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MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYRELVETNTTASQGSCTEAAQKM AARLKGAGYADKDLVFFSPPDHPKDGGLVATLGGSDAAAKPILLLAHIDVVEAKREDWKRDPFTLAEDNG YFYARGAEDDKAMAAIFVDSLMRYRTENFVPKRPIRVALTCGEEGGGQVNGAEWLHQNRPQLVDAEFVIN EGAGGDLNEDNKPVLLEIQAGQKIYQDFTLEVTDEGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDI TRAYFKAQAPLRPGEVGQAMSTIVANPQDPAAVAVLSRNPLYNAMLRTTCVPTKIEGGHANNALPQRATA NVNCRILPGPGSVQQGAQDAIVKAVNDPKITVKPAAPFRANVASVPPLTPQIVDPIKAVAGAMWPGVPLV PTMSTGATDAIYFGRTPVYGLSGIFAQPGETHAHGLDERIQVKSLYDGRAFLYQVVKLYANGA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2311 | - | - | 100% (483) | hypothetical protein MAB_2311 |
| M. abscessus ATCC 19977 | MAB_2102 | - | 3e-31 | 28.01% (432) | hypothetical protein MAB_2102 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2165c | - | 9e-34 | 29.72% (434) | hypothetical protein Mb2165c |
| M. gilvum PYR-GCK | Mflv_3037 | - | 4e-33 | 27.51% (429) | hypothetical protein Mflv_3037 |
| M. tuberculosis H37Rv | Rv2141c | - | 9e-34 | 29.72% (434) | hypothetical protein Rv2141c |
| M. leprae Br4923 | MLBr_01288 | - | 2e-34 | 28.54% (431) | hypothetical protein MLBr_01288 |
| M. marinum M | MMAR_3123 | - | 1e-35 | 27.84% (467) | hypothetical protein MMAR_3123 |
| M. avium 104 | MAV_2350 | - | 1e-32 | 28.10% (427) | hypothetical protein MAV_2350 |
| M. smegmatis MC2 155 | MSMEG_4200 | - | 9e-33 | 27.45% (459) | hypothetical protein MSMEG_4200 |
| M. thermoresistible (build 8) | TH_2370 | dapE2 | 5e-34 | 29.12% (443) | CONSERVED HYPOTHETICAL PROTEIN |
| M. ulcerans Agy99 | MUL_2373 | - | 8e-36 | 27.84% (467) | hypothetical protein MUL_2373 |
| M. vanbaalenii PYR-1 | Mvan_3489 | - | 8e-34 | 27.74% (429) | hypothetical protein Mvan_3489 |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_01288|M.leprae_Br4923 MQKTKVLRSLVVAVVGKVTVTVETDVLVNPSDDVVEVVS------RLIRF
MAV_2350|M.avium_104 ----------------MTIQSGASEVTANPSDDVVEVVS------TLIRF
Mb2165c|M.bovis_AF2122/97 ----------------MTD---ETGASSDHSDDVAQVVS------RLIRF
Rv2141c|M.tuberculosis_H37Rv ----------------MTD---ETGASSDHSDDVAQVVS------RLIRF
