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TAVAGTPHSAVQEASALSDESLRDLFAYPDGLQRPWLRANFIASIDGAVTLEGSGRRLGTDTDRRVFARL REVADVVLVGAATATAKPYVDIQMSEDARVWRMSHGLAPELPVAVVSSRGVVPPHLLNNATVPPVVLMSA GASAAARRAVDQSGARVKEFDGRLVTSAAIRDALGGLGLHRVLVEGGPTLFSQLVSDNEIDELCLTTSPK MVAGPARRIVDSASHVEISMERRGILVGGDGTVIVRWART*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4013 | - | - | 100% (251) | deaminase-reductase domain-containing protein |
| M. vanbaalenii PYR-1 | Mvan_2490 | - | 1e-34 | 36.00% (250) | hypothetical protein Mvan_2490 |
| M. vanbaalenii PYR-1 | Mvan_4752 | - | 1e-22 | 33.64% (220) | hypothetical protein Mvan_4752 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2690 | ribD | 4e-30 | 33.07% (251) | hypothetical protein Mb2690 |
| M. gilvum PYR-GCK | Mflv_3913 | - | 6e-35 | 35.04% (254) | hypothetical protein Mflv_3913 |
| M. tuberculosis H37Rv | Rv2671 | ribD | 4e-30 | 33.07% (251) | hypothetical protein Rv2671 |
| M. leprae Br4923 | MLBr_01340 | - | 5e-27 | 30.80% (250) | hypothetical protein MLBr_01340 |
| M. abscessus ATCC 19977 | MAB_2976 | - | 2e-31 | 36.84% (247) | hypothetical protein MAB_2976 |
| M. marinum M | MMAR_2045 | ribD | 4e-34 | 35.95% (242) | bifunctional enzyme riboflavin biosynthesis protein RibD |
| M. avium 104 | MAV_3563 | - | 8e-34 | 34.92% (252) | hypothetical protein MAV_3563 |
| M. smegmatis MC2 155 | MSMEG_2787 | - | 6e-31 | 35.42% (240) | hypothetical protein MSMEG_2787 |
| M. thermoresistible (build 8) | TH_1514 | ribD | 3e-13 | 40.00% (100) | POSSIBLE BIFUNCTIONAL ENZYME RIBOFLAVIN BIOSYNTHESIS PROTEIN |
| M. ulcerans Agy99 | MUL_3305 | ribD | 1e-32 | 35.02% (237) | hypothetical protein MUL_3305 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2690|M.bovis_AF2122/97 MPD-------SGQLG-AADTPLRLLSSVHYLTDGELPQ-LYDYPDD--GT
Rv2671|M.tuberculosis_H37Rv MPD-------SGQLG-AADTPLRLLSSVHYLTDGELPQ-LYDYPDD--GT
MLBr_01340|M.leprae_Br4923 MSDFETGPAASTTAGRAAQTPLLMLTSGRYLDDDELSQ-LYGYPSERAGV
MAV_3563|M.avium_104 MAL--------------PETPLSLLGSVREVDDGELPG-LYDYPDRHAGT
MMAR_2045|M.marinum_M MPD--------PTSGRSADAQLTLLGTDRQLTDEDLPE-FYGYPAKLSGT
MUL_3305|M.ulcerans_Agy99 MPD--------PTSGRSADAQLTLLGTDRQLTDEDLPE-FYGYPAKLSST
