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AEGDPGRHEFTTVASETVYAGKIIALRADEVRMPGGGTARREVIEHFGAVAVVALDEDGRIVLIHQYRHA FGRRLWELPAGLLDFGGEPPHASAVRELAEEAGLAAEHWRTLIDVDSAPGFCDESVRVFLATGLRDVERP QAHDEEADMTVQRFDLADAVAKVYSGEIVNSSAVAGILAAHAMPDVSTLRPVDAPWVDRPTAFARRVGHP *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3282 | - | - | 100% (211) | NUDIX hydrolase |
| M. vanbaalenii PYR-1 | Mvan_4523 | - | 8e-15 | 31.84% (179) | NUDIX hydrolase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1726 | - | 1e-71 | 61.50% (200) | hypothetical protein Mb1726 |
| M. gilvum PYR-GCK | Mflv_3501 | - | 9e-95 | 76.67% (210) | NUDIX hydrolase |
| M. tuberculosis H37Rv | Rv1700 | - | 2e-72 | 62.00% (200) | hypothetical protein Rv1700 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2365 | - | 8e-68 | 61.27% (204) | MutT/nudix family protein |
| M. marinum M | MMAR_2505 | - | 5e-74 | 65.50% (200) | NUDIX hydrolase |
| M. avium 104 | MAV_3071 | - | 3e-74 | 67.00% (203) | MutT/nudix family protein |
| M. smegmatis MC2 155 | MSMEG_3745 | - | 1e-81 | 70.94% (203) | MutT/nudix family protein |
| M. thermoresistible (build 8) | TH_1543 | - | 1e-51 | 62.50% (160) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_1689 | - | 3e-74 | 65.50% (200) | NUDIX hydrolase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3282|M.vanbaalenii_PYR-1 MAEGDPGR---HEFTTVASETVYAGKIIALRADEVRMPGGGTARREVIEH
Mflv_3501|M.gilvum_PYR-GCK MAEDEPGL---HEFSTAASETVYVGKILALRGDEVRMPGGGTARREVVEH
MSMEG_3745|M.smegmatis_MC2_155 -----MGE---HDFETLASETVYVGNIFALRADEVSMPGGKSARREVVEH
Mb1726|M.bovis_AF2122/97 -----MAE---HDFETISSETLHTGAIFALRRDQVRMPGGGIVTREVVEH
Rv1700|M.tuberculosis_H37Rv -----MAE---HDFETISSETLHTGAIFALRRDQVRMPGGGIVTREVVEH
MMAR_2505|M.marinum_M -----MAE---HDFETISSETLYTGAIFALRRDRVRMPGDTTAVREVIEH
MUL_1689|M.ulcerans_Agy99 -----MAE---HDFETISSETLYTGAIFALRRDRVRMPGDTTAVREVIEH
MAV_3071|M.avium_104 -----MAE---HVFETASSETLYTGKIFALRRDQVRMPGGKVVTREIVEH
TH_1543|M.thermoresistible__bu --------------------------------------------------
MAB_2365|M.abscessus_ATCC_1997 MSDGTSGERERHEFVTLESEPVYMGGILALRRDRVAMPGGGSATREVVEH
Mvan_3282|M.vanbaalenii_PYR-1 FGAVAVVALDEDGRIVLIHQYRHAFGRRLWELPAGLLDFGGEPPHASAVR
Mflv_3501|M.gilvum_PYR-GCK FGAVAVVALDDEGRVVLVHQYRHAFGRRLWELPAGLLDSAGEDPHVTAAR
MSMEG_3745|M.smegmatis_MC2_155 YGAVAVVALDDDGNVVLVYQYRHPLGRRLWELPAGLLDLGGEPPEVTAAR
Mb1726|M.bovis_AF2122/97 LGAVAIVAMDDNGNIPMVYQYRHTYGRRLWELPAGLLDVAGEPPHLTAAR
Rv1700|M.tuberculosis_H37Rv FGAVAIVAMDDNGNIPMVYQYRHTYGRRLWELPAGLLDVAGEPPHLTAAR
