For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTSAGSTRDHGDPGDAPSVPPPLTDPADTTRPSAAEEARTIAASTNAGTLATLTADGDPWASFVTYGLLD GAPVLCVSNLAEHGRNLATDPRASIAIVAPTAETDPLASARVTLAGRVEAPEGAERAAAREAHLSAVAAA KYYIDYSDFSLWLLRVSRVRWVGGYGRMDSTSGADYTAAEPDPVTPRAAGAIAHLNADHADSLAAMARTL GGYPDTRSATCTGVDRYGLDLRLSTERGMAYTRIGYARPIDSIDELRSAAAELAQRARNT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5737 | - | - | 100% (270) | pyridoxamine 5'-phosphate oxidase-related, FMN-binding |
| M. vanbaalenii PYR-1 | Mvan_5663 | - | 1e-06 | 23.41% (252) | hypothetical protein Mvan_5663 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3869 | - | 3e-05 | 23.29% (249) | hypothetical protein Mb3869 |
| M. gilvum PYR-GCK | Mflv_1085 | - | 1e-126 | 80.22% (273) | pyridoxamine 5'-phosphate oxidase-related, FMN-binding |
| M. tuberculosis H37Rv | Rv3839 | - | 4e-05 | 23.29% (249) | hypothetical protein Rv3839 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1906 | - | 1e-101 | 66.28% (261) | pyridoxamine 5'-phosphate oxidase-related |
| M. marinum M | MMAR_5391 | - | 3e-08 | 26.64% (259) | hypothetical protein MMAR_5391 |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_6519 | - | 1e-123 | 81.13% (265) | pyridoxamine 5'-phosphate oxidase family protein |
| M. thermoresistible (build 8) | TH_2136 | - | 1e-118 | 77.44% (266) | pyridoxamine 5'-phosphate oxidase family protein |
| M. ulcerans Agy99 | MUL_5012 | - | 1e-08 | 25.78% (256) | hypothetical protein MUL_5012 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5737|M.vanbaalenii_PYR-1 -MTSAGSTRDHGDPGDAPSVPPPLTDPADTTRPSAAEEARTIAASTNAGT
MSMEG_6519|M.smegmatis_MC2_155 -----MAVRDHGDPGDAPSVPPPLTPVADVVRPSAAEEARTIAASTNVGT
Mflv_1085|M.gilvum_PYR-GCK -MTTAGPTRDHGDPGDAPTIPPPLSEPANPARPSAAEEARTIAASTNSGT
TH_2136|M.thermoresistible__bu -----VTVRDHGDPGDAPTIPPPLQPPRNPARPSAAEEARTIVASTNTAT
MAB_1906|M.abscessus_ATCC_1997 -----MVSRDHGDPGDAPTIAPPLADVANPARPSAAEEARTVAASTNTAT
Mb3869|M.bovis_AF2122/97 -----MPPLTSLAPTTAERIRSACARAGG-ALLVVEREDPVPVPIHHLLY
Rv3839|M.tuberculosis_H37Rv -----MPPLTSLAPTTAERIRSACARAGG-ALLVVEREDPVPVPIHHLLY
MMAR_5391|M.marinum_M MKEFVMLPLTNPAPTTAERIRSACARAGG-ALLAVERDGPVATPIHHLMP
MUL_5012|M.ulcerans_Agy99 ----MMLPLTSPAPTTAERIRSACARAGG-ALLAVERDGPVATPIHHLMP
* * : .. . . . .: . .. :
Mvan_5737|M.vanbaalenii_PYR-1 LATLTADGDPWASFVTYGLLDGAPVLCVSNLAEHGRNLATDPRASIAIVA
MSMEG_6519|M.smegmatis_MC2_155 LATLTTEGDPWASFVTYGLLGGAPVLCVSDMAEHGRNLAHDPRASIAIVA
Mflv_1085|M.gilvum_PYR-GCK LASLTAAGDPWASFVTYGLLGGAPVLCVSNLAEHGRNLAGDPRASIAIVA
TH_2136|M.thermoresistible__bu LATLTADGDPWASFVTYGDLDGAPVLCVSDLAEHGRNLDADPRASIAIVA
MAB_1906|M.abscessus_ATCC_1997 LASLSADGAPWASLVTYGLLGGAPVLCVSQMAEHGRNLVRDARASVSIVA
Mb3869|M.bovis_AF2122/97 DGSFAVAVPVDR-GEVSG------SQALLELTDYAPLPVREPVRSLVWIR
Rv3839|M.tuberculosis_H37Rv DGSFAVAVPVDR-GEVSG------SQALLELTDYAPLPVREPVRSLVWIR
MMAR_5391|M.marinum_M DGSFAVAVPIEHPGAGTGDPGQPPSQALLELTDYAPLPVREPVRSLVWIR
MUL_5012|M.ulcerans_Agy99 DGTFAVAVPIEHPGAGAGDPGQPPSQAFLELTDYTPLPVREPVRSLVWIR
.:::. * .. ::::: :. *: :
Mvan_5737|M.vanbaalenii_PYR-1 PTAET-----DPLASARVTLAGRVEAPEGAERAAAREAHLSAVAAAKYYI
MSMEG_6519|M.smegmatis_MC2_155 PSAES-----DPLASARVTLAGVAERPEGDELAAARAAHLDAVAAAKYYI
Mflv_1085|M.gilvum_PYR-GCK PAMVSNPSATDPLANARITLAGHVEAPTGTERDAAREAHLAAVPAARYYI
TH_2136|M.thermoresistible__bu PDDAG--AQTDPLARARVTLAGVAERPTGAELTAAREAHLNAVAAARFYI
MAB_1906|M.abscessus_ATCC_1997 PNPPQ-----DPLANTRITLAGKVRRPNEDELPAARAAHVAGVPAARFYI
Mb3869|M.bovis_AF2122/97 ----------GCLHQIPPAELVETLDLIATDNPNPALLQVETPRSGPADA
Rv3839|M.tuberculosis_H37Rv ----------GCLHQIPPAELVETLDLIATDNPNPALLQVETPRPGPADA
MMAR_5391|M.marinum_M ----------GRLHPVPADMIGATLDLIATENPNPALLQVQTPRSAPAHG
MUL_5012|M.ulcerans_Agy99 ----------GRLRPVPADMIGAALDLIATENPNPALLQVQTPRSAPAHG
. * . : . :: ..