MSMEG_2787|M.smegmatis_MC2_155 MSD---------DTAPARFTELTAGGRTVGSGDDELTTRFYAYPDDLRKC
TH_1514|M.thermoresistible__bu --------------------------------------------------
Mflv_3913|M.gilvum_PYR-GCK MSG---------SGDGTHFTLL---GRTDAVGVPDLAA-HYPYPDGLDSC
MAB_2976|M.abscessus_ATCC_1997 MADSDD----EQAIRGPAGTQLTQLTTGAPVDSGELID-LYDFPKN-DKI
Mvan_4013|M.vanbaalenii_PYR-1 -------------MTAVAGTPHSAVQEASALSDESLRD-LFAYPDGLQRP
Mb2690|M.bovis_AF2122/97 WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVR
Rv2671|M.tuberculosis_H37Rv WLRANFISSLDGGATVDGTSGAMAGPGDRFVFNLLRELADVIVVGVGTVR
MLBr_01340|M.leprae_Br4923 WIRANFITSIDGGATADGRTGAMAGPGDRFVFNMLRELADVIVVGAGTVR
MAV_3563|M.avium_104 WVRANFIASVDGGATADGSSGAMGGPGDRFVFNLLRELADVIVVGAGTVR
MMAR_2045|M.marinum_M WLRANFITSLDGGATVGGTSGGLAGPGDRAVFVLLRELADVILVGAGTVR
MUL_3305|M.ulcerans_Agy99 WLRANFITSLDGGATVGGTSGGLAGPGDRAVFVLLRELADVILVGAGTVR
MSMEG_2787|M.smegmatis_MC2_155 RVRANMIVSLDGAATQDGKSGGLGGAGDRAVFNLMRETADVILMGASTVR
TH_1514|M.thermoresistible__bu --------------------------------------------------
Mflv_3913|M.gilvum_PYR-GCK WVRANMITSVDGGATSAGKSGGLGGDGDRALFSALRELADVIVVGAQTVR
MAB_2976|M.abscessus_ATCC_1997 YLRANMISSLDGAATVTGLSGGLGGDGDRAVFAAMRANADVILVGSGTVR
Mvan_4013|M.vanbaalenii_PYR-1 WLRANFIASIDGAVTLEGSGRRLGTDTDRRVFARLREVADVVLVGAATAT
Mb2690|M.bovis_AF2122/97 IEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMA
Rv2671|M.tuberculosis_H37Rv IEGYSGVRMGVVQRQHRQARGQSEVPQLAIVTRSGRLDRDMAVFTRTEMA
MLBr_01340|M.leprae_Br4923 IENYSGAHLPVTKRQQRQARGQSEVPQLAIVTNSGRLDRDMAVFTRTEIA
MAV_3563|M.avium_104 IEGYSGAQLGVAQRQQRQARGQSEVPPLGIVTKSGHLNRDMAVFTRTEVP
MMAR_2045|M.marinum_M IEGYSGAQLGVAERQQRQARGQSEVPQLAIATNSGQLDRDLPVFTRTEVP
MUL_3305|M.ulcerans_Agy99 IEGYSGAQRGVAERQQRQARGQSEVPQLAIATNSGQLDRDLPVFTRTEVP
MSMEG_2787|M.smegmatis_MC2_155 IENYSGVQLSVPQRQARQRRGQAEVPPIAIVTASADLEPDAKIFTRTEVR
TH_1514|M.thermoresistible__bu --------------------------------------------------
Mflv_3913|M.gilvum_PYR-GCK SEDYSGVRLSASARLARQQRGQSEVPPIAVLTRSGRLDRDAKLFTRTDVP
MAB_2976|M.abscessus_ATCC_1997 AERYHGAHLPVGLRQRRQSRGQDEVPTIAVVTASGAVDPSTPLFNESEVA
Mvan_4013|M.vanbaalenii_PYR-1 AKPYVDIQMSEDARVWRMSHGLAPELPVAVVSSRGVVPP--HLLNNATVP
Mb2690|M.bovis_AF2122/97 PLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRR
Rv2671|M.tuberculosis_H37Rv PLVLTTTAVADDTRQRLAGLAEVIACSGDDPGTVDEAVLVSQLAARGLRR
MLBr_01340|M.leprae_Br4923 PLVLTCTETAKKLRTRLADLAYVVSCSGDDPSKVDETVVLATLQTRGLRR
MAV_3563|M.avium_104 PLVLTCAAAADQTRRLLSGLCEVLDCSAGDPERVDEATMLALLGERGMRR
MMAR_2045|M.marinum_M PLVLTAAAAVYDTRRRLTGLAEVVDCSGKDPHRVDEGLLLARLAGRGMRR
MUL_3305|M.ulcerans_Agy99 PLVLTAAAAVYDTRRRLTGLAEVVGCSGKDPHRVDEGLLLARLAGRGMRC
MSMEG_2787|M.smegmatis_MC2_155 PLILTTAHTVSDARRRLGGVAEVLDASGADRTRVDPARALQILAERKLFR
TH_1514|M.thermoresistible__bu ----------------------VLDASGANPDSVDPAVVLRILSERGLWR
Mflv_3913|M.gilvum_PYR-GCK PLILTSTRALDDTRRLLGSVAEVLDASGAQPDSVDPAQALTLLAERGLRR
MAB_2976|M.abscessus_ATCC_1997 PIVVTSASGAPHVASRVPGAQILVSGDG---DTVDLPAALATLHARGLSR
Mvan_4013|M.vanbaalenii_PYR-1 PVVLMSAGASAAARRAVD--QSGARVKEFDGRLVTSAAIRDALGGLGLHR
. * * :
Mb2690|M.bovis_AF2122/97 ILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMR
Rv2671|M.tuberculosis_H37Rv ILTEGGPTLLGTFVERDVLDELCLTIAPYVVGGLARRIVTGPGQVLTRMR
MLBr_01340|M.leprae_Br4923 VLTEGGPMLLGSFIQHGMLDELCLTIAPLIVGGRARRIATGPEQLLTRMR
MAV_3563|M.avium_104 ILTEGGPTLLNSLLERQLLDELCLTIAPYLVGGHARRIATGPGQLLTRMR
MMAR_2045|M.marinum_M ILTEGGPTLFGSLIEQDLLDELCLTIAPVVVGGLPRRIASGPGQLQTRMH
MUL_3305|M.ulcerans_Agy99 ILTEGGPTLFGSLIEQDLLDELCLTIAPVVVGGLPRRIASGPGQLQTRMH
MSMEG_2787|M.smegmatis_MC2_155 VLTEGGPSLLGLLIEHDLLDELCLTIAPVLVGGGAPRIAAGIGQARTRMR
TH_1514|M.thermoresistible__bu VLAEGGPTLLSQMLAAGLLDELCLTVAPVLVGGTGPRIVDGPHRVHQRMR
Mflv_3913|M.gilvum_PYR-GCK VLTEGGPGILGMFTDDDLVDELCVTVAPLLLGGGPGRIVTGDGEVRSGMV
MAB_2976|M.abscessus_ATCC_1997 VLCEGGPALLGTLLSAHLVDELCLTIAPTTIGGAGLRITSGPAEVLTGWR
Mvan_4013|M.vanbaalenii_PYR-1 VLVEGGPTLFSQLVSDNEIDELCLTTSPKMVAGPARRIVDSASHVEISME
:* **** ::. : :****:* :* :.* **. . .
Mb2690|M.bovis_AF2122/97 CAHVLTDDSGYLYTRYVKT-
Rv2671|M.tuberculosis_H37Rv CAHVLTDDSGYLYTRYVKT-
MLBr_01340|M.leprae_Br4923 CAHVLTDDAGYLYTRYVKA-
MAV_3563|M.avium_104 CAHVLTDDAGYLYTRYVRC-
MMAR_2045|M.marinum_M CAHVITDDAGYLYTRYVRA-
MUL_3305|M.ulcerans_Agy99 CAHVITDDAGYLYTRYVRA-
MSMEG_2787|M.smegmatis_MC2_155 VSHLLTDDEGYLYTRYVRG-
TH_1514|M.thermoresistible__bu RTHVLADDDGYLYTRYVKGD
Mflv_3913|M.gilvum_PYR-GCK LGHALTDGDGYLYLRYLRDR
MAB_2976|M.abscessus_ATCC_1997 RVLLLADADGYLFTRYVPA-
Mvan_4013|M.vanbaalenii_PYR-1 RRGILVGGDGTVIVRWART-
:.. * : *: