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PEPSRTDVRALRARLDDLTISDAARLGRRLRQLRDPSEEQLGKLAKQFDTAEALVASRLAAVPQISYPDL PVTERRDEIAAAIAANQVVIVAGETGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAARIAEELG TPLGEAVGYTVRFTDQASDRTLVKLMTDGILLAEVQRDRRLLRYDTLIIDEAHERSLNIDFLLGYLRQLL PRRPDLKVIVTSATIEPERFAAHFAGAPIVEVSGRTYPVEIRYRPLEVTVPGQDGEDPDDPDHEVVRTEL RDPTEAIIDAVAELEAEPPGDVLVFLSGEREIRDTAEALRAVVDPGHTEVLPLYARLPTAEQQKVFHPGR TARRIVLATNVAETSLTVPGIRYVVDPGTARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCI RLYSEQDFEARPRYTDPEILRTNLAAVILQMAALGFGDIEGFGFLDPPDARSIRDGVALLQELGAFDQQA DLTDIGRRLAQIPVDPRLGRMILQADAEGCVREMLVLAAALSIPDPRERPADKEEAARQKHARFADQHSD FTSYLNLWHYLTEQRKERSGSSFRRMCRDEFLHYLRIREWQDLVGQLRGICRDIGIREQDEPADPAAVHA ALAAGLLSHVGMRDTDGRSYQGARNAKFVLAPGSVLSKRPPRWVVVADLVETSRLFGRTAARIEPETVER VAGHLVQRTYSEPHWDAERGAVMAYERVTLYGLPLVARRRVGYAQVDPEAARDLFIRHALVEGDWQTKHH FFRDNARLREELAELEDRARRRDLLVGDDEVFAFYDARVPADVVSARHFDGWWRKQRHRTPGLLTMTRDD LLRNEAGAEQPDAWQAGDLSLPLSYRYDPGSADDGVTVHVPVDVLARLGGDEFAWQVPALREELLTALIK SLPKDLRRNFVPAPDTARALLASITPDSGPLLDAIQRELRRRTGILVPIDAFDLDKLPPHLRVTFAVEAA DGTVVSRGKDLGELQQQLAAPSRQAVAATVAGDLERTGLRDWPPELDELPRVVERKGATGHLVRGYPALV DAGKAADIKVFATKAEQDAAMGPGCRRLLLTAGPSVTKGVERSLDTRTRLVLGTNPDGSLAALIDDCAAA AVQVLVPAPAWTREEFAAARKRLAANIVATTADVVRRVEKVLVALHEVEVALPSKPTPAQADAIADIRGQ LARLVPPGFVAATGAARLGDLARYLTAIGRRLERLPHAPAADRERMERVAAVQAEYDDLRRALSPGRAAA TDVQDIARMIEELRVSLWAQQLGTARPVSEQRIYRAIDAVGVAGPGGGR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_5766 | - | - | 100% (1310) | ATP-dependent helicase HrpA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_1063 | - | 0.0 | 86.89% (1312) | ATP-dependent helicase HrpA |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0056c | - | 0.0 | 75.63% (1305) | ATP-dependent helicase HrpA |
M. marinum M | MMAR_2947 | - | 0.0 | 74.58% (1306) | HrpA-like helicase |
M. avium 104 | MAV_2737 | hrpA | 0.0 | 75.08% (1292) | ATP-dependent helicase HrpA |
M. smegmatis MC2 155 | MSMEG_6587 | hrpA | 0.0 | 77.64% (1315) | ATP-dependent helicase HrpA |
M. thermoresistible (build 8) | TH_0802 | hrpA | 0.0 | 76.77% (1317) | ATP-dependent helicase HrpA |
