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MCTRVVYLGDEDRVVTGRSMDWKVEIGTNLWALPRGVARTGQAGPDSVEWTAKYGSVVATGYDISTTDGL NEAGLAANLLWLAESQYPANTGDRPALAISLWAQYMLDNFATVAEAVAALTATPLRVVTAEVPGQERMAT VHLALSDATGDSAIVEYIDGEQVIHHGRQYQVMTNSPTFDKQLAITEYWKEIGGTVMLPGTNRAADRFVR ASFYIDAVPKTDDPLLAAATVFSVVRNASVPYGIATADEPNISSTRWRTVIDHKSLRYFFESALSPNTFW VELKNLDLSAGASALRLQLGEGEKTVYAGDASGRFEPAEPFAFLGLA
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_1302 | - | - | 100% (327) | choloylglycine hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | - | - | - | - | - |
M. tuberculosis H37Rv | - | - | - | - | - |
M. leprae Br4923 | - | - | - | - | - |
M. abscessus ATCC 19977 | - | - | - | - | - |
M. marinum M | MMAR_2570 | - | 3e-91 | 49.69% (326) | hydrolase/amidase |
M. avium 104 | - | - | - | - | - |
M. smegmatis MC2 155 | MSMEG_5454 | - | 1e-53 | 38.11% (328) | choloylglycine hydrolase, putative |
M. thermoresistible (build 8) | TH_3250 | - | 1e-159 | 80.98% (326) | PUTATIVE Choloylglycine hydrolase |
M. ulcerans Agy99 | MUL_3191 | - | 2e-90 | 49.39% (326) | hydrolase/amidase |
M. vanbaalenii PYR-1 | Mvan_5516 | - | 1e-160 | 82.52% (326) | choloylglycine hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment MMAR_2570|M.marinum_M ----------MCTRILYKTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR MUL_3191|M.ulcerans_Agy99 ----------MCTRILYRTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR TH_3250|M.thermoresistible__bu ----------MCTRVVYLGTSDRVITGRSMDWK-FEIATNLWALPRGINR Mvan_5516|M.vanbaalenii_PYR-1 MSERCPTVLDVCTRVVYLGTNDRVVTGRSMDWK-VEIGTNLWVLPRGIRR Mflv_1302|M.gilvum_PYR-GCK ----------MCTRVVYLGDEDRVVTGRSMDWK-VEIGTNLWALPRGVAR MSMEG_5454|M.smegmatis_MC2_155 ----------MCTRVLWNSNKLAVLSGRSMDWP-ESTEPLIVAFASGRDR :***::: ::**.*** . . .:. * * MMAR_2570|M.marinum_M DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL MUL_3191|M.ulcerans_Agy99 DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL TH_3250|M.thermoresistible__bu TGQAGP-------DSVEWTAKYGSVVATGYDICTTDGVNEAGLAVNLLWL Mvan_5516|M.vanbaalenii_PYR-1 AGQAGP-------DSLEWTAKYGSVVATAYDICSTDGVNEAGLAANLLWL Mflv_1302|M.gilvum_PYR-GCK TGQAGP-------DSVEWTAKYGSVVATGYDISTTDGLNEAGLAANLLWL MSMEG_5454|M.smegmatis_MC2_155 DGGLLAGHPVIPENPLRWTSRHASLATTVYGLGTVDGINAAGLGVHALYL * . ..: **:::.