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AELTISASDIEGAIEDYVSSFTADSGREEIGVVIDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDE HSVGAVILGEFEKIEQGQQVKRTGEVLSVPVGDAFLGRVINPLGQPIDGQGDIEAEGRRALELQAPSVVQ RQGVSEPLQTGIKAIDSMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWATGDPKQQVRCVYVAIGQ KGTTIASVKRALEEGGAMECTTIVAAPASDAAGFKWLAPYTGSAIGQHWMYDGKHVLIVFDDLSKQADAY RAISLLLRRPPGREAFPGDVFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITDG QCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLELSQYRELEAFAAFASDLDAASKAQL DRGARLVELLKQPQYTPYPVEDQVVAIYLGTGGHLDSVPVEDVARFESELLEHVKASHGDILAGIRESKK LSEEAEQKLANVINEFKKGFSASDGSSVVVNEAEAEAMDEADVEKESVKVRKPAPKK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4330 | - | - | 100% (548) | F0F1 ATP synthase subunit alpha |
| M. vanbaalenii PYR-1 | Mvan_4328 | - | 7e-20 | 22.82% (412) | F0F1 ATP synthase subunit beta |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1340 | atpA | 0.0 | 83.39% (548) | F0F1 ATP synthase subunit alpha |
| M. gilvum PYR-GCK | Mflv_2316 | - | 0.0 | 94.71% (548) | F0F1 ATP synthase subunit alpha |
| M. tuberculosis H37Rv | Rv1308 | atpA | 0.0 | 83.39% (548) | F0F1 ATP synthase subunit alpha |
| M. leprae Br4923 | MLBr_01143 | atpA | 0.0 | 82.12% (548) | F0F1 ATP synthase subunit alpha |
| M. abscessus ATCC 19977 | MAB_1451 | - | 0.0 | 84.12% (548) | F0F1 ATP synthase subunit alpha |
| M. marinum M | MMAR_4089 | atpA | 0.0 | 85.58% (548) | ATP synthase alpha chain AtpA |
| M. avium 104 | MAV_1525 | atpA | 0.0 | 86.13% (548) | F0F1 ATP synthase subunit alpha |
| M. smegmatis MC2 155 | MSMEG_4938 | atpA | 0.0 | 93.25% (548) | F0F1 ATP synthase subunit alpha |
| M. thermoresistible (build 8) | TH_1560 | atpA | 0.0 | 84.85% (548) | ATP synthase F1, alpha subunit |
| M. ulcerans Agy99 | MUL_3956 | atpA | 0.0 | 85.04% (548) | F0F1 ATP synthase subunit alpha |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_4330|M.vanbaalenii_PYR-1 MAELTISASDIEGAIEDYVSSFTADSGREEIGVVIDAGDGIAHVEGLPSV
Mflv_2316|M.gilvum_PYR-GCK MAELIISASDIEGAIEDYVSSFTADSEREEIGTVIDAGDGIAHVEGLPSV
MSMEG_4938|M.smegmatis_MC2_155 MAELTISAADIEGAIEDYVSSFSADTEREEIGTVIDAGDGIAHVEGLPSV
MMAR_4089|M.marinum_M MAELTISANDIQSAIEEYVGSFTSDTSREEVGTVVDAGDGIAHVEGLPSV
MUL_3956|M.ulcerans_Agy99 MAELTISANDIQSAIEEYVGSFTSDTSREEVGTVVDAGDGIAHVEGLPSV
MAV_1525|M.avium_104 MAELTISADDIQSAIEEYVGSFTSDTSREEVGTVVDAGDGIAHVEGLPSV
Mb1340|M.bovis_AF2122/97 MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSV
Rv1308|M.tuberculosis_H37Rv MAELTIPADDIQSAIEEYVSSFTADTSREEVGTVVDAGDGIAHVEGLPSV
MLBr_01143|M.leprae_Br4923 MAELTISADDIQNAIEEYVSSFTADTFREEVGTVVDVGDSIAHVEGLPSV
TH_1560|M.thermoresistible__bu MADLTISAADIQGAIEDYVASFESATEREETGTVVDAGDGIAHVEGLPSV
MAB_1451|M.abscessus_ATCC_1997 MTELTISSADISGAIEQYVATFSADPTREEIGIVSDAGDGIAHVEGLPSV
*::* *.: **..***:**.:* : . *** * * *.**.**********
Mvan_4330|M.vanbaalenii_PYR-1 MTQELLEFPGGVLGVALNLDEHSVGAVILGEFEKIEQGQQVKRTGEVLSV
Mflv_2316|M.gilvum_PYR-GCK MTQELLEFPGGVLGVALNLDEHSVGAVILGEFEKIEEGQQVKRTGEVLSV
MSMEG_4938|M.smegmatis_MC2_155 MTQELLEFPGGVLGVALNLDEHSVGAVILGEFEKIEEGQQVKRTGEVLSV
MMAR_4089|M.marinum_M MTQELLEFPGGVLGVALNLDEHSVGAVILGNFENIEEGQQVKRTGEVLSV
MUL_3956|M.ulcerans_Agy99 MTQELLEFPGGVLGVALNLDEHSVGAVILGNSENIEEGQQVKRTGEVLSV
MAV_1525|M.avium_104 MTQELLEFPGGVLGVALNLDEHSVGAVILGDFEKIEEGQQVKRTGEVLSV
Mb1340|M.bovis_AF2122/97 MTQELLEFPGGILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSV
Rv1308|M.tuberculosis_H37Rv MTQELLEFPGGILGVALNLDEHSVGAVILGDFENIEEGQQVKRTGEVLSV
MLBr_01143|M.leprae_Br4923 MTQELLEFPGGILGVALNLDEHNVGAVILGDFENIKEGQKVKRTGDVLSV
TH_1560|M.thermoresistible__bu MAQELLEFPGGVLGVALNLDENEIGAVILGDFEKIEQGQQVRRTGEVLSV
MAB_1451|M.abscessus_ATCC_1997 MTQELLEFPGGVLGVALNLDERSVGTVVLGDFQDIEEGQQVKRTGEVLSV
*:*********:*********..:*:*:**: :.*::**:*:***:****
Mvan_4330|M.vanbaalenii_PYR-1 PVGDAFLGRVINPLGQPIDGQGDIEAEGRRALELQAPSVVQRQGVSEPLQ
Mflv_2316|M.gilvum_PYR-GCK PVGDAFLGRVINPLGQPIDGQGDIESDTRRALELQAPSVVQRQGVSEPLQ
MSMEG_4938|M.smegmatis_MC2_155 PVGDAFLGRVVNPLGQPIDGQGDIAAETRRALELQAPSVVQRQSVSEPLQ
MMAR_4089|M.marinum_M PVGDAFLGRVINPLGQPIDGRGDIEAETRRALELQAPSVVQRQSVKEPLQ
MUL_3956|M.ulcerans_Agy99 PVGDAFLGRVINPLGQPIDGRGDIKAETRRALELQAPSVVQRQSVKEPLQ
MAV_1525|M.avium_104 PVGDAFLGRVVNPLGQPIDGQGDIETDIRRALEIQAPSVVQRQSVKEPLQ
Mb1340|M.bovis_AF2122/97 PVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQ
Rv1308|M.tuberculosis_H37Rv PVGDGFLGRVVNPLGQPIDGRGDVDSDTRRALELQAPSVVHRQGVKEPLQ
MLBr_01143|M.leprae_Br4923 PVGEAFMGRVVNPLGQPIDGRGDIEAEARRALELQAPSVVQRQSVKEPLQ
TH_1560|M.thermoresistible__bu PVGDGYLGRVVNPLGQPIDGKGDIETTGRRALELQAPSVVQRQSVFEPLQ
MAB_1451|M.abscessus_ATCC_1997 PVGDAFLGRVINPLGQPIDGRGDIEAETRRALELQAPSVVQRQSVSEPLQ
***:.::***:*********:**: : *****:******:**.* ****
Mvan_4330|M.vanbaalenii_PYR-1 TGIKAIDSMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWATGDPKQ
Mflv_2316|M.gilvum_PYR-GCK TGIKAIDSQTPIGRGQRQLIIGDRKTGKTAVAVDTILNQRKAWETGDPKQ
MSMEG_4938|M.smegmatis_MC2_155 TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQREAWLTGDPKQ
MMAR_4089|M.marinum_M TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPKK
MUL_3956|M.ulcerans_Agy99 TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWETGDPKK
MAV_1525|M.avium_104 TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDEKK
Mb1340|M.bovis_AF2122/97 TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKK
Rv1308|M.tuberculosis_H37Rv TGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDPKK
MLBr_01143|M.leprae_Br4923 TGIKAIDAMTPIGRGQRQLVIGDRKTGKTAVCVDTILNQRQNWESGDPKR
TH_1560|M.thermoresistible__bu TGIKAIDSMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRANWETGDSKQ
MAB_1451|M.abscessus_ATCC_1997 TGIKAIDSQTPIGRGQRQLIIGDRKTGKTAVCIDTILNQKQAWETGDPAQ
*******: **********:***********.:******: * :** :
Mvan_4330|M.vanbaalenii_PYR-1 QVRCVYVAIGQKGTTIASVKRALEEGGAMECTTIVAAPASDAAGFKWLAP
Mflv_2316|M.gilvum_PYR-GCK QVRCVYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAP
MSMEG_4938|M.smegmatis_MC2_155 QVRCVYVAIGQKGTTIASVKRALEEGGAMEYTTIVAAPASDAAGFKWLAP
MMAR_4089|M.marinum_M QVRCVYVAVGQKGTTIASVRRALEEGGAMDYTTIVAAPASDSAGFKWLAP
MUL_3956|M.ulcerans_Agy99 QVRCVYVAVGQKGTTIASVRRALEEGGAMDYTTIVAAPASDSAGFKWLAP
MAV_1525|M.avium_104 QVRCVYVAIGQKGTTIASVRRALEEGGAMDYTTIVAAPASDSAGFKWLAP
Mb1340|M.bovis_AF2122/97 QVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAASESAGFKWLAP
Rv1308|M.tuberculosis_H37Rv QVRCVYVAIGQKGTTIAAVRRTLEEGGAMDYTTIVAAAASESAGFKWLAP
MLBr_01143|M.leprae_Br4923 QVRCVYVAIGQKGTTIASVRRALEEGGAMDYTTIVAALASDSAGFKWLAP
TH_1560|M.thermoresistible__bu QVRCVYVAIGQKGTTIASVRQTLEEGGAMDYTTIVAAPASDSAGFKWLAP
MAB_1451|M.abscessus_ATCC_1997 QVRCIYVAVGQKGSTVAAVRRTLDEAGALEYTTIVAAPASDAAGFKWLAP
****:***:****:*:*:*:::*:*.**:: ****** **::********
Mvan_4330|M.vanbaalenii_PYR-1 YTGSAIGQHWMYDGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGD
Mflv_2316|M.gilvum_PYR-GCK YTGSAIGQHWMYDGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGD
MSMEG_4938|M.smegmatis_MC2_155 YTGSAIGQHWMYNGKHVLIVFDDLSKQADAYRAISLLLRRPPGREAFPGD
MMAR_4089|M.marinum_M YTGSAVAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
MUL_3956|M.ulcerans_Agy99 YTGSAVAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
MAV_1525|M.avium_104 YTGSAIAQHWMYDGKHVLIVFDDLSKQAEAYRAISLLLRRPPGREAYPGD
Mb1340|M.bovis_AF2122/97 YTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGD
Rv1308|M.tuberculosis_H37Rv YTGSAIAQHWMYEGKHVLIIFDDLTKQAEAYRAISLLLRRPPGREAYPGD
MLBr_01143|M.leprae_Br4923 YTGSAIAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
TH_1560|M.thermoresistible__bu YTGSAIAQHWMYDGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
MAB_1451|M.abscessus_ATCC_1997 YTGSALGQHWMYQGKHVLIVFDDLTKQAEAYRAISLLLRRPPGREAYPGD