M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment MAB_0056c|M.abscessus_ATCC_199 ------MSELS-RTELRARLDGVTFRDASRLGRRLKNQR-DTNPDALTKL MSMEG_6587|M.smegmatis_MC2_155 ------MSERQELRELRARLDGLTIRDAARLGRRLKNLRGDDLTKNFAKI Mvan_5766|M.vanbaalenii_PYR-1 ----MPEPSRTDVRALRARLDDLTISDAARLGRRLRQLR-DPSEEQLGKL Mflv_1063|M.gilvum_PYR-GCK ----MPEQPSTDVRALRARLDGLTISDAARLGRRLRQQR-TPDPAALARL TH_0802|M.thermoresistible__bu -----VSDPSHDVRALRARLDGLTHRDAARLGRRLRQVR-GAKPEQLQRI MMAR_2947|M.marinum_M -------MADLSVAQLRSRLDGLSTRDAVRLGRRLKGLR-GAKPERLQQL MAV_2737|M.avium_104 MAAVAEPSFPVSGAQLRGRLDGLTIRDAARLGRRLKKLR-GAAPDKLRQL **.***.:: ** ******: * : :: MAB_0056c|M.abscessus_ATCC_199 AE----QITAAEALIATRAAAVPVITYPDLPVSAHREELAHAISAHQVVV MSMEG_6587|M.smegmatis_MC2_155 EQ----QIAQAEALVLTRQAAVPQITYPDLPVTQRRDDLAKAIAENQVVV Mvan_5766|M.vanbaalenii_PYR-1 AK----QFDTAEALVASRLAAVPQISYPDLPVTERRDEIAAAIAANQVVI Mflv_1063|M.gilvum_PYR-GCK AE----RFTAAEALVATRLAAVPEITYPDLPVSERRDDIAAAIAANQVVI TH_0802|M.thermoresistible__bu AE----QIAAGEALVAARAAAVPEISYPDLPVSERRHEIAEAIANHQVVV MMAR_2947|M.marinum_M TEQIAVQISAAEALIATRQAAVPTITYPDLPVSERRQEIAEAIRANQVVV MAV_2737|M.avium_104 AD----QIAAAEAVVAARHAAVPAVSYPDLPVSERRREIADAIRAHQVVV . :: .**:: :* **** ::******: :* ::* ** :***: MAB_0056c|M.abscessus_ATCC_199 VAGATGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAERIAEELG MSMEG_6587|M.smegmatis_MC2_155 VAGATGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAQRIADELG Mvan_5766|M.vanbaalenii_PYR-1 VAGETGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAARIAEELG Mflv_1063|M.gilvum_PYR-GCK VAGETGSGKTTQLPKICLEMGRGIRGTIGHTQPRRLAARTVATRIAEELG TH_0802|M.thermoresistible__bu VAGETGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAQRIADELG MMAR_2947|M.marinum_M VAGETGSGKTTQLPKICLDIGRGVRGTIGHTQPRRLAARTVAQRIADELQ MAV_2737|M.avium_104 IAGETGSGKTTQLPKVCLEAGRGIRGTIGHTQPRRLAARTVAQRIADELG :** ***********:**: ***:****************** ***:** MAB_0056c|M.abscessus_ATCC_199 TQLGETVGYTVRFTDQASDRTLVKLMTDGILLAEIQRDRRLLRYDTLILD MSMEG_6587|M.smegmatis_MC2_155 TPLGEAVGYTVRFTDQASDSTLVKLMTDGILLAEIQRDRRLLRYDTLILD Mvan_5766|M.vanbaalenii_PYR-1 TPLGEAVGYTVRFTDQASDRTLVKLMTDGILLAEVQRDRRLLRYDTLIID Mflv_1063|M.gilvum_PYR-GCK TPLGEAVGYTVRFTDQASDRTLVKLMTDGILLAEVQRDRRLLRYDTLIID TH_0802|M.thermoresistible__bu TPLGEAVGYTVRFTDQAGDRTLVKLMTDGILLAEIQRDRRLLRYDTIIID MMAR_2947|M.marinum_M TPLGDAVGYAVRFTDQVSERTLVKLMTDGILLAEIQRDRRLLRYDTLILD MAV_2737|M.avium_104 SPLGETVGYTVRFTDQVSDRTLIKLMTDGILLAEIQRDRRLLRYDTLILD : **::***:******..: **:***********:***********:*:* MAB_0056c|M.abscessus_ATCC_199 