MMAR_3123|M.marinum_M ----------------MTQKNGETGTSTDSRDDVAEVVS------RLIRF
MUL_2373|M.ulcerans_Agy99 ----------------MTQKNGETGTSTDSRDDVAEVVS------RLIRF
Mflv_3037|M.gilvum_PYR-GCK ----------------MTGDAGGRSGGLTPSDEVVDLVS------TLIRF
Mvan_3489|M.vanbaalenii_PYR-1 -------------------------------------MS------TLIRF
MSMEG_4200|M.smegmatis_MC2_155 -----------------------MTVSAASADEVVDLVS------ALIRF
TH_2370|M.thermoresistible__bu -----------------------VTNPPQPADEVVDLVS------TLIRF
MAB_2311|M.abscessus_ATCC_1997 -MNDTMHRILTLAVAVLALASCGTTQNQGSPATTVPAVNDDRGAFRDLYR
:. :
MLBr_01288|M.leprae_Br4923 DTTNTGDPETTRGEAECAQWVASQLAEVGYQPEYLESGAP----GRGNVF
MAV_2350|M.avium_104 DTTNTGEPETTKGEAECAQWVAEQLAAVGYAPHYVESGAP----GRGNVF
Mb2165c|M.bovis_AF2122/97 DTTNSGEPGTTKGEAECARWVAEQLAEVGYQPEYVESGAP----GRGNVF
Rv2141c|M.tuberculosis_H37Rv DTTNSGEPGTTKGEAECARWVAEQLAEVGYQPEYVESGAP----GRGNVF
MMAR_3123|M.marinum_M DTTNTGEPETTKGEAECARWVAEQLAEVGYQTEYVESGAP----GRGNVF
MUL_2373|M.ulcerans_Agy99 DTTNTGEPETTKGEAECARWVAEQLAEVGYQTEYVESGAP----GRGNVF
Mflv_3037|M.gilvum_PYR-GCK DTSNTGDPATTMGEAACARWVADQLAEVGYVCEYIEAGAP----GRANVF
Mvan_3489|M.vanbaalenii_PYR-1 DTSNTGDPATTKGEADCARWVADQLAEVGYVTEYVEAGAP----GRANVF
MSMEG_4200|M.smegmatis_MC2_155 DTSNTGDPATTKGEAECAHWVAQQLEEVGYETEYVESGAP----GRGNVF
TH_2370|M.thermoresistible__bu DTSNTGDPATTRVEAEAAHWVADRLREVGYQTEYVEAGAP----GRGNVF
MAB_2311|M.abscessus_ATCC_1997 ELVETNTTASQGSCTEAAQKMAARLKGAGYADKDLVFFSPPDHPKDGGLV
: ::. . : : .*: :* :* .** . : :* ..:.
MLBr_01288|M.leprae_Br4923 ARLAGEDSSRGALLIHGHLDVVPAETAEWSVHPFSGAVEGGQVWGRGAID
MAV_2350|M.avium_104 VRLPGADSSRGALLIHGHLDVVPAEPTEWSVHPFSGAVKDGFVWGRGAVD
Mb2165c|M.bovis_AF2122/97 ARLAGADSSRGALLIHGHLDVVPAEPAEWSVHPFSGAIEDGYVWGRGAVD
Rv2141c|M.tuberculosis_H37Rv ARLAGADSSRGALLIHGHLDVVPAEPAEWSVHPFSGAIEDGYVWGRGAVD
MMAR_3123|M.marinum_M ARLRGADSSRGALLIHGHLDVVPAEAADWSVHPFSGAIEDGYVWGRGAVD
MUL_2373|M.ulcerans_Agy99 ARLRGADSSRGALLIHGHLDVVPAEAADWSVHPFSGAIEDGYVWGRGAVD
Mflv_3037|M.gilvum_PYR-GCK ARLEGADRSRGALMLHGHLDVVPAEASDWSVHPFSGAVEDGYVWGRGAVD
Mvan_3489|M.vanbaalenii_PYR-1 ARLEGADRSRGALMLHGHLDVVPAEASDWSVHPFSGAVEDGYVWGRGAVD
