For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. smegmatis MC2 155 MSMEG_4276 (ilvE)

annotation: branched-chain amino acid aminotransferase
coordinates: 4359885 - 4360991
length: 368

NSGPLEFTVSANTNPATDAVRESILANPGFGKYYTDHMVSIDYTVDEGWHNAQVIPYGPIQLDPSAIVLH
YGQEIFEGLKAYRWADGSIVSFRPEANAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEE
SLYLRPFVIATEPGLGVRPSNEYRYLLIASPAGAYFKGGIKPVSVWLSHEYVRASPGGTGAAKFGGNYAA
SLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLFFVFGSGGSARLVTPELSGSLLPGITRDSLLQLAT
DAGFAVEERKIDVDEWQKKAGAGEITEVFACGTAAVITPVSHVKHHDGEFTIADGQPGEITMALRDTLTG
IQRGTFADTHGWMARLN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. smegmatis MC2 155MSMEG_4276ilvE-100% (368)branched-chain amino acid aminotransferase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb2233cilvE0.084.74% (367) branched-chain amino acid aminotransferase
M. gilvum PYR-GCKMflv_2940-0.089.26% (363) branched-chain amino acid aminotransferase
M. tuberculosis H37RvRv2210cilvE0.084.74% (367) branched-chain amino acid aminotransferase
M. leprae Br4923MLBr_00866ilvE0.083.11% (367) branched-chain amino acid aminotransferase
M. abscessus ATCC 19977MAB_1950-1e-17079.72% (360) branched-chain amino acid aminotransferase (IlvE)
M. marinum MMMAR_3255ilvE1e-18083.15% (368) branched-chain amino acid transaminase IlvE
M. avium 104MAV_2281ilvE0.085.95% (370) branched-chain amino acid aminotransferase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_3570ilvE1e-18083.15% (368) branched-chain amino acid aminotransferase
M. vanbaalenii PYR-1Mvan_3573-0.087.88% (363) branched-chain amino acid aminotransferase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_2940|M.gilvum_PYR-GCK          MTTG-LEFTVDRTANPASDEVRAGILANPGFGKFYTDHMVAIDYTA---D
Mvan_3573|M.vanbaalenii_PYR-1       MTEG-LEFTVDRNANPASDEVRAQILANPGFGRFHTDHMVSIDYTD---G
MMAR_3255|M.marinum_M               MTRGSQQFTVTRATTPATEAERVSILADPGFGRYHTDHMVSIDFDE---G
MUL_3570|M.ulcerans_Agy99           MTRGSQQFTVTRATTPATEAERVSILADPGFGRYHTDHMVSIDFDE---G
Mb2233c|M.bovis_AF2122/97           MTSGSLQFTVLRAVNPATDAQRESMLRAPGFGKYHTDHMVSIDYAE---G
Rv2210c|M.tuberculosis_H37Rv        MTSGSLQFTVLRAVNPATDAQRESMLREPGFGKYHTDHMVSIDYAE---G
MLBr_00866|M.leprae_Br4923          MTSGFLEFTVSLSAHPVTDAERESILAEPGFGKYHTDHMVSIDYID---G
MAV_2281|M.avium_104                MTSGSLEFTVSRSTRPATDAERETILAEPGFGKYFTDHMVSIEYDETEAG
MSMEG_4276|M.smegmatis_MC2_155      MNSGPLEFTVSANTNPATDAVRESILANPGFGKYYTDHMVSIDYTV---D
MAB_1950|M.abscessus_ATCC_1997      -MNPLPAFTRQLNPSPASPARRAEVLAAPGFGKYFTDHMVSIDWNA---E
                                           **      *.:   *  :*  ****::.*****:*::      

Mflv_2940|M.gilvum_PYR-GCK          QGWHNARVSPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPES
Mvan_3573|M.vanbaalenii_PYR-1       KGWHDARVMPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPEA
MMAR_3255|M.marinum_M               VGWHNPRVIGYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAWA
MUL_3570|M.ulcerans_Agy99           VGWHNPRVIGYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRAWA
Mb2233c|M.bovis_AF2122/97           RGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRADA
Rv2210c|M.tuberculosis_H37Rv        RGWHNARVIPYGPIELDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRADA
MLBr_00866|M.leprae_Br4923          RGWHDARVIPYGPIQLDPSAIVLHYAQEVFEGLKAYRWADGSIVSFRPDA
MAV_2281|M.avium_104                RGWHDARVIPYGPIELDPSAIVLHYAQEIFEGLKAYRWADGSIVSFRAQA
MSMEG_4276|M.smegmatis_MC2_155      EGWHNAQVIPYGPIQLDPSAIVLHYGQEIFEGLKAYRWADGSIVSFRPEA
MAB_1950|M.abscessus_ATCC_1997      NGWHNAQVVPYGPITLDPSAIVLHYAQEVFEGLKAYRQPDGTIAAFRPEA
                                     ***:.:*  **** **********.**:******** .**:*.:**. :