EAHERSLNIDFLLGYLRELLPRRPDLKIIVTSATIEPQRFSAHFGN---- MSMEG_6587|M.smegmatis_MC2_155 EAHERSLNIDFLLGYLRELLPRRPDLKVIVTSATIEPERFSRHFGD---- Mvan_5766|M.vanbaalenii_PYR-1 EAHERSLNIDFLLGYLRQLLPRRPDLKVIVTSATIEPERFAAHFAG---- Mflv_1063|M.gilvum_PYR-GCK EAHERSLNIDFLLGYLRRLLPRRPDLKVIVTSATIEPERFARFFAGGEHG TH_0802|M.thermoresistible__bu EAHERSLNIDFLLGYLKGLLPRRPDLKVIITSATIEPRRFAKHFDA---- MMAR_2947|M.marinum_M EAHERSLNIDFLLGYLRELLPRRPDLKLIVTSATIEPQRFAAHFGG---- MAV_2737|M.avium_104 EAHERSLNIDFLLGYLRALLPRRPDLKLIITSATIEPRRFSEHFAN---- ****************: *********:*:*******.**: .* MAB_0056c|M.abscessus_ATCC_199 ----APIVEVSGRTYPVEIRYRPLEVPVHGTSGAKAEDEPDDPDHEIVRT MSMEG_6587|M.smegmatis_MC2_155 ----APIVEVSGRTYPVEIRYRPLEVPAPTSD----DEDPDDPDHEIVRT Mvan_5766|M.vanbaalenii_PYR-1 ----APIVEVSGRTYPVEIRYRPLEVTVPGQD----GEDPDDPDHEVVRT Mflv_1063|M.gilvum_PYR-GCK SGAGAPIVEVSGRTYPVEIRHRPLEVAVSAAD----DDDPDDPDHEVVRT TH_0802|M.thermoresistible__bu -----PVVEVSGRTYPVEIRYRPLEVPAGTDT----ADDPDDPDHEIVRT MMAR_2947|M.marinum_M ----APIIEVSGRTYPVAIRYRPLEVPVSTGSPED-SSDPDDPDHEIVRT MAV_2737|M.avium_104 ----APVIEVSGRTYPVEIRYRPLEIALPSATAD----DPDDPDHEIVRT *::********* **:****:. :*******:*** MAB_0056c|M.abscessus_ATCC_199 ELRDQTEAIADAVRELQNEPPGDVLVFLSGEREIRDTSEALRDIVRA-GT MSMEG_6587|M.smegmatis_MC2_155 EVRDPTEAIVDAVRELEAEPPGDVLVFLSGEREIRDTAEALKDLR---NT Mvan_5766|M.vanbaalenii_PYR-1 ELRDPTEAIIDAVAELEAEPPGDVLVFLSGEREIRDTAEALRAVVDPGHT Mflv_1063|M.gilvum_PYR-GCK ELRDPTEAIIDAVAELESEPRGDVLVFLSGEREIRDTAEALRAVTDPGHT TH_0802|M.thermoresistible__bu EIRDQTEAIIDAVRELDAEPPGDVLVFLSGEREIRDTAEALRGTLDP-DV MMAR_2947|M.marinum_M ETRDEVEAIVDAVHELQNEAPGDVLVFLSGEREIRDTAEALSGLE---HT MAV_2737|M.avium_104 ETRDEVEAIVDAIAELEAEPPGDVLVFLSGEREIRDTAEALTGLK---HT * ** .*** **: **: *. ****************:*** . MAB_0056c|M.abscessus_ATCC_199 EVLPLYARLPTAEQHKVFA-SHTGRRVVLATNVAETSLTVPGIRYVIDPG MSMEG_6587|M.smegmatis_MC2_155 EVLPLYARLPTAEQQKVFQPSHAGRRVVLATNVAETSLTVPGIRYVVDPG Mvan_5766|M.vanbaalenii_PYR-1 EVLPLYARLPTAEQQKVFHPGRTARRIVLATNVAETSLTVPGIRYVVDPG Mflv_1063|M.gilvum_PYR-GCK EVLPLYARLPTAEQQKVFSPSRAARRIVLATNVAETSLTVPGIRYVVDPG TH_0802|M.thermoresistible__bu EVLPLYARLPTAEQQKVFTPHRLRRRIVLATNVAETSLTVPGIRYVVDPG MMAR_2947|M.marinum_M EVLPLYARLPTAEQQKVFA-PHTGRRVVLATNVAETSLTVPGIRYVVDPG MAV_2737|M.avium_104 EVLPLYARLPTAEQQKVFA-PHTGRRVVLATNVAETSLTVPGIRYVVDPG **************:*** : **:*******************:*** MAB_0056c|M.abscessus_ATCC_199 