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TEGLEFTVDRNANPASDEVRAQILANPGFGRFHTDHMVSIDYTDGKGWHDARVMPYGPIELDPSAIVLHY AQEVFEGLKAYRWADGSIVSFRPEANAARLRTSARRLAIPELPDELFIRSLRELIAVDEKWVPAAGGEES LYLRPFIIATEPGLGVRPASEYRYLVIGSPAGAYFPRGIKPVSVWLSHEYVRASPGGTGAAKFGGNYAAS LLAQAEASAHGCDQVVWLDAIERRYIEEMGGMNLFFVFGSGGTARLVTPELSGSLLPGITRNSLLQLATD AGFAVEERKIDVDEWQKKAAAGEITEVFACGTAAVITPVSHVKHGDGEFTIADGEPGEITMALRDTLTGI QRGTFADTHGWMARLS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3573 | - | - | 100% (367) | branched-chain amino acid aminotransferase |
| M. vanbaalenii PYR-1 | Mvan_4516 | - | 2e-06 | 30.83% (133) | aminotransferase, class IV |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2233c | ilvE | 1e-180 | 83.11% (367) | branched-chain amino acid aminotransferase |
| M. gilvum PYR-GCK | Mflv_2940 | - | 0.0 | 92.64% (367) | branched-chain amino acid aminotransferase |
| M. tuberculosis H37Rv | Rv2210c | ilvE | 1e-180 | 83.11% (367) | branched-chain amino acid aminotransferase |
| M. leprae Br4923 | MLBr_00866 | ilvE | 0.0 | 82.83% (367) | branched-chain amino acid aminotransferase |
| M. abscessus ATCC 19977 | MAB_1950 | - | 1e-166 | 78.89% (360) | branched-chain amino acid aminotransferase (IlvE) |
| M. marinum M | MMAR_3255 | ilvE | 1e-177 | 81.79% (368) | branched-chain amino acid transaminase IlvE |
| M. avium 104 | MAV_2281 | ilvE | 0.0 | 82.70% (370) | branched-chain amino acid aminotransferase |
| M. smegmatis MC2 155 | MSMEG_4276 | ilvE | 0.0 | 87.88% (363) | branched-chain amino acid aminotransferase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_3570 | ilvE | 1e-178 | 82.07% (368) | branched-chain amino acid aminotransferase |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_3573|M.vanbaalenii_PYR-1 MTEG-LEFTVDRNANPASDEVRAQILANPGFGRFHTDHMVSIDYTD---G
Mflv_2940|M.gilvum_PYR-GCK MTTG-LEFTVDRTANPASDEVRAGILANPGFGKFYTDHMVAIDYTA---D
MMAR_3255|M.marinum_M MTRGSQQFTVTRATTPATEAERVSILADPGFGRYHTDHMVSIDFDE---G
MUL_3570|M.ulcerans_Agy99 MTRGSQQFTVTRATTPATEAERVSILADPGFGRYHTDHMVSIDFDE---G
Mb2233c|M.bovis_AF2122/97 MTSGSLQFTVLRAVNPATDAQRESMLRAPGFGKYHTDHMVSIDYAE---G
Rv2210c|M.tuberculosis_H37Rv MTSGSLQFTVLRAVNPATDAQRESMLREPGFGKYHTDHMVSIDYAE---G
MLBr_00866|M.leprae_Br4923 MTSGFLEFTVSLSAHPVTDAERESILAEPGFGKYHTDHMVSIDYID---G
MAV_2281|M.avium_104 MTSGSLEFTVSRSTRPATDAERETILAEPGFGKYFTDHMVSIEYDETEAG
MSMEG_4276|M.smegmatis_MC2_155 MNSGPLEFTVSANTNPATDAVRESILANPGFGKYYTDHMVSIDYTV---D
MAB_1950|M.abscessus_ATCC_1997 -MNPLPAFTRQLNPSPASPARRAEVLAAPGFGKYFTDHMVSIDWNA---E
** *.: * :* ****::.*****:*::
Mvan_3573|M.vanbaalenii_PYR-1 KGWHDARVMPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPEA
Mflv_2940|M.gilvum_PYR-GCK QGWHNARVSPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPES
MMAR_3255|M.marinum_M VGWHNPRVIGYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAWA
MUL_3570|M.ulcerans_Agy99 VGWHNPRVIGYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAWA
Mb2233c|M.bovis_AF2122/97 RGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRADA
Rv2210c|M.tuberculosis_H37Rv RGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRADA
MLBr_00866|M.leprae_Br4923 RGWHDARVIPYGPIQLDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPDA
MAV_2281|M.avium_104 RGWHDARVIPYGPIELDPSAIVLHYAQEIFEGLKAYRWADGSIVSFRAQA
MSMEG_4276|M.smegmatis_MC2_155 EGWHNAQVIPYGPIQLDPSAIVLHYGQEIFEGLKAYRWADGSIVSFRPEA
MAB_1950|M.abscessus_ATCC_1997 NGWHNAQVVPYGPITLDPSAIVLHYAQEVFEGLKAYRQPDGTIAAFRPEA
***:.:* **** **********.**:******** .**:*.:**. :
Mvan_3573|M.vanbaalenii_PYR-1 NAARLRTSARRLAIPELPDELFIRSLRELIAVDEKWVPAAGGEESLYLRP
Mflv_2940|M.gilvum_PYR-GCK NAARLRASSRRLAIPELPDELFIESLRQLIAVDEKWVPPAGGEESLYLRP
MMAR_3255|M.marinum_M NAARLRSSARRMAIPELPEELFIESLTQLIAVDNVWVPPAGGEEALYLRP
MUL_3570|M.ulcerans_Agy99 NAARLRSSARRMAIPELPEELFIESLTQLIAVDNVWVPPAGGEEALYLRP
Mb2233c|M.bovis_AF2122/97 NAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLRP
Rv2210c|M.tuberculosis_H37Rv NAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLRP
MLBr_00866|M.leprae_Br4923 NAARLRSSARRIAIPELPDELFIDSLCQLIAVDNAWVPRVGGEEALYLRP
MAV_2281|M.avium_104 NAARLRSSARRLAIPELPEELFLESLRQLIAVDNAWVPAAGGEEALYLRP
MSMEG_4276|M.smegmatis_MC2_155 NAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEESLYLRP
MAB_1950|M.abscessus_ATCC_1997 NGERLIQSCRRIAIPELPLELFIESLRQLIAVDAEWVPPGGGEESLYLRP
*. ** *.**:****** :*: ** :***** *** ****:*****
Mvan_3573|M.vanbaalenii_PYR-1 FIIATEPGLGVRPASEYRYLVIGSPAGAYFPRGIKPVSVWLSHEYVRASP
Mflv_2940|M.gilvum_PYR-GCK FVIATEPGLGVRPSDEYRYLVIASPAGAYFPRGIKPVSVWLSHEYVRASP
MMAR_3255|M.marinum_M FIIATEPGLGVRPAKQYRYLLIASPAGAYFKGGINPVSVWVSTDYVRACP
MUL_3570|M.ulcerans_Agy99 FIIATEPGLGVRPAKQYRYLLIASPAGAYFKGGINPVSVWVSTDYVRACP
Mb2233c|M.bovis_AF2122/97 FIFATEPGLGVRPATQYRYLLIASPAGAYFKGGIAPVSVWVSTEYVRACP
Rv2210c|M.tuberculosis_H37Rv FIFATEPGLGVRPATQYRYLLIASPAGAYFKGGIAPVSVWVSTEYVRACP
MLBr_00866|M.leprae_Br4923 FIFATEPGLGVRPAKQYRYLLIASPVGAYFKGGINPVTVWVSMEYVRASP
MAV_2281|M.avium_104 FVIATEPGLGVRPSKQYRYLLIASPAGAYFKGGISPVTVWVSTEYVRASP
MSMEG_4276|M.smegmatis_MC2_155 FVIATEPGLGVRPSNEYRYLLIASPAGAYFKGGIKPVSVWLSHEYVRASP
MAB_1950|M.abscessus_ATCC_1997 FIIATEAGLGVRPAGEYRYLLIASPAGAYFSQGIKPVSVWLSHEYVRAAP
*::***.******: :****:*.**.**** ** **:**:* :****.*
Mvan_3573|M.vanbaalenii_PYR-1 GGTGAAKFGGNYAASLLAQAEASAHGCDQVVWLDAIERRYIEEMGGMNLF
Mflv_2940|M.gilvum_PYR-GCK GGTGAAKFGGNYAASLLAQAEAASHGCDQVVWLDAIERRYVEEMGGMNLF
MMAR_3255|M.marinum_M GGTGAAKFGGNYAASLLAQAEATENGCDQVVWLDSVERRYVEEMGGMNIF
MUL_3570|M.ulcerans_Agy99 GGTGAAKFGGNYAASLLAQAEATENGCDQVVWLDSVERRYVEEMGGMNIF
