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GIDTGTSNLVAVEPGAIREDTPAGSVIQYSDYEIDYSSPFAGGVAWIEGEYLPAEDAKISIFDTGFGHSD LTYTVAHVWHGNIFRLGDHLDRLLDGARKLRLDSGYTKDELADITKKCVSLSQLRESFVNLTITRGYGKR KGEKDLSKLTHQVYIYAIPYLWAFPPAEQIFGTTAVVPRHVRRAGRNTVDPTIKNYQWGDLTAASFEAKD RGARTAILMDADNCVAEGPGFNVCIVKDGKLASPSRNALPGITRKTVFEIAGAMGIEAALRDVTSHELYD ADEIMAVTTAGGVTPINTLDGVPIGDGEPGPVTVAIRDRFWALMDEPGPLIEAIQY*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4516 | - | - | 100% (337) | aminotransferase, class IV |
| M. vanbaalenii PYR-1 | Mvan_3573 | - | 2e-06 | 30.83% (133) | branched-chain amino acid aminotransferase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2233c | ilvE | 7e-06 | 29.32% (133) | branched-chain amino acid aminotransferase |
| M. gilvum PYR-GCK | Mflv_2940 | - | 1e-06 | 31.58% (133) | branched-chain amino acid aminotransferase |
| M. tuberculosis H37Rv | Rv2210c | ilvE | 7e-06 | 29.32% (133) | branched-chain amino acid aminotransferase |
| M. leprae Br4923 | MLBr_00866 | ilvE | 3e-05 | 28.57% (133) | branched-chain amino acid aminotransferase |
| M. abscessus ATCC 19977 | MAB_1950 | - | 2e-08 | 31.58% (133) | branched-chain amino acid aminotransferase (IlvE) |
| M. marinum M | MMAR_3255 | ilvE | 2e-06 | 32.33% (133) | branched-chain amino acid transaminase IlvE |
| M. avium 104 | MAV_2281 | ilvE | 5e-06 | 29.85% (134) | branched-chain amino acid aminotransferase |
| M. smegmatis MC2 155 | MSMEG_4276 | ilvE | 5e-06 | 30.08% (133) | branched-chain amino acid aminotransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3570 | ilvE | 1e-06 | 32.33% (133) | branched-chain amino acid aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3255|M.marinum_M MTRGSQQFTVTRATTPATEAERVSILADPGFGRYHTDHMVSIDFDE----
MUL_3570|M.ulcerans_Agy99 MTRGSQQFTVTRATTPATEAERVSILADPGFGRYHTDHMVSIDFDE----
Mb2233c|M.bovis_AF2122/97 MTSGSLQFTVLRAVNPATDAQRESMLRAPGFGKYHTDHMVSIDYAE----
Rv2210c|M.tuberculosis_H37Rv MTSGSLQFTVLRAVNPATDAQRESMLREPGFGKYHTDHMVSIDYAE----
MLBr_00866|M.leprae_Br4923 MTSGFLEFTVSLSAHPVTDAERESILAEPGFGKYHTDHMVSIDYID----
MAV_2281|M.avium_104 MTSGSLEFTVSRSTRPATDAERETILAEPGFGKYFTDHMVSIEYDETEA-
Mflv_2940|M.gilvum_PYR-GCK MTTG-LEFTVDRTANPASDEVRAGILANPGFGKFYTDHMVAIDYTA----
MSMEG_4276|M.smegmatis_MC2_155 MNSGPLEFTVSANTNPATDAVRESILANPGFGKYYTDHMVSIDYTV----
MAB_1950|M.abscessus_ATCC_1997 -MNPLPAFTRQLNPSPASPARRAEVLAAPGFGKYFTDHMVSIDWNA----
Mvan_4516|M.vanbaalenii_PYR-1 -------MGIDTGTSNLVAVEPGAIREDTPAGSVIQYSDYEIDYSSPFAG
: : . * *::
MMAR_3255|M.marinum_M GVGWHNPRVIGYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAW
MUL_3570|M.ulcerans_Agy99 GVGWHNPRVIGYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAW
Mb2233c|M.bovis_AF2122/97 GRGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAD
Rv2210c|M.tuberculosis_H37Rv GRGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAD
MLBr_00866|M.leprae_Br4923 GRGWHDARVIPYGPIQLDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPD
MAV_2281|M.avium_104 GRGWHDARVIPYGPIELDPSAIVLHYAQEIFEGLKAYRWADGSIVSFRAQ
Mflv_2940|M.gilvum_PYR-GCK DQGWHNARVSPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPE
MSMEG_4276|M.smegmatis_MC2_155 DEGWHNAQVIPYGPIQLDPSAIVLHYGQEIFEGLKAYRWADGSIVSFRPE
MAB_1950|M.abscessus_ATCC_1997 ENGWHNAQVVPYGPITLDPSAIVLHYAQEVFEGLKAYRQPDGTIAAFRPE
Mvan_4516|M.vanbaalenii_PYR-1 GVAWIEGEYLPAEDAKISIFDTGFGHSDLTYT--VAHVWHGN---IFRLG
.* : . :. : :.: : *: .. **
MMAR_3255|M.marinum_M ANAARLRSSARRMAIPELPEELFIESLTQLIAVDNVWVPPAGGEEALYLR
MUL_3570|M.ulcerans_Agy99 ANAARLRSSARRMAIPELPEELFIESLTQLIAVDNVWVPPAGGEEALYLR
Mb2233c|M.bovis_AF2122/97 ANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLR
Rv2210c|M.tuberculosis_H37Rv ANAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLR
MLBr_00866|M.leprae_Br4923 ANAARLRSSARRIAIPELPDELFIDSLCQLIAVDNAWVPRVGGEEALYLR
MAV_2281|M.avium_104 ANAARLRSSARRLAIPELPEELFLESLRQLIAVDNAWVPAAGGEEALYLR
Mflv_2940|M.gilvum_PYR-GCK SNAARLRASSRRLAIPELPDELFIESLRQLIAVDEKWVPPAGGEESLYLR
MSMEG_4276|M.smegmatis_MC2_155 ANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEESLYLR
MAB_1950|M.abscessus_ATCC_1997 ANGERLIQSCRRIAIPELPLELFIESLRQLIAVDAEWVPPGGGEESLYLR
Mvan_4516|M.vanbaalenii_PYR-1 DHLDRLLDGARKLRLDSG------YTKDELADITKKCVSLSQLRESFVNL
: ** ..*:: : . : :* : *. .*::
MMAR_3255|M.marinum_M PFIIATEPGLGVRPAKQYRYLLIASPAGAYFKGG----INPVSVWVSTDY
MUL_3570|M.ulcerans_Agy99 PFIIATEPGLGVRPAKQYRYLLIASPAGAYFKGG----INPVSVWVSTDY
Mb2233c|M.bovis_AF2122/97 PFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG----IAPVSVWVSTEY
Rv2210c|M.tuberculosis_H37Rv PFIFATEPGLGVRPATQYRYLLIASPAGAYFKGG----IAPVSVWVSTEY
MLBr_00866|M.leprae_Br4923 PFIFATEPGLGVRPAKQYRYLLIASPVGAYFKGG----INPVTVWVSMEY
MAV_2281|M.avium_104 PFVIATEPGLGVRPSKQYRYLLIASPAGAYFKGG----ISPVTVWVSTEY
Mflv_2940|M.gilvum_PYR-GCK PFVIATEPGLGVRPSDEYRYLVIASPAGAYFPRG----IKPVSVWLSHEY
MSMEG_4276|M.smegmatis_MC2_155 PFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGG----IKPVSVWLSHEY
MAB_1950|M.abscessus_ATCC_1997 PFIIATEAGLGVRPAGEYRYLLIASPAGAYFSQG----IKPVSVWLSHEY
Mvan_4516|M.vanbaalenii_PYR-1 TITRGYGKRKGEKDLSKLTHQVYIYAIPYLWAFPPAEQIFGTTAVVPRHV
.: . * : : : : . : * .:. :. .