TARISRYSRRTKVQRLPIEPISQASAAQRSGRSGRTAPGICIRLYSEQDF MSMEG_6587|M.smegmatis_MC2_155 TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCIRLYSEEDF Mvan_5766|M.vanbaalenii_PYR-1 TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCIRLYSEQDF Mflv_1063|M.gilvum_PYR-GCK TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCIRLYSEQDF TH_0802|M.thermoresistible__bu TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRVAPGVCIRLYSEEDF MMAR_2947|M.marinum_M NARISRYSRRLKVQRLPIEPISQASAAQRAGRCGRVAPGICIRLYSEDDF MAV_2737|M.avium_104 NARISRYSRRLKVQRLPIEPISQASAAQRAGRCGRVAPGVCIRLYSEADF .********* ******************:**.**.***:******* ** MAB_0056c|M.abscessus_ATCC_199 EARPRYTDPEILRTNLAAVILQMAALQLGDIENFPFLDPPDKRSIRDGVQ MSMEG_6587|M.smegmatis_MC2_155 ESRPRYTDPEILRTNLAAVILQMSALGLGDIENFPFLDPPDARSIRDGIQ Mvan_5766|M.vanbaalenii_PYR-1 EARPRYTDPEILRTNLAAVILQMAALGFGDIEGFGFLDPPDARSIRDGVA Mflv_1063|M.gilvum_PYR-GCK ESRPRYTDPEILRTNLAAVILQMAALGFGDIEAFGFLDPPDARSIRDGVA TH_0802|M.thermoresistible__bu ESRPEFTEPEILRTNLAAVILQMAALGFGAVEDFPFLDPPDQRSIRDGVA MMAR_2947|M.marinum_M AARPQYTDPEILRTNLAAVILQMAALQLGEIENFGFLDPPDRRSVRDGVQ MAV_2737|M.avium_104 AARPRYTEPEILRTNLAAVLLQMAALQLGDIENFPFLDPPDRRSVRDGVQ :**.:*:***********:***:** :* :* * ****** **:***: MAB_0056c|M.abscessus_ATCC_199 LLQELGAFS----ADG--------------TITELGRRLARLPLDPRIGR MSMEG_6587|M.smegmatis_MC2_155 LLQELGAFDTSSAAGGGNSASAAGGGNSVPALTETGRRLARLPLDPRIGR Mvan_5766|M.vanbaalenii_PYR-1 LLQELGAFD----QQA--------------DLTDIGRRLAQIPVDPRLGR Mflv_1063|M.gilvum_PYR-GCK LLQELGAFD----RQG--------------ELTDIGRRLAQIPVDPRLGR TH_0802|M.thermoresistible__bu LLRELGAFD----ERG--------------EITDVGRRLAQLPVDPRLGR MMAR_2947|M.marinum_M LLQELGAFD----PTG--------------AITDLGRRLARLPVDPRLGR MAV_2737|M.avium_104 LLTELGAFD----RQG--------------AITERGRRLARLPVDPRLGR ** *****. . :*: *****::*:***:** MAB_0056c|M.abscessus_ATCC_199 MILQADAEGCVEEILVLAAALSIPDPRERPADREEAARQKHARFADDHSD MSMEG_6587|M.smegmatis_MC2_155 MILQADAEGCVREALVLAAALSIPDPRERPSDREEAARQKHARFADEHSD Mvan_5766|M.vanbaalenii_PYR-1 MILQADAEGCVREMLVLAAALSIPDPRERPADKEEAARQKHARFADQHSD Mflv_1063|M.gilvum_PYR-GCK MILQADHEGCVREMLVLAAALSIPDPRERPADREDAARQKHARFADEHSD TH_0802|M.thermoresistible__bu MVLQAETEGCVREVLVLAAALSIPDPRERPLDKEDAARAKHARFADEHSD MMAR_2947|M.marinum_M MILQAGVEGCLREVLVLAAALTIPDPRERPTDREEAARQKHARFADEDSD MAV_2737|M.avium_104 MILAAQTEGCVREMLVLAAALSIPDPRERPSDREEAARQKHARFADEHSD *:* * ***:.