MSMEG_4200|M.smegmatis_MC2_155 ARLRGADPSRGALMVHGHLDVVPAEPADWSVHPFSGAVKDGYVWGRGAVD
TH_2370|M.thermoresistible__bu ARLPGADPSRGALLVHGHLDVVPAEPADWSVHPFSGAVEDGYVWGRGAVD
MAB_2311|M.abscessus_ATCC_1997 ATLGGSDAAAKPILLLAHIDVVEAKREDWKRDPFTLAEDNGYFYARGAED
. * * * : .::: .*:*** *: :*. .**: * ..* .:.*** *
MLBr_01288|M.leprae_Br4923 MKDMVGMMIVVARQLKQAGIAPPRDLVFAFVADEEHGG-SYGSQWLVDNR
MAV_2350|M.avium_104 MKDMVGMMIVVARHLKRAGIVPPRDLVFAFIADEEHGG-TFGAQWLVDNR
Mb2165c|M.bovis_AF2122/97 MKDMVGMMIVVARHLRQAAIVPPRDLVFAFVADEEHGG-KYGSHWLVDNR
Rv2141c|M.tuberculosis_H37Rv MKDMVGMMIVVARHLRQAAIVPPRDLVFAFVADEEHGG-KYGSHWLVDNR
MMAR_3123|M.marinum_M MKDMVGMMIVVARHFRRAGIVPPRDLVFAFLADEEHGG-HFGAHWLVDNR
MUL_2373|M.ulcerans_Agy99 MKDMVGMMIVVARHFRRAGIVPPRDLVFAFLADEEHGG-HFGAHWLVDNR
Mflv_3037|M.gilvum_PYR-GCK MKDMVGMILAVARHFKRSGIVPPRDLVFAFVSDEEAGG-NYGCKWLVEHR
Mvan_3489|M.vanbaalenii_PYR-1 MKDMVGMIIAVARHFKRSGIVPPRDLVFAFVSDEEAGG-NFGCKWLVENR
MSMEG_4200|M.smegmatis_MC2_155 MKDMVGMTLAVARHFKRAGIVPPRDLVFAFVADEEHGG-TYGADWLVNNR
TH_2370|M.thermoresistible__bu MKNMLGMMLAVARHFKRAGIVPPRDIVFAFLSDEEHGG-TYGAQWLVDHR
MAB_2311|M.abscessus_ATCC_1997 DKAMAAIFVDSLMRYRTENFVPKRPIRVALTCGEEGGGQVNGAEWLHQNR
* * .: : : : :.* * : .*: ..** ** *..** ::*
MLBr_01288|M.leprae_Br4923 PDLFDGVTEAIGEVGGFSLTVPCRNGGERRLYLIETAEKGMQWMRLTARG
MAV_2350|M.avium_104 PELFAGVTEAIGEVGGFSLTVPRRDGGERRLYLIETAEKGLSWMKLTARG
Mb2165c|M.bovis_AF2122/97 PDLFDGITEAIGEVGGFSLTVPRHDGGERRLYLIETAEKGIQWMRLTARG
Rv2141c|M.tuberculosis_H37Rv PDLFDGITEAIGEVGGFSLTVPRHDGGERRLYLIETAEKGIQWMRLTARG
MMAR_3123|M.marinum_M PDLFDGVTEAVGEVGGFSLTVPRRDGGERRLYLVETAEKGILWMRLTAQG
MUL_2373|M.ulcerans_Agy99 PDLFDGVTEAVGEVGGFSLTVPRRDGGERRLYLVETAEKGILWMRLTAQG
Mflv_3037|M.gilvum_PYR-GCK PDLFEGVTEAVGEVGGFSLTVPRPDGGEKRLYLVETAEKAMLWMRLTARA
Mvan_3489|M.vanbaalenii_PYR-1 PDLFDGVTEAVGEVGGFSLTVPRRDGGERRLYLVETAEKAMLWMRLTARG
MSMEG_4200|M.smegmatis_MC2_155 PDLFEGVTEAIGEVGGFSLTVPRKDGGERRLYLIETAEKGLSWMRLTARG
TH_2370|M.thermoresistible__bu PDLFTGVTEAIGEVGGFSLTVPRKDGGERRLYLVETAEKGLAWMRLTARG
MAB_2311|M.abscessus_ATCC_1997 PQLVDAEFVINEGAGG-----DLNEDNKPVLLEIQAGQKIYQDFTLEVTD
*:*. . .** :..: * :::.:* : * .
