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AAVAEPSFPVSGAQLRGRLDGLTIRDAARLGRRLKKLRGAAPDKLRQLADQIAAAEAVVAARHAAVPAVS YPDLPVSERRREIADAIRAHQVVVIAGETGSGKTTQLPKVCLEAGRGIRGTIGHTQPRRLAARTVAQRIA DELGSPLGETVGYTVRFTDQVSDRTLIKLMTDGILLAEIQRDRRLLRYDTLILDEAHERSLNIDFLLGYL RALLPRRPDLKLIITSATIEPRRFSEHFANAPVIEVSGRTYPVEIRYRPLEIALPSATADDPDDPDHEIV RTETRDEVEAIVDAIAELEAEPPGDVLVFLSGEREIRDTAEALTGLKHTEVLPLYARLPTAEQQKVFAPH TGRRVVLATNVAETSLTVPGIRYVVDPGNARISRYSRRLKVQRLPIEPISQASAAQRAGRCGRVAPGVCI RLYSEADFAARPRYTEPEILRTNLAAVLLQMAALQLGDIENFPFLDPPDRRSVRDGVQLLTELGAFDRQG AITERGRRLARLPVDPRLGRMILAAQTEGCVREMLVLAAALSIPDPRERPSDREEAARQKHARFADEHSD FMSYLNLWRYLREQRKELSGNQFRRLCRAEFLHYLRIREWQDLVGQLRGIAGELGITEESGEPADPARVH AALLAGLLSHVGMRREDSREFAGARNSRFVLAPGSVLSKRPPRWVVVAELVETTRLYGRTAARIQPEAVE RVAGDLVQRSHSEPHWDPDRGEVMAYERVTLYGLPLVSRRRVGYARIDPVLARELFIRHALVEGDWHTRH RFFADNARLRGELEELEERARRRDLVVGDDDVYALYDARIPADVVSARHFDAWWKKQRHQTPDLLTFTRA DLLRTEETGDADRPDSWRAGDVTLPLTYRFQPGAADDGVTVHVPIDVLARLGGDEFAWQVPALREELVTA LIRSLPKDLRRNFVPAPDTARAVLGAIDPAAEPLLPALQRELRRRSGVSVPIDAFDLDKLPAHLRMTFAV ESTDGTELARGKDLRALQERLTTPARQAVADTVGARLQRTGLRGWPDDLDELPRVVQRSLDGRTVRGYPA FVDTGAAVDLRVFATSAEQVRMMGAGLRRLVRLSIPSPAKAIARQLDPRTRLALGGNPDGSLPALLEDCA DAATDALVPQPVWTRDEFTALRQRVAKTLGPNTIELVGRVEQVLAAAQQVQLALPATPPPAQADAVADIR AQLDRLLPAGFVTATGGARLGDLTRYLSAIRRRLDGLARAGQADRDRMRRVHAAQHAYDELVDELPEAAK TAADVRDIAWQIEELRVSLWAQQLGTPRPVSEQRIHRAIDAARQRYRVALPPTLNL*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. avium 104 | MAV_2737 | hrpA | - | 100% (1317) | ATP-dependent helicase HrpA |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. gilvum PYR-GCK | Mflv_1063 | - | 0.0 | 73.37% (1303) | ATP-dependent helicase HrpA |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | MAB_0056c | - | 0.0 | 73.85% (1300) | ATP-dependent helicase HrpA |
M. marinum M | MMAR_2947 | - | 0.0 | 80.03% (1302) | HrpA-like helicase |
M. smegmatis MC2 155 | MSMEG_6587 | hrpA | 0.0 | 76.38% (1308) | ATP-dependent helicase HrpA |
M. thermoresistible (build 8) | TH_0802 | hrpA | 0.0 | 75.72% (1318) | ATP-dependent helicase HrpA |
M. ulcerans Agy99 | - | - | - | - | - |
M. vanbaalenii PYR-1 | Mvan_5766 | - | 0.0 | 75.08% (1292) | ATP-dependent helicase HrpA |