Mflv_2940|M.gilvum_PYR-GCK          NAARLRASSRRLAIPELPDELFIESLRQLIAVDEKWVPPAGGEESLYLRP
Mvan_3573|M.vanbaalenii_PYR-1       NAARLRTSARRLAIPELPDELFIRSLRELIAVDEKWVPAAGGEESLYLRP
MMAR_3255|M.marinum_M               NAARLRSSARRMAIPELPEELFIESLTQLIAVDNVWVPPAGGEEALYLRP
MUL_3570|M.ulcerans_Agy99           NAARLRSSARRMAIPELPEELFIESLTQLIAVDNVWVPPAGGEEALYLRP
Mb2233c|M.bovis_AF2122/97           NAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLRP
Rv2210c|M.tuberculosis_H37Rv        NAARLRSSARRLAIPELPDAVFIESLRQLIAVDKAWVPGAGGEEALYLRP
MLBr_00866|M.leprae_Br4923          NAARLRSSARRIAIPELPDELFIDSLCQLIAVDNAWVPRVGGEEALYLRP
MAV_2281|M.avium_104                NAARLRSSARRLAIPELPEELFLESLRQLIAVDNAWVPAAGGEEALYLRP
MSMEG_4276|M.smegmatis_MC2_155      NAARLQSSARRLAIPELPEEVFIESLRQLIAVDEKWVPPAGGEESLYLRP
MAB_1950|M.abscessus_ATCC_1997      NGERLIQSCRRIAIPELPLELFIESLRQLIAVDAEWVPPGGGEESLYLRP
                                    *. **  *.**:******  :*: ** :*****  ***  ****:*****

Mflv_2940|M.gilvum_PYR-GCK          FVIATEPGLGVRPSDEYRYLVIASPAGAYFPRGIKPVSVWLSHEYVRASP
Mvan_3573|M.vanbaalenii_PYR-1       FIIATEPGLGVRPASEYRYLVIGSPAGAYFPRGIKPVSVWLSHEYVRASP
MMAR_3255|M.marinum_M               FIIATEPGLGVRPAKQYRYLLIASPAGAYFKGGINPVSVWVSTDYVRACP
MUL_3570|M.ulcerans_Agy99           FIIATEPGLGVRPAKQYRYLLIASPAGAYFKGGINPVSVWVSTDYVRACP
Mb2233c|M.bovis_AF2122/97           FIFATEPGLGVRPATQYRYLLIASPAGAYFKGGIAPVSVWVSTEYVRACP
Rv2210c|M.tuberculosis_H37Rv        FIFATEPGLGVRPATQYRYLLIASPAGAYFKGGIAPVSVWVSTEYVRACP
MLBr_00866|M.leprae_Br4923          FIFATEPGLGVRPAKQYRYLLIASPVGAYFKGGINPVTVWVSMEYVRASP
MAV_2281|M.avium_104                FVIATEPGLGVRPSKQYRYLLIASPAGAYFKGGISPVTVWVSTEYVRASP
MSMEG_4276|M.smegmatis_MC2_155      FVIATEPGLGVRPSNEYRYLLIASPAGAYFKGGIKPVSVWLSHEYVRASP
MAB_1950|M.abscessus_ATCC_1997      FIIATEAGLGVRPAGEYRYLLIASPAGAYFSQGIKPVSVWLSHEYVRAAP
                                    *::***.******: :****:*.**.****  ** **:**:* :****.*

Mflv_2940|M.gilvum_PYR-GCK          GGTGAAKFGGNYAASLLAQAEAASHGCDQVVWLDAIERRYVEEMGGMNLF
Mvan_3573|M.vanbaalenii_PYR-1       GGTGAAKFGGNYAASLLAQAEASAHGCDQVVWLDAIERRYIEEMGGMNLF
MMAR_3255|M.marinum_M               GGTGAAKFGGNYAASLLAQAEATENGCDQVVWLDSVERRYVEEMGGMNIF
MUL_3570|M.ulcerans_Agy99           GGTGAAKFGGNYAASLLAQAEATENGCDQVVWLDSVERRYVEEMGGMNIF
Mb2233c|M.bovis_AF2122/97           GGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF
Rv2210c|M.tuberculosis_H37Rv        GGTGAAKFGGNYAASLLAQAEAAENGCDQVVWLDAVERRYIEEMGGMNIF
MLBr_00866|M.leprae_Br4923          GGTGAAKFGGNYAASLLAQTEAAANGCDQVVWLDAVERRFVEEMGGMNIF
MAV_2281|M.avium_104                GGTGAAKFGGNYAASLSAQAEAAANGCDQVVWLDAVERRFVEEMGGMNIF
MSMEG_4276|M.smegmatis_MC2_155      GGTGAAKFGGNYAASLLAQAQAAEMGCDQVVWLDAIERRYVEEMGGMNLF
MAB_1950|M.abscessus_ATCC_1997      GGIGAAKTGGNYAASLVAQAQAAEEGCDQVVWLDAIERRYIEEMGGMNLF
                                    ** **** ******** **::*:  *********::***::*******:*

