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DDTDVPQASIGDVPVDFDETVVLLDVREDDEWQRGHAPGAQHIPMGDVPARLAEIDTEAQLFVVCHAGGR SQRVAQYLARNGYDPINVAGGMLAWAGAGRPVVTDGGDSGAI*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5669 | - | - | 100% (113) | rhodanese domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4028 | - | 9e-21 | 48.35% (91) | rhodanese domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_4023 | - | 2e-08 | 39.19% (74) | beta-lactamase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0332 | - | 6e-08 | 36.90% (84) | ArsR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1138 | - | 2e-50 | 77.88% (113) | rhodanese domain-containing protein |
| M. tuberculosis H37Rv | Rv0324 | - | 5e-08 | 36.90% (84) | ArsR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00817 | moeZ | 1e-07 | 31.11% (90) | molybdopterin biosynthesis-like protein MoeZ |
| M. abscessus ATCC 19977 | MAB_0121 | - | 1e-33 | 60.40% (101) | rhodanese-like protein |
| M. marinum M | MMAR_1352 | moeB1 | 4e-08 | 32.22% (90) | molybdenum cofactor biosynthesis protein MoeB1 |
| M. avium 104 | MAV_4153 | - | 1e-06 | 30.00% (90) | molybdopterin biosynthesis-like protein MoeZ |
| M. smegmatis MC2 155 | MSMEG_6425 | - | 3e-48 | 75.22% (113) | rhodanese-like domain-containing protein |
| M. thermoresistible (build 8) | TH_1234 | - | 3e-09 | 40.26% (77) | metallo-beta-lactamase family protein |
| M. ulcerans Agy99 | MUL_2527 | moeB1 | 3e-07 | 31.11% (90) | molybdopterin biosynthesis-like protein MoeZ |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0332|M.bovis_AF2122/97 --------------------------------------------------
Rv0324|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5669|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1234|M.thermoresistible__bu MKFIQYYLDCLSHASYLIADDKTGRAVVVDPQRDVAEYLSDAEKYGYTIE
MMAR_1352|M.marinum_M -----------------------MSTTALPPLVAPAATLSREEVARYSRH
MUL_2527|M.ulcerans_Agy99 -----------------------MSTTALPPLVAPAATLSREEVARYSRH
MLBr_00817|M.leprae_Br4923 ---------------------MSTSSTSLPPLVEPAGQLSRDEVIRYSRH
MAV_4153|M.avium_104 ------------------------MSTPLPPLVAPADQLTADEMARYSRQ
Mb0332|M.bovis_AF2122/97 --------------------------------------------------
Rv0324|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5669|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1234|M.thermoresistible__bu LVIETHFHADFLSGHLELAEATGAKIVYSSVAETEFESMGVADGERYSLG
MMAR_1352|M.marinum_M LIIPDLG----------------------VDGQKRLKNARVLVIGAGGLG
MUL_2527|M.ulcerans_Agy99 LIIPDLG----------------------VDGQKRLKNARVLVIGAGGLG
MLBr_00817|M.leprae_Br4923 LIIPDIG----------------------VDGQMRLKSARVLVIGAGGLG
MAV_4153|M.avium_104 LIIPGLG----------------------VDGQKRLKNARVLVIGAGGLG
Mb0332|M.bovis_AF2122/97 --------------------------------------------------
