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M. vanbaalenii PYR-1 Mvan_5109 (-)

annotation: glycine cleavage T protein (aminomethyl transferase)
coordinates: 5472107 - 5473192
length: 361

MSAVPAPDIGPDAGAVWHYGDPLGEQRAAAQGAVVVDRSHRAVLSLTGAERNSWLHTISSQHVSDLADGT
VTENLSLDGQGRVEDHWVQTQLDGRTVLDTEPWRGEPLLSFLRKMVFWADVVVEPADLGVLSLLGPGLTD
PAVLDAVGLPALPAPNSAVELPGGGFIRRLPGPAVEVDVVVPRDELAAWRDRLVAAGVRPAGVWAYEAHR
VAARRPRLGVDTDERTIPHEVGWIGGPGVGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGASDRP
STGDPLLAGGRTVGRLGTVVDHVDEGVIALALLKRGLPADTALTTGGEVHAAATIDPDSMPPADGVGAGR
LAVDRLRGGTA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. vanbaalenii PYR-1Mvan_5109--100% (361)glycine cleavage T protein (aminomethyl transferase)

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0834c-1e-15472.40% (366) hypothetical protein Mb0834c
M. gilvum PYR-GCKMflv_1638-1e-17382.30% (356) glycine cleavage T protein (aminomethyl transferase)
M. tuberculosis H37RvRv0811c-1e-15472.40% (366) hypothetical protein Rv0811c
M. leprae Br4923MLBr_02203-1e-14368.49% (365) hypothetical protein MLBr_02203
M. abscessus ATCC 19977MAB_0730c-1e-11661.46% (371) hypothetical protein MAB_0730c
M. marinum MMMAR_4878-1e-16376.11% (360) hypothetical protein MMAR_4878
M. avium 104MAV_0750-1e-15876.04% (359) glycine cleavage T-protein (aminomethyl transferase)
M. smegmatis MC2 155MSMEG_5796-1e-16677.72% (359) glycine cleavage T-protein (aminomethyl transferase)
M. thermoresistible (build 8)TH_0071-1e-15373.82% (359) CONSERVED HYPOTHETICAL PROTEIN
M. ulcerans Agy99MUL_0420-1e-16275.83% (360) hypothetical protein MUL_0420

CLUSTAL 2.0.9 multiple sequence alignment


Mb0834c|M.bovis_AF2122/97           ----MAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTL
Rv0811c|M.tuberculosis_H37Rv        ----MAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTL
MLBr_02203|M.leprae_Br4923          ----MNAVLAPDPGPDAGAIWHFGDPLGEQRSAETDAVLVDRSHRATLTL
MMAR_4878|M.marinum_M               ----MSAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTL
MUL_0420|M.ulcerans_Agy99           ----MSAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTL
MAV_0750|M.avium_104                ---MTHPVPAPDTGPDAGAVWHYGDPLGEQRAAETEALVIDRSHRGVLTL
TH_0071|M.thermoresistible__bu      ----MSAVPSPESGPDAGTVWHHGDPFGEQRAATTEVVVVDRSHRAALTL
Mvan_5109|M.vanbaalenii_PYR-1       ----MSAVPAPDIGPDAGAVWHYGDPLGEQRAAAQGAVVVDRSHRAVLSL
Mflv_1638|M.gilvum_PYR-GCK          MALETAKVPVPD-GPDAGAAWHYGDPLGEQRAAADGAVIVDRSHRAVLTL
MSMEG_5796|M.smegmatis_MC2_155      ----MSAVPTPEGSPDAGAVWHYGDPLGEQRSAATDAVVIDRSHRAVLAL
MAB_0730c|M.abscessus_ATCC_199      ----MTAVYVPEGNPDAGAVWHYGDPLGEQRAALTHAVLIDRSTRAVLAL
                                           *  *: .****: **.***:****:.   .:::*** *..*:*

Mb0834c|M.bovis_AF2122/97           DGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTT
Rv0811c|M.tuberculosis_H37Rv        DGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTT
MLBr_02203|M.leprae_Br4923          IGSDRQTWLHSISTQHVSALPDGASTQNLSLDSQGRVEDHWIQTELGGTT
MMAR_4878|M.marinum_M               TGKDRQSWLHNISTQHVSELPEGASTQNLSLDGQGRVEDHWIQTELGATT
MUL_0420|M.ulcerans_Agy99           TGKDRQSWLHNISTQHVSELPEGASTQNLSLDGQGRVEDHWIQTELGATT
MAV_0750|M.avium_104                TGADRQTWLHSISTQYVSDLPEGASTQNLSLDGQGRVEDHWIQTELAGTT
TH_0071|M.thermoresistible__bu      TGGDRKSWLHSLSTQHVSELPDGAVTENLSLDAQGRVEDHWIQTELPGVT
Mvan_5109|M.vanbaalenii_PYR-1       TGAERNSWLHTISSQHVSDLADGTVTENLSLDGQGRVEDHWVQTQLDGRT
Mflv_1638|M.gilvum_PYR-GCK          TGGERKSWLHTISSQHVSELPDGAVTENLSLDGQGRIEDHWVQTELNGRT
MSMEG_5796|M.smegmatis_MC2_155      TGKDRQGWLHNISSQHVSAQPDGTVTENLSLDMQGRVEDHWVQTELDGTT
MAB_0730c|M.abscessus_ATCC_199      SGPERLSWLHTVSSQHVADLRHGQTRENLSLDGQGRVEDHWVQTDLDGIT
                                     * :*  ***.:*:*:*:   .*   :***** ***:****:**:* . *