Mb2233c|M.bovis_AF2122/97 GGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF
Rv2210c|M.tuberculosis_H37Rv GGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF
MLBr_00866|M.leprae_Br4923 GGTGAAKFGGNYAASLLAQTEAAANGCDQVVWLDAVERRFVEEMGGMNIF
MAV_2281|M.avium_104 GGTGAAKFGGNYAASLSAQAEAAANGCDQVVWLDAVERRFVEEMGGMNIF
MSMEG_4276|M.smegmatis_MC2_155 GGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLF
MAB_1950|M.abscessus_ATCC_1997 GGIGAAKTGGNYAASLVAQAQAAEEGCDQVVWLDAIERRYIEEMGGMNLF
** **** ******** **::*: *********::***::*******:*
Mvan_3573|M.vanbaalenii_PYR-1 FVFGSGGTARLVTPELSGSLLPGITRNSLLQLATDAGFAVEERKIDVDEW
Mflv_2940|M.gilvum_PYR-GCK FVFGSGGTARLVTPELSGSLLPGITRNSLLQLATDAGFTVEERKIDVDEW
MMAR_3255|M.marinum_M FVLGKGGSARLVTPELSGSLLPGITRDSLLQLALDAGFAVEERKIDIAEW
MUL_3570|M.ulcerans_Agy99 FVLGKGGSARLVTPELSGSLLPGITRDSLLQLALDAGFAVEERKIDIAEW
Mb2233c|M.bovis_AF2122/97 FVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRIDIDEW
Rv2210c|M.tuberculosis_H37Rv FVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRIDIDEW
MLBr_00866|M.leprae_Br4923 FVLGSGGSARLVTPELSGSLLPGVTRASLLQLAIDAGFSVEERKIDIDEW
MAV_2281|M.avium_104 FVFGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERKIDIDEW
MSMEG_4276|M.smegmatis_MC2_155 FVFGSGGSARLVTPELSGSLLPGITRDSLLQLATDAGFAVEERKIDVDEW
MAB_1950|M.abscessus_ATCC_1997 FVFGRDGEARLVTPELSGALLPGVTRKSLLQLASDAGFAIEERKIDVDEL
**:* .* **********:****:** ****** ****::***:**: *
Mvan_3573|M.vanbaalenii_PYR-1 QKKAAAGEITEVFACGTAAVITPVSHVKHGDGEFTIADGEPGEITMALRD
Mflv_2940|M.gilvum_PYR-GCK QKKAAAGEITEVFACGTAAVITPVSHVKHGDGEFTIADGEPGEITMALRD
MMAR_3255|M.marinum_M QKKATAGEITEVFACGTAAVITPVSRVKYGDGEFTIADGQPGEVTMALRD
MUL_3570|M.ulcerans_Agy99 QKKAAAGEITEVFACGTAAVITPVSRVKYGDGEFTIADGQPGEVTMALRD
Mb2233c|M.bovis_AF2122/97 QKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVTMALRD
Rv2210c|M.tuberculosis_H37Rv QKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVTMALRD
MLBr_00866|M.leprae_Br4923 QKKAAAGEITEVFACGTAAFITPVSRVKYGDTEFTIAGGAPGEVTMALRD
MAV_2281|M.avium_104 QKKAAAGEITEVFACGTAAVITPVSQVKYGETEFTIADGQPGEVTMALRD
MSMEG_4276|M.smegmatis_MC2_155 QKKAGAGEITEVFACGTAAVITPVSHVKHHDGEFTIADGQPGEITMALRD
MAB_1950|M.abscessus_ATCC_1997 EKKTASGEITEVFACGTAAVITPVGRVKHSGGEFTIGDGEPGEVTMALRD
:**: :*************.****.:*:: ** *..* ***:******
Mvan_3573|M.vanbaalenii_PYR-1 TLTGIQRGTFADTHGWMARLS
Mflv_2940|M.gilvum_PYR-GCK TLTGIQRGTFADTHGWMTKLS
MMAR_3255|M.marinum_M TLTGIQRGTFADTHGWMSRLS
MUL_3570|M.ulcerans_Agy99 TLTGIQRGTFADTHGWMSRLS
Mb2233c|M.bovis_AF2122/97 TLTGIQRGTFADTHGWMARLG
Rv2210c|M.tuberculosis_H37Rv TLTGIQRGTFADTHGWMARLG
MLBr_00866|M.leprae_Br4923 TLTGIQRGTFADTHGWMARLG
MAV_2281|M.avium_104 TLTGIQRGTFADTHGWMTRLG
MSMEG_4276|M.smegmatis_MC2_155 TLTGIQRGTFADTHGWMARLN
MAB_1950|M.abscessus_ATCC_1997 TLTGIQRGTFADTHGWITQLG
****************:::*.