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MAAVAVGTPSTRYRPNSMHVLVIAVVGLALVGGILRGFVAGTPGVATAATVFCGIFVQALPFLALGVVIS GAVAALVTPDRLARWLPKRPSAAILAAGVGGFALPGCECGSVPIARRLFGESTVGAAALTFMLAAPAINP AVLVATAVAFPGEPGMVVARCAASLITALIMGGLWARFGLPRWITRRVPHEHSTGGSRWTAFSEAARHDF LQASSFLVVGAAAAAALHVLVPAWMFEHLAGQLLLGIAVMALLAVVLALCSEADAFVAASLSMLPLLPRL VFLVVGPAVDIKLFAMQVGMFGRAFAIRFAPVTFVVATATATIVGLLVLGNR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5330 | - | - | 100% (332) | permease |
| M. vanbaalenii PYR-1 | Mvan_5316 | - | 3e-07 | 24.62% (199) | permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3940 | - | 4e-05 | 25.49% (204) | transmembrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv3910 | - | 4e-05 | 25.49% (204) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2861 | - | 1e-129 | 68.20% (327) | hypothetical protein MAB_2861 |
| M. marinum M | - | - | - | - | - |
| M. avium 104 | MAV_4878 | - | 1e-121 | 67.60% (321) | permease |
| M. smegmatis MC2 155 | MSMEG_6060 | - | 1e-140 | 73.62% (345) | permease |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------MAAVAVGTPSTRYRPNSMHVLVIA
MSMEG_6060|M.smegmatis_MC2_155 -----------------------------MAMNLAVARWRPNSMQVLVFG
MAB_2861|M.abscessus_ATCC_1997 -----------------------------MTVAASEDRRWFGSTEILVVA
MAV_4878|M.avium_104 -----------------------------MATLKAVRGWRIGSMEVLVGI
Mb3940|M.bovis_AF2122/97 MRPSPGEVPTASQRQPELSDAALVSHSWAMAFATLISRITGFARIVLLAA
Rv3910|M.tuberculosis_H37Rv MRPSPGEVPTASQRQPELSDAALVSHSWAMAFATLISRITGFARIVLLAA
:: : :*:
Mvan_5330|M.vanbaalenii_PYR-1 VVGLALVG-----GILRGFVAGTPGVATAATVFCGIFVQALPFLALG-VV
MSMEG_6060|M.smegmatis_MC2_155 IVGLALAG-----TTLRAFVADTPDVATAATVFCGVFVQALPFLALG-VV
MAB_2861|M.abscessus_ATCC_1997 LIAMALAA-----GWLRGIVDANEKLATAGTVFCGVFVQAVPFLALG-VI
MAV_4878|M.avium_104 LLACALAA-----TTLRTVVGNSAALSTVGTVFCGVFVQAIPFLVLG-VV
Mb3940|M.bovis_AF2122/97 ILGAALASSFSVANQLPNLVAALVLEATFTAIFVPVLARAEQDDPDGGAA
Rv3910|M.tuberculosis_H37Rv ILGAALASSFSVANQLPNLVAALVLEATFTAIFVPVLARAEQDDPDGGAA
::. **.. * .* :* ::* ::.:* * .
Mvan_5330|M.vanbaalenii_PYR-1 ISGAVAALVTPDRLARWLPKRPSAAILAAGVGGFALPGCECGSVPIARRL
MSMEG_6060|M.smegmatis_MC2_155 ISGLIAVVVTPDRLARWLPRRTSAAIVVAGVGGAALPGCECGSVPVARRL
MAB_2861|M.abscessus_ATCC_1997 VSGLVATFVTPERLARWLPNRSVAAVAVAGIGGAALPGCECGSVPVARRL
MAV_4878|M.avium_104 VSGLIAVFVSPERLARWLPRRPATAVLAAGAGGMALPGCECGSVPLARRL
Mb3940|M.bovis_AF2122/97 FVRRLVTLATTLLLGATTLSVLAAPLLVRLMLGTNPQVNEPLTTAFAYLL
Rv3910|M.tuberculosis_H37Rv FVRRLVTLATTLLLGATTLSVLAAPLLVRLMLGTNPQVNEPLTTAFAYLL
. :....:. *. :.: . * * :...* *
Mvan_5330|M.vanbaalenii_PYR-1 FGEST----------------VGAAALTFMLAAPAINPAV-------LVA
MSMEG_6060|M.smegmatis_MC2_155 FGDGAGAGTDKGTDKGTGKGHVGAAALTFMLAAPAINPVV-------LVA
MAB_2861|M.abscessus_ATCC_1997 YGPG----------------SVGAAALTFMLSAPAINPVV-------LVA