Mb0834c|M.bovis_AF2122/97           YLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDA
Rv0811c|M.tuberculosis_H37Rv        YLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDA
MLBr_02203|M.leprae_Br4923          YLDTEPWRGEPLLEYLRKMVFWSEVTPGSADMAMLSLLGPRLTEQAVHNA
MMAR_4878|M.marinum_M               YLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQAVLDA
MUL_0420|M.ulcerans_Agy99           YLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQAVLDA
MAV_0750|M.avium_104                YLDTEPWRAGPLLDYLRKMVFWSDVTPAAADLAVLSLLGPKLAERAVLDA
TH_0071|M.thermoresistible__bu      HLDTEPWRGEPLLTYLRKMVFWSEVTVEPADLGVLSLLGPRAVDPALLET
Mvan_5109|M.vanbaalenii_PYR-1       VLDTEPWRGEPLLSFLRKMVFWADVVVEPADLGVLSLLGPGLTDPAVLDA
Mflv_1638|M.gilvum_PYR-GCK          VIDTEPARGEALESFLRKMVFWSDVAIESSDLAVLSLLGPGVADPAVLTA
MSMEG_5796|M.smegmatis_MC2_155      YLDTESWRGEPLAAYLRKMVFWSDVQIEPADLGVLSLLGPALAGDAVLSA
MAB_0730c|M.abscessus_ATCC_199      YLDTESWRGQPLKDFLTKMVFWSKVEVAAADLKVFTLLGPDTAG--LAEK
                                     :***. *. .*  :* *****: *   .:*: :::*:**      :   

Mb0834c|M.bovis_AF2122/97           LGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRL
Rv0811c|M.tuberculosis_H37Rv        LGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRL
MLBr_02203|M.leprae_Br4923          LYLDALPDESTAVPLTAGSFVRRIPGAPAGQIELDLLVPRRESADWQSRL
MMAR_4878|M.marinum_M               LGLDALPADLMAVPLPGGGFARRMP-SSAGQIELDLLVPRGDTADWKHRL
MUL_0420|M.ulcerans_Agy99           LGLDALPADLMAVPLPGGGFARRMP-SSAGQIELDLLVPRDGTADWKHRL
MAV_0750|M.avium_104                LGVDALPAEAAAVPTRGG-FLRRMPAGPAGRLELDLVVPRAEAADWRNRL
TH_0071|M.thermoresistible__bu      VGAPPPPDGADAAPLPDGGFVRRLP---GRDTELDLVVPRAQVADWLDRL
Mvan_5109|M.vanbaalenii_PYR-1       VGLPALPAPNSAVELPGGGFIRRLP---GPAVEVDVVVPRDELAAWRDRL
Mflv_1638|M.gilvum_PYR-GCK          LGLDALPPEGTAVELADGGYVRRLP---GSEVEVDLVVPRPEVTRWFDAL
MSMEG_5796|M.smegmatis_MC2_155      LGLSALPEEATAQPLPGGGFVRRVP---SEGLELDVLVARETLDDWKQRL
MAB_0730c|M.abscessus_ATCC_199      LGIAALPELDNAVALPDGGLIRRVP-WPLAEATYDLLVPSG-----KGLA
                                    :     *    *     *   **:*         *::*            

Mb0834c|M.bovis_AF2122/97           TQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGG-PG
Rv0811c|M.tuberculosis_H37Rv        TQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGG-PG
MLBr_02203|M.leprae_Br4923          AGVGVRSAGMWAYEAHRVA----ALRPRLGVDTDQRTIPHEVGWIGG-PG
MMAR_4878|M.marinum_M               TQAGVRPAGIWTYEAHRVA----AKRPRLGVDTDERTIPHEVGWIGG-PG
MUL_0420|M.ulcerans_Agy99           TQAGVRPAGIWTYEAHRVA----AKRPRLGVDTDERTIPHEVGWIGG-PG
MAV_0750|M.avium_104                AQAGVRPGGVWAYEAHRVA----ARRPRLGVDTDERTIPHEVGWIGG-PG
TH_0071|M.thermoresistible__bu      TGAGVRRAGVWAYEALRVA----AVRPRLGVDTDERTIPHEVGWIG----
Mvan_5109|M.vanbaalenii_PYR-1       VAAGVRPAGVWAYEAHRVA----ARRPRLGVDTDERTIPHEVGWIGG-PG
Mflv_1638|M.gilvum_PYR-GCK          VAAGVRPAGLWAYEAHRVA----AQRPRLGIDTDERTIPHEVGWIGG-PG
MSMEG_5796|M.smegmatis_MC2_155      VSAGVRPAGMWAYEAHRVA----AQRPRLGVDTDERTIPHEVGWIGG-PG
MAB_0730c|M.abscessus_ATCC_199      ERLGVRPAGLWAFEALRVA----ATRPRLTLDTDERTIPHEVGWIAIGDD
                                       *** .*:*::** ***    * **** :***:**********.    

