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STASRDAPAAGPGGPSERTRTLGILLLAAFGWVGAYVLNEHLWDAAVGWLGLDLHTRAVGAVHFFLYDTV KIFLLLTGLMFVVGMLRASLDLDRARDYLRGRGLFVGLVLAVFLGVVTPFCSCSSIPLFIGFVAAGIPLS ITLTFLIASPLVSEIAAIMIGDQFGWHIAAVYVVAGSVLSLVIGWIFSRFDLSRWVEPMVFTTKVAALRA DGRVPSLAERVDAAVDETKDIFRSVWLWVLLGVGIGAVIHGWVPADFFVRFAGPGNPFAVVVATLAGVPL YVNGAGVVPIAEALWAKGMSLGTVMAFTMSTIALSVPQAVMLRRVMKPPLLALFFGTVAFGIMIIGFLFN LVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5316 | - | - | 100% (354) | permease |
| M. vanbaalenii PYR-1 | Mvan_5330 | - | 3e-07 | 24.62% (199) | permease |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2987 | - | 4e-13 | 23.68% (266) | integral membrane protein |
| M. gilvum PYR-GCK | - | - | - | - | - |
| M. tuberculosis H37Rv | Rv2963 | - | 4e-13 | 23.68% (266) | integral membrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2861 | - | 4e-07 | 22.36% (237) | hypothetical protein MAB_2861 |
| M. marinum M | MMAR_1754 | - | 9e-13 | 22.93% (266) | hypothetical protein MMAR_1754 |
| M. avium 104 | MAV_3787 | - | 1e-11 | 22.56% (266) | hypothetical protein MAV_3787 |
| M. smegmatis MC2 155 | MSMEG_6060 | - | 3e-05 | 23.26% (215) | permease |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_1997 | - | 1e-12 | 23.31% (266) | hypothetical protein MUL_1997 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2987|M.bovis_AF2122/97 MTSTKVEDRVTAAVLGAIGHALALTASMTWEILWALILGFALSAVVQAVV
Rv2963|M.tuberculosis_H37Rv MTSTKVEDRVTAAVLGAIGHALALTASMTWEILWALILGFALSAVVQAVV
MMAR_1754|M.marinum_M ---------MAGTVWGAVGHALALTGSMTWEILWALILGFTLSAMVQAVV
MUL_1997|M.ulcerans_Agy99 ---------MAGTVLGAVGHALALTGSMTWEILWALILGFTLSAMVQAVV
MAV_3787|M.avium_104 ----------MTTVLSAVGHALAVAGSMTWEILWALILGFALSAVVQAVV
MAB_2861|M.abscessus_ATCC_1997 ----------MTVAASEDRRWFGSTEILVVALIAMALAAGWLRGIVDANE
MSMEG_6060|M.smegmatis_MC2_155 ----------MAMNLAVARWRPNSMQVLVFGIVGLALAGTTLRAFVADTP
Mvan_5316|M.vanbaalenii_PYR-1 -------MSTASRDAPAAGPGGPSERTRTLGILLLAAFGWVGAYVLNEHL
. :: . .:
Mb2987|M.bovis_AF2122/97 RRSTIVTLLGDDRPRTLVIATGLGAASSSCSYAAVALARSLFRKGANFTA
Rv2963|M.tuberculosis_H37Rv RRSTIVTLLGDDRPRTLVIATGLGAASSSCSYAAVALARSLFRKGANFTA
MMAR_1754|M.marinum_M RRSTIVALMGNDKPRTLAVAAGLGAASSSCSYAAVALARSLFRKGANFTA
MUL_1997|M.ulcerans_Agy99 RRSTIVALMGNDKPRTLAVAAGLGAASSSCSYAAVALARSLFRKGANFTA
MAV_3787|M.avium_104 RRTTIVALMGDARPRTLAVSAGLGAASSSCSYAAVALARALFRKGADFTA
MAB_2861|M.abscessus_ATCC_1997 KLATAGTVFCGVFVQAVPFLA-LGVIVSGLVATFVTPER----------L
MSMEG_6060|M.smegmatis_MC2_155 DVATAATVFCGVFVQALPFLA-LGVVISGLIAVVVTPDR----------L
Mvan_5316|M.vanbaalenii_PYR-1 WDAAVGWLGLDLHTRAVGAVHFFLYDTVKIFLLLTGLMFVVGMLRASLDL
:: : . ::: : .
