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M. tuberculosis H37Rv Rv1202 (dapE)

annotation: dipeptidase
coordinates: 1345260 - 1346324
length: 354

VLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNGNAVLARTKLNRSSRVLLAGHL
DTVPVAGNLPSRRENDQLHGCGAADMKSGDAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRE
LPDWLSADVAILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLDRLAVYRARSVD
IDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPDRSVAAALQHVHDVFDGLDVQIEQTDAAAGAL
PGLSEPAAKALVEAAGGQVRAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLRR
YLGG
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv1202dapE-100% (354)dipeptidase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1234dapE0.0100.00% (354) succinyl-diaminopimelate desuccinylase
M. gilvum PYR-GCKMflv_2180-1e-16078.25% (354) dipeptidase
M. leprae Br4923MLBr_01059dapE1e-17887.01% (354) succinyl-diaminopimelate desuccinylase
M. abscessus ATCC 19977MAB_1336-1e-15578.35% (351) succinyl-diaminopimelate desuccinylase
M. marinum MMMAR_4235dapE0.090.06% (352) succinyl-diaminopimelate desuccinylase DapE
M. avium 104MAV_1349dapE1e-17385.03% (354) dipeptidase
M. smegmatis MC2 155MSMEG_5103dapE1e-15978.06% (351) dipeptidase
M. thermoresistible (build 8)TH_1840dapE1e-16078.19% (353) PROBABLE SUCCINYL-DIAMINOPIMELATE DESUCCINYLASE DAPE
M. ulcerans Agy99MUL_0954dapE0.090.06% (352) succinyl-diaminopimelate desuccinylase
M. vanbaalenii PYR-1Mvan_4515-1e-15978.25% (354) dipeptidase

CLUSTAL 2.0.9 multiple sequence alignment


Rv1202|M.tuberculosis_H37Rv         -MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNG
Mb1234|M.bovis_AF2122/97            -MLDLRGDPIELTAALIDIPSESRKEARIADEVEAALRAQASGFEIIRNG
MMAR_4235|M.marinum_M               -MLDLRGDPIDLTAALIDIPSESRDEARIADEVEAALRAQTSGFEIIRNG
MUL_0954|M.ulcerans_Agy99           -MLDLRGDPIDLTAALIDIPSESRDEARIADEVEAALRAQTSGFEIIRNG
MLBr_01059|M.leprae_Br4923          -MLDLRGDPIELTAALVDIPSESRAEARIADAVETALRAQTAGFEIVRNG
MAV_1349|M.avium_104                -MLDLTGDPVALTAALVDIPSESRDEARLADEVEAALRSQTSGFEIVRNG
Mflv_2180|M.gilvum_PYR-GCK          -MLDLHADPIALTAALVDIPSESRHEARIADAIEAALREQTTGFEVVRNG
Mvan_4515|M.vanbaalenii_PYR-1       -MLDLHGDPIALTAALVDIPSESRHEKRIADEIETALREQTAGFEIVRNG
MSMEG_5103|M.smegmatis_MC2_155      MGLDLSADPIALTAALVDIPSVSRDERRIADEIEAALRAQAPHFEVIRNG
TH_1840|M.thermoresistible__bu      VALDLHGDPIALTAALVDIPSESRHEQRIADEIETALREQTRGFEVIRNG
MAB_1336|M.abscessus_ATCC_1997      MALELAGDPIALTAALVDIPSESRHEAQIADAVEVALREQTSGFEVIRNG
                                      *:* .**: *****:**** ** * ::** :*.*** *:  **::***

Rv1202|M.tuberculosis_H37Rv         NAVLARTKLNRSSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSG
Mb1234|M.bovis_AF2122/97            NAVLARTKLNRSSRVLLAGHLDTVPVAGNLPSRRENDQLHGCGAADMKSG
MMAR_4235|M.marinum_M               NAVLARTRLNRPSRVLLAGHLDTVPVADNLPSRRADGQLHGCGAADMKSG
MUL_0954|M.ulcerans_Agy99           NAVLARTRLNRPSRVLLAGHLDTVPVADNLPSRRADGQLHGCGAADMKSG
MLBr_01059|M.leprae_Br4923          NAVLARTSLHRPARVLLAGHLDTVPVAGNLPSRCEKDVLHGCGTVDMKSG
MAV_1349|M.avium_104                NAVLARTDRGRPSRVLLAGHLDTVPVAGNLPSRREDGDLYGCGTADMKSG
Mflv_2180|M.gilvum_PYR-GCK          DAVLARTHFGRPSRVLLAGHTDTVPAADNLPSRLADGILHGCGTSDMKSG
Mvan_4515|M.vanbaalenii_PYR-1       DAVLARTDFGRPSRVLLAGHIDTVPAADNLPSRLADGVLHGCGTSDMKAG
MSMEG_5103|M.smegmatis_MC2_155      DAVLARTNLGRPSRVMLAGHIDTVPIADNLPSRIVDGEMYGCGTSDMKAG
TH_1840|M.thermoresistible__bu      NAVLARTNHGRPTRVLLAGHTDTVPAADNLPSRRVGDLLYGCGTSDMKSG
MAB_1336|M.abscessus_ATCC_1997      NAVLARTNNGLGTRVMLAGHLDTVPAADNVPSRHEGEILHGCGTVDMKSG
                                    :******     :**:**** **** *.*:***     ::***: ***:*