Rv0324|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5669|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1234|M.thermoresistible__bu DVTLEFLHTPGHTPESLSIVVYEHADDEIPYGVLTGDTLFIGDVGRPDLL
MMAR_1352|M.marinum_M SPTLLYLAAAGVG--TIGIVDFDVVDESNLQRQIIHG------------V
MUL_2527|M.ulcerans_Agy99 SPTLLYLAAAGVG--TIGIVDFDVVDESNLQRQIIHG------------V
MLBr_00817|M.leprae_Br4923 APVLLYLAAAGVG--TIGIIDFDVVDESNLQRQIIHG------------V
MAV_4153|M.avium_104 APTLLYLAAAGVG--TIGIVEFDAVEESNLQRQIIHG------------V
Mb0332|M.bovis_AF2122/97 --------------------------------------------------
Rv0324|M.tuberculosis_H37Rv --------------------------------------------------
Mvan_5669|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1234|M.thermoresistible__bu ASIGYTREELADKLYDSLHHKLMTLPDATRVYPAHGAGSACGKNLSTELW
MMAR_1352|M.marinum_M ADVGRSKAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGT
MUL_2527|M.ulcerans_Agy99 ADVGRSKAQSARDSIVAINPLIEVRLHEFRLESDNAVDLFGHYDLIIDGT
MLBr_00817|M.leprae_Br4923 ADVGRSKAQSARDSIVAINPLVQVRLHEFRLESSNVVNLFKQYDLIVDGT
MAV_4153|M.avium_104 ADVGRSKAASARDSIAAINPLVDVRLHEFRLDASNAVELFGHYDLIVDGT
Mb0332|M.bovis_AF2122/97 --------------------------------------------MAGQSD
Rv0324|M.tuberculosis_H37Rv --------------------------------------------MAGQSD
Mvan_5669|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1234|M.thermoresistible__bu STIGEQRETNYALRAPDKATFIELVTEGQPPAPGYFVYDAILNRKNRGLL
MMAR_1352|M.marinum_M DNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGL
MUL_2527|M.ulcerans_Agy99 DNFATRYLVNDAAVLAGKPYVWGSIYRFEGQVSVFWEDAP-----GGLGL
MLBr_00817|M.leprae_Br4923 DNFATRYLINDAAVLAKKPYVWGSLYRFEGQVSVFWEDAP-----DGLGL
MAV_4153|M.avium_104 DNFATRYLINDAAVLAGKPYVWGSIYRFEGQASVCWEDAP-----DGRGL
Mb0332|M.bovis_AF2122/97 RKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTAS
Rv0324|M.tuberculosis_H37Rv RKAALLDQVARVGKALANGRRLQILDLLAQGERAVEAIATATGMNLTTAS
Mvan_5669|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1138|M.gilvum_PYR-GCK --------------------------------------------------
MSMEG_6425|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0121|M.abscessus_ATCC_1997 --------------------------------------------------
TH_1234|M.thermoresistible__bu DETALPPVLSYDEMLAAVERGAVLVDGRSPEEFAQGHLRGAINIGLDGRY
MMAR_1352|M.marinum_M NYRDLYPEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIG--E
MUL_2527|M.ulcerans_Agy99 NYRDLYPEPPPPGMVPSCAEGGVLGIICASIASVMGTEAVKLITGIG--E
MLBr_00817|M.leprae_Br4923 NYRDLYLEPPPPGMVPSCAEGGVLGIVCASIASVMGTEAIKLITGIG--A
MAV_4153|M.avium_104 NYRDLYPEPPPPGAVPSCAEGGVLGVVCAAIASVMSTEVIKLITGIG--E
Mb0332|M.bovis_AF2122/97 ANLQALKSGGLVEARREGTRQYYRIAGEDVARLFALVQVVADEHLADVAV
Rv0324|M.tuberculosis_H37Rv ANLQALKSGGLVEARREGTRQYYRIAGEDVARLFALVQVVADEHLADVAV
Mvan_5669|M.vanbaalenii_PYR-1 -----------------------------------------MDDT---DV
Mflv_1138|M.gilvum_PYR-GCK -----------------------------------------MDDP---DV
MSMEG_6425|M.smegmatis_MC2_155 -----------------------------------------MDDV---EV
