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MSAVPTPEGSPDAGAVWHYGDPLGEQRSAATDAVVIDRSHRAVLALTGKDRQGWLHNISSQHVSAQPDGT VTENLSLDMQGRVEDHWVQTELDGTTYLDTESWRGEPLAAYLRKMVFWSDVQIEPADLGVLSLLGPALAG DAVLSALGLSALPEEATAQPLPGGGFVRRVPSEGLELDVLVARETLDDWKQRLVSAGVRPAGMWAYEAHR VAAQRPRLGVDTDERTIPHEVGWIGGPGVGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSSDRP ATGDPVLAGGRTVGRLGTVVDHVDDGPIALALVKRGLPAETELMTGGSVEVPASIDPDSLPPPDSVGAGR LAIERLRHG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5796 | - | - | 100% (359) | glycine cleavage T-protein (aminomethyl transferase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0834c | - | 1e-152 | 72.75% (367) | hypothetical protein Mb0834c |
| M. gilvum PYR-GCK | Mflv_1638 | - | 1e-156 | 74.72% (356) | glycine cleavage T protein (aminomethyl transferase) |
| M. tuberculosis H37Rv | Rv0811c | - | 1e-152 | 72.75% (367) | hypothetical protein Rv0811c |
| M. leprae Br4923 | MLBr_02203 | - | 1e-146 | 70.22% (366) | hypothetical protein MLBr_02203 |
| M. abscessus ATCC 19977 | MAB_0730c | - | 1e-118 | 62.97% (370) | hypothetical protein MAB_0730c |
| M. marinum M | MMAR_4878 | - | 1e-162 | 75.49% (359) | hypothetical protein MMAR_4878 |
| M. avium 104 | MAV_0750 | - | 1e-153 | 74.93% (359) | glycine cleavage T-protein (aminomethyl transferase) |
| M. thermoresistible (build 8) | TH_0071 | - | 1e-153 | 72.91% (358) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_0420 | - | 1e-160 | 74.65% (359) | hypothetical protein MUL_0420 |
| M. vanbaalenii PYR-1 | Mvan_5109 | - | 1e-166 | 77.72% (359) | glycine cleavage T protein (aminomethyl transferase) |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1638|M.gilvum_PYR-GCK MALETAKVPVPD-GPDAGAAWHYGDPLGEQRAAADGAVIVDRSHRAVLTL
Mvan_5109|M.vanbaalenii_PYR-1 ----MSAVPAPDIGPDAGAVWHYGDPLGEQRAAAQGAVVVDRSHRAVLSL
MSMEG_5796|M.smegmatis_MC2_155 ----MSAVPTPEGSPDAGAVWHYGDPLGEQRSAATDAVVIDRSHRAVLAL
Mb0834c|M.bovis_AF2122/97 ----MAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTL
Rv0811c|M.tuberculosis_H37Rv ----MAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTL
MLBr_02203|M.leprae_Br4923 ----MNAVLAPDPGPDAGAIWHFGDPLGEQRSAETDAVLVDRSHRATLTL
MMAR_4878|M.marinum_M ----MSAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTL
MUL_0420|M.ulcerans_Agy99 ----MSAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTL
MAV_0750|M.avium_104 ---MTHPVPAPDTGPDAGAVWHYGDPLGEQRAAETEALVIDRSHRGVLTL
TH_0071|M.thermoresistible__bu ----MSAVPSPESGPDAGTVWHHGDPFGEQRAATTEVVVVDRSHRAALTL
MAB_0730c|M.abscessus_ATCC_199 ----MTAVYVPEGNPDAGAVWHYGDPLGEQRAALTHAVLIDRSTRAVLAL
* *: .****: **.***:****:. .:::*** *..*:*
Mflv_1638|M.gilvum_PYR-GCK TGGERKSWLHTISSQHVSELPDGAVTENLSLDGQGRIEDHWVQTELNGRT
Mvan_5109|M.vanbaalenii_PYR-1 TGAERNSWLHTISSQHVSDLADGTVTENLSLDGQGRVEDHWVQTQLDGRT
MSMEG_5796|M.smegmatis_MC2_155 TGKDRQGWLHNISSQHVSAQPDGTVTENLSLDMQGRVEDHWVQTELDGTT
Mb0834c|M.bovis_AF2122/97 DGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTT
Rv0811c|M.tuberculosis_H37Rv DGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTT
MLBr_02203|M.leprae_Br4923 IGSDRQTWLHSISTQHVSALPDGASTQNLSLDSQGRVEDHWIQTELGGTT