Mvan_5737|M.vanbaalenii_PYR-1 DYSDFSLWLLRVSRVRWVGGYGRMDSTSGADYTAAEPDPVTPRAAGAIAH
MSMEG_6519|M.smegmatis_MC2_155 DYSDFSVWVLRVQRVRWVGGYGRMDSTTGEAYAAAEADPVTPRAAGAIAH
Mflv_1085|M.gilvum_PYR-GCK DYSDFTLWVLRVSRVRWVGGYGRMDSATGEAYAAAEPDPVAPASAGAVAH
TH_2136|M.thermoresistible__bu DYSDFTVWLLRVHRVRWVGGYGRMDSATGADYAAAEPDPVRPRAARAVAH
MAB_1906|M.abscessus_ATCC_1997 DYSDFSVWILDVERVRWVGGYGRMDSASGAEYHSATPDPVSPEAARAIKH
Mb3869|M.bovis_AF2122/97 AETRYTMQRLEIESVVVTDATG-AEPVTVADLLAARPDPFCEIESTLLWH
Rv3839|M.tuberculosis_H37Rv AETRYTMQRLEIESVVVTDATG-AEPVTVADLLAARPDPFCEIESTLLWH
MMAR_5391|M.marinum_M AEIRYALLRLEIESVVVTDATG-AEPISVVDLLAARPDPFCEIESSLLRH
MUL_5012|M.ulcerans_Agy99 AEIRYALMRLEIESVVVTDSTG-AEPISVVDLLAARPDPFCEIESSLLRH
::: * : * ... * :. : :* .**. : : *
Mvan_5737|M.vanbaalenii_PYR-1 LNADHADSLAAMARTLGGYPDTRSATCTGVDRYGLDLRLSTERGMAYTRI
MSMEG_6519|M.smegmatis_MC2_155 LNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAYTRV
Mflv_1085|M.gilvum_PYR-GCK LNDDHADSLAAMARALGGYPDTVSATCTGADRYGLDLRVDTERGMAYTRI
TH_2136|M.thermoresistible__bu LNDDHADALTAMARVLGGYPDTRSAVCTGADRYGLDLRVDTERGVAHTRV
MAB_1906|M.abscessus_ATCC_1997 LNDDHGQALLAMAQRLGGYPDATEARCEGADRYGLDIRVSTPRGWSVTRV
Mb3869|M.bovis_AF2122/97 LATAHDDVVARLVSRLPAPLRRGQIRPLGLDRYGVRFRIEARDGDRDIRL
Rv3839|M.tuberculosis_H37Rv LATAHDDVVARLVSRLPAPLRRGQIRPLGLDRYGVRFRIEARDGDRDIRL
MMAR_5391|M.marinum_M LTTDHQDVVARLVSRLPAPLRRGEVRPLGLDRYGVRFRIESNDGDRDIRL
MUL_5012|M.ulcerans_Agy99 LTTDHQDVVARLVSRLPAPLRRGEVRPLGLDRYGVRFRIESNDGDRDIRL
* * : : :. * . . * ****: :*: : * *:
Mvan_5737|M.vanbaalenii_PYR-1 GYARPIDSIDELRSAAAELAQRARNT------
MSMEG_6519|M.smegmatis_MC2_155 GYAAPISSFDQLRAATVELAQRAKQS------
Mflv_1085|M.gilvum_PYR-GCK GYAAPLDSIDQLRSAAVELTRRARGDN-----
TH_2136|M.thermoresistible__bu GYPAPLRSIDELRSAAVELTRMAREGA-----
MAB_1906|M.abscessus_ATCC_1997 GYAEPIDSIEQLRGATVHLARLADPRA-----
Mb3869|M.bovis_AF2122/97 PFHKPVDDMTGLSQAIRVLMGCPFRNGLRARR
Rv3839|M.tuberculosis_H37Rv PFHKPVDDMTGLSQAIRVLMGCPFRNGLRARR
MMAR_5391|M.marinum_M PFHRPVDDMHGLRQAIRVLLGCPFGNGLRARR
MUL_5012|M.ulcerans_Agy99 PFHRPVDDMHGLRQAIRVLLGCPFGNGLRAGR
: *: .: * * * .