Mflv_2940|M.gilvum_PYR-GCK          FVFGSGGTARLVTPELSGSLLPGITRNSLLQLATDAGFTVEERKIDVDEW
Mvan_3573|M.vanbaalenii_PYR-1       FVFGSGGTARLVTPELSGSLLPGITRNSLLQLATDAGFAVEERKIDVDEW
MMAR_3255|M.marinum_M               FVLGKGGSARLVTPELSGSLLPGITRDSLLQLALDAGFAVEERKIDIAEW
MUL_3570|M.ulcerans_Agy99           FVLGKGGSARLVTPELSGSLLPGITRDSLLQLALDAGFAVEERKIDIAEW
Mb2233c|M.bovis_AF2122/97           FVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRIDIDEW
Rv2210c|M.tuberculosis_H37Rv        FVLGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERRIDIDEW
MLBr_00866|M.leprae_Br4923          FVLGSGGSARLVTPELSGSLLPGVTRASLLQLAIDAGFSVEERKIDIDEW
MAV_2281|M.avium_104                FVFGSGGSARLVTPELSGSLLPGITRDSLLQLAIDAGFAVEERKIDIDEW
MSMEG_4276|M.smegmatis_MC2_155      FVFGSGGSARLVTPELSGSLLPGITRDSLLQLATDAGFAVEERKIDVDEW
MAB_1950|M.abscessus_ATCC_1997      FVFGRDGEARLVTPELSGALLPGVTRKSLLQLASDAGFAIEERKIDVDEL
                                    **:* .* **********:****:** ****** ****::***:**: * 

Mflv_2940|M.gilvum_PYR-GCK          QKKAAAGEITEVFACGTAAVITPVSHVKHGDGEFTIADGEPGEITMALRD
Mvan_3573|M.vanbaalenii_PYR-1       QKKAAAGEITEVFACGTAAVITPVSHVKHGDGEFTIADGEPGEITMALRD
MMAR_3255|M.marinum_M               QKKATAGEITEVFACGTAAVITPVSRVKYGDGEFTIADGQPGEVTMALRD
MUL_3570|M.ulcerans_Agy99           QKKAAAGEITEVFACGTAAVITPVSRVKYGDGEFTIADGQPGEVTMALRD
Mb2233c|M.bovis_AF2122/97           QKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVTMALRD
Rv2210c|M.tuberculosis_H37Rv        QKKAAAGEITEVFACGTAAVITPVARVRHGASEFRIADGQPGEVTMALRD
MLBr_00866|M.leprae_Br4923          QKKAAAGEITEVFACGTAAFITPVSRVKYGDTEFTIAGGAPGEVTMALRD
MAV_2281|M.avium_104                QKKAAAGEITEVFACGTAAVITPVSQVKYGETEFTIADGQPGEVTMALRD
MSMEG_4276|M.smegmatis_MC2_155      QKKAGAGEITEVFACGTAAVITPVSHVKHHDGEFTIADGQPGEITMALRD
MAB_1950|M.abscessus_ATCC_1997      EKKTASGEITEVFACGTAAVITPVGRVKHSGGEFTIGDGEPGEVTMALRD
                                    :**: :*************.****.:*::   ** *..* ***:******

Mflv_2940|M.gilvum_PYR-GCK          TLTGIQRGTFADTHGWMTKLS
Mvan_3573|M.vanbaalenii_PYR-1       TLTGIQRGTFADTHGWMARLS
MMAR_3255|M.marinum_M               TLTGIQRGTFADTHGWMSRLS
MUL_3570|M.ulcerans_Agy99           TLTGIQRGTFADTHGWMSRLS
Mb2233c|M.bovis_AF2122/97           TLTGIQRGTFADTHGWMARLG
Rv2210c|M.tuberculosis_H37Rv        TLTGIQRGTFADTHGWMARLG
MLBr_00866|M.leprae_Br4923          TLTGIQRGTFADTHGWMARLG
MAV_2281|M.avium_104                TLTGIQRGTFADTHGWMTRLG
MSMEG_4276|M.smegmatis_MC2_155      TLTGIQRGTFADTHGWMARLN
MAB_1950|M.abscessus_ATCC_1997      TLTGIQRGTFADTHGWITQLG
                                    ****************:::*.