* *******:******** *:*:*** *******:.** MAB_0056c|M.abscessus_ATCC_199 FIAYLNLWRYLQDQRSQLSGSAFRRMCRNEFLHYLRIREWQDLVGQLRSI MSMEG_6587|M.smegmatis_MC2_155 FISYLNLWNYLREQRNELSGNAFRRMCRDEFLHYLRIREWQDLVGQLRSI Mvan_5766|M.vanbaalenii_PYR-1 FTSYLNLWHYLTEQRKERSGSSFRRMCRDEFLHYLRIREWQDLVGQLRGI Mflv_1063|M.gilvum_PYR-GCK FTSFLNLWWYLTEQRKERSGSSFRRMCRDEFLHYLRIREWQDLVGQLRSI TH_0802|M.thermoresistible__bu FMSYLNLWRYLTEQRKERSGNSFRRMCREEFLHYLRIREWQDLVGQLRSI MMAR_2947|M.marinum_M FMSYLNLWRYLGEQRRALSRSAFRRMCRNDFLHYLRIREWQDLVGQLRSI MAV_2737|M.avium_104 FMSYLNLWRYLREQRKELSGNQFRRLCRAEFLHYLRIREWQDLVGQLRGI * ::**** ** :** * . ***:** :******************.* MAB_0056c|M.abscessus_ATCC_199 ARDLGIRE----SGERADPGLVHAALIAGLLSHIGLREGDT--------- MSMEG_6587|M.smegmatis_MC2_155 ARDIGIRE----SDEPADPARIHAALTAGLLSHVGLREGDT--------- Mvan_5766|M.vanbaalenii_PYR-1 CRDIGIRE----QDEPADPAAVHAALAAGLLSHVGMRDTDG--------- Mflv_1063|M.gilvum_PYR-GCK CRDLGIRE----QDEPADPRSVHAALTAGLLSHVGMRDTDG--------- TH_0802|M.thermoresistible__bu ARDIGIRES--PDPEPAAPDRIHAALLAGLLSHVGMRDDQRDRKSRDRAR MMAR_2947|M.marinum_M CRDLGLAESGPQSDDAAEPARVHAALLAGLLSHVGMRREDG--------- MAV_2737|M.avium_104 AGELGITE---ESGEPADPARVHAALLAGLLSHVGMRREDS--------- . ::*: * . : * * :**** ******:*:* : MAB_0056c|M.abscessus_ATCC_199 ----RDYSGARNTKFVLAPGSVLTKKPPRWVVVADLVETSRLFGRIAARV MSMEG_6587|M.smegmatis_MC2_155 ----RDYTGARNTKFVLAPGSVLTKKPPRWIVVADLVETSRLFGRIAARI Mvan_5766|M.vanbaalenii_PYR-1 ----RSYQGARNAKFVLAPGSVLSKRPPRWVVVADLVETSRLFGRTAARI Mflv_1063|M.gilvum_PYR-GCK ----RAYDGARNAKFVLAPGSVLSRRPPRWVVVADLVETSRLFGRTAARI TH_0802|M.thermoresistible__bu DRGPREYLGARNTRFVLAPGSVLTRQPPRWVVVAELVETSRLYGRIAARI MMAR_2947|M.marinum_M ----REYLGARNSRFVLAPGSALTKRPPRWVVVAELVETSRLYGRIAARI MAV_2737|M.avium_104 ----REFAGARNSRFVLAPGSVLSKRPPRWVVVAELVETTRLYGRTAARI * : ****::*******.*:::****:***:****:**:** ***: MAB_0056c|M.abscessus_ATCC_199 EPQAVERLAGDLVHKTYSEPHWDAERGAVMAFERVTLYGLPLVPRRRVGY MSMEG_6587|M.smegmatis_MC2_155 EPEAVERVAGHLVQRTYSEPHWDARRGAVMASERVTLYGLPLVPRRRVNY Mvan_5766|M.vanbaalenii_PYR-1 EPETVERVAGHLVQRTYSEPHWDAERGAVMAYERVTLYGLPLVARRRVGY Mflv_1063|M.gilvum_PYR-GCK EPDTVERVAGHVLQRTYSEPHWDAERGAVMAYERVTLYGLPLVARRRIGY TH_0802|M.thermoresistible__bu DPQTVERVGAHLVQRGYSEPHWDAQRGAAMAYERVTLYGLPVVPRRRVGY MMAR_2947|M.marinum_M QPEVVERVAGELAQRSHSEPHWDTKRGEVMAYERVTLYGLPLAARRRVGY MAV_2737|M.avium_104 QPEAVERVAGDLVQRSHSEPHWDPDRGEVMAYERVTLYGLPLVSRRRVGY :*:.