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M. smegmatis MC2 155 MSMEG_6519 (-)

VAVRDHGDPGDAPSVPPPLTPVADVVRPSAAEEARTIAASTNVGTLATLTTEGDPWASFVTYGLLGGAPV
LCVSDMAEHGRNLAHDPRASIAIVAPSAESDPLASARVTLAGVAERPEGDELAAARAAHLDAVAAAKYYI
DYSDFSVWVLRVQRVRWVGGYGRMDSTTGEAYAAAEADPVTPRAAGAIAHLNADHADSLLAMARNLGGYP
DTGEAVCTGADRYGLDLRVTTERGVAYTRVGYAAPISSFDQLRAATVELAQRAKQS

Operon Prediction Model: Genebank

Paralogs

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_6519	-	-	100% (266)	pyridoxamine 5'-phosphate oxidase family protein
M. smegmatis MC2 155	MSMEG_6419	-	3e-06	25.41% (244)	hypothetical protein MSMEG_6419
M. smegmatis MC2 155	MSMEG_6576	-	2e-05	32.65% (98)	pyridoxamine 5'-phosphate oxidase family protein

Closest Orthologs (e-value cutoff: 1e-4)

species	id	gene	e-value	identity (len)	annotation
M. bovis AF2122 / 97	-	-	-	-	-
M. gilvum PYR-GCK	Mflv_1085	-	1e-115	76.69% (266)	pyridoxamine 5'-phosphate oxidase-related, FMN-binding
M. tuberculosis H37Rv	Rv1155	-	0.0001	28.81% (118)	hypothetical protein Rv1155
M. leprae Br4923	-	-	-	-	-
M. abscessus ATCC 19977	MAB_1906	-	1e-102	68.85% (260)	pyridoxamine 5'-phosphate oxidase-related
M. marinum M	-	-	-	-	-
M. avium 104	-	-	-	-	-
M. thermoresistible (build 8)	TH_2136	-	1e-115	76.49% (268)	pyridoxamine 5'-phosphate oxidase family protein
M. ulcerans Agy99	MUL_5012	-	6e-05	29.17% (96)	hypothetical protein MUL_5012
M. vanbaalenii PYR-1	Mvan_5737	-	1e-123	81.13% (265)	pyridoxamine 5'-phosphate oxidase-related, FMN-binding

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6519|M.smegmatis_MC2_155      ----MAVRDHGDPGDAPSVPPPLTPV--ADVVRPSAAEEARTIAASTNVG
Mvan_5737|M.vanbaalenii_PYR-1       MTSAGSTRDHGDPGDAPSVPPPLTDP--ADTTRPSAAEEARTIAASTNAG
Mflv_1085|M.gilvum_PYR-GCK          MTTAGPTRDHGDPGDAPTIPPPLSEP--ANPARPSAAEEARTIAASTNSG
TH_2136|M.thermoresistible__bu      ----VTVRDHGDPGDAPTIPPPLQPP--RNPARPSAAEEARTIVASTNTA
MAB_1906|M.abscessus_ATCC_1997      ----MVSRDHGDPGDAPTIAPPLADV--ANPARPSAAEEARTVAASTNTA
Rv1155|M.tuberculosis_H37Rv         ------------------------------MARQVFDDKLLAVISGNSIG
MUL_5012|M.ulcerans_Agy99           ---MMLPLTSPAPTTAERIRSACARAGGALLAVERDGPVATPIHHLMPDG
                                                                   .         .:      .

MSMEG_6519|M.smegmatis_MC2_155      TLATLTTEGDPWASFVTYGLLGGAPVLCVSDMAEHG--RNLAHDPRASIA
Mvan_5737|M.vanbaalenii_PYR-1       TLATLTADGDPWASFVTYGLLDGAPVLCVSNLAEHG--RNLATDPRASIA
Mflv_1085|M.gilvum_PYR-GCK          TLASLTAAGDPWASFVTYGLLGGAPVLCVSNLAEHG--RNLAGDPRASIA
TH_2136|M.thermoresistible__bu      TLATLTADGDPWASFVTYGDLDGAPVLCVSDLAEHG--RNLDADPRASIA
MAB_1906|M.abscessus_ATCC_1997      TLASLSADGAPWASLVTYGLLGGAPVLCVSQMAEHG--RNLVRDARASVS
Rv1155|M.tuberculosis_H37Rv         VLATIKHDGRPQLSNVQYHFDPRKLLIQVSIAEPRAKTRNLRRDPRASIL
MUL_5012|M.ulcerans_Agy99           TFAVAVPIEHPGAGAGDPGQPPSQAFLELTDYTPLP-----VREPVRSLV
                                    .:*       *  .           .: ::             :.  *: 