MAB_0121|M.abscessus_ATCC_1997 -----------------------------------------MSFPTGDDV
TH_1234|M.thermoresistible__bu AEFAGSVLPADVDIVLFTEPGDELEAKNRLARIGFDRVIGHLDRPFEVMM
MMAR_1352|M.marinum_M TLLGRLMIYDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVS
MUL_2527|M.ulcerans_Agy99 TLLGRLMIYDALEMTYRTIRIRKDP---ATPKITALIDYEQFCG---VVS
MLBr_00817|M.leprae_Br4923 PLLGRLMIYNALEMSYRRIRIHKDP---SRPKITELTDYQQFCG---VVS
MAV_4153|M.avium_104 SLLGRLMIYDALEMSYRTIAIRRDPCDASRPAITTLVDYEQLCGAAPAAS
Mb0332|M.bovis_AF2122/97 AAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAINIP
Rv0324|M.tuberculosis_H37Rv AAADVLGSPEDAITRAELLRRREAGEVTLVDVRPHEEYQAGHIPGAINIP
Mvan_5669|M.vanbaalenii_PYR-1 PQASIGDVPVDFDET-----------VVLLDVREDDEWQRGHAPGAQHIP
Mflv_1138|M.gilvum_PYR-GCK PQAAISDVPSTFGDG-----------VVLLDVREDDEWQRGHAPQARHIP
MSMEG_6425|M.smegmatis_MC2_155 AKADISAVPTTFDQS-----------VVLLDVREDDEWQRGHVAGAQHIP
MAB_0121|M.abscessus_ATCC_1997 PQVGIDEISAALSLG-----------VKLLDVREDDEWAAGHIEGAQHIP
TH_1234|M.thermoresistible__bu AHPDRVQVASRLTVKAFDQRAAELPDLQIVDVRNPGEVALGAIPGAIAIP
MMAR_1352|M.marinum_M DDVARAASDSTITPQELRAMIDSGKKLALIDVREQVEWDIVHIDGAQLIP
MUL_2527|M.ulcerans_Agy99 DDVARAASDSTITPQELRAMINSGKKLALIDVREQVEWDIVHIDGAQLIP
MLBr_00817|M.leprae_Br4923 DDAAQVATGSIVTPRELRELLDSGKKLALIDVREPVEWDIVHIDGAQLIP
MAV_4153|M.avium_104 TDAATGGAEAAITPRQLRELLDSGAKLALIDVREPVEFDIVHLDGAQLIP
: ::*** * * **
Mb0332|M.bovis_AF2122/97 IAELADR--LAELAGDRDIVAYCRGAYCVMAPDAVRIARDAGREVKRLDD
Rv0324|M.tuberculosis_H37Rv IAELADR--LAELTGDRDIVAYCRGAYCVMAPDAVRIARDAGREVKRLDD
Mvan_5669|M.vanbaalenii_PYR-1 MGDVPAR--LAEIDTEAQLFVVCHAGGRSQR-VAQYLARNGYDPIN-VAG
Mflv_1138|M.gilvum_PYR-GCK MGDVPAR--LAELDADAELYVVCHVGGRSQR-VAQYLARNGFRPVN-VTG
MSMEG_6425|M.smegmatis_MC2_155 MGEVPAR--MAEIDPDAELYVICHAGGRSLR-VANYLARNGYTPIN-VEG
MAB_0121|M.abscessus_ATCC_1997 LGDVPSR--MDELDPDAPLWVICHAGGRSQR-AAAYLNRNGFDVSN-VSG
TH_1234|M.thermoresistible__bu VGQLPDR--LTELDPTRPTVVYCAGGYRSSV-AASLLRRSGFTDVSDILG
MMAR_1352|M.marinum_M KSLISTGEGLAKLPQDRTTVLYCKTGVRSAE-ALAALKKAGFADAVHLQG
MUL_2527|M.ulcerans_Agy99 KSLISTGEGLAKLPQDRTTVLYCKTGVRSAE-ALAALKKAGFADAAHLQG
MLBr_00817|M.leprae_Br4923 RSLINSGEGLAKLPQDRMSVLYCKTGVRSAE-TLATVKKAGFSDAVHLQG
MAV_4153|M.avium_104 QSSINSGEGLAKLPADRMPVLYCKTGVRSAQ-ALAVVRQAGFSDAVHLQG
. : : :: * . : : . : .
Mb0332|M.bovis_AF2122/97 GMLEWRLAGLPVDEGAPVGHGD
Rv0324|M.tuberculosis_H37Rv GMLEWRLAGLPVDEGAPVGHGD
Mvan_5669|M.vanbaalenii_PYR-1 GMLAWAGAGRPVVTDGGDSGAI
Mflv_1138|M.gilvum_PYR-GCK GMLAWAGAGRPVVTDAGNVGTV
MSMEG_6425|M.smegmatis_MC2_155 GMLAWAGAGRPMVTDDGSAGAI
MAB_0121|M.abscessus_ATCC_1997 GMLAWVQAGKPTIS--------
TH_1234|M.thermoresistible__bu GYGAWVDARQVA----------
MMAR_1352|M.marinum_M GIVAWANQMQPDMVMY------
MUL_2527|M.ulcerans_Agy99 GIVAWANQMQPDMVMY------
MLBr_00817|M.leprae_Br4923 GIVAWAKQVQPDMVIY------
MAV_4153|M.avium_104 GIVAWAQQMQPDMILY------
* *