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KVMAQMAMVMNLDKCIGCHTCSVTCKQAWTNRPGTEYVWFNNVETRPGQGYPRTYQDQERWRGGWIRDKR GRLRLRGGGRLNKLLNIFSNPKLPSINDYYEPWTYDYENLTNAPLGEHMPVAPPRSLISGKPMKVEWSAN WDDDLGGSPEIVPGDPVLAKVSEEIRLELEQTFMFYLPRICEHCLNPSCVASCPSGAMYKRTEDGIVLVD QDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYPRIEVGLPTVCSETCVGRLRYLGLVLYDVDRVTAA ASVENDTDLYEAQKSILLDPSDPEVIAGARAEGISDEWIEAAQRSPIYALIHEYQVALPLHPEYRTMPMV WYIPPLSPVVDAVSRDGHDGEDAGNLFGALEALRIPIEYLAGLFTAGDTAVVEGVLRRLAAMRSYMRDVN LGRETQPHIPESVGMTEEQIYEMYRLLALAKYDERYVIPTAYAAVEPWSLEEPGCSLSFEGGPGMYESGP FGEASGQPIPVAVETFHALRQRQTSEHMAADEARPSRVNLLNWDGRGAPSGLFPQDGDR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4545 | - | - | 100% (550) | nitrate reductase, beta subunit |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1194 | narH | 0.0 | 82.03% (551) | respiratory nitrate reductase subunit beta NarH |
| M. gilvum PYR-GCK | Mflv_2157 | - | 0.0 | 92.00% (550) | nitrate reductase, beta subunit |
| M. tuberculosis H37Rv | Rv1162 | narH | 0.0 | 82.03% (551) | respiratory nitrate reductase subunit beta NarH |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | - | - | - | - | - |
| M. marinum M | MMAR_5196 | hybA | 3e-18 | 46.91% (81) | Fe-S-cluster-containing hydrogenase, HybA |
| M. avium 104 | MAV_1304 | narH | 0.0 | 81.32% (546) | nitrate reductase, beta subunit |
| M. smegmatis MC2 155 | MSMEG_5139 | narH | 0.0 | 86.11% (547) | nitrate reductase, beta subunit |
| M. thermoresistible (build 8) | TH_1884 | narH | 0.0 | 86.35% (542) | PROBABLE RESPIRATORY NITRATE REDUCTASE (BETA CHAIN) NARH |
| M. ulcerans Agy99 | - | - | - | - | - |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1194|M.bovis_AF2122/97 MKVMAQMAMVMNLDKCIGCHTCSVTCKQAWTNRSGTEYVWFNNVETRPGV
Rv1162|M.tuberculosis_H37Rv MKVMAQMAMVMNLDKCIGCHTCSVTCKQAWTNRSGTEYVWFNNVETRPGV
MAV_1304|M.avium_104 MKVMAQLAMVMNLDKCIGCHTCSVTCKQAWTNRSGTEYVWFNNVETRPGQ
Mvan_4545|M.vanbaalenii_PYR-1 MKVMAQMAMVMNLDKCIGCHTCSVTCKQAWTNRPGTEYVWFNNVETRPGQ
Mflv_2157|M.gilvum_PYR-GCK MKVMAQVAMVMNLDKCIGCHTCSVTCKQAWTNRPGTEYVWFNNVETRPGQ
MSMEG_5139|M.smegmatis_MC2_155 MKVMAQMAMVMNLDKCIGCHTCSVTCKQAWTNRAGTEYVWFNNVETRPGQ
TH_1884|M.thermoresistible__bu ---MTQLAMVMNLDKCIGCHTCSVTCKQAWTNRPGTEYVWFNNVETRPGQ
MMAR_5196|M.marinum_M ---MSSNSFYGPLDDPAG--------DAGYTDHP-PRVGFFT--DTSICI
*:. :: **. * . .:*::. .. :*. :*