***:...: :: :******. ** .** *********:..***:.* MAB_0056c|M.abscessus_ATCC_199 AQVDPELARELFIRHALVEGDWQSKHHFLRDNARLLRELSELEDKARRRD MSMEG_6587|M.smegmatis_MC2_155 AQIDPVVSRELFIRHALVEGEWQTRHHFFRDNARLREEVEEMEERARRRD Mvan_5766|M.vanbaalenii_PYR-1 AQVDPEAARDLFIRHALVEGDWQTKHHFFRDNARLREELAELEDRARRRD Mflv_1063|M.gilvum_PYR-GCK GQVDPEVSRDLFIRHALVEGDWRTKHHFFRDNARLREELAGLEDRARRRD TH_0802|M.thermoresistible__bu ATVEPEVARELFIRHALVEGDWHTRHRFFHDNARLRDELAALEDRARRRD MMAR_2947|M.marinum_M SRVEPTVARQLFIRHALVEGDWQTRHHFFADNARLRTQLEELEERARRRG MAV_2737|M.avium_104 ARIDPVLARELFIRHALVEGDWHTRHRFFADNARLRGELEELEERARRRD . ::* :*:**********:*:::*:*: ***** :: :*::****. MAB_0056c|M.abscessus_ATCC_199 LLVGDDEIYALYAARIPADAVSARHFDAWWRKQRHKTPNLLTFTRDELLR MSMEG_6587|M.smegmatis_MC2_155 LLVGDDEIFALYDARIPADVVSARHFDAWWKKQRHKTPDLLTFTREDLLR Mvan_5766|M.vanbaalenii_PYR-1 LLVGDDEVFAFYDARVPADVVSARHFDGWWRKQRHRTPGLLTMTRDDLLR Mflv_1063|M.gilvum_PYR-GCK LLVGDDEIFAFYDARIPADVVSSRHFDGWWRKERHRNPDLLTLTREDLLR TH_0802|M.thermoresistible__bu LLVGDDEIYEFYAARIPDTVVSARHFDAWWKKQRHRTPDLLTMRREDLLR MMAR_2947|M.marinum_M LLVDDDDVYELYDARIPAEVVSARHFDTWWKKQRHQTPDLLTFTRNELLR MAV_2737|M.avium_104 LVVGDDDVYALYDARIPADVVSARHFDAWWKKQRHQTPDLLTFTRADLLR *:*.**::: :* **:* .**:**** **:*:**:.*.***: * :*** MAB_0056c|M.abscessus_ATCC_199 TADAG---ADMPDTWRAGDVALPVTYRFEPGAADDGVSVHIPVEVLARLG MSMEG_6587|M.smegmatis_MC2_155 TDDA----ADHPDTWRAGDLELPLSYRYQPGAADDGVTVHVPVGVLARLG Mvan_5766|M.vanbaalenii_PYR-1 NEAG----AEQPDAWQAGDLSLPLSYRYDPGSADDGVTVHVPVDVLARLG Mflv_1063|M.gilvum_PYR-GCK NVSDTHTDTEKPDTWQAGDLNLPLSYRFDPGSSDDGVTVHVPVDVLARLG TH_0802|M.thermoresistible__bu TDDAD---AEQPDTWQSGDVELPLSYRFEPGAADDGVTVHVPVHVLARLG MMAR_2947|M.marinum_M SDDPA--DTDRPDAWQTDDAALPLTYRFEPGAADDGVTVHVPVDVLARLG MAV_2737|M.avium_104 TEETG--DADRPDSWRAGDVTLPLTYRFQPGAADDGVTVHVPIDVLARLG . :: **:*::.* **::**::**::****:**:*: ****** MAB_0056c|M.abscessus_ATCC_199 GDEFAWHVPALREELVTALIKSLPKDLRRNFVPAPDTARAVLQNLDPGSE MSMEG_6587|M.smegmatis_MC2_155 GENFAWQVPALREELVTALIKSLPKDLRRNFVPAPDTARAILPHLDPGTG Mvan_5766|M.vanbaalenii_PYR-1 GDEFAWQVPALREELLTALIKSLPKDLRRNFVPAPDTARALLASITPDSG Mflv_1063|M.gilvum_PYR-GCK GDDFAWQVPALREELLTALIKSLPKDLRRNFVPAPDTARALLNAITPDSG TH_0802|M.thermoresistible__bu GDDFAWQVPALREELITELIRSLPKDLRRNFVPAPDTARALLTTLQPGDE MMAR_2947|M.marinum_M