For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TEFMRNSDAFTWAMESDPRLRSTVVTLILLDKSPDWDEVRDRFDIIARAVPMLGQRVVASPPPAPPRWEQ APDFDLDFHMRRVTASAPGTVDTLLEMARVAAMEDFDRARPLWEATLVDGLDNDGAAMILKFHHALTDGV GGIQIAMILFDLSAAHEQPAPVAALPEVPPPPWLRSYRDTAQYGAGLVGNALMGALKMAPKLVSRSILRP VDTVSSAAELAASVYRTMAPVNRRGSSLMSKRSLIRRLGVHEVPFAALRAAAHRGGGALNDAFVAGVAGG LRRYHEAHDVTVGDLHLTMPMSLREEGDEIGGNRITIMRFDVPVGVADPVERIRQVHERTGRVRHEKSVP YTQWIAGVLNMMPRWYIGSMLRNIDFLCSDVPGIPVPVFLGGAKVLAQYGFGPTIGSAVNVTLLTYVDVC TLGIDADTGAIPDFEVFFDCLVAGFDEVLALG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4103 | - | - | 100% (453) | hypothetical protein Mvan_4103 |
| M. vanbaalenii PYR-1 | Mvan_4722 | - | e-176 | 67.92% (452) | hypothetical protein Mvan_4722 |
| M. vanbaalenii PYR-1 | Mvan_4076 | - | 1e-82 | 39.91% (446) | hypothetical protein Mvan_4076 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2509c | - | 1e-81 | 40.04% (447) | hypothetical protein Mb2509c |
| M. gilvum PYR-GCK | Mflv_2004 | - | 1e-172 | 65.78% (453) | hypothetical protein Mflv_2004 |
| M. tuberculosis H37Rv | Rv2484c | - | 1e-81 | 40.04% (447) | hypothetical protein Rv2484c |
| M. leprae Br4923 | MLBr_01244 | - | 2e-72 | 34.98% (446) | hypothetical protein MLBr_01244 |
| M. abscessus ATCC 19977 | MAB_3551c | - | 5e-31 | 27.09% (406) | hypothetical protein MAB_3551c |
| M. marinum M | MMAR_2649 | - | 1e-180 | 68.36% (452) | hypothetical protein MMAR_2649 |
| M. avium 104 | MAV_1686 | - | 1e-80 | 39.15% (447) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. smegmatis MC2 155 | MSMEG_3933 | - | 1e-115 | 46.46% (452) | hypothetical protein MSMEG_3933 |
| M. thermoresistible (build 8) | TH_1039 | - | 1e-78 | 38.34% (446) | acyltransferase, ws/dgat/mgat subfamily protein |
| M. ulcerans Agy99 | MUL_3125 | - | 1e-179 | 67.92% (452) | hypothetical protein MUL_3125 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2509c|M.bovis_AF2122/97 --MAES--GESPRLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDGTP
Rv2484c|M.tuberculosis_H37Rv --MAES--GESPRLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDGTP
MAV_1686|M.avium_104 MTMTES--VETIKLSDELGPVDYLMHRGE--ANPRTRSGIMALELLDTTP
MLBr_01244|M.leprae_Br4923 --MADS--VEGIGPFDELGALDYLLHRGE--ANPRTRAGIMAVELLDTTP
TH_1039|M.thermoresistible__bu --MSDVPELDAAGLPEELSGLDQILHRGE--ANPRTRSGIMAVELLDTTP
MMAR_2649|M.marinum_M -------------MTEFMRNSDAFTWSME--SDPRLRSTVVTVLLLDRSP
MUL_3125|M.ulcerans_Agy99 --------MRGVNMTEFMRNSDAFTWSME--SDPRLRSTVVTVLLLDRSP
Mvan_4103|M.vanbaalenii_PYR-1 -------------MTEFMRNSDAFTWAME--SDPRLRSTVVTLILLDKSP
Mflv_2004|M.gilvum_PYR-GCK -------------MSEFMRNSDAFTWAME--SDPRLRSTVVTVLMLDRTP
MSMEG_3933|M.smegmatis_MC2_155 -------------MAEFLTSTDEFMWSLG--EDPVLRSTIVSLMILERAP
