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SAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTLTGKDRQSWLHNISTQHVSELPEGAS TQNLSLDGQGRVEDHWIQTELGATTYLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQ AVLDALGLDALPADLMAVPLPGGGFARRMPSSAGQIELDLLVPRDGTADWKHRLTQAGVRPAGIWTYEAH RVAAKRPRLGVDTDERTIPHEVGWIGGPGIGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSTDR PSTGDSVLAGERSVGRVGTVVDHVDLGPVALALAKRGLPADTALMTGAEATIPALIDAQSLPPADEVGAG RLALDRLRGSAR*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. ulcerans Agy99 | MUL_0420 | - | - | 100% (363) | hypothetical protein MUL_0420 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0834c | - | 1e-172 | 79.35% (368) | hypothetical protein Mb0834c |
M. gilvum PYR-GCK | Mflv_1638 | - | 1e-151 | 71.94% (360) | glycine cleavage T protein (aminomethyl transferase) |
M. tuberculosis H37Rv | Rv0811c | - | 1e-172 | 79.35% (368) | hypothetical protein Rv0811c |
M. leprae Br4923 | MLBr_02203 | - | 1e-162 | 76.44% (365) | hypothetical protein MLBr_02203 |
M. abscessus ATCC 19977 | MAB_0730c | - | 1e-113 | 59.18% (365) | hypothetical protein MAB_0730c |
M. marinum M | MMAR_4878 | - | 0.0 | 98.62% (363) | hypothetical protein MMAR_4878 |
M. avium 104 | MAV_0750 | - | 1e-168 | 78.33% (360) | glycine cleavage T-protein (aminomethyl transferase) |
M. smegmatis MC2 155 | MSMEG_5796 | - | 1e-160 | 74.65% (359) | glycine cleavage T-protein (aminomethyl transferase) |
M. thermoresistible (build 8) | TH_0071 | - | 1e-148 | 71.15% (364) | CONSERVED HYPOTHETICAL PROTEIN |
M. vanbaalenii PYR-1 | Mvan_5109 | - | 1e-161 | 75.83% (360) | glycine cleavage T protein (aminomethyl transferase) |
CLUSTAL 2.0.9 multiple sequence alignment MUL_0420|M.ulcerans_Agy99 ----MSAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTL MMAR_4878|M.marinum_M ----MSAVPAPDPGPDAGAIWHYGDPLGEQRAAETGAVLVDRSHRAVLTL Mb0834c|M.bovis_AF2122/97 ----MAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTL Rv0811c|M.tuberculosis_H37Rv ----MAAVPAPDPGPDAGAIWHYGDPLGEQRAGQADAVLVDRSHRAVLTL MLBr_02203|M.leprae_Br4923 ----MNAVLAPDPGPDAGAIWHFGDPLGEQRSAETDAVLVDRSHRATLTL MAV_0750|M.avium_104 ---MTHPVPAPDTGPDAGAVWHYGDPLGEQRAAETEALVIDRSHRGVLTL TH_0071|M.thermoresistible__bu ----MSAVPSPESGPDAGTVWHHGDPFGEQRAATTEVVVVDRSHRAALTL Mflv_1638|M.gilvum_PYR-GCK MALETAKVPVPD-GPDAGAAWHYGDPLGEQRAAADGAVIVDRSHRAVLTL Mvan_5109|M.vanbaalenii_PYR-1 ----MSAVPAPDIGPDAGAVWHYGDPLGEQRAAAQGAVVVDRSHRAVLSL MSMEG_5796|M.smegmatis_MC2_155 ----MSAVPTPEGSPDAGAVWHYGDPLGEQRSAATDAVVIDRSHRAVLAL MAB_0730c|M.abscessus_ATCC_199 ----MTAVYVPEGNPDAGAVWHYGDPLGEQRAALTHAVLIDRSTRAVLAL * *: .****: **.***:****:. .:::*** *..*:* MUL_0420|M.ulcerans_Agy99 TGKDRQSWLHNISTQHVSELPEGASTQNLSLDGQGRVEDHWIQTELGATT MMAR_4878|M.marinum_M TGKDRQSWLHNISTQHVSELPEGASTQNLSLDGQGRVEDHWIQTELGATT Mb0834c|M.bovis_AF2122/97 DGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTT Rv0811c|M.tuberculosis_H37Rv DGGDRQTWLHSISTQHVSDLPEGASTQNLSLDGQGRVEDHWIQTELGGTT MLBr_02203|M.leprae_Br4923 IGSDRQTWLHSISTQHVSALPDGASTQNLSLDSQGRVEDHWIQTELGGTT MAV_0750|M.avium_104 TGADRQTWLHSISTQYVSDLPEGASTQNLSLDGQGRVEDHWIQTELAGTT TH_0071|M.thermoresistible__bu TGGDRKSWLHSLSTQHVSELPDGAVTENLSLDAQGRVEDHWIQTELPGVT Mflv_1638|M.gilvum_PYR-GCK TGGERKSWLHTISSQHVSELPDGAVTENLSLDGQGRIEDHWVQTELNGRT Mvan_5109|M.vanbaalenii_PYR-1 TGAERNSWLHTISSQHVSDLADGTVTENLSLDGQGRVEDHWVQTQLDGRT MSMEG_5796|M.smegmatis_MC2_155 TGKDRQGWLHNISSQHVSAQPDGTVTENLSLDMQGRVEDHWVQTELDGTT MAB_0730c|M.abscessus_ATCC_199 SGPERLSWLHTVSSQHVADLRHGQTRENLSLDGQGRVEDHWVQTDLDGIT * :* ***.:*:*:*: .* :***** ***:****:**:* . * MUL_0420|M.ulcerans_Agy99 YLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQAVLDA MMAR_4878|M.marinum_M YLDTEPWRGEPLLNYLRKMVFWAEVTPDTADLAVLSLIGPQLSDQAVLDA Mb0834c|M.bovis_AF2122/97 YLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDA Rv0811c|M.tuberculosis_H37Rv YLDTEPWRGEPLLAYLRKMVFWSMVTPRAADMAVLSLLGPRLAEERVLDA MLBr_02203|M.leprae_Br4923 YLDTEPWRGEPLLEYLRKMVFWSEVTPGSADMAMLSLLGPRLTEQAVHNA MAV_0750|M.avium_104 YLDTEPWRAGPLLDYLRKMVFWSDVTPAAADLAVLSLLGPKLAERAVLDA TH_0071|M.thermoresistible__bu HLDTEPWRGEPLLTYLRKMVFWSEVTVEPADLGVLSLLGPRAVDPALLET Mflv_1638|M.gilvum_PYR-GCK VIDTEPARGEALESFLRKMVFWSDVAIESSDLAVLSLLGPGVADPAVLTA Mvan_5109|M.vanbaalenii_PYR-1 VLDTEPWRGEPLLSFLRKMVFWADVVVEPADLGVLSLLGPGLTDPAVLDA MSMEG_5796|M.smegmatis_MC2_155 YLDTESWRGEPLAAYLRKMVFWSDVQIEPADLGVLSLLGPALAGDAVLSA MAB_0730c|M.abscessus_ATCC_199 YLDTESWRGQPLKDFLTKMVFWSKVEVAAADLKVFTLLGPDTAG--LAEK :***. *. .