MLBr_01288|M.leprae_Br4923 RAGHGSMVHNQNAVTAVAEAVARLGRHQFPLVTTDTVVQFLAAISEETGL
MAV_2350|M.avium_104 PAGHGSMVHDQNAVTAVAEAVARLGRHQFPLVLTDTVNQFLAAVSEETGL
Mb2165c|M.bovis_AF2122/97 RAGHGSMVHDQNAVTAVCEAVARLGRHQFPLVCTDTVAQFLAVVGEETGL
Rv2141c|M.tuberculosis_H37Rv RAGHGSMVHDQNAVTAVCEAVARLGRHQFPLVCTDTVAQFLAVVGEETGL
MMAR_3123|M.marinum_M RAGHGSMVHDHNAVTTVAEAVARLGRHQFPLVITDTVAQFLHAVSEETGL
MUL_2373|M.ulcerans_Agy99 RAGHGSMVHDHNAVTTVAEAVARLGRHQFPLVITDTVAQFLHAVSEETGL
Mflv_3037|M.gilvum_PYR-GCK RAGHGSMVHDDNAVTAVAEAVAKLGRHRFPIVLTESVEQFLTAVGEETGY
Mvan_3489|M.vanbaalenii_PYR-1 RAGHGSMVHDDNAVTAVAEAVAKLGRHRFPIVLTESVEQFLTAVGEETGY
MSMEG_4200|M.smegmatis_MC2_155 RAGHGSMVHDDNAVTAIAGAVDRLGRHEFPLVLSPAVEEFLTAVAEETGY
TH_2370|M.thermoresistible__bu RAGHGSMVNDDNAVTAVAEAVARLGRHRFPLVLTESVQQFLEAVAEETGY
MAB_2311|M.abscessus_ATCC_1997 EGGHSSQPGSFNAIQALGAALNRLAATPFPVQLNDITRAYFKAQAPLRPG
.**.* . **: :: *: :*. **: . . :: . .
MLBr_01288|M.leprae_Br4923 EFDIGSPDLEGAIEKLGPMARMLK-----AVLYDTANPTVLKAGYKVNVV
MAV_2350|M.avium_104 TFDTQSGDLRGVVEKLGPMARMLK-----AVLHDTANPTMLKAGYKANVV
Mb2165c|M.bovis_AF2122/97 AFDLDSPDLAGTIDKLGPMARMLK-----AVLHDTANPTMLKAGYKANVV
Rv2141c|M.tuberculosis_H37Rv AFDLDSPDLAGTIDKLGPMARMLK-----AVLHDTANPTMLKAGYKANVV
MMAR_3123|M.marinum_M ELDPGSPDLEGTLDKLGPIARMLK-----AVLRDTANPTMLKAGYKANVI
MUL_2373|M.ulcerans_Agy99 DLDPDSPDLEGTLDKLGPIARMLK-----AVLRDTANPTMLKAGYKANVI
Mflv_3037|M.gilvum_PYR-GCK AFDPASPDIEGTVAKLGGIARIVG-----ATLRDTANPTMLKAGYKANVI
Mvan_3489|M.vanbaalenii_PYR-1 AFDPASPDIEGTVAKLGGIARIVG-----ATLRDTANPTMLNAGYKANVI
MSMEG_4200|M.smegmatis_MC2_155 TFDPNSPDLEGTIAKLGGVARIVS-----ATLRDTANPTMLKAGYKANVI
TH_2370|M.thermoresistible__bu SFDVNSPDLEGTIAKLGGVARIVG-----ATLRDTANPTMLTAGYKANVI
MAB_2311|M.abscessus_ATCC_1997 EVGQAMSTIVANPQDPAAVAVLSRNPLYNAMLRTTCVPTKIEGGHANNAL
.. : . . . :* : * * *. ** : .*: *.:
MLBr_01288|M.leprae_Br4923 PATAEAMVDCRILPG----RQAAFEAAIDELIGPDVTREWIKDLPP---Y
MAV_2350|M.avium_104 PAIAEAVVDCRILPG----RKAAFEAEIDELIGPDVTREWIKDFSS---Y
Mb2165c|M.bovis_AF2122/97 PATAEAVVDCRVLPG----RRAAFEAEVDALIGPDVTREWVSDLPS---Y
Rv2141c|M.tuberculosis_H37Rv PATAEAVVDCRVLPG----RRAAFEAEVDALIGPDVTREWVSDLPS---Y
MMAR_3123|M.marinum_M PATAEAVVDCRVLPG----RQAAFEAEVDELIGPDVSREWISELAS---Y
MUL_2373|M.ulcerans_Agy99 PATAEAVVDCRVLPG----RQAAFEAEVDELIGPDVSREWISELAS---Y
Mflv_3037|M.gilvum_PYR-GCK PATAEAVIDCRVLPG----RLADFEREVDELIGPDVKREWITNLPS---Y
Mvan_3489|M.vanbaalenii_PYR-1 PATAEAVIDCRVLPG----RLADFEREVDELIGPDVKREWITNLPS---Y
MSMEG_4200|M.smegmatis_MC2_155 PAVAEAMIDCRVLPG----RKEAFEREVDELIGPDVTRSWERDLPS---Y
TH_2370|M.thermoresistible__bu PQTAEAIVDCRVLPG----RRAAFEREVDELIGPDVERSWERDLPA---V
MAB_2311|M.abscessus_ATCC_1997 PQRATANVNCRILPGPGSVQQGAQDAIVKAVNDPKITVKPAAPFRANVAS
* * * ::**:*** : : :. : .*.: . : .