Mb1194|M.bovis_AF2122/97 GYPRTYEDQERWRGGWVRDKKGRLRLRDGGRIHKLLRIFANPKLPTIGDY
Rv1162|M.tuberculosis_H37Rv GYPRTYEDQERWRGGWVRDKKGRLRLRDGGRIHKLLRIFANPKLPTIGDY
MAV_1304|M.avium_104 GYPRTYEDQERWRGGWIRDKRGRLRLRDGGRFQKLLRIFANPKLPVIGDY
Mvan_4545|M.vanbaalenii_PYR-1 GYPRTYQDQERWRGGWIRDKRGRLRLRGGGRLNKLLNIFSNPKLPSINDY
Mflv_2157|M.gilvum_PYR-GCK GYPRTYQDQERWRGGWVRDKRGRLKLRGGGRLNKLLNIFSNPKMPSIDDY
MSMEG_5139|M.smegmatis_MC2_155 GYPRTYEDQEKWRGGWRLDGRGRLRLRDGGRLAKLARIFANPKLPSIDDY
TH_1884|M.thermoresistible__bu GYPRTYEDQERWRGGWVRDRRGRLRLRDGGRFAKLLRIFANPKMPSINDY
MMAR_5196|M.marinum_M GCKACEVACKEWN-----------EVPDDG-FNLLGMSFDNTGMLGASTW
* :.*. .: ..* : * * *. : . :
Mb1194|M.bovis_AF2122/97 YEPWTYDYENLTSAPAGDTFPTAAPRSLISGNPMKVSWGSNWDDNLAGSP
Rv1162|M.tuberculosis_H37Rv YEPWTYDYENLTSAPAGDTFPTAAPRSLISGNPMKVSWGSNWDDNLAGSP
MAV_1304|M.avium_104 YEPWTYEYENLTTAPAGDTFPTAAPKSLISGEPMKVSWGPNWDDNLAGSP
Mvan_4545|M.vanbaalenii_PYR-1 YEPWTYDYENLTNAPLGEHMPVAPPRSLISGKPMKVEWSANWDDDLGGSP
Mflv_2157|M.gilvum_PYR-GCK YEPWTYDYENLINAPLGDQMPVAPPRSLITGEPMKVEWSANWDDNLGGST
MSMEG_5139|M.smegmatis_MC2_155 YEPWTYDYENLTSAPLGEHMPVAPPRSLIDGKPMKVSWSAAWDDDLGGSQ
TH_1884|M.thermoresistible__bu YEPWTYDYDNLLSAPLGDQMPVAPPRSLISGAPMTIEWSANWDDDLGGSP
MMAR_5196|M.marinum_M RH---VAFIEQARPPVDLGVPKFERPGQASGPQDRTDFR-----------
. : : .* . .* . * .:
Mb1194|M.bovis_AF2122/97 EIVPNDPVLKKVNQVNQEVKLKLEETFMFYLPRICEHCLNPSCVASCPSG
Rv1162|M.tuberculosis_H37Rv EIVPNDPVLKKVNQVNQEVKLKLEETFMFYLPRICEHCLNPSCVASCPSG
MAV_1304|M.avium_104 EILAEDPILKKVS---EEVKLSLEQTFMFYLPRICEHCLNPSCVASCPSG
Mvan_4545|M.vanbaalenii_PYR-1 EIVPGDPVLAKVS---EEIRLELEQTFMFYLPRICEHCLNPSCVASCPSG
Mflv_2157|M.gilvum_PYR-GCK EILSGDPILEKVS---ETVRLELEQTFMFYLPRICEHCLNPSCVASCPSG
MSMEG_5139|M.smegmatis_MC2_155 EIAPGDPVLQKVS---EHIKLEFEQTFMFYLPRICEHCLNPSCVASCPSG
TH_1884|M.thermoresistible__bu EIVPDDPVLKKVN---EQVKLELEQTFMFYLPRICEHCLNPSCVASCPSG
MMAR_5196|M.marinum_M ---------------------------WLMSSDVCKHCTHAGCLDVCPTG
: . :*:** :..*: **:*
Mb1194|M.bovis_AF2122/97 AMYKRTEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYP
Rv1162|M.tuberculosis_H37Rv AMYKRTEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYP
MAV_1304|M.avium_104 AMYKRSEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYP
Mvan_4545|M.vanbaalenii_PYR-1 AMYKRTEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYP
Mflv_2157|M.gilvum_PYR-GCK AMYKRSEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYP
MSMEG_5139|M.smegmatis_MC2_155 AMYKRSEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTLCYP
TH_1884|M.thermoresistible__bu ALYKRSEDGIVLVDQDRCRGWRMCVSGCPYKKVYFNHKTGKAEKCTFCYP
MMAR_5196|M.marinum_M ALFR-TEFGTVVVQQDICNGCGYCVSGCPYGVIERREGDGRAWKCTLCYD
*::: :* * *:*:** *.* ******* : .. *:* ***:**
Mb1194|M.bovis_AF2122/97 RIEVGLPTVCSETCVGRLRYLGLVLYDVDQVLQAASVESDTDLYEAQRRI
Rv1162|M.tuberculosis_H37Rv RIEVGLPTVCSETCVGRLRYLGLVLYDVDQVLQAASVESDTDLYEAQRRI
MAV_1304|M.avium_104 RMEVGLPTICSETCVGRLRYLGVVLYDMDRVLEAASVENDTDLYRAQCDI
Mvan_4545|M.vanbaalenii_PYR-1 RIEVGLPTVCSETCVGRLRYLGLVLYDVDRVTAAASVENDTDLYEAQKSI
Mflv_2157|M.gilvum_PYR-GCK RIEVGLPTVCSETCVGRLRYLGVVLYDVDRVTEAASVEKDTDLYEAHRSI
MSMEG_5139|M.smegmatis_MC2_155 RIEVGMPTVCSETCVGRLRYLGLVLYDVDRVLEAASVPDETDLYEAHRQI
TH_1884|M.thermoresistible__bu RVEVGLPTVCSETCVGRLRYIGLVLYDADAVTAAASVEKETDLYEAQKAL
MMAR_5196|M.marinum_M RLRDGLEPACAKACPTNSIQFGPLEELRERAARRVEQLHDRGVPEAR---
*:. *: . *:::* . :* : : . .. : .: .*:
Mb1194|M.bovis_AF2122/97 LLDPHDPRVIAGARAEGIADEWIEAAQRSPVYALINTYRVALPLHPEYRT
Rv1162|M.tuberculosis_H37Rv LLDPHDPRVIAGARAEGIADEWIEAAQRSPVYALINTYRVALPLHPEYRT
MAV_1304|M.avium_104 LLDPNDTDVIAGARAQGIPDEWIEAAQRSPVYALIHTYRVALPLHPEYRT
Mvan_4545|M.vanbaalenii_PYR-1 LLDPSDPEVIAGARAEGISDEWIEAAQRSPIYALIHEYQVALPLHPEYRT
Mflv_2157|M.gilvum_PYR-GCK LLDPNDPAVISGARAEGISDEWIEAAQRSPIYALIHTFGVALPLHPEYRT
MSMEG_5139|M.smegmatis_MC2_155 LLDPTDPAVIAGARAEGISDEWIEAAQHSPVYKLIHTYGVALPLHPEFRT
TH_1884|M.thermoresistible__bu ILDPNDPQVIAAARAEGIPDDWIEAAQRSPVYALIHEYQVALPLHPEYRT
MMAR_5196|M.marinum_M -LYGHDP-----NDGVGGNGAFFLLLDEPEVYGLPPD-----PVVPTRDT
* *. . * . :: :.. :* * *: * *
Mb1194|M.bovis_AF2122/97 MPMVWYIPPLSPVVDAVSRDGHDGEDLGNLFGALDALRIPIAYLAELFTA
Rv1162|M.tuberculosis_H37Rv MPMVWYIPPLSPVVDAVSRDGHDGEDLGNLFGALDALRIPIAYLAELFTA
MAV_1304|M.avium_104 MPMVWYIPPLSPVVDAVSRDGHDGEDLGNLFGALDALRIPMQYLAELFTA
Mvan_4545|M.vanbaalenii_PYR-1 MPMVWYIPPLSPVVDAVSRDGHDGEDAGNLFGALEALRIPIEYLAGLFTA
Mflv_2157|M.gilvum_PYR-GCK VPMVWYIPPLSPVVDAVSRDGHDGEDLGNLFGALEALRIPIEYLAGLFTA
MSMEG_5139|M.smegmatis_MC2_155 VPMVWYIPPLSPVVDAVSRDGHDGEDLGNLFGALHALRIPLEYLAGLFTA
TH_1884|M.thermoresistible__bu MPMVWYIPPLSPVVDAVARDGHDGEDLGNLFGALSALRIPMQYLAGLFTA
MMAR_5196|M.marinum_M PAMWRYAGMAASALVAIAVSAFAGRGRP----------------------
.* * :..: *:: ... *..