MMAR_2505|M.marinum_M YGAVAIVAMDDNGNIPMVYQYRHAFGRRLLELPAGLRDAAGEPSHVTAAR
MUL_1689|M.ulcerans_Agy99 YGAVAIVAMDDNGNIPMVYQYRHAFGRRLLELPAGLRDAAGEPSHVTAAR
MAV_3071|M.avium_104 FGAVAVVAMDDDGNIPMVYQYRHAFGRRLWELPAGLLDVHGEAAHLTAAR
TH_1543|M.thermoresistible__bu --------MDADRNVALVHQYRHPVRRRLWELPAGLLDEPGEPPHLTAAR
MAB_2365|M.abscessus_ATCC_1997 YGAVAVAAVDEAGRVALVYQYRHPLGHRLWELPAGLLDIAGEDSQRAAAR
:* .: :::****. :** ****** * ** .. :*.*
Mvan_3282|M.vanbaalenii_PYR-1 ELAEEAGLAAEHWRTLIDVDSAPGFCDESVRVFLATGLRDVERPQAHDEE
Mflv_3501|M.gilvum_PYR-GCK ELVEEVGLAARDWWTLVDIDSAPGFCDESVRIFLATGLSDVDRPEAHDEE
MSMEG_3745|M.smegmatis_MC2_155 ELEEEVGLAASDWRVLVDLDSTPGFSDESVRVYLATGLTDVGRPEAEHEE
Mb1726|M.bovis_AF2122/97 ELREEVGLQASTWQVLVDLDTAPGFSDESVRVYLATGLREVGRPEAHHEE
Rv1700|M.tuberculosis_H37Rv ELREEVGLQASTWQVLVDLDTAPGFSDESVRVYLATGLREVGRPEAHHEE
MMAR_2505|M.marinum_M ELHEEAGLQAEHWQVLIDLDSAPGFSDESVRVYLATGLSEVEQPEGHHEE
MUL_1689|M.ulcerans_Agy99 ELHEEAGLQAEHWQVLIDLDSAPGFSDESVRVYLATGLSEVEQPEGHHEE
MAV_3071|M.avium_104 ELMEEAGLKAETWAVLVDLNSTPGFSDESVRVYLATGLTRVDRPEAHDEE
TH_1543|M.thermoresistible__bu ELEEEAGLAARDWRVLVDLVSSPGFSDECVRVYLATGLTEVPRPDAHHEE
MAB_2365|M.abscessus_ATCC_1997 ELLEEAGIEAGTWRVLVDAAASPGFTDEVVRVFLATGLSHPGRGESHDEE
** **.*: * * .*:* ::*** ** **::***** : :...**
Mvan_3282|M.vanbaalenii_PYR-1 ADMTVQRFDLADAVAKVYSGEIVNSSAVAGILAAHAMPDVSTLR-----P
Mflv_3501|M.gilvum_PYR-GCK ADLAVRRVDLAEAVARVFSGDIVNSIAVAGILAAHTMTGTDALR-----P
MSMEG_3745|M.smegmatis_MC2_155 ADMEVARVPLKEAVARVFSGDIVNGIAVAGILAAHSAKDIESLR-----R
Mb1726|M.bovis_AF2122/97 ADMTMGWYPIAEAARRVLRGEIVNSIAIAGVLAVHAVTTGFAQP----RP
Rv1700|M.tuberculosis_H37Rv ADMTMGWYPIAEAARRVLRGEIVNSIAIAGVLAVHAVTTGFAQP----RP
MMAR_2505|M.marinum_M ADMTVRWFPLTEAVSKVFTGEIVNAIAVAGVLAAHSISTGLAQP----RP
MUL_1689|M.ulcerans_Agy99 ADMTVRWFPLTEAVSKVFTGEIVNAIAVAGVLAAHSISTGLAQP----RP
MAV_3071|M.avium_104 ADMTLEWYPLADAARKVLSGEIVNAIAVAGILAAHAVTTGFERP----RP
TH_1543|M.thermoresistible__bu ADLTLRWFPLAEAVRMVLAGEIVNSIAVAGLLAAHAHAGAHPGPTAELRS
MAB_2365|M.abscessus_ATCC_1997 ADMTVHWVPLSEAVSMVMAGEVVNAIAVAGILATHIALGGHHTR-----P
**: : : :*. * *::**. *:**:**.*
Mvan_3282|M.vanbaalenii_PYR-1 VDAPWVDRPTAFARRVGHP
Mflv_3501|M.gilvum_PYR-GCK VDAPWVDRPQALGRRLGHS
MSMEG_3745|M.smegmatis_MC2_155 VDAPWVDRPTAFWRRKGLS
Mb1726|M.bovis_AF2122/97 LDTEWIDRPTAFATRRAER
Rv1700|M.tuberculosis_H37Rv LDTEWIDRPTAFAARRAER
MMAR_2505|M.marinum_M LDSPWIDRPTAFMARKNSG
MUL_1689|M.ulcerans_Agy99 LDSPWIDRPTAFMARKNSR
MAV_3071|M.avium_104 VDSPWQDRPTAFPARKAGR
TH_1543|M.thermoresistible__bu VDAPWPDRPTDFAARKAHR
MAB_2365|M.abscessus_ATCC_1997 VDAPWPDRPTAFAERKAAT
:*: * *** : *