* :* *****: * .:*: :::*:** : MUL_0420|M.ulcerans_Agy99 LGLDALPADLMAVPLPGGGFARRMP-SSAGQIELDLLVPRDGTADWKHRL MMAR_4878|M.marinum_M LGLDALPADLMAVPLPGGGFARRMP-SSAGQIELDLLVPRGDTADWKHRL Mb0834c|M.bovis_AF2122/97 LGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRL Rv0811c|M.tuberculosis_H37Rv LGLDVLPAEWLAVPLAGGGIVRRMPDGLAGQIELDVVVKRGDRADWQRRL MLBr_02203|M.leprae_Br4923 LYLDALPDESTAVPLTAGSFVRRIPGAPAGQIELDLLVPRRESADWQSRL MAV_0750|M.avium_104 LGVDALPAEAAAVPTRGG-FLRRMPAGPAGRLELDLVVPRAEAADWRNRL TH_0071|M.thermoresistible__bu VGAPPPPDGADAAPLPDGGFVRRLP---GRDTELDLVVPRAQVADWLDRL Mflv_1638|M.gilvum_PYR-GCK LGLDALPPEGTAVELADGGYVRRLP---GSEVEVDLVVPRPEVTRWFDAL Mvan_5109|M.vanbaalenii_PYR-1 VGLPALPAPNSAVELPGGGFIRRLP---GPAVEVDVVVPRDELAAWRDRL MSMEG_5796|M.smegmatis_MC2_155 LGLSALPEEATAQPLPGGGFVRRVP---SEGLELDVLVARETLDDWKQRL MAB_0730c|M.abscessus_ATCC_199 LGIAALPELDNAVALPDGGLIRRVP-WPLAEATYDLLVPSG-----KGLA : * * * **:* *::* MUL_0420|M.ulcerans_Agy99 TQAGVRPAGIWTYEAHRVA----AKRPRLGVDTDERTIPHEVGWIGG-PG MMAR_4878|M.marinum_M TQAGVRPAGIWTYEAHRVA----AKRPRLGVDTDERTIPHEVGWIGG-PG Mb0834c|M.bovis_AF2122/97 TQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGG-PG Rv0811c|M.tuberculosis_H37Rv TQAGVRPAGIWAYEAHRVAHRVPARRPRLGVDTDERTIPHEVGWIGG-PG MLBr_02203|M.leprae_Br4923 AGVGVRSAGMWAYEAHRVA----ALRPRLGVDTDQRTIPHEVGWIGG-PG MAV_0750|M.avium_104 AQAGVRPGGVWAYEAHRVA----ARRPRLGVDTDERTIPHEVGWIGG-PG TH_0071|M.thermoresistible__bu TGAGVRRAGVWAYEALRVA----AVRPRLGVDTDERTIPHEVGWIG---- Mflv_1638|M.gilvum_PYR-GCK VAAGVRPAGLWAYEAHRVA----AQRPRLGIDTDERTIPHEVGWIGG-PG Mvan_5109|M.vanbaalenii_PYR-1 VAAGVRPAGVWAYEAHRVA----ARRPRLGVDTDERTIPHEVGWIGG-PG MSMEG_5796|M.smegmatis_MC2_155 VSAGVRPAGMWAYEAHRVA----AQRPRLGVDTDERTIPHEVGWIGG-PG MAB_0730c|M.abscessus_ATCC_199 ERLGVRPAGLWAFEALRVA----ATRPRLTLDTDERTIPHEVGWIAIGDD *** .*:*::** *** * **** :***:**********. MUL_0420|M.ulcerans_Agy99 IGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSTD-RPSTGDSVL MMAR_4878|M.marinum_M IGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGSTD-RPSTGDSVL Mb0834c|M.bovis_AF2122/97 AGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQ-RPSTGDAVL Rv0811c|M.tuberculosis_H37Rv AGAVHLNKGCYRGQETVARVHNLGRPPRMLVLLHLDESVQ-RPSTGDAVL