAATTAVAVLGLAGATSASAQPDPVSPV
Mb2667c|M.bovis_AF2122/97 MSFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAA
Rv2634c|M.tuberculosis_H37Rv MSFVIAVPEALTMAASDLANIGSTINAANAAAALPTTGVVAAAADEVSAA
Mvan_5768|M.vanbaalenii_PYR-1 P----------------------QVYDKVSRDGWHLNIRIENEVVNSIPN
MAB_2329c|M.abscessus_ATCC_199 P----------------------QTYTKVTRDGWTLVIRIDHETINSVPN
MMAR_1541|M.marinum_M ----------GAVPPDDGAVPPGTPAKITTPDGWVLALGAKDEKHVPVAP
MUL_2391|M.ulcerans_Agy99 ----------GAVPPDDGAVPPGTPAKITTPDGWVLALGAKDEKHVPVAP
MAV_3943|M.avium_104 P---------EAAPAAEGALPSNPPAILKTPDGWTLGLGARDEQQVPVAP
TH_4651|M.thermoresistible__bu ----------------------------------VLTVWAKDETQIPIQP
Mflv_1735|M.gilvum_PYR-GCK APGVQAVADVGPPPAPDGAVASGPPGFVVTPDGWELTVSAKDEFQVAVAP
Mb2667c|M.bovis_AF2122/97 VAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQD
Rv2634c|M.tuberculosis_H37Rv VAALFGSYAQSYQAFGAQLSAFHAQFVQSLTNGARSYVVAEATSAAPLQD
: .:
Mvan_5768|M.vanbaalenii_PYR-1 LANAQNS-------REGFVTASATATAVGG---------ANPITDSIFIL
MAB_2329c|M.abscessus_ATCC_199 LAEASNS-------REAFVTFDATAVATGG---------SAPITDSLFIA
MMAR_1541|M.marinum_M MTTAISS-------REYLSSGIFGASLTGP-----------ETPRGILEV
MUL_2391|M.ulcerans_Agy99 MTTAISS-------REYLSSGIFGASLTGP-----------ETPRGILEV
MAV_3943|M.avium_104 LTTALSS-------REYLASGIFVGSLSGP-----------TQPQGVLEV
TH_4651|M.thermoresistible__bu LTTALSS-------REYEVGATFVGSITGPEG-------SDETPEGVLEV
Mflv_1735|M.gilvum_PYR-GCK LTTALSS-------REYLVAGTFEGAVAGAG--------TAPTSGGTLEV
Mb2667c|M.bovis_AF2122/97 LLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAP
Rv2634c|M.tuberculosis_H37Rv LLGVVNAPAQALLGRPLIGNGANGADGTGAPGGPGGLLLGNGGNGGSGAP
: . .: * . * .
Mvan_5768|M.vanbaalenii_PYR-1 GYQLGC--QSDVSAGLQYGGTAGLGPVG-----SLGLGGGILPS-AAVGV
MAB_2329c|M.abscessus_ATCC_199 GYQLGC--QTDVSSGLQIGGTGGL--AG-----SVGYSGG-----PSVGG
MMAR_1541|M.marinum_M GYEIGCGIDMSTSNGFVMANSGGVAPS---IGAELPLGPGQPPI-LIPLI
MUL_2391|M.ulcerans_Agy99 GYEIGCGIDMSTSNGFVMANSGGVAPS---IGAELPLGPGQPPI-LIPLI
MAV_3943|M.avium_104 GYEIGCGIDMSTSDGVTIGGTAGITPG---VTGPVTGVPGD----VLPLV
TH_4651|M.thermoresistible__bu GYEIGCGIDMSTSQGVSLSGSAGLNPSLGLIATDIVAPDGLPIFGANAGI
Mflv_1735|M.gilvum_PYR-GCK GYQIGCGISLNVVK---LNGSAGFTPS---INDQRRLG-----------V
Mb2667c|M.bovis_AF2122/97 GQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGG
Rv2634c|M.tuberculosis_H37Rv GQPGGAGGDAGLIGNGGTGGKGGDGLVGSGAAGGVGGRGGWLLGNGGTGG
* *. . . ...*
Mvan_5768|M.vanbaalenii_PYR-1 NGGAAGFVQTVLQPGVIVDLPLSNMTLGPSGQAMLDIDNIHIKADACGGD
MAB_2329c|M.abscessus_ATCC_199 SGGLAGFVQTILQPGVITDLPLANMALSDGGKAMLDVDNLHIKADACGGD
MMAR_1541|M.marinum_M TGQYNNVVSVGLKPGFVVVVPVVRKEFK-GANPWIMISAFHLKIDGCVGQ
MUL_2391|M.ulcerans_Agy99 TGQYNNVVSVGLKPGFVVVVPVVRKEFK-GANPWIMISAFYLKIDGCVGQ
MAV_3943|M.avium_104 VAPIAGVLNVGLKPGLVIVVPVVKKQFR-GPNPWVMVSNFHVKIDGCVGQ
TH_4651|M.thermoresistible__bu GPSLGGAVTVGLKPGFVNIVPVSKKPFK-GADPWVMVKGFRVKIDGCVGE
Mflv_1735|M.gilvum_PYR-GCK AFPVSAQIEVFPQPGEVTTVQLTQKTFE-GSNPRVTVKDVHIKVDGCVGE
Mb2667c|M.bovis_AF2122/97 AGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGV
Rv2634c|M.tuberculosis_H37Rv AGGAAGATLVGGTGGVGGATGLIGSGGFGGAGGAAAGVGTTGGVGGSGGV
. * : . ... *
Mvan_5768|M.vanbaalenii_PYR-1 VTIRSYAYLR-----VSTEAAHTQFAIYGDPIKI----------------
MAB_2329c|M.abscessus_ATCC_199 VTIRSYVYLR-----ISTASAHTEFAIYGDPMKI----------------