MLBr_01288|M.leprae_Br4923 ETAFDGDLVDAMNAAVLAVDPDGRTVPYMASGGTDAKAFARLGIRCFGFT
MAV_2350|M.avium_104 ETGFDGDLVDAMNDAVLALDPDARTVPYMLSGGTDAKSFARLGIRCFGFS
Mb2165c|M.bovis_AF2122/97 ETTFDGDLVAAMNAAVLAVDPDGRTVPYMLSGGTDAKAFARLGIRCFGFS
Rv2141c|M.tuberculosis_H37Rv ETTFDGDLVAAMNAAVLAVDPDGRTVPYMLSGGTDAKAFARLGIRCFGFS
MMAR_3123|M.marinum_M ETSFDGDLVDAMNAAVLSVDPDGRTVPYMLSGGTDAKAFARLGIRCFGFS
MUL_2373|M.ulcerans_Agy99 ETSFDGDLVDAMNAAVLSVDPDGRTVPYMLSGGTDAKAFARLGIRCFGFS
Mflv_3037|M.gilvum_PYR-GCK ETPFDGELLDAMNTAILANDPDARTVPYMLSGGTDAKHFARLGIRCFGFA
Mvan_3489|M.vanbaalenii_PYR-1 ETPFDGELLEAMNNAILAADPDARTVPYMMSGGTDAKHFARLGIRCFGFA
MSMEG_4200|M.smegmatis_MC2_155 ETSFDGDLVDAMNASVLTLDPEARIVPYMLSAGTDAKSFQRLGIRCFGFA
TH_2370|M.thermoresistible__bu ETTFDGELVDAMNASLLAVDPEARTVPYMMSGGTDAKAFQRLGIRCFGFV
MAB_2311|M.abscessus_ATCC_1997 VPPLTPQIVDPIKAVAGAMWPGVPLVPTMSTGATDAIYFGRT--PVYGLS
. : ::: .:: : * ** * :..*** * * :*:
MLBr_01288|M.leprae_Br4923 PLRLPPELDFTALFHGVDERVSIDALKFGIDVLAHFLTHC----
MAV_2350|M.avium_104 PLRLPPDLDFTALFHGVDERVPIDALRFGTDVLTHFLTHC----
Mb2165c|M.bovis_AF2122/97 PLRLPPDLDFTSLFHGVDERVPIDGLRFGTEVLTHLLTHC----
Rv2141c|M.tuberculosis_H37Rv PLRLPPDLDFTSLFHGVDERVPIDGLRFGTEVLTHLLTHC----
MMAR_3123|M.marinum_M PLRLPPELDFAALFHGVDERVPIDALRFGTEVLTHFLTHC----
MUL_2373|M.ulcerans_Agy99 PLRLPPELDFATLFHGVDERVPIDALRFGTEVLTHFLTHC----
Mflv_3037|M.gilvum_PYR-GCK PLRLPPDLDFAALFHGVDERVPVDALTFGAQVLEHFLLHS----
Mvan_3489|M.vanbaalenii_PYR-1 PLRLPPDLDFAALFHGVDERVPVDALTFGAQVLENFLLHS----
MSMEG_4200|M.smegmatis_MC2_155 PLRLPPDLDFAALFHGVDERVPVDALQFGAGVLEHFLQNC----
TH_2370|M.thermoresistible__bu PLRLPPELDFSALFHGVDERVPVDALEFGARVLDHFLQHC----
MAB_2311|M.abscessus_ATCC_1997 GIFAQPGE---THAHGLDERIQVKSLYDGRAFLYQVVKLYANGA
: * : **:***: :..* * .* :.: