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M. gilvum PYR-GCK Mflv_1302 (-)

annotation: choloylglycine hydrolase
coordinates: 1356407 - 1357390
length: 327

MCTRVVYLGDEDRVVTGRSMDWKVEIGTNLWALPRGVARTGQAGPDSVEWTAKYGSVVATGYDISTTDGL
NEAGLAANLLWLAESQYPANTGDRPALAISLWAQYMLDNFATVAEAVAALTATPLRVVTAEVPGQERMAT
VHLALSDATGDSAIVEYIDGEQVIHHGRQYQVMTNSPTFDKQLAITEYWKEIGGTVMLPGTNRAADRFVR
ASFYIDAVPKTDDPLLAAATVFSVVRNASVPYGIATADEPNISSTRWRTVIDHKSLRYFFESALSPNTFW
VELKNLDLSAGASALRLQLGEGEKTVYAGDASGRFEPAEPFAFLGLA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_1302--100% (327)choloylglycine hydrolase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97-----
M. tuberculosis H37Rv-----
M. leprae Br4923-----
M. abscessus ATCC 19977-----
M. marinum MMMAR_2570-3e-9149.69% (326) hydrolase/amidase
M. avium 104-----
M. smegmatis MC2 155MSMEG_5454-1e-5338.11% (328) choloylglycine hydrolase, putative
M. thermoresistible (build 8)TH_3250-1e-15980.98% (326) PUTATIVE Choloylglycine hydrolase
M. ulcerans Agy99MUL_3191-2e-9049.39% (326) hydrolase/amidase
M. vanbaalenii PYR-1Mvan_5516-1e-16082.52% (326) choloylglycine hydrolase

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_2570|M.marinum_M               ----------MCTRILYKTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR
MUL_3191|M.ulcerans_Agy99           ----------MCTRILYRTGTGTYVTGRGMDWNDLDMQTDCWVFPRGMRR
TH_3250|M.thermoresistible__bu      ----------MCTRVVYLGTSDRVITGRSMDWK-FEIATNLWALPRGINR
Mvan_5516|M.vanbaalenii_PYR-1       MSERCPTVLDVCTRVVYLGTNDRVVTGRSMDWK-VEIGTNLWVLPRGIRR
Mflv_1302|M.gilvum_PYR-GCK          ----------MCTRVVYLGDEDRVVTGRSMDWK-VEIGTNLWALPRGVAR
MSMEG_5454|M.smegmatis_MC2_155      ----------MCTRVLWNSNKLAVLSGRSMDWP-ESTEPLIVAFASGRDR
                                              :***:::       ::**.***   .  .   .:. *  *

MMAR_2570|M.marinum_M               DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL
MUL_3191|M.ulcerans_Agy99           DGGVGA-------GSITWTSKYGSVILSIYDLATSDGVNEAGMVGNLLYL
TH_3250|M.thermoresistible__bu      TGQAGP-------DSVEWTAKYGSVVATGYDICTTDGVNEAGLAVNLLWL
Mvan_5516|M.vanbaalenii_PYR-1       AGQAGP-------DSLEWTAKYGSVVATAYDICSTDGVNEAGLAANLLWL
Mflv_1302|M.gilvum_PYR-GCK          TGQAGP-------DSVEWTAKYGSVVATGYDISTTDGLNEAGLAANLLWL
MSMEG_5454|M.smegmatis_MC2_155      DGGLLAGHPVIPENPLRWTSRHASLATTVYGLGTVDGINAAGLGVHALYL
                                     *   .       ..: **:::.*:  : *.: : **:* **:  : *:*

MMAR_2570|M.marinum_M               TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVEAMSADPMTVVSAD
MUL_3191|M.ulcerans_Agy99           TESDYGDQGARSKPTISVGAWLQYLLDNFGTVAEAVQAMSADPMTVVSAD
TH_3250|M.thermoresistible__bu      AESQYPADGA-GGPAISLALWGQYVLDNFATVAEAVTALAATPLRVATAE
Mvan_5516|M.vanbaalenii_PYR-1       AESQYPADDA-GGPAVALSLWAQYVLDNFATVAEAVAALTANPLRVATAE
Mflv_1302|M.gilvum_PYR-GCK          AESQYPANTG-DRPALAISLWAQYMLDNFATVAEAVAALTATPLRVVTAE
MSMEG_5454|M.smegmatis_MC2_155      KSTDVGPRNP-DLPGLHTGLWAQYLLDQAATVEEALALMQDVQLVMVG--
                                     .::       . * :  . * **:**: .** **:  :    : :.   