DDQFAWQVPAFREELVTELIRSLPKDLRRNFVPAPDAARAVLAGIDPAKE MAV_2737|M.avium_104 GDEFAWQVPALREELVTALIRSLPKDLRRNFVPAPDTARAVLGAIDPAAE .::***:***:****:* **:***************:***:* : * MAB_0056c|M.abscessus_ATCC_199 PLVYALARELHRLSGIRVPTDAFDLDKVPPHLRVTFVVESADGAEVARDK MSMEG_6587|M.smegmatis_MC2_155 SLLDAVQRELRRRTGILVPVDAFDLDKVPPHLRVTFAVENSDGAEVARGK Mvan_5766|M.vanbaalenii_PYR-1 PLLDAIQRELRRRTGILVPIDAFDLDKLPPHLRVTFAVEAADGTVVSRGK Mflv_1063|M.gilvum_PYR-GCK PLLDAVQRELRRRTGILVPIDAFDLSKLPPHLRVTFAVEDADGSVVSRGK TH_0802|M.thermoresistible__bu PLLEAVQRELHRRTGILVPIDAFDLDRLPAHLRVTFAVEGPDGTEVARGK MMAR_2947|M.marinum_M PLLQALQRELRRRSGVLVPIDAFDLTKLPPHLRVNFAVESADGTEVARGK MAV_2737|M.avium_104 PLLPALQRELRRRSGVSVPIDAFDLDKLPAHLRMTFAVESTDGTELARGK .*: *: ***:* :*: ** ***** ::*.***:.*.** .**: ::*.* MAB_0056c|M.abscessus_ATCC_199 NLSALQQRLADSTRQAVATAVAGQWERSGLRAWPGDLPELPHTVEQVSG- MSMEG_6587|M.smegmatis_MC2_155 DIETLREQLAVPVAQAVAEAVDDGLQRTGLRAWPDDLDELPRTVENVSG- Mvan_5766|M.vanbaalenii_PYR-1 DLGELQQQLAAPSRQAVAATVAGDLERTGLRDWPPELDELPRVVERKGAT Mflv_1063|M.gilvum_PYR-GCK NLDELQQQLAAPTRQAVAATVAGDLERTGLRDWPADLDELPRVVESAGAS TH_0802|M.thermoresistible__bu DLAALQERLAGTTRRAVADAVGADLERTGLRDWPEDLEELPRTVERR--- MMAR_2947|M.marinum_M DLKALQAELAAPAQRAVADAVAGDLERKGLRAWPDDVDELARVVERSVG- MAV_2737|M.avium_104 DLRALQERLTTPARQAVADTVGARLQRTGLRGWPDDLDELPRVVQRSLD- :: *: .*: . :*** :* :*.*** ** :: **.:.*: MAB_0056c|M.abscessus_ATCC_199 GHTVRGYPALVDAGTSVDIHVFATESEQRAAMATGARRLLRLSIPSPMKT MSMEG_6587|M.smegmatis_MC2_155 GHTVRGYPGFVDTGKAVDIRVFANPIERDAAMGPGLRRLLRLSVPSPVKA Mvan_5766|M.vanbaalenii_PYR-1 GHLVRGYPALVDAGKAADIKVFATKAEQDAAMGPGCRRLLLTAGPSVTKG Mflv_1063|M.gilvum_PYR-GCK EHVVRGYPALVPAGASVAIKVFATKDEQDAVMARGSRRLLLLAAPSVTKT TH_0802|M.thermoresistible__bu --AVRGYPALVDTGPAVDLRVLPTEAEQSAAMRPGLRRLLRLTVPSPVKA MMAR_2947|M.marinum_M GRAVRGFPGFVDQGPHVDLRVFATSAERDHAMAPGTRRLVRLGVAAPLKA MAV_2737|M.avium_104 GRTVRGYPAFVDTGAAVDLRVFATSAEQVRMMGAGLRRLVRLSIPSPAKA ***:*.:* * . ::*:.. *: * * ***: .: * MAB_0056c|M.abscessus_ATCC_199 VERGLDPRSRLLLSSNPDGPLSALLDDCADAATDLLAPVPVWTRAEFTAL MSMEG_6587|M.smegmatis_MC2_155 IERGLGTRTRLALNANPDGNLAALLEDCADAAADTLVRQIVWTRADFTVL Mvan_5766|M.vanbaalenii_PYR-1 VERSLDTRTRLVLGTNPDGSLAALIDDCAAAAVQVLVPAPAWTREEFAAA Mflv_1063|M.gilvum_PYR-GCK VERGLDTRTRLLLGNNPDGSLSALLEDCAQAAVQILVPDPVWTKKEFAAA TH_0802|M.thermoresistible__bu VERALDPRARLVLGNNPHGSPTALLEDCADAAVDVLAQTPVWTRAEFLAV MMAR_2947|M.marinum_M VERQLDPRTRLLLGTNPDGSLTALLDDCADAATDALTPGPVWTRAEFVAL MAV_2737|M.avium_104 IARQLDPRTRLALGGNPDGSLPALLEDCADAATDALVPQPVWTRDEFTAL : * *..