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MCTRVLWNSNKLAVLSGRSMDWPESTEPLIVAFASGRDRDGGLLAGHPVIPENPLRWTSRHASLATTVYG LGTVDGINAAGLGVHALYLKSTDVGPRNPDLPGLHTGLWAQYLLDQAATVEEALALMQDVQLVMVGARGR EATLHLAIEDATGDSAILELEAGKLAVHHGRQFTLMTNDPTYDEQLALLAKQDFSHPTRELPLPGNVNPV DRFQRAAYYSALLPEPTGIRQGVASVMAIMRNVSVPFGAPYGEFGVYNTEYRTVSDLTHKLYFFELSTSP SVIWVEFDHLELPAAGQAVAIDPYDETLTGNVTDRFTPRELAF
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5454 | - | - | 100% (323) | choloylglycine hydrolase, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | - | - | - | - | - |
| M. gilvum PYR-GCK | Mflv_1302 | - | 8e-54 | 38.11% (328) | choloylglycine hydrolase |
| M. tuberculosis H37Rv | - | - | - | - | - |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_2570 | - | 4e-50 | 36.09% (327) | hydrolase/amidase |
| M. avium 104 | - | - | - | - | - |
| M. thermoresistible (build 8) | TH_3250 | - | 3e-52 | 37.50% (328) | PUTATIVE Choloylglycine hydrolase |
| M. ulcerans Agy99 | MUL_3191 | - | 2e-49 | 35.78% (327) | hydrolase/amidase |
| M. vanbaalenii PYR-1 | Mvan_5516 | - | 1e-46 | 35.67% (328) | choloylglycine hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3250|M.thermoresistible__bu ----------MCTRVVYLGTSDRVITGRSMDWK-FEIATNLWALPRGINR
Mvan_5516|M.vanbaalenii_PYR-1 MSERCPTVLDVCTRVVYLGTNDRVVTGRSMDWK-VEIGTNLWVLPRGIRR
Mflv_1302|M.gilvum_PYR-GCK ----------MCTRVVYLGDEDRVVTGRSMDWK-VEIGTNLWALPRGVAR
MMAR_2570|M.marinum_M ----------MCTRILYKTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR
MUL_3191|M.ulcerans_Agy99 ----------MCTRILYRTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR
MSMEG_5454|M.smegmatis_MC2_155 ----------MCTRVLWNSNKLAVLSGRSMDWP-ESTEPLIVAFASGRDR
:***::: ::**.*** . . .:. * *
TH_3250|M.thermoresistible__bu TGQAGP-------DSVEWTAKYGSVVATGYDICTTDGVNEAGLAVNLLWL
Mvan_5516|M.vanbaalenii_PYR-1 AGQAGP-------DSLEWTAKYGSVVATAYDICSTDGVNEAGLAANLLWL
Mflv_1302|M.gilvum_PYR-GCK TGQAGP-------DSVEWTAKYGSVVATGYDISTTDGLNEAGLAANLLWL
MMAR_2570|M.marinum_M DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL
MUL_3191|M.ulcerans_Agy99 DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL
MSMEG_5454|M.smegmatis_MC2_155 DGGLLAGHPVIPENPLRWTSRHASLATTVYGLGTVDGINAAGLGVHALYL
* . ..: **:::.*: : *.: : **:* **: : *:*
TH_3250|M.thermoresistible__bu AESQYPADGA-GGPAISLALWGQYVLDNFATVAEAVTALAATPLRVATAE
Mvan_5516|M.vanbaalenii_PYR-1 AESQYPADDA-GGPAVALSLWAQYVLDNFATVAEAVAALTANPLRVATAE
Mflv_1302|M.gilvum_PYR-GCK AESQYPANTG-DRPALAISLWAQYMLDNFATVAEAVAALTATPLRVVTAE
MMAR_2570|M.marinum_M TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVEAMSADPMTVVSAD
MUL_3191|M.ulcerans_Agy99 TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVQAMSADPMTVVSAD
MSMEG_5454|M.smegmatis_MC2_155 KSTDVGPRNP-DLPGLHTGLWAQYLLDQAATVEEALALMQDVQLVMVG--
.:: . * : . * **:**: .** **: : : :.
TH_3250|M.thermoresistible__bu VPGEQRMATLHLAMSDATGDSAVVEYIDGRQTVHHGRQYQVMTNSPTFDK
Mvan_5516|M.vanbaalenii_PYR-1 VPGQQRMATLHLAMSDASGDSAIVEYIDGRQTIHHDRSHQVMTNSPTFDK
Mflv_1302|M.gilvum_PYR-GCK VPGQERMATVHLALSDATGDSAIVEYIDGEQVIHHGRQYQVMTNSPTFDK
MMAR_2570|M.marinum_M AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ
MUL_3191|M.ulcerans_Agy99 AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ
MSMEG_5454|M.smegmatis_MC2_155 --ARGREATLHLAIEDATGDSAILELEAGKLAVHHGRQFTLMTNDPTYDE
. * *::*:*:.** ****:.* .. .:**.*.. ::**.*.:::
TH_3250|M.thermoresistible__bu QLAITEYWEQIGGT--VMLPGTNRAADRFVRASFYINAVPKSDDPQLSVA
Mvan_5516|M.vanbaalenii_PYR-1 QLAITEYWEEIGGT--VMLPGTNRAADRFVRAAFYINAVPKCDDPVLAVA
Mflv_1302|M.gilvum_PYR-GCK QLAITEYWKEIGGT--VMLPGTNRAADRFVRASFYIDAVPKTDDPLLAAA
MMAR_2570|M.marinum_M QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA
MUL_3191|M.ulcerans_Agy99 QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA
MSMEG_5454|M.smegmatis_MC2_155 QLALLAKQDFSHPTRELPLPGNVNPVDRFQRAAYYSALLPEPTGIRQGVA
***: . ***. ..*** **:: *: . ..*
TH_3250|M.thermoresistible__bu AVMSVMRNVSTPYGIATSDEPNISSTRWRTVVDHKAQRYFFESALSPNTF
Mvan_5516|M.vanbaalenii_PYR-1 AVFSVVRNVSTPYGIATSDEPNISSTRWRTVVDHKSLRYFFESALSPNTF
Mflv_1302|M.gilvum_PYR-GCK TVFSVVRNASVPYGIATADEPNISSTRWRTVIDHKSLRYFFESALSPNTF
MMAR_2570|M.marinum_M AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI
MUL_3191|M.ulcerans_Agy99 AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI
MSMEG_5454|M.smegmatis_MC2_155 SVMAIMRNVSVPFGAPYG-EFGVYNTEYRTVSDLTHKLYFFELSTSPSVI
:*:: :*. ..* * . : .: .* :*:* * *:*: .*..:
TH_3250|M.thermoresistible__bu WVELQNLDFSEDAPVRRLSLGEGEKTIYAGDASARFEPADPFTFLSVPA-
Mvan_5516|M.vanbaalenii_PYR-1 WVDLKNLDFSVDAPVRRLELGEGEKTIYAGDTSAQFQPAEPFAFLAVP--
Mflv_1302|M.gilvum_PYR-GCK WVELKNLDLSAGASALRLQLGEGEKTVYAGDASGRFEPAEPFAFLGLA--
MMAR_2570|M.marinum_M WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKFEPAAPFHFLAPSPR
MUL_3191|M.ulcerans_Agy99 WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKVEPAAPFHFLAPSPR
MSMEG_5454|M.smegmatis_MC2_155 WVEFDHLELPAAGQAVAIDP---YDETLTGNVTDRFTPRE-LAF------
**::.::::. . : . *:.: :. * : *