MMAR_2570|M.marinum_M               AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ
MUL_3191|M.ulcerans_Agy99           AP-NGRAASVHVALSDAGGDSAIFEYLDAKLVIHHSRDHTVLTNSPVFEQ
TH_3250|M.thermoresistible__bu      VPGEQRMATLHLAMSDATGDSAVVEYIDGRQTVHHGRQYQVMTNSPTFDK
Mvan_5516|M.vanbaalenii_PYR-1       VPGQQRMATLHLAMSDASGDSAIVEYIDGRQTIHHDRSHQVMTNSPTFDK
Mflv_1302|M.gilvum_PYR-GCK          VPGQERMATVHLALSDATGDSAIVEYIDGEQVIHHGRQYQVMTNSPTFDK
MSMEG_5454|M.smegmatis_MC2_155      --ARGREATLHLAIEDATGDSAILELEAGKLAVHHGRQFTLMTNDPTYDE
                                       . * *::*:*:.** ****:.*   .. .:**.*.. ::**.*.:::

MMAR_2570|M.marinum_M               QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA
MUL_3191|M.ulcerans_Agy99           QLAINTYWDLIGGH--NMLPGTITSADRFVRASYALKASPQFSDRRQAVA
TH_3250|M.thermoresistible__bu      QLAITEYWEQIGGT--VMLPGTNRAADRFVRASFYINAVPKSDDPQLSVA
Mvan_5516|M.vanbaalenii_PYR-1       QLAITEYWEEIGGT--VMLPGTNRAADRFVRAAFYINAVPKCDDPVLAVA
Mflv_1302|M.gilvum_PYR-GCK          QLAITEYWKEIGGT--VMLPGTNRAADRFVRASFYIDAVPKTDDPLLAAA
MSMEG_5454|M.smegmatis_MC2_155      QLALLAKQDFSHPTRELPLPGNVNPVDRFQRAAYYSALLPEPTGIRQGVA
                                    ***:    .         ***.  ..*** **::     *:  .   ..*

MMAR_2570|M.marinum_M               AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI
MUL_3191|M.ulcerans_Agy99           AVFSQMRSIGVPLGMSDPDKPNIASTLWRSVVDHDARRYYFDSVINPSVI
TH_3250|M.thermoresistible__bu      AVMSVMRNVSTPYGIATSDEPNISSTRWRTVVDHKAQRYFFESALSPNTF
Mvan_5516|M.vanbaalenii_PYR-1       AVFSVVRNVSTPYGIATSDEPNISSTRWRTVVDHKSLRYFFESALSPNTF
Mflv_1302|M.gilvum_PYR-GCK          TVFSVVRNASVPYGIATADEPNISSTRWRTVIDHKSLRYFFESALSPNTF
MSMEG_5454|M.smegmatis_MC2_155      SVMAIMRNVSVPFGAPYG-EFGVYNTEYRTVSDLTHKLYFFELSTSPSVI
                                    :*:: :*. ..* * .   : .: .* :*:* *     *:*:   .*..:

MMAR_2570|M.marinum_M               WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKFEPAAPFHFLAPSPR
MUL_3191|M.ulcerans_Agy99           WVDLDKVDLTPAAQPMKLTVGVPDD--QGGDVSQKVEPAAPFHFLAPSPR
TH_3250|M.thermoresistible__bu      WVELQNLDFSEDAPVRRLSLGEGEKTIYAGDASARFEPADPFTFLSVPA-
Mvan_5516|M.vanbaalenii_PYR-1       WVDLKNLDFSVDAPVRRLELGEGEKTIYAGDTSAQFQPAEPFAFLAVP--
Mflv_1302|M.gilvum_PYR-GCK          WVELKNLDLSAGASALRLQLGEGEKTVYAGDASGRFEPAEPFAFLGLA--
MSMEG_5454|M.smegmatis_MC2_155      WVEFDHLELPAAGQAVAIDP---YDETLTGNVTDRFTPRE-LAF------
                                    **::.::::.  .    :      .    *:.: :. *   : *