Mb2987|M.bovis_AF2122/97 AMAFEIGSTNLVVELGIILALLMGWQFTAAEFVGGPIMILVLAVLFRLFV
Rv2963|M.tuberculosis_H37Rv AMAFEIGSTNLVVELGIILALLMGWQFTAAEFVGGPIMILVLAVLFRLFV
MMAR_1754|M.marinum_M AMAFEIGSTNLVVELGIILALLMGWQFTAAEFVGGPLMIIVLAVLFRLFV
MUL_1997|M.ulcerans_Agy99 AMAFEIGSTNLVVELGIILALLMGWQFTAAESVGGPLMIIVLAVLFRLFV
MAV_3787|M.avium_104 AMAFEIGSTNLVVELGIILALLMGWQFTAAEFVGGPLMIVVLALLFRLFV
MAB_2861|M.abscessus_ATCC_1997 ARWLPNRSVAAVAVAGIGGAALPGCECGSVPVA-------------RRLY
MSMEG_6060|M.smegmatis_MC2_155 ARWLPRRTSAAIVVAGVGGAALPGCECGSVPVA-------------RRLF
Mvan_5316|M.vanbaalenii_PYR-1 DRARDY-LRGRGLFVGLVLAVFLGVVTPFCSCSS-----------IPLFI
*: * : * :
Mb2987|M.bovis_AF2122/97 GARLIDAAREQAERGLAGSMEGHAAMDMSIKREGSFWRRLLSPPGFTSIA
Rv2963|M.tuberculosis_H37Rv GARLIDAAREQAERGLAGSMEGHAAMDMSIKREGSFWRRLLSPPGFTSIA
MMAR_1754|M.marinum_M RTRLIDAAREQAERGIAGSMEGHAAMDMSVGGEDSFLRRLFSRRAFTSVS
MUL_1997|M.ulcerans_Agy99 RTRLIDAAREQAERGITGSMEGHAAMDMSVGGEDSFLRRLFSRRAFTSVS
MAV_3787|M.avium_104 RPRLVDAARAQAQRGIAGSMEGHAAMDMSVAGDGPFWRRLLSPAGFTAVS
MAB_2861|M.abscessus_ATCC_1997 GPGS----------------VGAAALTFMLS--APAINPVVLVATAVAFP
MSMEG_6060|M.smegmatis_MC2_155 GDGAGAGTDKGTDKGTGKGHVGAAALTFMLA--APAINPVVLVATAVAFP
Mvan_5316|M.vanbaalenii_PYR-1 GFVAAG-------------IPLSITLTFLIASPLVSEIAAIMIGDQFGWH
:: : : . .
Mb2987|M.bovis_AF2122/97 HVFVMEWLAILRDLILGLLIA-GAIAAWVPESFWQSFFLANHPAWSA-VW
Rv2963|M.tuberculosis_H37Rv HVFVMEWLAILRDLILGLLIA-GAIAAWVPESFWQSFFLANHPAWSA-VW
MMAR_1754|M.marinum_M HVFVMEWAAILRDLVLGLVIA-GAIAAWVPETFWQNFFLANHPNLSV-VW
MUL_1997|M.ulcerans_Agy99 HVFVMEWAAILRYLVLGLVIA-GAIAAWVPETFWQNFFLANHPNLSV-VW
MAV_3787|M.avium_104 HVFVMEWLAILRDLVLGLLIA-GAVAAWVPEKFWQSFFLVDHPGWSV-LW
MAB_2861|M.abscessus_ATCC_1997 GQPRMVLARVVASLLTAMVMG-MVWSRWGRDSWVTRRLPHAHAGSSS-RW
MSMEG_6060|M.smegmatis_MC2_155 EHPQMVAARCAASLLTAIIMG-AAWARFGNPAWITHRLARPDHSAGS-RW
Mvan_5316|M.vanbaalenii_PYR-1 IAAVYVVAGSVLSLVIGWIFSRFDLSRWVEPMVFTTKVAALRADGRVPSL
*: . ::. : : .
Mb2987|M.bovis_AF2122/97 GPIIGPIVAIVSFVCSIGNVPLAAVLWNGGISFGGVIAFIFADLLILPIL
Rv2963|M.tuberculosis_H37Rv GPIIGPIVAIVSFVCSIGNVPLAAVLWNGGISFGGVIAFIFADLLILPIL
MMAR_1754|M.marinum_M GPLVGPVVAIVSFVCSIGNVPLAAVLWNGGISFGGVIAFIFADLLILPIL
MUL_1997|M.ulcerans_Agy99 GPPVGPVVAIVSFVCSIGNVPLAAVLWNGGISFGGVIAFIFADLLILPIL
MAV_3787|M.avium_104 GPIVGPLVAIVSFVCSIGNVPLAAVLWNGGISFGGVIAFIYADLLILPIL
MAB_2861|M.abscessus_ATCC_1997 ATFAEAARHDFLQAASYLAIGAVAAAALHVLVPTWVFEHLAGNLVVGVVT
MSMEG_6060|M.smegmatis_MC2_155 AAFTEAARHDFLSACSYLVVGAAAAAALHVLVPPWVYEHVAGQIALGVIT
Mvan_5316|M.vanbaalenii_PYR-1 AERVDAAVDETKDIFRSVWLWVLLGVGIGAVIHGWVPADFFVRFAGPGNP
. . : : * . :
Mb2987|M.bovis_AF2122/97 NIYRKYYGARMMLVLLGTFYASMVVAGYLIELLFGTTNLIPSQRSATVMT
Rv2963|M.tuberculosis_H37Rv NIYRKYYGARMMLVLLGTFYASMVVAGYLIELLFGTTNLIPSQRSATVMT
MMAR_1754|M.marinum_M NIYRKYYGTKMMLTLLGTFYVSMVVAGYLIELIFGAANLIPRQRSATVLH
MUL_1997|M.ulcerans_Agy99 NIYRKYYGTKMMLTLLGTFYVSMVVAGYLIELIFGAANLIPRQRSATVLH
MAV_3787|M.avium_104 NIYRKYYGTRMMLTLLGTFYAAMVAAGYLVELIFGTSGLIPAERAATVAE
MAB_2861|M.abscessus_ATCC_1997 -----MALLAVVLALCSEADAFVAASITMMPLIPRLVFLVVGPAVDVKLI
MSMEG_6060|M.smegmatis_MC2_155 -----MAVLAVVLALCSEADAFVAASLTMLPLLPRLVFLVVGPAVDIKLF
Mvan_5316|M.vanbaalenii_PYR-1 FAVVVATLAGVPLYVNGAGVVPIAEALWAKGMSLGTVMAFT--MSTIALS
: * : . . :. : : .
Mb2987|M.bovis_AF2122/97 AEISWNYTTWLNVIFLVIAAALVVRFITSGGLPMLRMMGGSPDAPHDHHD
Rv2963|M.tuberculosis_H37Rv AEISWNYTTWLNVIFLVIAAALVVRFITSGGLPMLRMMGGSPDAPHDHHD
MMAR_1754|M.marinum_M AGISWNYTTWLNIIFLGIAAVLVTRFITSGGMPMLRMMGGSPEAEGHQHG
MUL_1997|M.ulcerans_Agy99 AGISWNYTTWLNIIFLGIAAVLVTRFITSGGMPMLRMMGGSPEAEGHQHG
MAV_3787|M.avium_104 ASVSWNYTTWLNVAFLVLALVLIVRFVRTNGLAMVRMMGGSPDPAEHRH-
MAB_2861|M.abscessus_ATCC_1997 AMQSGMFGRAFAARFAPLTFVVATLVATGIGLAVLGAS------------
MSMEG_6060|M.smegmatis_MC2_155 AMQAGMFGRAFAIRFAPATFAVATLVATVVGLLILGPR------------
Mvan_5316|M.vanbaalenii_PYR-1 VPQAVMLRRVMKPPLLALFFGTVAFGIMIIGFLFNLVG------------
. : : : . *: .
Mb2987|M.bovis_AF2122/97 RHDDHLGH
Rv2963|M.tuberculosis_H37Rv RHDDHLGH
MMAR_1754|M.marinum_M -HQCH---
MUL_1997|M.ulcerans_Agy99 -HQCH---
MAV_3787|M.avium_104 --------
MAB_2861|M.abscessus_ATCC_1997 --------
MSMEG_6060|M.smegmatis_MC2_155 --------
Mvan_5316|M.vanbaalenii_PYR-1 --------