Rv1202|M.tuberculosis_H37Rv         DAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADV
Mb1234|M.bovis_AF2122/97            DAVFLHLAATLAEPTHDLTLVFYDCEEIDSAANGLGRIQRELPDWLSADV
MMAR_4235|M.marinum_M               DAVFLHLAATVAEPVHDLTLVFYDCEEIEAAANGLGRIERELPEWLSADV
MUL_0954|M.ulcerans_Agy99           DAVFLHLAATVAEPVHDLTLVFYDCEEIEAAANGLGRIERELPEWLSADV
MLBr_01059|M.leprae_Br4923          DAVFLHLAATVTEPVHDLTLMFYDCEEIDSAANGLVRIERELPEWLAADV
MAV_1349|M.avium_104                DAVFLHLAATVADPAHDLTLVMYDCEEIDAAANGLGRIQRELPDWLSADV
Mflv_2180|M.gilvum_PYR-GCK          DAVFLHLAATVVDPAHDITLVMYDCEEIEASANGLGRIERELPEWLAADV
Mvan_4515|M.vanbaalenii_PYR-1       DAVFLHLAATVAEPAHDITLVMYDCEEIEASANGLGRIERELPEWLAADV
MSMEG_5103|M.smegmatis_MC2_155      DAVFLHLAATITEPTHDITLVMYDCEEIESSANGLGRIERELRDWLTADV
TH_1840|M.thermoresistible__bu      DAVFLHLAATVTEPAHDITLVMYDCEEIEAAANGLGRIERELPDWLRADV
MAB_1336|M.abscessus_ATCC_1997      DAVFLHLAATVT-PRVDLTLVFYDCEEIESSANGLGRIERELPDWLDADL
                                    **********:. *  *:**::******:::**** **:*** :** **:

Rv1202|M.tuberculosis_H37Rv         AILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLD
Mb1234|M.bovis_AF2122/97            AILGEPTAGCIEAGCQGTLRVVLSVTGTRAHSARSWLGDNAIHKLGAVLD
MMAR_4235|M.marinum_M               AILGEPTSGYIEAGCQGTLRVVISATGTRAHSARSWLGDNAIHKLSAVLD
MUL_0954|M.ulcerans_Agy99           AILGEPTSGYIEAGCQGTLRVVISATGTRAHSARSWLGDNAIHKLSAVLD
MLBr_01059|M.leprae_Br4923          AILGEPTGGYIEAGCQGTLRVVINAAGSRAHSARSWLGDNAIHKLGAVLD
MAV_1349|M.avium_104                AILGEPTGGYIEAGCQGTLRVVVSATGTRAHSARSWLGDNAIHKLGAVLQ
Mflv_2180|M.gilvum_PYR-GCK          AILGEPSGGYIEAGCQGTLRVVVRATGTRAHSARSWLGDNAVHKLGDVLA
Mvan_4515|M.vanbaalenii_PYR-1       AILGEPSGGLIEAGCQGTLRVIVRATGTRAHSARSWLGDNAIHKLSDVLA
MSMEG_5103|M.smegmatis_MC2_155      AILGEPSGGYIEAGCQGTIRVVISAKGTRAHSARSWLGDNAIHKLAPVLD
TH_1840|M.thermoresistible__bu      AILGEPSGGFIEAGCQGTLRMVISTTGTRAHSARSWLGDNAIHKLAPVLD
MAB_1336|M.abscessus_ATCC_1997      AILGEPTAGLIEAGCQGTLRVVIRTRGTRAHSARSWLGDNAIHKLAAVLD
                                    ******:.* ********:*::: . *:*************:***. ** 