*****:.*****:******:****:***:*****************:***
Mvan_4330|M.vanbaalenii_PYR-1 VFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITD
Mflv_2316|M.gilvum_PYR-GCK VFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITD
MSMEG_4938|M.smegmatis_MC2_155 VFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAFIPTNVISITD
MMAR_4089|M.marinum_M VFYLHSRLLERCAKLSDELGGGSLTGLPIIETKANDISAYIPTNVISITD
MUL_3956|M.ulcerans_Agy99 VFYLHSRLLERCAKLSDELGGGSLTGLPIIETKANDISAYIPTNVISITD
MAV_1525|M.avium_104 VFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAYIPTNVISITD
Mb1340|M.bovis_AF2122/97 VFYLHSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITD
Rv1308|M.tuberculosis_H37Rv VFYLHSRLLERCAKLSDDLGGGSLTGLPIIETKANDISAYIPTNVISITD
MLBr_01143|M.leprae_Br4923 VFYLHSRLLERCAKLADHLGGGSLTGLPIIETKANDISAYIPTNVISITD
TH_1560|M.thermoresistible__bu VFYLHSRLLERCAKLSDDLGGGSLTGLPVIETKANDISAYIPTNVISITD
MAB_1451|M.abscessus_ATCC_1997 VFYLHSRLLERCAKLSDELGAGSLTGLPIIETKANDISAYIPTNVISITD
***************:*.**.**:****:**********:**********
Mvan_4330|M.vanbaalenii_PYR-1 GQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLELSQY
Mflv_2316|M.gilvum_PYR-GCK GQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLELSQY
MSMEG_4938|M.smegmatis_MC2_155 GQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
MMAR_4089|M.marinum_M GQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
MUL_3956|M.ulcerans_Agy99 GQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAIKEVAGSLRLDLSQY
MAV_1525|M.avium_104 GQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQF
Mb1340|M.bovis_AF2122/97 GQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
Rv1308|M.tuberculosis_H37Rv GQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
MLBr_01143|M.leprae_Br4923 GQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQY
TH_1560|M.thermoresistible__bu GQCFLETDLFNQGVRPAINVGVSVSRVGGAAQIKAMKDVAGSLRLDLSQY
MAB_1451|M.abscessus_ATCC_1997 GQCFLQTDLFNQGVRPAVNVGVSVSRVGGAAQIKAMKEVAGSLRLELSQY
*****::**********:*****************:*:*******:***:
Mvan_4330|M.vanbaalenii_PYR-1 RELEAFAAFASDLDAASKAQLDRGARLVELLKQPQYTPYPVEDQVVAIYL
Mflv_2316|M.gilvum_PYR-GCK RELESFAAFASDLDAASKAQLDRGARLVELLKQPQYTPYSVEDQVVAIFL
MSMEG_4938|M.smegmatis_MC2_155 RELEAFAAFASDLDAASKAQLDRGARLVELLKQPQYSPLAVEEQVVAIFL
MMAR_4089|M.marinum_M RELEAFAAFASDLDATSKAQLDRGARLVELLKQPQYQPMPVEEQVISIFL
MUL_3956|M.ulcerans_Agy99 RELEAFAAFASDLDATSKAQLDRGARLVELLKQPQYQPMPVEEQVISIFL
MAV_1525|M.avium_104 RELEAFAAFASDLDATSKAQLDRGARLVELLKQPQYQPMPVEEQVVSIFL
Mb1340|M.bovis_AF2122/97 RELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFL
Rv1308|M.tuberculosis_H37Rv RELEAFAAFASDLDAASKAQLERGARLVELLKQPQSQPMPVEEQVVSIFL