MAV_4878|M.avium_104 FGEGG---------------ATGAAALTFMLAAPAINPVV-------LAS
Mb3940|M.bovis_AF2122/97 LPQVLVYG--------LSSVFMAILNTRNVFGPPAWAPVVNNVVAIATLA
Rv3910|M.tuberculosis_H37Rv LPQVLVYG--------LSSVFMAILNTRNVFGPPAWAPVVNNVVAIATLA
. ::..** *.* :
Mvan_5330|M.vanbaalenii_PYR-1 TAVAFPGEPGMVVARCAASLITALIMGGLWARFGLPRWITRRVPHEHSTG
MSMEG_6060|M.smegmatis_MC2_155 TAVAFPEHPQMVAARCAASLLTAIIMGAAWARFGNPAWITHRLARPDHSA
MAB_2861|M.abscessus_ATCC_1997 TAVAFPGQPRMVLARVVASLLTAMVMGMVWSRWGRDSWVTRRLPHAHAGS
MAV_4878|M.avium_104 TAVAFPGLPGMVFARLGASLLTAVVMGWVWSRWGRPEWITRALPASRAPA
Mb3940|M.bovis_AF2122/97 VYLAVPGELSVDPVRMGNAKLLVLGIGTTAGVFAQTAVLLVAIRREHISL
Rv3910|M.tuberculosis_H37Rv VYLAVPGELSVDPVRMGNAKLLVLGIGTTAGVFAQTAVLLVAIRREHISL
. :*.* : .* : : .: :* . :. : :
Mvan_5330|M.vanbaalenii_PYR-1 G---------SRWTAFSEAARHDFLQASSFLVVG-AAAAAALHVLVPAWM
MSMEG_6060|M.smegmatis_MC2_155 G---------SRWAAFTEAARHDFLSACSYLVVG-AAAAAALHVLVPPWV
MAB_2861|M.abscessus_ATCC_1997 S---------SRWATFAEAARHDFLQAASYLAIG-AVAAAALHVLVPTWV
MAV_4878|M.avium_104 E---------SRLEVFTEAARHDFLQAASYLVLG-AAAAALLHVAVPPWV
Mb3940|M.bovis_AF2122/97 RPLWGIDQRLKRFGAMAAAMVLYVLISQLGLVVGNRIASTAAASGPAIYN
Rv3910|M.tuberculosis_H37Rv RPLWGIDQRLKRFGAMAAAMVLYVLISQLGLVVGNRIASTAAASGPAIYN
.* .:: * .* : *.:* *:: . :
Mvan_5330|M.vanbaalenii_PYR-1 FEHLAGQLLLGIAVMALLAVVLALCS-----------EADAFVAASLSML
MSMEG_6060|M.smegmatis_MC2_155 YEHVAGQIALGVITMAVLAVVLALCS-----------EADAFVAASLTML
MAB_2861|M.abscessus_ATCC_1997 FEHLAGNLVVGVVTMALLAVVLALCS-----------EADAFVAASITMM
MAV_4878|M.avium_104 FTHLAGDLALGVALMAALAVVLALCS-----------EADAFVAASLTMV
Mb3940|M.bovis_AF2122/97 YTWLVLMLPFGMIGVTVLTVVMPRLSRNAAADDTPAVLADLSLATRLTMI
Rv3910|M.tuberculosis_H37Rv YTWLVLMLPFGMIGVTVLTVVMPRLSRNAAADDTPAVLADLSLATRLTMI
: :. : .*: :: *:**:. * ** :*: ::*:
Mvan_5330|M.vanbaalenii_PYR-1 PLLPRLVFLVVG-PAVDIKLFAMQ------VGMFGRAFAIR---------
MSMEG_6060|M.smegmatis_MC2_155 PLLPRLVFLVVG-PAVDIKLFAMQ------AGMFGRAFAIR---------
MAB_2861|M.abscessus_ATCC_1997 PLIPRLVFLVVG-PAVDVKLIAMQ------SGMFGRAFAAR---------
MAV_4878|M.avium_104 PLLPRLVFLVVG-PAVDVKLFAMQ------AGMFGRAFAAR---------
Mb3940|M.bovis_AF2122/97 TLIPTVAFMTVGGPAIGSALFAYGNFGDVDAGYLGAAIALSAFTLIPYAL
Rv3910|M.tuberculosis_H37Rv TLIPTVAFMTVGGPAIGSALFAYGNFGDVDAGYLGAAIALSAFTLIPYAL
.*:* :.*:.** **:. *:* * :* *:*
Mvan_5330|M.vanbaalenii_PYR-1 --------------FAPVTFVVAT--------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------FAPATFAVAT--------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------FAPLTFVVAT--------------------------
MAV_4878|M.avium_104 --------------FAPCTLLVAT--------------------------
Mb3940|M.bovis_AF2122/97 VLLQLRVFYAREQPWTPITIIVVITGVKILGSLLAPHITGDPQLVAAYLG
Rv3910|M.tuberculosis_H37Rv VLLQLRVFYAREQPWTPITIIVVITGVKILGSLLAPHITGDPQLVAAYLG
::* *: *.
Mvan_5330|M.vanbaalenii_PYR-1 -------ATATIVGLLVLGNR-----------------------------
MSMEG_6060|M.smegmatis_MC2_155 -------LVATVVGLLILGPR-----------------------------
MAB_2861|M.abscessus_ATCC_1997 -------LVATGIGLAVLGAS-----------------------------
MAV_4878|M.avium_104 -------VSACGIGFFVLGAR-----------------------------
Mb3940|M.bovis_AF2122/97 LANGLGFLAGTIVGYYILRRALRPDGGQLIGVGEARTALVTVAASLLAGL
Rv3910|M.tuberculosis_H37Rv LANGLGFLAGTIVGYYILRRALRPDGGQLIGVGEARTVLVTVAASLLAGL
. :* :*
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 LAHVADRLLGLSELTAHAGSVGSLLRLSVLALIMLPILAAVTLCARVPEA
Rv3910|M.tuberculosis_H37Rv LAHVADRLLGLSELTAHAGSVGSLLRLSVLALIMLPILAAVTLCARVPEA
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 RAALDAVRARIRSRRLKTGPQTQNVLDQSSRPGPVTYPERRRLAPPRGKS
Rv3910|M.tuberculosis_H37Rv RAALDAVRARIRSRRLKTGPQTQNVLDQSSRPGPVTYPERRRLAPPRGKS
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 VVHEPIRRRPPEQVARAGRAKGPEVIDRPSENASFGAASGAELPRPVADE
Rv3910|M.tuberculosis_H37Rv VVHEPIRRRPPEQVARAGRAKGPEVIDRPSENASFGAASGAELPRPVADE
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 LQLDAPAGRDPGPVSRPHPSDLQNGDLPADAARGPIAFDALREPDRESSA
Rv3910|M.tuberculosis_H37Rv LQLDAPAGRDPGPVSRPHPSDLQNGDLPADAARGPIAFDALREPDRESSA
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 PPDDVQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVD
Rv3910|M.tuberculosis_H37Rv PPDDVQLVPGARIANGRYRLLIFHGGVPPLQFWQALDTALDRQVALTFVD
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 PQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRG
Rv3910|M.tuberculosis_H37Rv PQGVLPDDVLQETLSRTLRLSRIDKPGVARVLDVVHTRAGGLVVAEWIRG
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 GSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSID
Rv3910|M.tuberculosis_H37Rv GSLQEVADTSPSPVGAIRAMQSLAAAADAAHRAGVALSIDHPSRVRVSID
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 GDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAE
Rv3910|M.tuberculosis_H37Rv GDVVLAYPATMPDANPQDDIRGIGASLYALLVNRWPLPEAGVRSGLAPAE
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 RDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATA
Rv3910|M.tuberculosis_H37Rv RDTAGQPIEPADIDRDIPFQISAVAARSVQGDGGIRSASTLLNLMQQATA
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 VADRTEVLGPIDEAPVSAAPRTSAPNSETYTRRRRNLLIGIGAGAAVLMV
Rv3910|M.tuberculosis_H37Rv VADRTEVLGPIDEAPVSAAPRTSAPNSETYTRRRRNLLIGIGAGAAVLMV
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 ALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASSAPPGSVVKPTK
Rv3910|M.tuberculosis_H37Rv ALLVLASVLSRIFGDVSGGLNKDELGLNAPTASTSAASSAPPGSVVKPTK
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 VTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPSFKNGVGLML
Rv3910|M.tuberculosis_H37Rv VTVFSPDGGADNPGEADLAIDGNPATSWKTDIYTDPVPFPSFKNGVGLML
Mvan_5330|M.vanbaalenii_PYR-1 --------------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 --------------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_4878|M.avium_104 --------------------------------------------------
Mb3940|M.bovis_AF2122/97 QLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPG
Rv3910|M.tuberculosis_H37Rv QLPQATVVGTVAIDVASTGTKVEIRSASTPTPATLEDTAVLTSATALRPG
Mvan_5330|M.vanbaalenii_PYR-1 ------------------------------------------
MSMEG_6060|M.smegmatis_MC2_155 ------------------------------------------
MAB_2861|M.abscessus_ATCC_1997 ------------------------------------------
MAV_4878|M.avium_104 ------------------------------------------
Mb3940|M.bovis_AF2122/97 HNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS
Rv3910|M.tuberculosis_H37Rv HNTISVEAAAPTSNLLVWISTLGTTDGKSQADISEITIYAAS