CLUSTAL 2.0.9 multiple sequence alignment Mflv_1063|M.gilvum_PYR-GCK ----MPEQPSTDVRALRARLDGLTISDAARLGRRLRQQR-TPDPAALARL Mvan_5766|M.vanbaalenii_PYR-1 ----MPEPSRTDVRALRARLDDLTISDAARLGRRLRQLR-DPSEEQLGKL TH_0802|M.thermoresistible__bu -----VSDPSHDVRALRARLDGLTHRDAARLGRRLRQVR-GAKPEQLQRI MAB_0056c|M.abscessus_ATCC_199 ------MSELS-RTELRARLDGVTFRDASRLGRRLKNQR-DTNPDALTKL MSMEG_6587|M.smegmatis_MC2_155 ------MSERQELRELRARLDGLTIRDAARLGRRLKNLRGDDLTKNFAKI MAV_2737|M.avium_104 MAAVAEPSFPVSGAQLRGRLDGLTIRDAARLGRRLKKLR-GAAPDKLRQL MMAR_2947|M.marinum_M -------MADLSVAQLRSRLDGLSTRDAVRLGRRLKGLR-GAKPERLQQL **.***.:: ** ******: * : :: Mflv_1063|M.gilvum_PYR-GCK AE----RFTAAEALVATRLAAVPEITYPDLPVSERRDDIAAAIAANQVVI Mvan_5766|M.vanbaalenii_PYR-1 AK----QFDTAEALVASRLAAVPQISYPDLPVTERRDEIAAAIAANQVVI TH_0802|M.thermoresistible__bu AE----QIAAGEALVAARAAAVPEISYPDLPVSERRHEIAEAIANHQVVV MAB_0056c|M.abscessus_ATCC_199 AE----QITAAEALIATRAAAVPVITYPDLPVSAHREELAHAISAHQVVV MSMEG_6587|M.smegmatis_MC2_155 EQ----QIAQAEALVLTRQAAVPQITYPDLPVTQRRDDLAKAIAENQVVV MAV_2737|M.avium_104 AD----QIAAAEAVVAARHAAVPAVSYPDLPVSERRREIADAIRAHQVVV MMAR_2947|M.marinum_M TEQIAVQISAAEALIATRQAAVPTITYPDLPVSERRQEIAEAIRANQVVV . :: .**:: :* **** ::******: :* ::* ** :***: Mflv_1063|M.gilvum_PYR-GCK VAGETGSGKTTQLPKICLEMGRGIRGTIGHTQPRRLAARTVATRIAEELG Mvan_5766|M.vanbaalenii_PYR-1 VAGETGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAARIAEELG TH_0802|M.thermoresistible__bu VAGETGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAQRIADELG MAB_0056c|M.abscessus_ATCC_199 VAGATGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAERIAEELG MSMEG_6587|M.smegmatis_MC2_155 VAGATGSGKTTQLPKICLELGRGIRGTIGHTQPRRLAARTVAQRIADELG MAV_2737|M.avium_104 IAGETGSGKTTQLPKVCLEAGRGIRGTIGHTQPRRLAARTVAQRIADELG MMAR_2947|M.marinum_M VAGETGSGKTTQLPKICLDIGRGVRGTIGHTQPRRLAARTVAQRIADELQ :** ***********:**: ***:****************** ***:** Mflv_1063|M.gilvum_PYR-GCK TPLGEAVGYTVRFTDQASDRTLVKLMTDGILLAEVQRDRRLLRYDTLIID Mvan_5766|M.vanbaalenii_PYR-1 TPLGEAVGYTVRFTDQASDRTLVKLMTDGILLAEVQRDRRLLRYDTLIID TH_0802|M.thermoresistible__bu TPLGEAVGYTVRFTDQAGDRTLVKLMTDGILLAEIQRDRRLLRYDTIIID MAB_0056c|M.abscessus_ATCC_199 TQLGETVGYTVRFTDQASDRTLVKLMTDGILLAEIQRDRRLLRYDTLILD MSMEG_6587|M.smegmatis_MC2_155 TPLGEAVGYTVRFTDQASDSTLVKLMTDGILLAEIQRDRRLLRYDTLILD MAV_2737|M.avium_104 SPLGETVGYTVRFTDQVSDRTLIKLMTDGILLAEIQRDRRLLRYDTLILD MMAR_2947|M.marinum_M TPLGDAVGYAVRFTDQVSERTLVKLMTDGILLAEIQRDRRLLRYDTLILD : **::***:******..: **:***********:***********:*:* Mflv_1063|M.gilvum_PYR-GCK