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VDSIRAVGTREIYRNNWLTVREDDIRRPDGTSGIYAVVDKPTYALVIPRDGDRFHLVEQFRYPIGMRRWE FPQGTAPGRADLDAGELAVRELREETGLVAAAMTEIGLLDVAPGMSSQRGRVFLATGITEGPHEREHEEQ DMRSAWFSRAEVEQMMRDRIITDAQTLAAWALMLLAGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4523 | - | - | 100% (178) | NUDIX hydrolase |
| M. vanbaalenii PYR-1 | Mvan_3282 | - | 6e-15 | 31.84% (179) | NUDIX hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1726 | - | 3e-17 | 36.20% (163) | hypothetical protein Mb1726 |
| M. gilvum PYR-GCK | Mflv_2174 | - | 1e-86 | 82.58% (178) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv1700 | - | 3e-17 | 36.20% (163) | hypothetical protein Rv1700 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2365 | - | 8e-15 | 31.95% (169) | MutT/nudix family protein |
| M. marinum M | MMAR_4125 | - | 7e-67 | 69.19% (172) | NUDIX hydrolase |
| M. avium 104 | MAV_1446 | - | 3e-67 | 70.86% (175) | nudix hydrolase |
| M. smegmatis MC2 155 | MSMEG_5118 | - | 2e-74 | 76.16% (172) | nudix hydrolase |
| M. thermoresistible (build 8) | TH_1834 | - | 2e-67 | 69.71% (175) | nudix hydrolase |
| M. ulcerans Agy99 | MUL_1689 | - | 3e-15 | 31.61% (174) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4523|M.vanbaalenii_PYR-1 ------------MDSIRAVGTREIYRNNWLTVREDDIRRPDGTSGIYAVV
Mflv_2174|M.gilvum_PYR-GCK MRLPLTLVILVGVEYIQAVGTREIYRNPWLTIREDEIRRPDGSPGVYAVV
MSMEG_5118|M.smegmatis_MC2_155 ------------MGMIRQVSTREVYRNNWLTLREDAIERPDGSDGIYAVV
TH_1834|M.thermoresistible__bu ------------VTDIRQVGSRQVYANRWMTLREDDIRLRDGRSGVYAVV
MMAR_4125|M.marinum_M ------------MRFIEPVASREIYRNRWMVLREDDIRRPDGSPGIYGVV
MAV_1446|M.avium_104 MSGVVFVAILGGVTFIERLASREIYRNPWMVLREDDIRRPDGSAGIYSVV
Mb1726|M.bovis_AF2122/97 --MAE--------HDFETISSETLHTGAIFALRRDQVRMPGGGIVTREVV
Rv1700|M.tuberculosis_H37Rv --MAE--------HDFETISSETLHTGAIFALRRDQVRMPGGGIVTREVV
MUL_1689|M.ulcerans_Agy99 --MAE--------HDFETISSETLYTGAIFALRRDRVRMPGDTTAVREVI
MAB_2365|M.abscessus_ATCC_1997 --MSDGTSGERERHEFVTLESEPVYMGGILALRRDRVAMPGGGSATREVV
: : :. :: . :.:*.* : .. *:
Mvan_4523|M.vanbaalenii_PYR-1 DKP-TYALVIPRDGDRFHLVEQFRYPIGMRRWEFPQGTAPGRADLDAGEL
Mflv_2174|M.gilvum_PYR-GCK DKP-TYALVIPRDGERFHLVEQFRYPIGLRRWEFPQGTAPDRAELDGADL
MSMEG_5118|M.smegmatis_MC2_155 DKP-TYALVIPHDGERFHLVEQYRYPLGLRRWEFPQGTAPDRQDLEPHAL
TH_1834|M.thermoresistible__bu DKP-DYALVIARDRDRFRLVEQYRYPIGLRRWEFPQGTAPDLADLEPEAL
MMAR_4125|M.marinum_M DKP-AYALVIAHDGNRFRLVEQFRYPVGARRWEFPQGTAPDLSDVEPAEL