MLBr_01143|M.leprae_Br4923 RELEAFAAFASDLDATSKAQLERGARLVELLKQPQYQPMPVEEQVISLFL
TH_1560|M.thermoresistible__bu RELEAFAAFASDLDATSKAQLDRGARLVEVLKQPQNSPMPVEDQVVAIFL
MAB_1451|M.abscessus_ATCC_1997 RELEAFAAFASDLDATSKAQLERGARLVELLKQPQNSPYPVEEQVVAIYL
****:**********:*****:*******:***** * .**:**::::*
Mvan_4330|M.vanbaalenii_PYR-1 GTGGHLDSVPVEDVARFESELLEHVKASHGDILAGIRESKKLSEEAEQKL
Mflv_2316|M.gilvum_PYR-GCK GTKGHLDSVPVEDVSRFEQEVLEHVKASHDDILQEIRETKKLSESTEEKL
MSMEG_4938|M.smegmatis_MC2_155 GTQGHLDSVPVEDVQRFESELLEHVKASHSDIFDGIRETKKLSEEAEEKL
MMAR_4089|M.marinum_M GTGGHLDSVPVEDVRRFETELLDHIRASEENLLSTIRDTQKLTEETEEAL
MUL_3956|M.ulcerans_Agy99 GTGGHLDSVPVEDVRRFETELLDHIRASEENLLSTIRDTQKLTEETEEAL
MAV_1525|M.avium_104 GTGGHLDSVPVEDVRRFETELLDHMRASEDKILAGIRDTQKLSDEAAEEL
Mb1340|M.bovis_AF2122/97 GTGGHLDSVPVEDVRRFETELLDHMRASEEEILTEIRDSQKLTEEAADKL
Rv1308|M.tuberculosis_H37Rv GTGGHLDSVPVEDVRRFETELLDHMRASEEEILTEIRDSQKLTEEAADKL
MLBr_01143|M.leprae_Br4923 GTGGHLDSVPVGDVRRFETELLDHIRVAQEEILTEIRESQKLTDEAADSL
TH_1560|M.thermoresistible__bu GTKGHLDSVPIEDVQRFEAEFLEHVKASHQEILTDIRDSKKLSDETAEKL
MAB_1451|M.abscessus_ATCC_1997 GTGGHLDSVPVEDVMRFEQEFLDHVRGSHADILADIRETKKFSEDTETKL
** *******: ** *** *.*:*:: :. .:: **:::*:::.: *
Mvan_4330|M.vanbaalenii_PYR-1 ANVINEFKKGFSASDGSSVVVNEAEAEAMDEADVEKESVKVRKPAPKK--
Mflv_2316|M.gilvum_PYR-GCK TNVINDFKKGFSASDGSSVVVNEADAEAMDEADVEKESVKVRKPAPKK--
MSMEG_4938|M.smegmatis_MC2_155 VSVINEFKKGFQASDGSSVVVSEN-AEALDPEDLEKESVKVRKPAPKKA-
MMAR_4089|M.marinum_M TKVINHFKKGFASSTGESVVPDEH-VEAMDEEDLGKESVKVKKPAPQKKK
MUL_3956|M.ulcerans_Agy99 TKVINHFKKGFASSTGESVVPDEH-VEAMDEEDLGKESVKVKKPAPQKKK
MAV_1525|M.avium_104 EKVINNFKKGFAATGGASVVPDEH-VEALDEEELEKESVKVKKPAPEKKA
Mb1340|M.bovis_AF2122/97 TEVIKNFKKGFAATGGGSVVPDEH-VEALDEDKLAKEAVKVKKPAPKKKK
Rv1308|M.tuberculosis_H37Rv TEVIKNFKKGFAATGGGSVVPDEH-VEALDEDKLAKEAVKVKKPAPKKKK
MLBr_01143|M.leprae_Br4923 TEVIKSFKKGFAATGGASVVPNEH-VAALDEEKLDKESVKVHQAIPAKTS
TH_1560|M.thermoresistible__bu VNVVNEFKKGFSTTSGESVIPDEG-VEAMDEADLEKESVQVRKPPPPKKK
MAB_1451|M.abscessus_ATCC_1997 TNAVNAFKKSFAATDGSSVEVKGVAAEALDESAVGQETVQVRKPAPKK--
..:: ***.* :: * ** . . *:* : :*:*:*::. * *
Mvan_4330|M.vanbaalenii_PYR-1 ---------
Mflv_2316|M.gilvum_PYR-GCK ---------
MSMEG_4938|M.smegmatis_MC2_155 ---------
MMAR_4089|M.marinum_M ---------
MUL_3956|M.ulcerans_Agy99 ---------
MAV_1525|M.avium_104 KKEQK----
Mb1340|M.bovis_AF2122/97 ---------
Rv1308|M.tuberculosis_H37Rv ---------
MLBr_01143|M.leprae_Br4923 EKSKNSTPR
TH_1560|M.thermoresistible__bu ---------
MAB_1451|M.abscessus_ATCC_1997 ---------