EAHERSLNIDFLLGYLRRLLPRRPDLKVIVTSATIEPERFARFFAGGEHG Mvan_5766|M.vanbaalenii_PYR-1 EAHERSLNIDFLLGYLRQLLPRRPDLKVIVTSATIEPERFAAHFAG---- TH_0802|M.thermoresistible__bu EAHERSLNIDFLLGYLKGLLPRRPDLKVIITSATIEPRRFAKHFDA---- MAB_0056c|M.abscessus_ATCC_199 EAHERSLNIDFLLGYLRELLPRRPDLKIIVTSATIEPQRFSAHFGN---- MSMEG_6587|M.smegmatis_MC2_155 EAHERSLNIDFLLGYLRELLPRRPDLKVIVTSATIEPERFSRHFGD---- MAV_2737|M.avium_104 EAHERSLNIDFLLGYLRALLPRRPDLKLIITSATIEPRRFSEHFAN---- MMAR_2947|M.marinum_M EAHERSLNIDFLLGYLRELLPRRPDLKLIVTSATIEPQRFAAHFGG---- ****************: *********:*:*******.**: .* Mflv_1063|M.gilvum_PYR-GCK SGAGAPIVEVSGRTYPVEIRHRPLEVAVSAAD----DDDPDDPDHEVVRT Mvan_5766|M.vanbaalenii_PYR-1 ----APIVEVSGRTYPVEIRYRPLEVTVPGQD----GEDPDDPDHEVVRT TH_0802|M.thermoresistible__bu -----PVVEVSGRTYPVEIRYRPLEVPAGTDT----ADDPDDPDHEIVRT MAB_0056c|M.abscessus_ATCC_199 ----APIVEVSGRTYPVEIRYRPLEVPVHGTSGAKAEDEPDDPDHEIVRT MSMEG_6587|M.smegmatis_MC2_155 ----APIVEVSGRTYPVEIRYRPLEVPAPTSD----DEDPDDPDHEIVRT MAV_2737|M.avium_104 ----APVIEVSGRTYPVEIRYRPLEIALPSAT-ADD---PDDPDHEIVRT MMAR_2947|M.marinum_M ----APIIEVSGRTYPVAIRYRPLEVPVSTGS-PEDSSDPDDPDHEIVRT *::********* **:****:. *******:*** Mflv_1063|M.gilvum_PYR-GCK ELRDPTEAIIDAVAELESEPRGDVLVFLSGEREIRDTAEALRAVTDPGHT Mvan_5766|M.vanbaalenii_PYR-1 ELRDPTEAIIDAVAELEAEPPGDVLVFLSGEREIRDTAEALRAVVDPGHT TH_0802|M.thermoresistible__bu EIRDQTEAIIDAVRELDAEPPGDVLVFLSGEREIRDTAEALRGTLDP-DV MAB_0056c|M.abscessus_ATCC_199 ELRDQTEAIADAVRELQNEPPGDVLVFLSGEREIRDTSEALRDIVRA-GT MSMEG_6587|M.smegmatis_MC2_155 EVRDPTEAIVDAVRELEAEPPGDVLVFLSGEREIRDTAEALKDLR---NT MAV_2737|M.avium_104 ETRDEVEAIVDAIAELEAEPPGDVLVFLSGEREIRDTAEALTGLK---HT MMAR_2947|M.marinum_M ETRDEVEAIVDAVHELQNEAPGDVLVFLSGEREIRDTAEALSGLE---HT * ** .*** **: **: *. ****************:*** . Mflv_1063|M.gilvum_PYR-GCK EVLPLYARLPTAEQQKVFSPSRAARRIVLATNVAETSLTVPGIRYVVDPG Mvan_5766|M.vanbaalenii_PYR-1 EVLPLYARLPTAEQQKVFHPGRTARRIVLATNVAETSLTVPGIRYVVDPG TH_0802|M.thermoresistible__bu EVLPLYARLPTAEQQKVFTPHRLRRRIVLATNVAETSLTVPGIRYVVDPG MAB_0056c|M.abscessus_ATCC_199 EVLPLYARLPTAEQHKVFA-SHTGRRVVLATNVAETSLTVPGIRYVIDPG MSMEG_6587|M.smegmatis_MC2_155 EVLPLYARLPTAEQQKVFQPSHAGRRVVLATNVAETSLTVPGIRYVVDPG MAV_2737|M.avium_104 EVLPLYARLPTAEQQKVFA-PHTGRRVVLATNVAETSLTVPGIRYVVDPG MMAR_2947|M.marinum_M EVLPLYARLPTAEQQKVFA-PHTGRRVVLATNVAETSLTVPGIRYVVDPG **************:*** : **:*******************:*** Mflv_1063|M.gilvum_PYR-GCK TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCIRLYSEQDF Mvan_5766|M.vanbaalenii_PYR-1 TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCIRLYSEQDF TH_0802|M.thermoresistible__bu TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRVAPGVCIRLYSEEDF MAB_0056c|M.abscessus_ATCC_199 TARISRYSRRTKVQRLPIEPISQASAAQRSGRSGRTAPGICIRLYSEQDF MSMEG_6587|M.smegmatis_MC2_155 TARISRYSRRTKVQRLPIEPISQASAAQRAGRSGRTAPGVCIRLYSEEDF MAV_2737|M.avium_104 NARISRYSRRLKVQRLPIEPISQASAAQRAGRCGRVAPGVCIRLYSEADF MMAR_2947|M.marinum_M NARISRYSRRLKVQRLPIEPISQASAAQRAGRCGRVAPGICIRLYSEDDF .********* ******************:**.**.***:******* ** Mflv_1063|M.gilvum_PYR-GCK ESRPRYTDPEILRTNLAAVILQMAALGFGDIEAFGFLDPPDARSIRDGVA Mvan_5766|M.vanbaalenii_PYR-1 EARPRYTDPEILRTNLAAVILQMAALGFGDIEGFGFLDPPDARSIRDGVA TH_0802|M.thermoresistible__bu ESRPEFTEPEILRTNLAAVILQMAALGFGAVEDFPFLDPPDQRSIRDGVA MAB_0056c|M.abscessus_ATCC_199 EARPRYTDPEILRTNLAAVILQMAALQLGDIENFPFLDPPDKRSIRDGVQ MSMEG_6587|M.smegmatis_MC2_155 ESRPRYTDPEILRTNLAAVILQMSALGLGDIENFPFLDPPDARSIRDGIQ MAV_2737|M.avium_104 AARPRYTEPEILRTNLAAVLLQMAALQLGDIENFPFLDPPDRRSVRDGVQ MMAR_2947|M.marinum_M AARPQYTDPEILRTNLAAVILQMAALQLGEIENFGFLDPPDRRSVRDGVQ :**.:*:***********:***:** :* :* * ****** **:***: Mflv_1063|M.gilvum_PYR-GCK LLQELGAFD----RQG--------------ELTDIGRRLAQIPVDPRLGR Mvan_5766|M.vanbaalenii_PYR-1 LLQELGAFD----QQA--------------DLTDIGRRLAQIPVDPRLGR TH_0802|M.thermoresistible__bu LLRELGAFD----ERG--------------EITDVGRRLAQLPVDPRLGR MAB_0056c|M.abscessus_ATCC_199 LLQELGAFS----ADG--------------TITELGRRLARLPLDPRIGR MSMEG_6587|M.smegmatis_MC2_155 LLQELGAFDTSSAAGGGNSASAAGGGNSVPALTETGRRLARLPLDPRIGR MAV_2737|M.avium_104 LLTELGAFD----RQG--------------AITERGRRLARLPVDPRLGR MMAR_2947|M.marinum_M LLQELGAFD----PTG--------------AITDLGRRLARLPVDPRLGR ** *****. . :*: *****::*:***:** Mflv_1063|M.gilvum_PYR-GCK MILQADHEGCVREMLVLAAALSIPDPRERPADREDAARQKHARFADEHSD Mvan_5766|M.vanbaalenii_PYR-1 MILQADAEGCVREMLVLAAALSIPDPRERPADKEEAARQKHARFADQHSD TH_0802|M.thermoresistible__bu MVLQAETEGCVREVLVLAAALSIPDPRERPLDKEDAARAKHARFADEHSD MAB_0056c|M.abscessus_ATCC_199 MILQADAEGCVEEILVLAAALSIPDPRERPADREEAARQKHARFADDHSD MSMEG_6587|M.smegmatis_MC2_155 MILQADAEGCVREALVLAAALSIPDPRERPSDREEAARQKHARFADEHSD MAV_2737|M.avium_104 MILAAQTEGCVREMLVLAAALSIPDPRERPSDREEAARQKHARFADEHSD MMAR_2947|M.marinum_M MILQAGVEGCLREVLVLAAALTIPDPRERPTDREEAARQKHARFADEDSD *:* * ***:.* *******:******** *:*:*** *******:.** Mflv_1063|M.gilvum_PYR-GCK FTSFLNLWWYLTEQRKERSGSSFRRMCRDEFLHYLRIREWQDLVGQLRSI Mvan_5766|M.vanbaalenii_PYR-1 FTSYLNLWHYLTEQRKERSGSSFRRMCRDEFLHYLRIREWQDLVGQLRGI TH_0802|M.thermoresistible__bu FMSYLNLWRYLTEQRKERSGNSFRRMCREEFLHYLRIREWQDLVGQLRSI MAB_0056c|M.abscessus_ATCC_199 FIAYLNLWRYLQDQRSQLSGSAFRRMCRNEFLHYLRIREWQDLVGQLRSI MSMEG_6587|M.smegmatis_MC2_155 FISYLNLWNYLREQRNELSGNAFRRMCRDEFLHYLRIREWQDLVGQLRSI MAV_2737|M.avium_104 FMSYLNLWRYLREQRKELSGNQFRRLCRAEFLHYLRIREWQDLVGQLRGI MMAR_2947|M.marinum_M FMSYLNLWRYLGEQRRALSRSAFRRMCRNDFLHYLRIREWQDLVGQLRSI * ::**** ** :** * . ***:** :******************.* Mflv_1063|M.gilvum_PYR-GCK CRDLGIRE----QDEPADPRSVHAALTAGLLSHVGMRDTDG--------- Mvan_5766|M.vanbaalenii_PYR-1 CRDIGIRE----QDEPADPAAVHAALAAGLLSHVGMRDTDG--------- TH_0802|M.thermoresistible__bu ARDIGIRES--PDPEPAAPDRIHAALLAGLLSHVGMRDDQRDRKSRDRAR MAB_0056c|M.abscessus_ATCC_199 ARDLGIRE----SGERADPGLVHAALIAGLLSHIGLREGDT--------- MSMEG_6587|M.smegmatis_MC2_155 ARDIGIRE----SDEPADPARIHAALTAGLLSHVGLREGDT--------- MAV_2737|M.avium_104 AGELGITE---ESGEPADPARVHAALLAGLLSHVGMRREDS--------- MMAR_2947|M.marinum_M CRDLGLAESGPQSDDAAEPARVHAALLAGLLSHVGMRREDG--------- . ::*: * . : * * :**** ******:*:* : Mflv_1063|M.gilvum_PYR-GCK ----RAYDGARNAKFVLAPGSVLSRRPPRWVVVADLVETSRLFGRTAARI Mvan_5766|M.vanbaalenii_PYR-1 ----RSYQGARNAKFVLAPGSVLSKRPPRWVVVADLVETSRLFGRTAARI TH_0802|M.thermoresistible__bu DRGPREYLGARNTRFVLAPGSVLTRQPPRWVVVAELVETSRLYGRIAARI MAB_0056c|M.abscessus_ATCC_199 ----RDYSGARNTKFVLAPGSVLTKKPPRWVVVADLVETSRLFGRIAARV MSMEG_6587|M.smegmatis_MC2_155 ----RDYTGARNTKFVLAPGSVLTKKPPRWIVVADLVETSRLFGRIAARI MAV_2737|M.avium_104 ----REFAGARNSRFVLAPGSVLSKRPPRWVVVAELVETTRLYGRTAARI MMAR_2947|M.marinum_M ----REYLGARNSRFVLAPGSALTKRPPRWVVVAELVETSRLYGRIAARI * : ****::*******.*:::****:***:****:**:** ***: Mflv_1063|M.gilvum_PYR-GCK EPDTVERVAGHVLQRTYSEPHWDAERGAVMAYERVTLYGLPLVARRRIGY Mvan_5766|M.vanbaalenii_PYR-1 EPETVERVAGHLVQRTYSEPHWDAERGAVMAYERVTLYGLPLVARRRVGY TH_0802|M.thermoresistible__bu DPQTVERVGAHLVQRGYSEPHWDAQRGAAMAYERVTLYGLPVVPRRRVGY MAB_0056c|M.abscessus_ATCC_199 EPQAVERLAGDLVHKTYSEPHWDAERGAVMAFERVTLYGLPLVPRRRVGY MSMEG_6587|M.smegmatis_MC2_155 EPEAVERVAGHLVQRTYSEPHWDARRGAVMASERVTLYGLPLVPRRRVNY MAV_2737|M.avium_104 QPEAVERVAGDLVQRSHSEPHWDPDRGEVMAYERVTLYGLPLVSRRRVGY MMAR_2947|M.marinum_M QPEVVERVAGELAQRSHSEPHWDTKRGEVMAYERVTLYGLPLAARRRVGY :*:.