MMAR_4878|M.marinum_M TGKDRQSWLHNISTQHVSELPEGASTQNLSLDGQGRVEDHWIQTELGATT
MUL_0420|M.ulcerans_Agy99 TGKDRQSWLHNISTQHVSELPEGASTQNLSLDGQGRVEDHWIQTELGATT
MAV_0750|M.avium_104 TGADRQTWLHSISTQYVSDLPEGASTQNLSLDGQGRVEDHWIQTELAGTT
TH_0071|M.thermoresistible__bu TGGDRKSWLHSLSTQHVSELPDGAVTENLSLDAQGRVEDHWIQTELPGVT
MAB_0730c|M.abscessus_ATCC_199 SGPERLSWLHTVSSQHVADLRHGQTRENLSLDGQGRVEDHWVQTDLDGIT
* :* ***.:*:*:*: .* :***** ***:****:**:* . *
Mflv_1638|M.gilvum_PYR-GCK VIDTEPARGEALESFLRKMVFWSDVAIESSDLAVLSLLGPGVADPAVLTA
Mvan_5109|M.vanbaalenii_PYR-1 VLDTEPWRGEPLLSFLRKMVFWADVVVEPADLGVLSLLGPGLTDPAVLDA
MSMEG_5796|M.smegmatis_MC2_155 YLDTESWRGEPLAAYLRKMVFWSDVQIEPADLGVLSLLGPALAGDAVLSA
Mb0834c|M.bovis_AF2122/97 YLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDA
Rv0811c|M.tuberculosis_H37Rv YLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDA
MLBr_02203|M.leprae_Br4923 YLDTEPWRGEPLLEYLRKMVFWSEVTPGSADMAMLSLLGPRLTEQAVHNA
MMAR_4878|M.marinum_M YLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQAVLDA
MUL_0420|M.ulcerans_Agy99 YLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQAVLDA
MAV_0750|M.avium_104 YLDTEPWRAGPLLDYLRKMVFWSDVTPAAADLAVLSLLGPKLAERAVLDA
TH_0071|M.thermoresistible__bu HLDTEPWRGEPLLTYLRKMVFWSEVTVEPADLGVLSLLGPRAVDPALLET
MAB_0730c|M.abscessus_ATCC_199 YLDTESWRGQPLKDFLTKMVFWSKVEVAAADLKVFTLLGPDTAG--LAEK
:***. *. .* :* *****: * .:*: :::*:** :
Mflv_1638|M.gilvum_PYR-GCK LGLDALPPEGTAVELADGGYVRRLP---GSEVEVDLVVPRPEVTRWFDAL
Mvan_5109|M.vanbaalenii_PYR-1 VGLPALPAPNSAVELPGGGFIRRLP---GPAVEVDVVVPRDELAAWRDRL
MSMEG_5796|M.smegmatis_MC2_155 LGLSALPEEATAQPLPGGGFVRRVP---SEGLELDVLVARETLDDWKQRL
Mb0834c|M.bovis_AF2122/97 LGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRL
Rv0811c|M.tuberculosis_H37Rv LGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRL
MLBr_02203|M.leprae_Br4923 LYLDALPDESTAVPLTAGSFVRRIPGAPAGQIELDLLVPRRESADWQSRL
MMAR_4878|M.marinum_M LGLDALPADLMAVPLPGGGFARRMP-SSAGQIELDLLVPRGDTADWKHRL
MUL_0420|M.ulcerans_Agy99 LGLDALPADLMAVPLPGGGFARRMP-SSAGQIELDLLVPRDGTADWKHRL
MAV_0750|M.avium_104 LGVDALPAEAAAVPTRGG-FLRRMPAGPAGRLELDLVVPRAEAADWRNRL
TH_0071|M.thermoresistible__bu VGAPPPPDGADAAPLPDGGFVRRLP---GRDTELDLVVPRAQVADWLDRL
MAB_0730c|M.abscessus_ATCC_199 LGIAALPELDNAVALPDGGLIRRVP-WPLAEATYDLLVPSG-----KGLA
: * * * **:* *::*
Mflv_1638|M.gilvum_PYR-GCK VAAGVRPAGLWAYEAHRVA----AQRPRLGIDTDERTIPHEVGWIGG-PG
Mvan_5109|M.vanbaalenii_PYR-1 VAAGVRPAGVWAYEAHRVA----ARRPRLGVDTDERTIPHEVGWIGG-PG
MSMEG_5796|M.smegmatis_MC2_155 VSAGVRPAGMWAYEAHRVA----AQRPRLGVDTDERTIPHEVGWIGG-PG
Mb0834c|M.bovis_AF2122/97 TQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGG-PG
Rv0811c|M.tuberculosis_H37Rv TQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGG-PG
MLBr_02203|M.leprae_Br4923 AGVGVRSAGMWAYEAHRVA----ALRPRLGVDTDQRTIPHEVGWIGG-PG
MMAR_4878|M.marinum_M TQAGVRPAGIWTYEAHRVA----AKRPRLGVDTDERTIPHEVGWIGG-PG
MUL_0420|M.ulcerans_Agy99 TQAGVRPAGIWTYEAHRVA----AKRPRLGVDTDERTIPHEVGWIGG-PG
MAV_0750|M.avium_104 AQAGVRPGGVWAYEAHRVA----ARRPRLGVDTDERTIPHEVGWIGG-PG
TH_0071|M.thermoresistible__bu TGAGVRRAGVWAYEALRVA----AVRPRLGVDTDERTIPHEVGWIG----