*:** *. **.* .**::*** **.: *. .**: :* . MAB_0056c|M.abscessus_ATCC_199 RDRAAQSLAATTLDIVRRVEKVVQAWSELQVALPTKAPAAQSEAIADMRD MSMEG_6587|M.smegmatis_MC2_155 VQRAAKELGATTQAAVTRVEKVLAAAHEVGVALPDKPPAAQVDAVEDIRL Mvan_5766|M.vanbaalenii_PYR-1 RKRLAANIVATTADVVRRVEKVLVALHEVEVALPSKPTPAQADAIADIRG Mflv_1063|M.gilvum_PYR-GCK RQRLAAGLAQTTADIVRRVQKVLAALHEVELAVPKQPSPAQADAIADIRA TH_0802|M.thermoresistible__bu RDRVAAKLAATTQNVVGRVQHVLAAAQRVQLALPDPPPPTQADAVADIRD MMAR_2947|M.marinum_M CADVAKALVPMTIDIVGRVAKVLAAAQEVQLALPAKPPSAQTDAIADIRA MAV_2737|M.avium_104 RQRVAKTLGPNTIELVGRVEQVLAAAQQVQLALPATPPPAQADAVADIRA * : * * ** :*: * .: :*:* ...:* :*: *:* MAB_0056c|M.abscessus_ATCC_199 QLDRLLDAGFVAATGAARLTDLARYVNAIGKRLERLPQGVEADRERMHRV MSMEG_6587|M.smegmatis_MC2_155 QLERLLPKGFVTATGVARLTDLTRYVTAIARRLERLPHAIGADRERMARV Mvan_5766|M.vanbaalenii_PYR-1 QLARLVPPGFVAATGAARLGDLARYLTAIGRRLERLPHAPAADRERMERV Mflv_1063|M.gilvum_PYR-GCK QLSRLVPTGFVTATGAAKLGDLTRYLTAIDRRLERLPHALGADRERMDRV TH_0802|M.thermoresistible__bu QLGRLLPAGFVTASGAGRLADLTRYLTAIERRLERLPHAVAADRDRMARV MMAR_2947|M.marinum_M QLDRLVPPGFVAATGRAHLGDLARYLIAIRRRLDRLPHAVAADRDRMERV MAV_2737|M.avium_104 QLDRLLPAGFVTATGGARLGDLTRYLSAIRRRLDGLARAGQADRDRMRRV ** **: ***:*:* .:* **:**: ** :**: *.:. ***:** ** MAB_0056c|M.abscessus_ATCC_199 HAVEDAYDDLLRDLPAGRADDPDIRDIAWFIEELRVSLWAQQLGTARAVS MSMEG_6587|M.smegmatis_MC2_155 HAVEDAYDDLVRALSPARAAAHDVSAIAWQIEELRVSLWAQQLGTPRPVS Mvan_5766|M.vanbaalenii_PYR-1 AAVQAEYDDLRRALSPGRAAATDVQDIARMIEELRVSLWAQQLGTARPVS Mflv_1063|M.gilvum_PYR-GCK AAVQDAYDDLRAALSPARAAAPEVVDIAWMIEELRVSLWAQQLGTARPIS TH_0802|M.thermoresistible__bu HAVQEAYEELVAAVSPARAARPDIAEIRWMIEELRVSLWAQQLGTARPVS MMAR_2947|M.marinum_M QAVVEAYDELVHALPLARASAADVRDIGRQIEELRVSLWAQQLGTPRPVS MAV_2737|M.avium_104 HAAQHAYDELVDELPEAAKTAADVRDIAWQIEELRVSLWAQQLGTPRPVS *. *::* :. . :: * ***************.*.:* MAB_0056c|M.abscessus_ATCC_199 EQRILKAINAAR------------- MSMEG_6587|M.smegmatis_MC2_155 EQRIYKAIDAVAR------------ Mvan_5766|M.vanbaalenii_PYR-1 EQRIYRAIDAVGVAGPGGGR----- Mflv_1063|M.gilvum_PYR-GCK EQRIYRALNAAETGR---------- TH_0802|M.thermoresistible__bu EQRIYRAIDGVQL------------ MMAR_2947|M.marinum_M EQRIYRAIDAVHHSDTER------- MAV_2737|M.avium_104 EQRIHRAIDAARQRYRVALPPTLNL **** :*::..