MLBr_02203|M.leprae_Br4923 EGAVHLDKGCYRGQETVARVQNLGKPPRMLVLLHLDGSVE-RTSTGDAVL MAV_0750|M.avium_104 QGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSVD-RPATGDPVQ TH_0071|M.thermoresistible__bu -AAVHLDKGCYRGQETVARVHNLGKPPRMLALLHLDGSTEDRPATGDPVL Mflv_1638|M.gilvum_PYR-GCK VGAVHLDKGCYRGQETVARVHNLGKPPRMLVLVHLDGDGD-RPSPGDPLL Mvan_5109|M.vanbaalenii_PYR-1 VGAVHLDKGCYRGQETVARVHNLGKPPRMLVLLHLDGASD-RPSTGDPLL MSMEG_5796|M.smegmatis_MC2_155 VGAVHLDKGCYRGQETVARVHNLGRPPRMLVLLHLDGSSD-RPATGDPVL MAB_0730c|M.abscessus_ATCC_199 PRAVHLAKGCYRGQETVARVHNLGKPPRALVLLHLDGSAD-RPAPGDEVA **** *************:***:*** *.*:*** : *.:.** : MUL_0420|M.ulcerans_Agy99 AGERSVGRVGTVVDHVDLGPVALALAKRGLPADTAL---MTGA-EATIPA MMAR_4878|M.marinum_M AGGRSVGRVGTVVDHVDLGPVALALVKRGLPADTAL---MTGA-EATIPA Mb0834c|M.bovis_AF2122/97 AGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTAL---VTGP-EAEVAA Rv0811c|M.tuberculosis_H37Rv AGGRTVGRLGTVVEHVELGPVALALLKRGLPGDTAL---VTGP-EAEVAA MLBr_02203|M.leprae_Br4923 ANSGAVGRLGTVVEHVDLGPVALALLKRGLPTDTELTIELEGPQDGSVAA MAV_0750|M.avium_104 AGGRAVGRLGTVVDHVDLGPIALALLKRGLPADTAL---ATGP-QAAVAA TH_0071|M.thermoresistible__bu AGGRAVGRLGTVIDHVDLGPIALALVKRGLPADTEL---VTGG-AVQIAA Mflv_1638|M.gilvum_PYR-GCK AGGRAVGRLGTVVDHVDEGVIALALVKRGLPVDTAL---TTGG-EVQVAA Mvan_5109|M.vanbaalenii_PYR-1 AGGRTVGRLGTVVDHVDEGVIALALLKRGLPADTAL---TTGG-EVHAAA MSMEG_5796|M.smegmatis_MC2_155 AGGRTVGRLGTVVDHVDDGPIALALVKRGLPAETEL---MTGG-SVEVPA MAB_0730c|M.abscessus_ATCC_199 AAGRAVGRVGSVVDHVDLGPIALALVKRSVIEALANG-NPAPLTAGPSPA * :***:*:*::**: * :**** **.: .* MUL_0420|M.ulcerans_Agy99 LIDAQSLPPADEVGAGRLALDRLRGSAR---- MMAR_4878|M.marinum_M LIDAQSLPPADEVGAGRLALDRLRGSAR---- Mb0834c|M.bovis_AF2122/97 VIDVDSLPPADDVGAGRRAVERLRGGIR---- Rv0811c|M.tuberculosis_H37Rv VIDVDSLPPADDVGAGRRAVERLRGGIR---- MLBr_02203|M.leprae_Br4923 VIDPDSLPAADEIGVGRLAIERLRG--R---- MAV_0750|M.avium_104 VIDPDSLPAAEQIGAGRLAVERLRGGAG---- TH_0071|M.thermoresistible__bu SIDADSVPDTDTGGAGRRAVERLRGRAQ---- Mflv_1638|M.gilvum_PYR-GCK AIDPDSVPPADVVGAGRLAIDRLRTGGREEP- Mvan_5109|M.vanbaalenii_PYR-1 TIDPDSMPPADGVGAGRLAVDRLRGGTA---- MSMEG_5796|M.smegmatis_MC2_155 SIDPDSLPPPDSVGAGRLAIERLRHG------ MAB_0730c|M.abscessus_ATCC_199 AVDLDLLPDLHAEQRGRDAVNRLRQGSGQPGG :* : :* . ** *::***