MMAR_3255|M.marinum_M VRACPGGTGAAKFGGNYAASLLAQAEATENGCDQVVWLDSVERRYVEEMG
MUL_3570|M.ulcerans_Agy99 VRACPGGTGAAKFGGNYAASLLAQAEATENGCDQVVWLDSVERRYVEEMG
Mb2233c|M.bovis_AF2122/97 VRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMG
Rv2210c|M.tuberculosis_H37Rv VRACPGGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMG
MLBr_00866|M.leprae_Br4923 VRASPGGTGAAKFGGNYAASLLAQTEAAANGCDQVVWLDAVERRFVEEMG
MAV_2281|M.avium_104 VRASPGGTGAAKFGGNYAASLSAQAEAAANGCDQVVWLDAVERRFVEEMG
Mflv_2940|M.gilvum_PYR-GCK VRASPGGTGAAKFGGNYAASLLAQAEAASHGCDQVVWLDAIERRYVEEMG
MSMEG_4276|M.smegmatis_MC2_155 VRASPGGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMG
MAB_1950|M.abscessus_ATCC_1997 VRAAPGGIGAAKTGGNYAASLVAQAQAAEEGCDQVVWLDAIERRYIEEMG
Mvan_4516|M.vanbaalenii_PYR-1 RRAGRNTVDPTIKNYQWGDLTAASFEAKDRGARTAILMDADN--CVAEGP
** . ..: . ::. *. :* *. .: :*: : : *
MMAR_3255|M.marinum_M GMNIFFVLGKGGSARLVTPELSGSLLPGITRDSLLQLALDAGFAVEERKI
MUL_3570|M.ulcerans_Agy99 GMNIFFVLGKGGSARLVTPELSGSLLPGITRDSLLQLALDAGFAVEERKI
Mb2233c|M.bovis_AF2122/97 GMNIFFVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRI
Rv2210c|M.tuberculosis_H37Rv GMNIFFVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRI
MLBr_00866|M.leprae_Br4923 GMNIFFVLGSGGSARLVTPELSGSLLPGVTRASLLQLAIDAGFSVEERKI
MAV_2281|M.avium_104 GMNIFFVFGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERKI
Mflv_2940|M.gilvum_PYR-GCK GMNLFFVFGSGGTARLVTPELSGSLLPGITRNSLLQLATDAGFTVEERKI
MSMEG_4276|M.smegmatis_MC2_155 GMNLFFVFGSGGSARLVTPELSGSLLPGITRDSLLQLATDAGFAVEERKI
MAB_1950|M.abscessus_ATCC_1997 GMNLFFVFGRDGEARLVTPELSGALLPGVTRKSLLQLASDAGFAIEERKI
Mvan_4516|M.vanbaalenii_PYR-1 GFNVCIVK----DGKLASPSRN--ALPGITRKTVFEIAGAMGIEAALRDV
*:*: :* .:*.:*. . ***:** :::::* *: * :
MMAR_3255|M.marinum_M DIAEWQKKATAGEITEVFACGTAAVITPVSRVKYGDGEFTIADGQPGEVT
MUL_3570|M.ulcerans_Agy99 DIAEWQKKAAAGEITEVFACGTAAVITPVSRVKYGDGEFTIADGQPGEVT
Mb2233c|M.bovis_AF2122/97 DIDEWQKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVT
Rv2210c|M.tuberculosis_H37Rv DIDEWQKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVT
MLBr_00866|M.leprae_Br4923 DIDEWQKKAAAGEITEVFACGTAAFITPVSRVKYGDTEFTIAGGAPGEVT
MAV_2281|M.avium_104 DIDEWQKKAAAGEITEVFACGTAAVITPVSQVKYGETEFTIADGQPGEVT
Mflv_2940|M.gilvum_PYR-GCK DVDEWQKKAAAGEITEVFACGTAAVITPVSHVKHGDGEFTIADGEPGEIT
MSMEG_4276|M.smegmatis_MC2_155 DVDEWQKKAGAGEITEVFACGTAAVITPVSHVKHHDGEFTIADGQPGEIT
MAB_1950|M.abscessus_ATCC_1997 DVDELEKKTASGEITEVFACGTAAVITPVGRVKHSGGEFTIGDGEPGEVT
Mvan_4516|M.vanbaalenii_PYR-1 TSHELY------DADEIMAVTTAGGVTPINTLDG----VPIGDGEPGPVT
* : *::* **. :**: : . *..* ** :*
MMAR_3255|M.marinum_M MALRDTLTGIQR--GTFADTHGWMSRLS
MUL_3570|M.ulcerans_Agy99 MALRDTLTGIQR--GTFADTHGWMSRLS
Mb2233c|M.bovis_AF2122/97 MALRDTLTGIQR--GTFADTHGWMARLG
Rv2210c|M.tuberculosis_H37Rv MALRDTLTGIQR--GTFADTHGWMARLG
MLBr_00866|M.leprae_Br4923 MALRDTLTGIQR--GTFADTHGWMARLG
MAV_2281|M.avium_104 MALRDTLTGIQR--GTFADTHGWMTRLG
Mflv_2940|M.gilvum_PYR-GCK MALRDTLTGIQR--GTFADTHGWMTKLS
MSMEG_4276|M.smegmatis_MC2_155 MALRDTLTGIQR--GTFADTHGWMARLN
MAB_1950|M.abscessus_ATCC_1997 MALRDTLTGIQR--GTFADTHGWITQLG
Mvan_4516|M.vanbaalenii_PYR-1 VAIRDRFWALMDEPGPLIEAIQY-----
:*:** : .: *.: :: :