MAV_1446|M.avium_104 DKP-SYALVMPYDGRRFGLVEQFRYPIGERRWEFPQGTAPELADADPVEL
Mb1726|M.bovis_AF2122/97 EHLGAVAIVAMDDNGNIPMVYQYRHTYGRRLWELPAG-LLDVAGEPPHLT
Rv1700|M.tuberculosis_H37Rv EHFGAVAIVAMDDNGNIPMVYQYRHTYGRRLWELPAG-LLDVAGEPPHLT
MUL_1689|M.ulcerans_Agy99 EHYGAVAIVAMDDNGNIPMVYQYRHAFGRRLLELPAG-LRDAAGEPSHVT
MAB_2365|M.abscessus_ATCC_1997 EHYGAVAVAAVDEAGRVALVYQYRHPLGHRLWELPAG-LLDIAGEDSQRA
:: *:. : .. :* *:*:. * * *:* *
Mvan_4523|M.vanbaalenii_PYR-1 AVRELREETGLVAAAMTEIGLLDVAPGMSSQRGRVFLATGITE-GPHERE
Mflv_2174|M.gilvum_PYR-GCK AARELREETGLTASSMTEIGLLDVAPGMSSQRGRVFLATGITE-GPHDRE
MSMEG_5118|M.smegmatis_MC2_155 AERELREETGLRAAHLVKLGLLDVAAGMSSQRGWVFLATELTE-GDHERE
TH_1834|M.thermoresistible__bu AARELREETGLRAGRLRRLGQLDVAPGMSSQRGWVFLATDLTE-GEHDRE
MMAR_4125|M.marinum_M AARELREETGLRAASFVSLGQLDTAPGLTSQRGWVFLATGITE-GESERE
MAV_1446|M.avium_104 ARRELREETGLRATTFESLGRLDVAPGMSSQRGWVFLATGIVE-GEADRE
Mb1726|M.bovis_AF2122/97 AARELREEVGLQASTWQVLVDLDTAPGFSDESVRVYLATGLREVGRPEAH
Rv1700|M.tuberculosis_H37Rv AARELREEVGLQASTWQVLVDLDTAPGFSDESVRVYLATGLREVGRPEAH
MUL_1689|M.ulcerans_Agy99 AARELHEEAGLQAEHWQVLIDLDSAPGFSDESVRVYLATGLSEVEQPEGH
MAB_2365|M.abscessus_ATCC_1997 AARELLEEAGIEAGTWRVLVDAAASPGFTDEVVRVFLATGLSHPGRGESH
* *** **.*: * : :.*::.: *:*** : . : .
Mvan_4523|M.vanbaalenii_PYR-1 HEEQDMRSAWFSRAEVEQMMRDRIITDAQTLAAWALMLLAGH--------
Mflv_2174|M.gilvum_PYR-GCK HEEQDMRSAWFTRSEVERMMRERVITDAQTIAAWTLMQLHDH--------
MSMEG_5118|M.smegmatis_MC2_155 HEEQDMHSAWFTRAEIEDMMRSGDITDAQSIAAWALLLLYERR-------
TH_1834|M.thermoresistible__bu PEEQDMHSAWFERSEVEAMIRSGQITDAQSIAAWTLFLLHERTAPLY---
MMAR_4125|M.marinum_M HEEQDMRSAWFARDEVEQMIRTGGIVDSQSIAAYGMFLLHRG--------
MAV_1446|M.avium_104 HEEQDMRSAWFSRDDVEQMIRTGVIADAQSIAAYGLFLLRPESTGAPVTD
Mb1726|M.bovis_AF2122/97 HEEADMTMGWYPIAEAARRVLRGEIVNSIAIAGVLAVHAVTTGFAQPRPL
Rv1700|M.tuberculosis_H37Rv HEEADMTMGWYPIAEAARRVLRGEIVNSIAIAGVLAVHAVTTGFAQPRPL
MUL_1689|M.ulcerans_Agy99 HEEADMTVRWFPLTEAVSKVFTGEIVNAIAVAGVLAAHSISTGLAQPRPL
MAB_2365|M.abscessus_ATCC_1997 DEEADMTVHWVPLSEAVSMVMAGEVVNAIAVAGILATH-IALGGHHTRPV
** ** * : : :.:: ::*.
Mvan_4523|M.vanbaalenii_PYR-1 ------------------
Mflv_2174|M.gilvum_PYR-GCK ------------------
MSMEG_5118|M.smegmatis_MC2_155 ------------------
TH_1834|M.thermoresistible__bu ------------------
MMAR_4125|M.marinum_M ------------------
MAV_1446|M.avium_104 QGQ---------------
Mb1726|M.bovis_AF2122/97 DTEWIDRPTAFATRRAER
Rv1700|M.tuberculosis_H37Rv DTEWIDRPTAFAARRAER
MUL_1689|M.ulcerans_Agy99 DSPWIDRPTAFMARKNSR
MAB_2365|M.abscessus_ATCC_1997 DAPWPDRPTAFAERKAAT