MAB_3551c|M.abscessus_ATCC_199 ------MGKAARIVVSRLSALDASFYSSEDSATPMHVGSLAIIRRPRGGF
. : * * . : :
Mb2509c|M.bovis_AF2122/97 DWDRFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
Rv2484c|M.tuberculosis_H37Rv DWDRFRTRFENASRRVLRLRQKVVVPTLPTAAPRWVVDPDFNLDFHVRRV
MAV_1686|M.avium_104 DWQQFRARFENASRRVLRLRQKVVVPTLPTAAPRWVIDPDFNLDFHVRRV
MLBr_01244|M.leprae_Br4923 DWNRFRSRIEDVSQRVLRLRQKVVVPTLPTAAPRWVVDPDFELDFHVRRV
TH_1039|M.thermoresistible__bu DWDRFRTRFDHASRRVLRLRQKVVMPTLPTAPARWVVDPDFNLDYHVRRV
MMAR_2649|M.marinum_M DWDEVRQRFDLISREMPMFRQRVVE-SPPPAPPRWEPDADFELDYHMRRV
MUL_3125|M.ulcerans_Agy99 DWDEVRQRFDLISREMPMFRQRVVE-SPPPASPRWEPDADFELDYHMRRV
Mvan_4103|M.vanbaalenii_PYR-1 DWDEVRDRFDIIARAVPMLGQRVVA-SPPPAPPRWEQAPDFDLDFHMRRV
Mflv_2004|M.gilvum_PYR-GCK DWGEVCGRVERLSHEVPMMRQVVVE-TPPPAPPRWQDCTDFDLDFHMRRV
MSMEG_3933|M.smegmatis_MC2_155 EWDLVVERFERLTRVAPRFRQVVSP-TVPPLPARWEEHAEFDLDWHLHRV
MAB_3551c|M.abscessus_ATCC_199 TYEELLALVESRLPQVPRYRQKVKEIGFGLARPVWLDDVDFDITYHIRRS
: . .: * * . * :*:: :*::*
Mb2509c|M.bovis_AF2122/97 RVSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVS
Rv2484c|M.tuberculosis_H37Rv RVSGPATLREVLDLAEVILQSPLDISRPLWTATLVEGMADGRAAMLLHVS
MAV_1686|M.avium_104 RVAEPGTLREVFDLAELILQSPMDISRPLWTATLVDGLADGKAATLLHVS
MLBr_01244|M.leprae_Br4923 RVPDPGTLREVFDLAEVIQQSPMDVSRPLWTATLVEGLAAGRAAMLLQIS
TH_1039|M.thermoresistible__bu RVPEPGTLRQVFDLAEVDMQSPLDISRPLWTATLVEGLRDGRAATMLHLS
MMAR_2649|M.marinum_M TVSGAGTFEDVLEMARLAEMQDFDRARALWETTLIEGLQDGGAAVICKFH
MUL_3125|M.ulcerans_Agy99 TVSGAGTFEGVLEMARLAEMQDFDRARALWKTTLIEGLQDGGAAVICKFH
Mvan_4103|M.vanbaalenii_PYR-1 TASAPGTVDTLLEMARVAAMEDFDRARPLWEATLVDGLDNDGAAMILKFH
Mflv_2004|M.gilvum_PYR-GCK AAPQDGTFESVLEMARLAQMEDFDRARPMWKLTLIEGLSDGRAAVLCCLH
MSMEG_3933|M.smegmatis_MC2_155 SAPQPRTFPVLVNLAEVAMMTDLDRTRPLWEVTLVEGMADGSAALLCKFD
MAB_3551c|M.abscessus_ATCC_199 ALPSPGSDGQLQDLVARLTSRPLDRSRPLWEMYLVEGLSKNRLAIYTKTH
. : : ::. :* :*.:* *::*: . *
Mb2509c|M.bovis_AF2122/97 HAVTDGVGGVEMFAQIYDLERDPPPRST-PPQPIPEDLSPNDLMRRGINH
Rv2484c|M.tuberculosis_H37Rv HAVTDGVGGVEMFAQIYDLERDPPPRST-PPQPIPEDLSPNDLMRRGINH
MAV_1686|M.avium_104 HAVTDGVGGVQMFAEIYDLERNPPPKPP-PPLPVPQDLSPNDLMRQGINH
MLBr_01244|M.leprae_Br4923 HAITDGVGSVEMFAEMYDLERDPPSRPR-SPQPIPQDLSRNDLMLQGINH
TH_1039|M.thermoresistible__bu HAVTDGVGGVEMFASIYDFERDPPPGKE-PPLPIPQDLTPNDLMWEGVGR
MMAR_2649|M.marinum_M HALTDGVGGVQIAMHLFDLSAEVGAHPSLPAVAELPRHSWLDGYRDSWRY
MUL_3125|M.ulcerans_Agy99 HALTDGVGGVQIAMHLFDLSAEVGAHPSLSAVAELPRHSWLDGYRDSWRY
Mvan_4103|M.vanbaalenii_PYR-1 HALTDGVGGIQIAMILFDLSAAHEQPAPVAALPEVPPPPWLRSYRDTAQY
Mflv_2004|M.gilvum_PYR-GCK HALTDGVGAVQIAMTLFGLSPELPPVDESPTAP--PQRSALGDYKDAARY
MSMEG_3933|M.smegmatis_MC2_155 HALTDGVGAVALAAALYDELEVLAASEG----------------------
MAB_3551c|M.abscessus_ATCC_199 QALVDGNSALSLGQVIFDRTARTPDFGEDIWVP------EHEPSTSELVA
:*:.** ..: : ::.
