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IGGGDSMRTRCRAGRSTGESAVAGGSEVVAGTVVDPARDERRAVRVGVVFGLMALAAVVVIAGWLKFQVH AADEELQQRAQLLAAGRDGAVLLTTINHSDAEAKVEQILESATGVFLEDFRSRSQSFLATVRRAQSDTAG TVVEAGLESSHGDQANVLVVMSVKTSLAGTAAPPRLWRMRIGVQQVGQSTKVSDVEFLP*
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. vanbaalenii PYR-1 | Mvan_0919 | - | - | 100% (200) | hypothetical protein Mvan_0919 |
M. vanbaalenii PYR-1 | Mvan_4598 | - | 4e-36 | 41.27% (189) | hypothetical protein Mvan_4598 |
M. vanbaalenii PYR-1 | Mvan_0519 | - | 2e-34 | 42.19% (192) | hypothetical protein Mvan_0519 |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1398c | - | 1e-19 | 32.74% (168) | hypothetical protein Mb1398c |
M. gilvum PYR-GCK | Mflv_2107 | - | 9e-36 | 43.20% (169) | hypothetical protein Mflv_2107 |
M. tuberculosis H37Rv | Rv1972 | - | 1e-33 | 46.20% (171) | mce associated membrane protein |
M. leprae Br4923 | MLBr_02597 | - | 7e-06 | 25.78% (128) | hypothetical protein MLBr_02597 |
M. abscessus ATCC 19977 | MAB_1004c | - | 2e-06 | 27.33% (161) | hypothetical protein MAB_1004c |
M. marinum M | MMAR_4057 | - | 1e-33 | 45.86% (157) | Mce associated membrane protein |
M. avium 104 | MAV_2538 | - | 1e-36 | 46.06% (165) | hypothetical protein MAV_2538 |
M. smegmatis MC2 155 | MSMEG_0352 | - | 9e-32 | 42.42% (165) | hypothetical protein MSMEG_0352 |
M. thermoresistible (build 8) | TH_0481 | - | 5e-34 | 43.78% (185) | PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN |
M. ulcerans Agy99 | MUL_3924 | - | 1e-33 | 46.54% (159) | Mce associated membrane protein |
CLUSTAL 2.0.9 multiple sequence alignment Mvan_0919|M.vanbaalenii_PYR-1 ---------------------------MIGGGDSMRTRCRAGRST----- Rv1972|M.tuberculosis_H37Rv -------------------------------------MSVAVDSD----- MMAR_4057|M.marinum_M --------MSDSTTLEEQPEPAEVVEPEGESGQAGVPEAQPRDEDQDETA MUL_3924|M.ulcerans_Agy99 --------MSDSTTLEEQPEPAEVVEPEGESGQAGVPEAQPRDEDQDETA MAV_2538|M.avium_104 --------------------------------------MEARDDE----- Mflv_2107|M.gilvum_PYR-GCK --------MADDAAAPEG-------ELTDAQEREASTAAEPTDTDIDTED TH_0481|M.thermoresistible__bu --------MVDG----------------NVAGAEDVAEAEDVAEA----- MSMEG_0352|M.smegmatis_MC2_155 -----------------------------MAVDVDTARHELTQPGQ---- Mb1398c|M.bovis_AF2122/97 MAETTEPPSDAGTSQADAMALAAEAEAAEAEALAAAARARARAARLKREA MAB_1004c|M.abscessus_ATCC_199 ----------MVTMTKEDVDSTNDADTDTADDKETVDSAAETDSEI---- MLBr_02597|M.leprae_Br4923 -----------------------------------MSPRRKFQAG----- Mvan_0919|M.vanbaalenii_PYR-1 -------GESAVAG--------GSEVVAGTVVDPARDERR---------- Rv1972|M.tuberculosis_H37Rv -------AEDDAVS--------EIAEAAGVSPAPAKPSMS---------- MMAR_4057|M.marinum_M DETQDETQEDADADPEAGEDDAQASDGEQ--ESP-KPAPS---------- MUL_3924|M.ulcerans_Agy99 DET----QEDADADPEAGEDDAQASDGEQ--ESP-KPAPS---------- MAV_2538|M.avium_104 -------VEDYDAS----VDDAAEPDAED--PAPAKKLRS---------- Mflv_2107|M.gilvum_PYR-GCK -------TEDADAP-EAVEDDSVDADVDETDATPATGAMS---------- TH_0481|M.thermoresistible__bu --------EDVAEA----EDVAGAEDVAG-SASPSDDRRSF--------- MSMEG_0352|M.smegmatis_MC2_155 -------ADDQETD--------EKSGVDTDSREPTSAQVR---------- Mb1398c|M.bovis_AF2122/97 LAMAPAEDENVPEEYADWEDAEDYDDYDDYEAADQEAARSASWRRRLRVR MAB_1004c|M.abscessus_ATCC_199 -------AEDAASTDTDAASSADSDSETASSDEDGDAAKG---------- MLBr_02597|M.leprae_Br4923 -----------------------EGLLLVSHTVASQRRWG---------- Mvan_0919|M.vanbaalenii_PYR-1 AVRVGVVFGLMALAAVVV---IAGWLKFQVHAADEELQQRAQLLAAGRDG Rv1972|M.tuberculosis_H37Rv APRRMLLFGLVVVVALAV---LLCCWGFRVQRARHAQDQRGHFLQAARQC MMAR_4057|M.marinum_M KVRLAIVVGLAAVVAMAA---LASWFGFHAYQSHQADQQRKLYVQVARQG MUL_3924|M.ulcerans_Agy99 KVRLAIVVGLAAVVAMAA---LASWFGFHAYQSHQADQQRKLYVQVARQG MAV_2538|M.avium_104 PALLATVFGLVTVVGLAA---LGGWFGYQTYQSHQAQQQRELMVRIGRQG Mflv_2107|M.gilvum_PYR-GCK HIKLALIAGLVGVLALAG---LAGWLGYQTYESHQAEEQRNLFVQVGRQG TH_0481|M.thermoresistible__bu PAGWVLLAGGLGVLALCLT--LVGWLGYRAYDSRVDEAQRQLFLQVGRQA MSMEG_0352|M.smegmatis_MC2_155 GVRGALVIGVLLLAIVGG---ATGWLVWQTQRAEQDQRMNEMLLQAGREA Mb1398c|M.bovis_AF2122/97 LPRLSTIAMAAAVVIICGFTGLSGYIVWQHHEATERQQRAAAFAAGAKQG MAB_1004c|M.abscessus_ATCC_199 ASWVRYAALGAVAAIMVGALVFSGIFGWKVWQQHQIDAAGEQALAVAIPY MLBr_02597|M.leprae_Br4923 LPLAATFAALVMVAAITA----STLMSISHASRELAVAKDQQVLSYVKWF : Mvan_0919|M.vanbaalenii_PYR-1 AVLLTTINHSDAEAKVEQILESATGVFLEDFRSRSQSFLATVRRAQSDTA Rv1972|M.tuberculosis_H37Rv ALNLTTIDWRNAEADVRRILDGATGEFYNDFAQRSQPFVEVLRHAKASTV MMAR_4057|M.marinum_M AINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIQVVQHFQSKSV MUL_3924|M.ulcerans_Agy99 AINLTTIDWEHVDADIERILNSATGTFYDDFQRRSKPFIKVVQHFQSKSV MAV_2538|M.avium_104 ALNLTTIDWQHADADVQRILDSATGTFYDDFSHRSKPFIDVVKKAQSKSV Mflv_2107|M.gilvum_PYR-GCK ALNLTTINWESAEADVQRILDSATGTFYDDFQQRAEPFVQVVKQAQSKSE TH_0481|M.thermoresistible__bu AINLTTIDHTRAEADVQRIIDGSTGGFREDFESRSAPFIEVVRQAESKSE MSMEG_0352|M.smegmatis_MC2_155 AVNLTTMDFEHIREDIQRVLDGSTGTFYDEFEQRAPAFEEVVTKTQSKTE Mb1398c|M.bovis_AF2122/97 VINMNSLDFNKAKEDVARVIDSSTGEFRDDFQQRAADFTKVVEQSKVVTE MAB_1004c|M.abscessus_ATCC_199 TETLTSIDSNDIDESFRKILNGATGDLKKDFTPASVQLRQLLLDNKAASH MLBr_02597|M.leprae_Br4923 MTQFTTLDPYHANDYVARILAQATGDFAKQYNEKVNEILLQVAQAEPAT- :.::: . ::: :** : .:: : : : : Mvan_0919|M.vanbaalenii_PYR-1 GTVVEAGLESSHGD-QANVLVVMSVKTSLAGTAAP-PRLWRMRIGVQQVG Rv1972|M.tuberculosis_H37Rv GTITEAGLQTQTAD-TAQALVAVSVQTSNAGEADPVPRAWRMRITVQRVG MMAR_4057|M.marinum_M GTITAAALESESDD-AAQVLVAVSVKTTTAGAPEQRPRAWRMRITVQQVG MUL_3924|M.ulcerans_Agy99 GTITAAALESESDD-AAQVLVAVSVKTTTAAAPEQRPRAWRMRITVQQVG MAV_2538|M.avium_104 GTITEAGLESQSGS-EAQVLVAVSVKTSNLGAAEQDPRHWRMRVIVQKVG Mflv_2107|M.gilvum_PYR-GCK GTIAEAGLESATDS-EGQVLVAVTVRTTNAGTPEQQPRAWRMRISVQEID TH_0481|M.thermoresistible__bu GTVTEAGLESMDDD-EGQVLVAVSVRTTTPADPEPQPRSWRMRITVQKDH MSMEG_0352|M.smegmatis_MC2_155 GTVTEAGIESVSAD-SARVLVAVSVKTSNIAAPEQRPRLWRMRIDVQRVG Mb1398c|M.bovis_AF2122/97 GTVNATAVESMNEH-SAVVLVAATSRVTNSAGAKDEPRAWRLKVTVTEEG MAB_1004c|M.abscessus_ATCC_199 GKVVNSAIQYKSTN-KVVLLMMVDQSITNTQRPDPRVDKSRMKITMEKID MLBr_02597|M.leprae_Br4923 GTVLDAGVERWNDDGSANVLVATEVTSKSPDEKQVLENTNRWTATATREG *.: :.:: *: . * . Mvan_0919|M.vanbaalenii_PYR-1 QSTKVSDVEFLP Rv1972|M.tuberculosis_H37Rv DRVKVSDVGFVP MMAR_4057|M.marinum_M DEAKVANVEFVP MUL_3924|M.ulcerans_Agy99 DEAKVANVEFVP MAV_2538|M.avium_104 NDMKVSNVAFVP Mflv_2107|M.gilvum_PYR-GCK GDAKVSNVEFVP TH_0481|M.thermoresistible__bu DEAKVSNVEFVP MSMEG_0352|M.smegmatis_MC2_155 DVAKVTNVGFVA Mb1398c|M.bovis_AF2122/97 GQYKMSKVEFVP MAB_1004c|M.abscessus_ATCC_199 GRWLASKLEYL- MLBr_02597|M.leprae_Br4923 NQWKISNLLQVI :.: :