Rv1202|M.tuberculosis_H37Rv         RLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPD
Mb1234|M.bovis_AF2122/97            RLAVYRARSVDIDGCTYREGLSAVRVAGGVAGNVIPDAASVTINYRFAPD
MMAR_4235|M.marinum_M               RLARYPARSVDIDGCTYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPD
MUL_0954|M.ulcerans_Agy99           RLARYPARSVDIDGCTYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPD
MLBr_01059|M.leprae_Br4923          RLAAYRARTVDIDGCVYREGLSAVRVDGGVAGNVIPDAASVTVNYRFAPD
MAV_1349|M.avium_104                RLAGYQARSVEIDGCTYREGLSAVRIDGGVAGNVIPDAAAVTVNFRFAPD
Mflv_2180|M.gilvum_PYR-GCK          RLTAYRARSVDIDGCTYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPD
Mvan_4515|M.vanbaalenii_PYR-1       RLRSYQARSVDIDGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPD
MSMEG_5103|M.smegmatis_MC2_155      RLASYQARSVDIDGCVYREGLSAVRIDGGIAGNVIPDAASVTVNFRFAPD
TH_1840|M.thermoresistible__bu      RLSDYRARSVDIDGCVYREGLSAVRIDGGVAGNVIPDAASVTVNFRFAPD
MAB_1336|M.abscessus_ATCC_1997      RLAAYRARIVDIDGCQYREGLSAVRIDGGVAGNVIPDEAAVTVNFRFAPD
                                    **  * ** *:**** *********: **:******* *:**:*:*****

Rv1202|M.tuberculosis_H37Rv         RSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQV
Mb1234|M.bovis_AF2122/97            RSVAAALQHVHDVFDGLDVQIEQTDAAAGALPGLSEPAAKALVEAAGGQV
MMAR_4235|M.marinum_M               RSVPAALQHVREVFDGLDVQIEQTDAAAGALPGLAQPAAKALVEAAGGQV
MUL_0954|M.ulcerans_Agy99           RSVPAALQHVREVFDGLDVQIEQTDAAAGALPGLAQPAAKALVEAAGGQV
MLBr_01059|M.leprae_Br4923          RSVAAALRHVHDVFDGLDVQIEQTDAAVGALPGLSQPAAKALVEAADGQV
MAV_1349|M.avium_104                RSPAEALQHVRDVLDGLDVRIEQTDAAAGALPGLSQPAAKALVEAAGGRV
Mflv_2180|M.gilvum_PYR-GCK          RTIEQAHAHVLEVFDGLDVEIELTDSAAGALPGLSRPAAAALVEAAGGQV
Mvan_4515|M.vanbaalenii_PYR-1       RSVEQAYAHVREVFDRLDVTIELTDAAAGALPGLTRPAAAALVEAAGGQV
MSMEG_5103|M.smegmatis_MC2_155      RDVDQAVAHVHEVFDGLDVTLELTDAAAGALPGLTQPAAAALVAAAGGQV
TH_1840|M.thermoresistible__bu      RTVEQAERHVREVFDGLDVRMELTDAAGGALPGLQQPAAAQLVAAAGGQV
MAB_1336|M.abscessus_ATCC_1997      RSPEQALVHVHEVFDGLDVQIELTDSAAGALPGLDRPAAAELVGAAGGVV
                                    *    *  ** :*:* *** :* **:* ****** .***  ** **.* *

Rv1202|M.tuberculosis_H37Rv         RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLR
Mb1234|M.bovis_AF2122/97            RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVGNITAAVDLLR
MMAR_4235|M.marinum_M               RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVATITTVADTLR
MUL_0954|M.ulcerans_Agy99           RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHCRDERVPVATITTVADTLR
MLBr_01059|M.leprae_Br4923          RAKYGWTDVSRFAALGVPAVNYGPGDPNLAHRHDERVPVVQITAAVDMLR
MAV_1349|M.avium_104                RAKYGWTDVARFAALGIPALNFGPGDPNLAHRRDERVAVAAITAAADLLR
Mflv_2180|M.gilvum_PYR-GCK          RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHRVDEHVEVAQITAVTDMLR
Mvan_4515|M.vanbaalenii_PYR-1       RAKYGWTDVSRFAALGIPAVNYGPGDPNLAHRVDESVDVAQITAVTDMLR
MSMEG_5103|M.smegmatis_MC2_155      RAKYGWTDVARFAALGIPAVNYGPGDPNLAHRVDERVQVAAITAAADMLR
TH_1840|M.thermoresistible__bu      RAKYGWTDVARFAALGVPAVNYGPGDPNLAHKSDEHVDVTAITAVTDVLR
MAB_1336|M.abscessus_ATCC_1997      RAKYGWTDVSRFAARGIAAVNYGPGDPNLAHTRGEHVPVQQITAVTEVLR
                                    *********:**** *:.*:*:*********  .* * *  **:..: **

Rv1202|M.tuberculosis_H37Rv         RYLGG
Mb1234|M.bovis_AF2122/97            RYLGG
MMAR_4235|M.marinum_M               RYLST
MUL_0954|M.ulcerans_Agy99           RYLST
MLBr_01059|M.leprae_Br4923          RYLGG
MAV_1349|M.avium_104                GYLSG
Mflv_2180|M.gilvum_PYR-GCK          RYLIG
Mvan_4515|M.vanbaalenii_PYR-1       RYLIG
MSMEG_5103|M.smegmatis_MC2_155      TYLTT
TH_1840|M.thermoresistible__bu      RYLSG
MAB_1336|M.abscessus_ATCC_1997      RYLTV
                                     **