Mb2509c|M.bovis_AF2122/97 LPIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAE
Rv2484c|M.tuberculosis_H37Rv LPIAVVGGVLDALSGAVSMAGRAVLEPVSTVSGILGYARSGIRVLNRAAE
MAV_1686|M.avium_104 LPFAVVGGVVSALSGAVSVAGRAMLEPASTVSGIVGYAMSGMRVLNRAAE
MLBr_01244|M.leprae_Br4923 LPVALAGGVVGGLSGVASVAGRAILRPASTVSGVVGYVRSGIRVLSQAAE
TH_1039|M.thermoresistible__bu LPRSVVRGVRGLLGDTVRAVGKTLRDPRATVEGVLDYAASSARLVTPVAE
MMAR_2649|M.marinum_M GVSMLARALTGAIKGGPLLLYNSLRRPIVTARSAAANAASVYRTVRPLNH
MUL_3125|M.ulcerans_Agy99 GVSMLARALTGAIKGGPLLLYNSLRRPVVTARSAAANTASVYRTVRPLNH
Mvan_4103|M.vanbaalenii_PYR-1 GAGLVGNALMGALKMAPKLVSRSILRPVDTVSSAAELAASVYRTMAPVNR
Mflv_2004|M.gilvum_PYR-GCK SVGLVGSAVTGALSVAPRLVVDSVRSPRRTLGNAAGLAASVYRTVRPVNA
MSMEG_3933|M.smegmatis_MC2_155 -----SKRPSGSVAAQ---VLETIRHPLTTAATAFDTAVSIYRAARPIAG
MAB_3551c|M.abscessus_ATCC_199 GAVSEWLARPGARLEAVRNTVADVASLTGEIGELGERMVKVVRTAARGAA
. : . *
Mb2509c|M.bovis_AF2122/97 P-SPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRR
Rv2484c|M.tuberculosis_H37Rv P-SPLLRRRSLTTRTEAIDIRLADLHKAAKAGGGSINDAYLAGLCGALRR
MAV_1686|M.avium_104 P-SPLLRRRSLATRSEAIDIPLADLHKAAKAGGGSINDAYLAGLCGALRR
MLBr_01244|M.leprae_Br4923 P-SPLLRQRSLATRTEAIEIQLSDLHKAAKAGDGSINDAYLAGLVGALRR
TH_1039|M.thermoresistible__bu P-SPILRRRSLASRTGAIDIRFEDLRKAAKAGGGSINDAYLTGLCGALRL
MMAR_2649|M.marinum_M TGSPLIKERSLIRHLGVLEVPRLQLREAAHRCGGALNDAFVAGVAGGLRL
MUL_3125|M.ulcerans_Agy99 TGSPLIKERSLIRHLGVLEVPRLQLREAAHRCGGALNDAFVAGVAGGLRL
Mvan_4103|M.vanbaalenii_PYR-1 RGSSLMSKRSLIRRLGVHEVPFAALRAAAHRGGGALNDAFVAGVAGGLRR
Mflv_2004|M.gilvum_PYR-GCK TGSPLMTRRTMNRRLGILEIPMPPLRDAAHRSGGALNDAFVAGVAGGLRQ
MSMEG_3933|M.smegmatis_MC2_155 PLSPVMRRRSATRRLEILEVSRSGLRRAGDAAGGTVNDAFLAAVTGGLRR
MAB_3551c|M.abscessus_ATCC_199 PRGPLNQRVSRSRRFGVVSTKLADYRRVRAKYDCDVNDVVLATIAGALRN
..: . : : . : . . :**. :: : *.**
Mb2509c|M.bovis_AF2122/97 YHEALG---VPISTLPMAVPVNLRAEG------DAAGGNQFTGVNLAAPV
Rv2484c|M.tuberculosis_H37Rv YHEALG---VPISTLPMAVPVNLRAEG------DAAGGNQFTGVNLAAPV
MAV_1686|M.avium_104 YHEAFG---VPISTLPMAVPVNLRAEA------DTAGGNRFTGVNLAAPI
MLBr_01244|M.leprae_Br4923 YHEALG---VSISTLPMAVPVNVRTEA------DVVGSNRFVGVTLAAPL
TH_1039|M.thermoresistible__bu YHDALG---VPVDTLPMAVPVNLRSDA------DPAGGNRFTGVNLAAPI
MMAR_2649|M.marinum_M YHEKHG---VGVGDLHLTMPISLRTDD------DGMGGNRITIMRFDIPV
MUL_3125|M.ulcerans_Agy99 YHEKHG---VGVGDLHLTMPISLRTDD------DGMGGNRITIMRFDIPV
Mvan_4103|M.vanbaalenii_PYR-1 YHEAHD---VTVGDLHLTMPMSLREEG------DEIGGNRITIMRFDVPV
Mflv_2004|M.gilvum_PYR-GCK YHEKHG---AAVDALHLSMPISLRSEG------DAPGGNRITLMRFDIPA
MSMEG_3933|M.smegmatis_MC2_155 YHDHHG---VTVDQLMTSMPISVRGPH------DGIGGNRATLVRFDVPV
MAB_3551c|M.abscessus_ATCC_199 WLMSRGEPVTTASTIRAMVPMSVYRDGDLDVGGEGAATTEVSPFLVDLPV
: . . . : :*:.: : . .. . . *
Mb2509c|M.bovis_AF2122/97 GTIDPVARMKKIRAQMTQRRDEPAMNIIGSIAPVLSVLP---TAVLEGIT
Rv2484c|M.tuberculosis_H37Rv GTIDPVARMKKIRAQMTQRRDEPAMNIIGSIAPVLSVLP---TAVLEGIT
MAV_1686|M.avium_104 GTVDPVSRMKKIRAQMTQRRDEPAMNIIGSLAPVLSVLP---TAVLEGIT
MLBr_01244|M.leprae_Br4923 GTNDPAARMQKIRSQMTQRRDEPAMNIIGSLAPLMTVLP---ASVLDFIV
TH_1039|M.thermoresistible__bu GIVDPVDRMQDVRAQMTRKREERALDLLGMVAPVGSLLP---DTVLEALA
MMAR_2649|M.marinum_M GEADPAQRIKAIHERVSAVRQEKSLPHKQAIAGFLNLMP---RWYIG---
MUL_3125|M.ulcerans_Agy99 GEADPAQRIKAIHERVSAVRQEKSLPHTQAIAGFLNPMP---RWYIG---
Mvan_4103|M.vanbaalenii_PYR-1 GVADPVERIRQVHERTGRVRHEKSVPYTQWIAGVLNMMP---RWYIG---
Mflv_2004|M.gilvum_PYR-GCK GLTDPGDRIRAIHARTEQVRREKSLPYTQAIAGVLNLVP---RWYIG---
MSMEG_3933|M.smegmatis_MC2_155 GEVDPMRRIREIHARTMAARGEKALAYTQLIAKALNVMP---RGYVG---
MAB_3551c|M.abscessus_ATCC_199 GEGNTVVRLSQIAHATESHSAAFSLVDVPNMAALSGFVPPTLHALAARVA
* :. *: : :: :* :*
Mb2509c|M.bovis_AF2122/97 GSVIG--SDVQASNVPVYPGDTYLAGAKILRQYGIGPLP-GVAMMVVLIS
Rv2484c|M.tuberculosis_H37Rv GSVIG--SDVQASNVPVYPGDTYLAGAKILRQYGIGPLP-GVAMMVVLIS
MAV_1686|M.avium_104 GSVIG--SDVQASNVPVFPGDTYIAGAKVLRQYGIGPLP-GVAMMVVLIS
MLBr_01244|M.leprae_Br4923 DSVAS--SDVNASNIPAYPGDTYFAGAKILRQYGIGPRP-GVAMMAVLMS
TH_1039|M.thermoresistible__bu GTVVN--SDVQASNVPVILEDTYIAGAKVLRQYGLGPLP-GVAMMVVLVS