***:...: :: :******. ** .** *********:..***:.* Mflv_1063|M.gilvum_PYR-GCK GQVDPEVSRDLFIRHALVEGDWRTKHHFFRDNARLREELAGLEDRARRRD Mvan_5766|M.vanbaalenii_PYR-1 AQVDPEAARDLFIRHALVEGDWQTKHHFFRDNARLREELAELEDRARRRD TH_0802|M.thermoresistible__bu ATVEPEVARELFIRHALVEGDWHTRHRFFHDNARLRDELAALEDRARRRD MAB_0056c|M.abscessus_ATCC_199 AQVDPELARELFIRHALVEGDWQSKHHFLRDNARLLRELSELEDKARRRD MSMEG_6587|M.smegmatis_MC2_155 AQIDPVVSRELFIRHALVEGEWQTRHHFFRDNARLREEVEEMEERARRRD MAV_2737|M.avium_104 ARIDPVLARELFIRHALVEGDWHTRHRFFADNARLRGELEELEERARRRD MMAR_2947|M.marinum_M SRVEPTVARQLFIRHALVEGDWQTRHHFFADNARLRTQLEELEERARRRG . ::* :*:**********:*:::*:*: ***** :: :*::****. Mflv_1063|M.gilvum_PYR-GCK LLVGDDEIFAFYDARIPADVVSSRHFDGWWRKERHRNPDLLTLTREDLLR Mvan_5766|M.vanbaalenii_PYR-1 LLVGDDEVFAFYDARVPADVVSARHFDGWWRKQRHRTPGLLTMTRDDLLR TH_0802|M.thermoresistible__bu LLVGDDEIYEFYAARIPDTVVSARHFDAWWKKQRHRTPDLLTMRREDLLR MAB_0056c|M.abscessus_ATCC_199 LLVGDDEIYALYAARIPADAVSARHFDAWWRKQRHKTPNLLTFTRDELLR MSMEG_6587|M.smegmatis_MC2_155 LLVGDDEIFALYDARIPADVVSARHFDAWWKKQRHKTPDLLTFTREDLLR MAV_2737|M.avium_104 LVVGDDDVYALYDARIPADVVSARHFDAWWKKQRHQTPDLLTFTRADLLR MMAR_2947|M.marinum_M LLVDDDDVYELYDARIPAEVVSARHFDTWWKKQRHQTPDLLTFTRNELLR *:*.**::: :* **:* .**:**** **:*:**:.*.***: * :*** Mflv_1063|M.gilvum_PYR-GCK NVSDTHTDTEKPDTWQAGDLNLPLSYRFDPGSSDDGVTVHVPVDVLARLG Mvan_5766|M.vanbaalenii_PYR-1 NEAG----AEQPDAWQAGDLSLPLSYRYDPGSADDGVTVHVPVDVLARLG TH_0802|M.thermoresistible__bu TDDAD---AEQPDTWQSGDVELPLSYRFEPGAADDGVTVHVPVHVLARLG MAB_0056c|M.abscessus_ATCC_199 TADAG---ADMPDTWRAGDVALPVTYRFEPGAADDGVSVHIPVEVLARLG MSMEG_6587|M.smegmatis_MC2_155 TDDA----ADHPDTWRAGDLELPLSYRYQPGAADDGVTVHVPVGVLARLG MAV_2737|M.avium_104 TEETG--DADRPDSWRAGDVTLPLTYRFQPGAADDGVTVHVPIDVLARLG MMAR_2947|M.marinum_M SDDPA--DTDRPDAWQTDDAALPLTYRFEPGAADDGVTVHVPVDVLARLG . :: **:*::.* **::**::**::****:**:*: ****** Mflv_1063|M.gilvum_PYR-GCK GDDFAWQVPALREELLTALIKSLPKDLRRNFVPAPDTARALLNAITPDSG Mvan_5766|M.vanbaalenii_PYR-1 GDEFAWQVPALREELLTALIKSLPKDLRRNFVPAPDTARALLASITPDSG TH_0802|M.thermoresistible__bu GDDFAWQVPALREELITELIRSLPKDLRRNFVPAPDTARALLTTLQPGDE MAB_0056c|M.abscessus_ATCC_199 GDEFAWHVPALREELVTALIKSLPKDLRRNFVPAPDTARAVLQNLDPGSE MSMEG_6587|M.smegmatis_MC2_155 GENFAWQVPALREELVTALIKSLPKDLRRNFVPAPDTARAILPHLDPGTG MAV_2737|M.avium_104 GDEFAWQVPALREELVTALIRSLPKDLRRNFVPAPDTARAVLGAIDPAAE MMAR_2947|M.marinum_M DDQFAWQVPAFREELVTELIRSLPKDLRRNFVPAPDAARAVLAGIDPAKE .::***:***:****:* **:***************:***:* : * Mflv_1063|M.gilvum_PYR-GCK PLLDAVQRELRRRTGILVPIDAFDLSKLPPHLRVTFAVEDADGSVVSRGK Mvan_5766|M.vanbaalenii_PYR-1 PLLDAIQRELRRRTGILVPIDAFDLDKLPPHLRVTFAVEAADGTVVSRGK TH_0802|M.thermoresistible__bu PLLEAVQRELHRRTGILVPIDAFDLDRLPAHLRVTFAVEGPDGTEVARGK MAB_0056c|M.abscessus_ATCC_199 PLVYALARELHRLSGIRVPTDAFDLDKVPPHLRVTFVVESADGAEVARDK MSMEG_6587|M.smegmatis_MC2_155 SLLDAVQRELRRRTGILVPVDAFDLDKVPPHLRVTFAVENSDGAEVARGK MAV_2737|M.avium_104 PLLPALQRELRRRSGVSVPIDAFDLDKLPAHLRMTFAVESTDGTELARGK MMAR_2947|M.marinum_M PLLQALQRELRRRSGVLVPIDAFDLTKLPPHLRVNFAVESADGTEVARGK .*: *: ***:* :*: ** ***** ::*.***:.*.** .**: ::*.* Mflv_1063|M.gilvum_PYR-GCK NLDELQQQLAAPTRQAVAATVAGDLERTGLRDWPADLDELPRVVESAGAS Mvan_5766|M.vanbaalenii_PYR-1 DLGELQQQLAAPSRQAVAATVAGDLERTGLRDWPPELDELPRVVERKGAT TH_0802|M.thermoresistible__bu DLAALQERLAGTTRRAVADAVGADLERTGLRDWPEDLEELPRTVERR--- MAB_0056c|M.abscessus_ATCC_199 NLSALQQRLADSTRQAVATAVAGQWERSGLRAWPGDLPELPHTVEQVSG- MSMEG_6587|M.smegmatis_MC2_155 DIETLREQLAVPVAQAVAEAVDDGLQRTGLRAWPDDLDELPRTVENVSG- MAV_2737|M.avium_104 DLRALQERLTTPARQAVADTVGARLQRTGLRGWPDDLDELPRVVQRSLD- MMAR_2947|M.marinum_M DLKALQAELAAPAQRAVADAVAGDLERKGLRAWPDDVDELARVVERSVG- :: *: .*: . :*** :* :*.*** ** :: **.:.*: Mflv_1063|M.gilvum_PYR-GCK EHVVRGYPALVPAGASVAIKVFATKDEQDAVMARGSRRLLLLAAPSVTKT Mvan_5766|M.vanbaalenii_PYR-1 GHLVRGYPALVDAGKAADIKVFATKAEQDAAMGPGCRRLLLTAGPSVTKG TH_0802|M.thermoresistible__bu --AVRGYPALVDTGPAVDLRVLPTEAEQSAAMRPGLRRLLRLTVPSPVKA MAB_0056c|M.abscessus_ATCC_199 GHTVRGYPALVDAGTSVDIHVFATESEQRAAMATGARRLLRLSIPSPMKT MSMEG_6587|M.smegmatis_MC2_155 GHTVRGYPGFVDTGKAVDIRVFANPIERDAAMGPGLRRLLRLSVPSPVKA MAV_2737|M.avium_104 GRTVRGYPAFVDTGAAVDLRVFATSAEQVRMMGAGLRRLVRLSIPSPAKA MMAR_2947|M.marinum_M GRAVRGFPGFVDQGPHVDLRVFATSAERDHAMAPGTRRLVRLGVAAPLKA ***:*.:* * . ::*:.. *: * * ***: .: * Mflv_1063|M.gilvum_PYR-GCK VERGLDTRTRLLLGNNPDGSLSALLEDCAQAAVQILVPDPVWTKKEFAAA Mvan_5766|M.vanbaalenii_PYR-1 VERSLDTRTRLVLGTNPDGSLAALIDDCAAAAVQVLVPAPAWTREEFAAA TH_0802|M.thermoresistible__bu VERALDPRARLVLGNNPHGSPTALLEDCADAAVDVLAQTPVWTRAEFLAV MAB_0056c|M.abscessus_ATCC_199 VERGLDPRSRLLLSSNPDGPLSALLDDCADAATDLLAPVPVWTRAEFTAL MSMEG_6587|M.smegmatis_MC2_155 IERGLGTRTRLALNANPDGNLAALLEDCADAAADTLVRQIVWTRADFTVL MAV_2737|M.avium_104 IARQLDPRTRLALGGNPDGSLPALLEDCADAATDALVPQPVWTRDEFTAL MMAR_2947|M.marinum_M VERQLDPRTRLLLGTNPDGSLTALLDDCADAATDALTPGPVWTRAEFVAL : * *..*:** *. **.* .**::*** **.: *. .**: :* . Mflv_1063|M.gilvum_PYR-GCK RQRLAAGLAQTTADIVRRVQKVLAALHEVELAVPKQPSPAQADAIADIRA Mvan_5766|M.vanbaalenii_PYR-1 RKRLAANIVATTADVVRRVEKVLVALHEVEVALPSKPTPAQADAIADIRG TH_0802|M.thermoresistible__bu RDRVAAKLAATTQNVVGRVQHVLAAAQRVQLALPDPPPPTQADAVADIRD MAB_0056c|M.abscessus_ATCC_199 RDRAAQSLAATTLDIVRRVEKVVQAWSELQVALPTKAPAAQSEAIADMRD MSMEG_6587|M.smegmatis_MC2_155 VQRAAKELGATTQAAVTRVEKVLAAAHEVGVALPDKPPAAQVDAVEDIRL MAV_2737|M.avium_104 RQRVAKTLGPNTIELVGRVEQVLAAAQQVQLALPATPPPAQADAVADIRA MMAR_2947|M.marinum_M CADVAKALVPMTIDIVGRVAKVLAAAQEVQLALPAKPPSAQTDAIADIRA * : * * ** :*: * .: :*:* ...:* :*: *:* Mflv_1063|M.gilvum_PYR-GCK QLSRLVPTGFVTATGAAKLGDLTRYLTAIDRRLERLPHALGADRERMDRV Mvan_5766|M.vanbaalenii_PYR-1 QLARLVPPGFVAATGAARLGDLARYLTAIGRRLERLPHAPAADRERMERV TH_0802|M.thermoresistible__bu QLGRLLPAGFVTASGAGRLADLTRYLTAIERRLERLPHAVAADRDRMARV MAB_0056c|M.abscessus_ATCC_199 QLDRLLDAGFVAATGAARLTDLARYVNAIGKRLERLPQGVEADRERMHRV MSMEG_6587|M.smegmatis_MC2_155 QLERLLPKGFVTATGVARLTDLTRYVTAIARRLERLPHAIGADRERMARV MAV_2737|M.avium_104 QLDRLLPAGFVTATGGARLGDLTRYLSAIRRRLDGLARAGQADRDRMRRV MMAR_2947|M.marinum_M QLDRLVPPGFVAATGRAHLGDLARYLIAIRRRLDRLPHAVAADRDRMERV ** **: ***:*:* .:* **:**: ** :**: *.:. ***:** ** Mflv_1063|M.gilvum_PYR-GCK AAVQDAYDDLRAALSPARAAAPEVVDIAWMIEELRVSLWAQQLGTARPIS Mvan_5766|M.vanbaalenii_PYR-1 AAVQAEYDDLRRALSPGRAAATDVQDIARMIEELRVSLWAQQLGTARPVS TH_0802|M.thermoresistible__bu HAVQEAYEELVAAVSPARAARPDIAEIRWMIEELRVSLWAQQLGTARPVS MAB_0056c|M.abscessus_ATCC_199 HAVEDAYDDLLRDLPAGRADDPDIRDIAWFIEELRVSLWAQQLGTARAVS MSMEG_6587|M.smegmatis_MC2_155 HAVEDAYDDLVRALSPARAAAHDVSAIAWQIEELRVSLWAQQLGTPRPVS MAV_2737|M.avium_104 HAAQHAYDELVDELPEAAKTAADVRDIAWQIEELRVSLWAQQLGTPRPVS MMAR_2947|M.marinum_M QAVVEAYDELVHALPLARASAADVRDIGRQIEELRVSLWAQQLGTPRPVS *. *::* :. . :: * ***************.*.:* Mflv_1063|M.gilvum_PYR-GCK EQRIYRALNAAETGR---------- Mvan_5766|M.vanbaalenii_PYR-1 EQRIYRAIDAVGVAGPGGGR----- TH_0802|M.thermoresistible__bu EQRIYRAIDGVQL------------ MAB_0056c|M.abscessus_ATCC_199 EQRILKAINAAR------------- MSMEG_6587|M.smegmatis_MC2_155 EQRIYKAIDAVAR------------ MAV_2737|M.avium_104 EQRIHRAIDAARQRYRVALPPTLNL MMAR_2947|M.marinum_M EQRIYRAIDAVHHSDTER------- **** :*::..