MSMEG_6519|M.smegmatis_MC2_155      IVAPSAES-----DPLASARVTLAGVAERPEGDELAAARAAHLDAVAAAK
Mvan_5737|M.vanbaalenii_PYR-1       IVAPTAET-----DPLASARVTLAGRVEAPEGAERAAAREAHLSAVAAAK
Mflv_1085|M.gilvum_PYR-GCK          IVAPAMVSNPSATDPLANARITLAGHVEAPTGTERDAAREAHLAAVPAAR
TH_2136|M.thermoresistible__bu      IVAPDDAG--AQTDPLARARVTLAGVAERPTGAELTAAREAHLNAVAAAR
MAB_1906|M.abscessus_ATCC_1997      IVAPNPPQ-----DPLANTRITLAGKVRRPNEDELPAARAAHVAGVPAAR
Rv1155|M.tuberculosis_H37Rv         VDADDGWS------------------------------------------
MUL_5012|M.ulcerans_Agy99           WIRGRLRP----------VPADMIGAALDLIATENPNPALLQVQTPRSAP
                                                                                      

MSMEG_6519|M.smegmatis_MC2_155      YYIDYSDFSVWVLRVQRVRWVGGYGRMDSTTGEAYAAAEADPVTPRAAGA
Mvan_5737|M.vanbaalenii_PYR-1       YYIDYSDFSLWLLRVSRVRWVGGYGRMDSTSGADYTAAEPDPVTPRAAGA
Mflv_1085|M.gilvum_PYR-GCK          YYIDYSDFTLWVLRVSRVRWVGGYGRMDSATGEAYAAAEPDPVAPASAGA
TH_2136|M.thermoresistible__bu      FYIDYSDFTVWLLRVHRVRWVGGYGRMDSATGADYAAAEPDPVRPRAARA
MAB_1906|M.abscessus_ATCC_1997      FYIDYSDFSVWILDVERVRWVGGYGRMDSASGAEYHSATPDPVSPEAARA
Rv1155|M.tuberculosis_H37Rv         -----------------------YAVAEGTAQLTPPAAAPD---------
MUL_5012|M.ulcerans_Agy99           AHGAEIRYALMRLEIESVVVTDSTGAEP-ISVVDLLAARPDPFCEIESSL
                                                            .     :     :* .*         

MSMEG_6519|M.smegmatis_MC2_155      IAHLNADHADSLLAMARNLGGYPDTGEAVCTGADRYGLDLRVTTERGVAY
Mvan_5737|M.vanbaalenii_PYR-1       IAHLNADHADSLAAMARTLGGYPDTRSATCTGVDRYGLDLRLSTERGMAY
Mflv_1085|M.gilvum_PYR-GCK          VAHLNDDHADSLAAMARALGGYPDTVSATCTGADRYGLDLRVDTERGMAY
TH_2136|M.thermoresistible__bu      VAHLNDDHADALTAMARVLGGYPDTRSAVCTGADRYGLDLRVDTERGVAH
MAB_1906|M.abscessus_ATCC_1997      IKHLNDDHGQALLAMAQRLGGYPDATEARCEGADRYGLDIRVSTPRGWSV
Rv1155|M.tuberculosis_H37Rv         -----DDTVEALIALYRNIAG---------EHSDWDDYRQAMVTDR----
MUL_5012|M.ulcerans_Agy99           LRHLTTDHQDVVARLVSRLPAPLRRGEVRPLGLDRYGVRFRIESNDGDRD
                                          *  : :  :   : .            *  .    : :      

MSMEG_6519|M.smegmatis_MC2_155      TRVGYAAPISSFDQLRAATVELAQRAKQS------
Mvan_5737|M.vanbaalenii_PYR-1       TRIGYARPIDSIDELRSAAAELAQRARNT------
Mflv_1085|M.gilvum_PYR-GCK          TRIGYAAPLDSIDQLRSAAVELTRRARGDN-----
TH_2136|M.thermoresistible__bu      TRVGYPAPLRSIDELRSAAVELTRMAREGA-----
MAB_1906|M.abscessus_ATCC_1997      TRVGYAEPIDSIEQLRGATVHLARLADPRA-----
Rv1155|M.tuberculosis_H37Rv         -RVLLTLPISHVYGLPPGMR---------------
MUL_5012|M.ulcerans_Agy99           IRLPFHRPVDDMHGLRQAIRVLLGCPFGNGLRAGR
                                     *:    *:  .  *  .