MMAR_2649|M.marinum_M SVLRH--VDFLTSDVPGVPVPVFLGGAAVRTQYAFGPTI-GAAVNVTLLS
MUL_3125|M.ulcerans_Agy99 SVLRH--VDFLTSDVPGVPLPVFLGGAAVRTQYAFGPTI-GAAVNVTLLS
Mvan_4103|M.vanbaalenii_PYR-1 SMLRN--IDFLCSDVPGIPVPVFLGGAKVLAQYGFGPTI-GSAVNVTLLT
Mflv_2004|M.gilvum_PYR-GCK SILRH--VDFVASDVPGIPVPVSLGGAKVLMQYAFGPTI-GAAVNITLLT
MSMEG_3933|M.smegmatis_MC2_155 SELRH--VDFIASDVPGSPVPLKMGGAPIRSQYAFSPTL-GAAVNTTLLS
MAB_3551c|M.abscessus_ATCC_199 STLPNRLFNLLVTNVPGPQAPMYLGGARLAEIYPVPPLLRNQVLSIGLTS
. : :. :::* :.** : * . * . .: * :
Mb2509c|M.bovis_AF2122/97 RGGWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGDPAPR-----VL
Rv2484c|M.tuberculosis_H37Rv RGGWCTVTVRYDRASVRNDELFAQCLQAGFDEILALAGGPAPR-----VL
MAV_1686|M.avium_104 RGGWCTITVRYDRASVRDEALFAQCLLEGFDEILALAGDGAPR-----AV
MLBr_01244|M.leprae_Br4923 RGGFCTVTVRYDRASVKSEALFARCLLEGFDEVLALAGDPTPH-----AV
TH_1039|M.thermoresistible__bu RSGYFTVTARYDRAAITDARLFAHCLLAGFNEVLALGGDGRAEPASFEVD
MMAR_2649|M.marinum_M YVDSCALGINVDTGAIPDYDVFYSALVAGFDEVLALAV------------
MUL_3125|M.ulcerans_Agy99 YVDSCALGINVDTGAIPDYDVFYSALVAGFDEVLALAV------------
Mvan_4103|M.vanbaalenii_PYR-1 YVDVCTLGIDADTGAIPDFEVFFDCLVAGFDEVLALG-------------
Mflv_2004|M.gilvum_PYR-GCK YVDTCALGIDADTGAIPDIDVFCDCLRAGFDEVLAVAAD-----------
MSMEG_3933|M.smegmatis_MC2_155 YVDVCAIGVNIDAGAIPDHDVLRDCLTAGFEETLSVHAAGGGPNPT---T
MAB_3551c|M.abscessus_ATCC_199 YNGTVYYGINADREAMPDADMLPLLITEALDELLEAAQ------------
. * :: . :: : .::* *
Mb2509c|M.bovis_AF2122/97 PASFDTQGAGSVPRSVSGS-
Rv2484c|M.tuberculosis_H37Rv PASFDTQGAGSVPRSVSGS-
MAV_1686|M.avium_104 PASFTESAVS--ARSASGS-
MLBr_01244|M.leprae_Br4923 PASFAARSSGSPAGWLSSS-
TH_1039|M.thermoresistible__bu PARLEALMSNAVVPSESAMR
MMAR_2649|M.marinum_M --------------------
MUL_3125|M.ulcerans_Agy99 --------------------
Mvan_4103|M.vanbaalenii_PYR-1 --------------------
Mflv_2004|M.gilvum_PYR-GCK --------------------
MSMEG_3933|M.smegmatis_MC2_155 GGARPRRPHGAPRRPRRG--
MAB_3551c|M.abscessus_ATCC_199 --------------------