MAB_0730c|M.abscessus_ATCC_199 ERLGVRPAGLWAFEALRVA----ATRPRLTLDTDERTIPHEVGWIAIGDD
*** .*:*::** *** * **** :***:**********.
Mflv_1638|M.gilvum_PYR-GCK VGAVHLDKGCYRGQETVARVHNLGKPPRMLVLVHLDGDGD-RPSPGDPLL
Mvan_5109|M.vanbaalenii_PYR-1 VGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGASD-RPSTGDPLL
MSMEG_5796|M.smegmatis_MC2_155 VGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSSD-RPATGDPVL
Mb0834c|M.bovis_AF2122/97 AGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQ-RPSTGDAVL
Rv0811c|M.tuberculosis_H37Rv AGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQ-RPSTGDAVL
MLBr_02203|M.leprae_Br4923 EGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSVE-RTSTGDAVL
MMAR_4878|M.marinum_M IGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGSTD-RPSTGDSVL
MUL_0420|M.ulcerans_Agy99 IGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSTD-RPSTGDSVL
MAV_0750|M.avium_104 QGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSVD-RPATGDPVQ
TH_0071|M.thermoresistible__bu -AAVHLDKGCYRGQETVARVHNLGKPPRMLALLHLDGSTEDRPATGDPVL
MAB_0730c|M.abscessus_ATCC_199 PRAVHLAKGCYRGQETVARVHNLGKPPRALVLLHLDGSAD-RPAPGDEVA
**** *************:***:*** *.*:*** : *.:.** :
Mflv_1638|M.gilvum_PYR-GCK AGGRAVGRLGTVVDHVDEGVIALALVKRGLPVDTAL---TTGG-EVQVAA
Mvan_5109|M.vanbaalenii_PYR-1 AGGRTVGRLGTVVDHVDEGVIALALLKRGLPADTAL---TTGG-EVHAAA
MSMEG_5796|M.smegmatis_MC2_155 AGGRTVGRLGTVVDHVDDGPIALALVKRGLPAETEL---MTGG-SVEVPA
Mb0834c|M.bovis_AF2122/97 AGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTAL---VTGP-EAEVAA
Rv0811c|M.tuberculosis_H37Rv AGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTAL---VTGP-EAEVAA
MLBr_02203|M.leprae_Br4923 ANSGAVGRLGTVVEHVDLGPVALALLKRGLPTDTELTIELEGPQDGSVAA
MMAR_4878|M.marinum_M AGGRSVGRVGTVVDHVDLGPVALALVKRGLPADTAL---MTGA-EATIPA
MUL_0420|M.ulcerans_Agy99 AGERSVGRVGTVVDHVDLGPVALALAKRGLPADTAL---MTGA-EATIPA
MAV_0750|M.avium_104 AGGRAVGRLGTVVDHVDLGPIALALLKRGLPADTAL---ATGP-QAAVAA
TH_0071|M.thermoresistible__bu AGGRAVGRLGTVIDHVDLGPIALALVKRGLPADTEL---VTGG-AVQIAA
MAB_0730c|M.abscessus_ATCC_199 AAGRAVGRVGSVVDHVDLGPIALALVKRSVIEALANG-NPAPLTAGPSPA
* :***:*:*::**: * :**** **.: .*
Mflv_1638|M.gilvum_PYR-GCK AIDPDSVPPADVVGAGRLAIDRLRTGGREEP-
Mvan_5109|M.vanbaalenii_PYR-1 TIDPDSMPPADGVGAGRLAVDRLRGGTA----
MSMEG_5796|M.smegmatis_MC2_155 SIDPDSLPPPDSVGAGRLAIERLRHG------
Mb0834c|M.bovis_AF2122/97 VIDVDSLPPADDVGAGRRAVERLRGGIR----
Rv0811c|M.tuberculosis_H37Rv VIDVDSLPPADDVGAGRRAVERLRGGIR----
MLBr_02203|M.leprae_Br4923 VIDPDSLPAADEIGVGRLAIERLRG--R----
MMAR_4878|M.marinum_M LIDAQSLPPADEVGAGRLALDRLRGSAR----
MUL_0420|M.ulcerans_Agy99 LIDAQSLPPADEVGAGRLALDRLRGSAR----
MAV_0750|M.avium_104 VIDPDSLPAAEQIGAGRLAVERLRGGAG----
TH_0071|M.thermoresistible__bu SIDADSVPDTDTGGAGRRAVERLRGRAQ----
MAB_0730c|M.abscessus_ATCC_199 AVDLDLLPDLHAEQRGRDAVNRLRQGSGQPGG
:* : :* . ** *::***