MMAR_1541|M.marinum_M SFVRSYATLT-----RITDESDVVLSYVGSTKAV----------------
MUL_2391|M.ulcerans_Agy99 SFVRSYATLT-----QITDESDVVLSYVGSTKAV----------------
MAV_3943|M.avium_104 SFIRSYAVLN-----RVTDESDVVLSYVGVTKAV----------------
TH_4651|M.thermoresistible__bu SFIRSYAYLT-----RATDQSEAVLAWYGVTKKI----------------
Mflv_1735|M.gilvum_PYR-GCK SFLRSYAVLT-----SSTDAADDIVAYYGVTKAV----------------
Mb2667c|M.bovis_AF2122/97 GGVFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGP
Rv2634c|M.tuberculosis_H37Rv GGVFGNGGFGGAGGLGAAGGVGGAASYFGTGGGGGVGGDGAPGGDGGAGP
: . : : : *
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 LLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPG
Rv2634c|M.tuberculosis_H37Rv LLIGNGGVGGLGGAGAAGGNGGAGGMLLGDGGAGGQGGPAVAGVLGGMPG
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 AGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGN
Rv2634c|M.tuberculosis_H37Rv AGGNGGNANWFGSGGAGGQGGTGLAGTNGVNPGSIANPNTGANGTDNSGN
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 GNQTGGNGGPGPAGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGT
Rv2634c|M.tuberculosis_H37Rv GNQTGGNGGPGPAGGVGEAGGVGGQGGLGESLDGNDGTGGKGGAGGTAGT
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 DGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGGAGGKGGQ
Rv2634c|M.tuberculosis_H37Rv DGGAGGAGGAGGIGETDGSAGGVATGGEGGDGATGGVDGGVGGAGGKGGQ
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 GHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNG
Rv2634c|M.tuberculosis_H37Rv GHNTGVGDAFGGDGGIGGDGNGALGAAGGNGGTGGAGGNGGRGGMLIGNG
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 GAGGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGG
Rv2634c|M.tuberculosis_H37Rv GAGGAGGTGGTGGGGAAGFAGGVGGAGGEGLTDGAGTAEGGTGGLGGLGG
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 VGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGN
Rv2634c|M.tuberculosis_H37Rv VGGTGGMGGSGGVGGNGGAAGSLIGLGGGGGAGGVGGTGGIGGIGGAGGN
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 GGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGL
Rv2634c|M.tuberculosis_H37Rv GGAGGAGTTTGGGATIGGGGGTGGVGGAGGTGGTGGAGGTTGGSGGAGGL
Mvan_5768|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2329c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_1541|M.marinum_M --------------------------------------------------
MUL_2391|M.ulcerans_Agy99 --------------------------------------------------
MAV_3943|M.avium_104 --------------------------------------------------
TH_4651|M.thermoresistible__bu --------------------------------------------------
Mflv_1735|M.gilvum_PYR-GCK --------------------------------------------------
Mb2667c|M.bovis_AF2122/97 IGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGG
Rv2634c|M.tuberculosis_H37Rv IGWAGAAGGTGAGGTGGQGGLGGQGGNGGNGGTGATGGQGGDFALGGNGG
Mvan_5768|M.vanbaalenii_PYR-1 ----------------------------
MAB_2329c|M.abscessus_ATCC_199 ----------------------------
MMAR_1541|M.marinum_M ----------------------------
MUL_2391|M.ulcerans_Agy99 ----------------------------
MAV_3943|M.avium_104 ----------------------------
TH_4651|M.thermoresistible__bu ----------------------------
Mflv_1735|M.gilvum_PYR-GCK ----------------------------
Mb2667c|M.bovis_AF2122/97 AGGAGGSPGGSSGIQGNMGPPGTQGADG
Rv2634c|M.tuberculosis_H37Rv AGGAGGSPGGSSGIQGNMGPPGTQGADG