Mb1194|M.bovis_AF2122/97 GDTEVVAGVLRRLAAMRCYMRDINLGRETQPHIPESVGMTEEQIYQMYRL
Rv1162|M.tuberculosis_H37Rv GDTEVVAGVLRRLAAMRCYMRDINLGRETQPHIPESVGMTEEQIYQMYRL
MAV_1304|M.avium_104 GDTAVVEGVLRRLAAMRSYMRDINLGRETQPHIPHSVGMTEEQIYEMYRL
Mvan_4545|M.vanbaalenii_PYR-1 GDTAVVEGVLRRLAAMRSYMRDVNLGRETQPHIPESVGMTEEQIYEMYRL
Mflv_2157|M.gilvum_PYR-GCK GDTAVVEGVLRRLAAMRSYMRDVNLGRETQPHIPESVGMTEEQIYQMYRL
MSMEG_5139|M.smegmatis_MC2_155 GDTRVVEGVLQRLAAMRSYMRDINLGRETQPHIPASVGMTEQQIYDMYRL
TH_1884|M.thermoresistible__bu GDTAVVEAALRRLAAMRSYMRDINLGRPTQPHIPESVGLTEEQVYNMYRL
MMAR_5196|M.marinum_M --------------------------------------------------
Mb1194|M.bovis_AF2122/97 LAVAKYEERYVIPTSYAGELPAAAMTDDMGCSLSVDGGPGMYESGPFGQG
Rv1162|M.tuberculosis_H37Rv LAVAKYEERYVIPTSYAGELPAAAMTDDMGCSLSVDGGPGMYESGPFGQG
MAV_1304|M.avium_104 LAIAKYEERYVIPTAFA---PQARDLEQMGCSLTGDGGPGMYESE-----
Mvan_4545|M.vanbaalenii_PYR-1 LALAKYDERYVIPTAYAA--VEPWSLEEPGCSLSFEGGPGMYESGPFGEA
Mflv_2157|M.gilvum_PYR-GCK LALAKYEERYVIPTAYAA--VEPLSMEESGCSLSFEGGPGMYDSGPFGEA
MSMEG_5139|M.smegmatis_MC2_155 LALAKYEERYVIPTAYG---TDGREVEEPTCALSFDGGPGMYESGPFGEA
TH_1884|M.thermoresistible__bu LALAKYDERYVIPTAYPA--TVPGAVEEAGCSLDFEGGPGMYESGPFGEA
MMAR_5196|M.marinum_M --------------------------------------------------
Mb1194|M.bovis_AF2122/97 SPTPVPIAVESFHALQHAG--SAATGGAGR-SRVNLLNWDPNGAAAGLFP
Rv1162|M.tuberculosis_H37Rv SPTPVPIAVESFHALQHAG--SAATGGAGR-SRVNLLNWDPNGAAAGLFP
MAV_1304|M.avium_104 -----PVAVETFHALKQRGGPTEAEPGSTR-PRVNLLNWDGGQVPAGMFP
Mvan_4545|M.vanbaalenii_PYR-1 SGQPIPVAVETFHALRQRQTSEHMAADEARPSRVNLLNWDGRGAPSGLFP
Mflv_2157|M.gilvum_PYR-GCK SGQPVPVAVETFHALKQRQTSEHMAANESRPSRVNLLNWDGRGAPSGLFP
MSMEG_5139|M.smegmatis_MC2_155 SGGPVPVAVETFHALQHRQTSDGMAANAEHPSRVNLLNWDGRGVPAGMFP
TH_1884|M.thermoresistible__bu SGDPVPVAVETFHALRHRQTSGGMAANASRPSRVNLLNWDGRGVPAGMFP
MMAR_5196|M.marinum_M --------------------------------------------------
Mb1194|M.bovis_AF2122/97 EPQPSKDVVQR
Rv1162|M.tuberculosis_H37Rv EPQPSKDVVQR
MAV_1304|M.avium_104 EAQRR------
Mvan_4545|M.vanbaalenii_PYR-1 QDGDR------
Mflv_2157|M.gilvum_PYR-GCK RNGDR------
MSMEG_5139|M.smegmatis_MC2_155 EDSQ-------
TH_1884|M.thermoresistible__bu DAEST------
MMAR_5196|M.marinum_M -----------