Mb0834c|M.bovis_AF2122/97           AGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQ-RPSTGDAVL
Rv0811c|M.tuberculosis_H37Rv        AGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQ-RPSTGDAVL
MLBr_02203|M.leprae_Br4923          EGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSVE-RTSTGDAVL
MMAR_4878|M.marinum_M               IGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGSTD-RPSTGDSVL
MUL_0420|M.ulcerans_Agy99           IGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSTD-RPSTGDSVL
MAV_0750|M.avium_104                QGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSVD-RPATGDPVQ
TH_0071|M.thermoresistible__bu      -AAVHLDKGCYRGQETVARVHNLGKPPRMLALLHLDGSTEDRPATGDPVL
Mvan_5109|M.vanbaalenii_PYR-1       VGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGASD-RPSTGDPLL
Mflv_1638|M.gilvum_PYR-GCK          VGAVHLDKGCYRGQETVARVHNLGKPPRMLVLVHLDGDGD-RPSPGDPLL
MSMEG_5796|M.smegmatis_MC2_155      VGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSSD-RPATGDPVL
MAB_0730c|M.abscessus_ATCC_199      PRAVHLAKGCYRGQETVARVHNLGKPPRALVLLHLDGSAD-RPAPGDEVA
                                      **** *************:***:*** *.*:***   : *.:.** : 

Mb0834c|M.bovis_AF2122/97           AGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTAL---VTGP-EAEVAA
Rv0811c|M.tuberculosis_H37Rv        AGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTAL---VTGP-EAEVAA
MLBr_02203|M.leprae_Br4923          ANSGAVGRLGTVVEHVDLGPVALALLKRGLPTDTELTIELEGPQDGSVAA
MMAR_4878|M.marinum_M               AGGRSVGRVGTVVDHVDLGPVALALVKRGLPADTAL---MTGA-EATIPA
MUL_0420|M.ulcerans_Agy99           AGERSVGRVGTVVDHVDLGPVALALAKRGLPADTAL---MTGA-EATIPA
MAV_0750|M.avium_104                AGGRAVGRLGTVVDHVDLGPIALALLKRGLPADTAL---ATGP-QAAVAA
TH_0071|M.thermoresistible__bu      AGGRAVGRLGTVIDHVDLGPIALALVKRGLPADTEL---VTGG-AVQIAA
Mvan_5109|M.vanbaalenii_PYR-1       AGGRTVGRLGTVVDHVDEGVIALALLKRGLPADTAL---TTGG-EVHAAA
Mflv_1638|M.gilvum_PYR-GCK          AGGRAVGRLGTVVDHVDEGVIALALVKRGLPVDTAL---TTGG-EVQVAA
MSMEG_5796|M.smegmatis_MC2_155      AGGRTVGRLGTVVDHVDDGPIALALVKRGLPAETEL---MTGG-SVEVPA
MAB_0730c|M.abscessus_ATCC_199      AAGRAVGRVGSVVDHVDLGPIALALVKRSVIEALANG-NPAPLTAGPSPA
                                    *   :***:*:*::**: * :**** **.:                  .*

Mb0834c|M.bovis_AF2122/97           VIDVDSLPPADDVGAGRRAVERLRGGIR----
Rv0811c|M.tuberculosis_H37Rv        VIDVDSLPPADDVGAGRRAVERLRGGIR----
MLBr_02203|M.leprae_Br4923          VIDPDSLPAADEIGVGRLAIERLRG--R----
MMAR_4878|M.marinum_M               LIDAQSLPPADEVGAGRLALDRLRGSAR----
MUL_0420|M.ulcerans_Agy99           LIDAQSLPPADEVGAGRLALDRLRGSAR----
MAV_0750|M.avium_104                VIDPDSLPAAEQIGAGRLAVERLRGGAG----
TH_0071|M.thermoresistible__bu      SIDADSVPDTDTGGAGRRAVERLRGRAQ----
Mvan_5109|M.vanbaalenii_PYR-1       TIDPDSMPPADGVGAGRLAVDRLRGGTA----
Mflv_1638|M.gilvum_PYR-GCK          AIDPDSVPPADVVGAGRLAIDRLRTGGREEP-
MSMEG_5796|M.smegmatis_MC2_155      SIDPDSLPPPDSVGAGRLAIERLRHG------
MAB_0730c|M.abscessus_ATCC_199      AVDLDLLPDLHAEQRGRDAVNRLRQGSGQPGG
                                     :* : :*  .    ** *::***