*: : *.: : **:* **: : *:* MMAR_2570|M.marinum_M TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVEAMSADPMTVVSAD MUL_3191|M.ulcerans_Agy99 TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVQAMSADPMTVVSAD TH_3250|M.thermoresistible__bu AESQYPADGA-GGPAISLALWGQYVLDNFATVAEAVTALAATPLRVATAE Mvan_5516|M.vanbaalenii_PYR-1 AESQYPADDA-GGPAVALSLWAQYVLDNFATVAEAVAALTANPLRVATAE Mflv_1302|M.gilvum_PYR-GCK AESQYPANTG-DRPALAISLWAQYMLDNFATVAEAVAALTATPLRVVTAE MSMEG_5454|M.smegmatis_MC2_155 KSTDVGPRNP-DLPGLHTGLWAQYLLDQAATVEEALALMQDVQLVMVG-- .:: . * : . * **:**: .** **: : : :. MMAR_2570|M.marinum_M AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ MUL_3191|M.ulcerans_Agy99 AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ TH_3250|M.thermoresistible__bu VPGEQRMATLHLAMSDATGDSAVVEYIDGRQTVHHGRQYQVMTNSPTFDK Mvan_5516|M.vanbaalenii_PYR-1 VPGQQRMATLHLAMSDASGDSAIVEYIDGRQTIHHDRSHQVMTNSPTFDK Mflv_1302|M.gilvum_PYR-GCK VPGQERMATVHLALSDATGDSAIVEYIDGEQVIHHGRQYQVMTNSPTFDK MSMEG_5454|M.smegmatis_MC2_155 --ARGREATLHLAIEDATGDSAILELEAGKLAVHHGRQFTLMTNDPTYDE . * *::*:*:.** ****:.* .. .:**.*.. ::**.*.::: MMAR_2570|M.marinum_M QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA MUL_3191|M.ulcerans_Agy99 QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA TH_3250|M.thermoresistible__bu QLAITEYWEQIGGT--VMLPGTNRAADRFVRASFYINAVPKSDDPQLSVA Mvan_5516|M.vanbaalenii_PYR-1 QLAITEYWEEIGGT--VMLPGTNRAADRFVRAAFYINAVPKCDDPVLAVA Mflv_1302|M.gilvum_PYR-GCK QLAITEYWKEIGGT--VMLPGTNRAADRFVRASFYIDAVPKTDDPLLAAA MSMEG_5454|M.smegmatis_MC2_155 QLALLAKQDFSHPTRELPLPGNVNPVDRFQRAAYYSALLPEPTGIRQGVA ***: . ***. ..*** **:: *: . ..* MMAR_2570|M.marinum_M AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI MUL_3191|M.ulcerans_Agy99 AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI TH_3250|M.thermoresistible__bu AVMSVMRNVSTPYGIATSDEPNISSTRWRTVVDHKAQRYFFESALSPNTF Mvan_5516|M.vanbaalenii_PYR-1 AVFSVVRNVSTPYGIATSDEPNISSTRWRTVVDHKSLRYFFESALSPNTF Mflv_1302|M.gilvum_PYR-GCK TVFSVVRNASVPYGIATADEPNISSTRWRTVIDHKSLRYFFESALSPNTF MSMEG_5454|M.smegmatis_MC2_155 SVMAIMRNVSVPFGAPYG-EFGVYNTEYRTVSDLTHKLYFFELSTSPSVI :*:: :*. ..* * . : .: .* :*:* * *:*: .*..: MMAR_2570|M.marinum_M WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKFEPAAPFHFLAPSPR MUL_3191|M.ulcerans_Agy99 WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKVEPAAPFHFLAPSPR TH_3250|M.thermoresistible__bu WVELQNLDFSEDAPVRRLSLGEGEKTIYAGDASARFEPADPFTFLSVPA- Mvan_5516|M.vanbaalenii_PYR-1 WVDLKNLDFSVDAPVRRLELGEGEKTIYAGDTSAQFQPAEPFAFLAVP-- Mflv_1302|M.gilvum_PYR-GCK WVELKNLDLSAGASALRLQLGEGEKTVYAGDASGRFEPAEPFAFLGLA-- MSMEG_5454|M.smegmatis_MC2_155 WVEFDHLELPAAGQAVAIDP---YDETLTGNVTDRFTPRE-LAF------ **::.::::. . : . *:.: :. * : *