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SERCPTVLDVCTRVVYLGTNDRVVTGRSMDWKVEIGTNLWVLPRGIRRAGQAGPDSLEWTAKYGSVVATA YDICSTDGVNEAGLAANLLWLAESQYPADDAGGPAVALSLWAQYVLDNFATVAEAVAALTANPLRVATAE VPGQQRMATLHLAMSDASGDSAIVEYIDGRQTIHHDRSHQVMTNSPTFDKQLAITEYWEEIGGTVMLPGT NRAADRFVRAAFYINAVPKCDDPVLAVAAVFSVVRNVSTPYGIATSDEPNISSTRWRTVVDHKSLRYFFE SALSPNTFWVDLKNLDFSVDAPVRRLELGEGEKTIYAGDTSAQFQPAEPFAFLAVP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5516 | - | - | 100% (337) | choloylglycine hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1302 | - | 1e-160 | 82.52% (326) | choloylglycine hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2570 | - | 2e-91 | 49.54% (327) | hydrolase/amidase |
| M. avium 104 | - | - | - | - | - |
| M. smegmatis MC2 155 | MSMEG_5454 | - | 2e-46 | 35.67% (328) | choloylglycine hydrolase, putative |
| M. thermoresistible (build 8) | TH_3250 | - | 1e-169 | 85.93% (327) | PUTATIVE Choloylglycine hydrolase |
| M. ulcerans Agy99 | MUL_3191 | - | 9e-91 | 49.24% (327) | hydrolase/amidase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2570|M.marinum_M ----------MCTRILYKTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR
MUL_3191|M.ulcerans_Agy99 ----------MCTRILYRTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR
Mvan_5516|M.vanbaalenii_PYR-1 MSERCPTVLDVCTRVVYLGTNDRVVTGRSMDWK-VEIGTNLWVLPRGIRR
TH_3250|M.thermoresistible__bu ----------MCTRVVYLGTSDRVITGRSMDWK-FEIATNLWALPRGINR
Mflv_1302|M.gilvum_PYR-GCK ----------MCTRVVYLGDEDRVVTGRSMDWK-VEIGTNLWALPRGVAR
MSMEG_5454|M.smegmatis_MC2_155 ----------MCTRVLWNSNKLAVLSGRSMDWP-ESTEPLIVAFASGRDR
:***::: ::**.*** . . .:. * *
MMAR_2570|M.marinum_M DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL
MUL_3191|M.ulcerans_Agy99 DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL
Mvan_5516|M.vanbaalenii_PYR-1 AGQAGP-------DSLEWTAKYGSVVATAYDICSTDGVNEAGLAANLLWL
TH_3250|M.thermoresistible__bu TGQAGP-------DSVEWTAKYGSVVATGYDICTTDGVNEAGLAVNLLWL
Mflv_1302|M.gilvum_PYR-GCK TGQAGP-------DSVEWTAKYGSVVATGYDISTTDGLNEAGLAANLLWL
MSMEG_5454|M.smegmatis_MC2_155 DGGLLAGHPVIPENPLRWTSRHASLATTVYGLGTVDGINAAGLGVHALYL
* . ..: **:::.*: : *.: : **:* **: : *:*
MMAR_2570|M.marinum_M TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVEAMSADPMTVVSAD
MUL_3191|M.ulcerans_Agy99 TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVQAMSADPMTVVSAD
Mvan_5516|M.vanbaalenii_PYR-1 AESQYPADDA-GGPAVALSLWAQYVLDNFATVAEAVAALTANPLRVATAE
TH_3250|M.thermoresistible__bu AESQYPADGA-GGPAISLALWGQYVLDNFATVAEAVTALAATPLRVATAE
Mflv_1302|M.gilvum_PYR-GCK AESQYPANTG-DRPALAISLWAQYMLDNFATVAEAVAALTATPLRVVTAE
MSMEG_5454|M.smegmatis_MC2_155 KSTDVGPRNP-DLPGLHTGLWAQYLLDQAATVEEALALMQDVQLVMVG--
.:: . * : . * **:**: .** **: : : :.
MMAR_2570|M.marinum_M AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ
MUL_3191|M.ulcerans_Agy99 AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ
Mvan_5516|M.vanbaalenii_PYR-1 VPGQQRMATLHLAMSDASGDSAIVEYIDGRQTIHHDRSHQVMTNSPTFDK
TH_3250|M.thermoresistible__bu VPGEQRMATLHLAMSDATGDSAVVEYIDGRQTVHHGRQYQVMTNSPTFDK
Mflv_1302|M.gilvum_PYR-GCK VPGQERMATVHLALSDATGDSAIVEYIDGEQVIHHGRQYQVMTNSPTFDK
MSMEG_5454|M.smegmatis_MC2_155 --ARGREATLHLAIEDATGDSAILELEAGKLAVHHGRQFTLMTNDPTYDE
. * *::*:*:.** ****:.* .. .:**.*.. ::**.*.:::
MMAR_2570|M.marinum_M QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA
MUL_3191|M.ulcerans_Agy99 QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA
Mvan_5516|M.vanbaalenii_PYR-1 QLAITEYWEEIGGT--VMLPGTNRAADRFVRAAFYINAVPKCDDPVLAVA
TH_3250|M.thermoresistible__bu QLAITEYWEQIGGT--VMLPGTNRAADRFVRASFYINAVPKSDDPQLSVA
Mflv_1302|M.gilvum_PYR-GCK QLAITEYWKEIGGT--VMLPGTNRAADRFVRASFYIDAVPKTDDPLLAAA
MSMEG_5454|M.smegmatis_MC2_155 QLALLAKQDFSHPTRELPLPGNVNPVDRFQRAAYYSALLPEPTGIRQGVA
***: . ***. ..*** **:: *: . ..*
MMAR_2570|M.marinum_M AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI
MUL_3191|M.ulcerans_Agy99 AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI
Mvan_5516|M.vanbaalenii_PYR-1 AVFSVVRNVSTPYGIATSDEPNISSTRWRTVVDHKSLRYFFESALSPNTF
TH_3250|M.thermoresistible__bu AVMSVMRNVSTPYGIATSDEPNISSTRWRTVVDHKAQRYFFESALSPNTF
Mflv_1302|M.gilvum_PYR-GCK TVFSVVRNASVPYGIATADEPNISSTRWRTVIDHKSLRYFFESALSPNTF
MSMEG_5454|M.smegmatis_MC2_155 SVMAIMRNVSVPFGAPYG-EFGVYNTEYRTVSDLTHKLYFFELSTSPSVI
:*:: :*. ..* * . : .: .* :*:* * *:*: .*..:
MMAR_2570|M.marinum_M WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKFEPAAPFHFLAPSPR
MUL_3191|M.ulcerans_Agy99 WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKVEPAAPFHFLAPSPR
Mvan_5516|M.vanbaalenii_PYR-1 WVDLKNLDFSVDAPVRRLELGEGEKTIYAGDTSAQFQPAEPFAFLAVP--
TH_3250|M.thermoresistible__bu WVELQNLDFSEDAPVRRLSLGEGEKTIYAGDASARFEPADPFTFLSVPA-
Mflv_1302|M.gilvum_PYR-GCK WVELKNLDLSAGASALRLQLGEGEKTVYAGDASGRFEPAEPFAFLGLA--
MSMEG_5454|M.smegmatis_MC2_155 WVEFDHLELPAAGQAVAIDP---YDETLTGNVTDRFTPRE-LAF------
**::.::::. . : . *:.: :. * : *