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SDALVVSTRPVDHVAVVMLNRPETLNALDRGLMDELQVSLQALAGQDDVHVVVLTGAGRGFCSGADFGIL SVLAESDSTFELMKHVSRPVQTLYHLPQLTIAAVNGPAAGAGWGLAMACDIRVAAASARFGATFARMGLG PDYGLSKTLPQAIGRDRALELLTTARIIDADEASAIGAVSAVVDDVLAHTVRLATEVARAPGRTVRSVKR TMRSAAAADFDTAVGVIEARAQAELFNHPDFMDVAAGWVAQVAGKAGPGHRPPVSP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3990 | - | - | 100% (267) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_1625 | - | 2e-37 | 38.65% (251) | enoyl-CoA hydratase/isomerase |
| M. vanbaalenii PYR-1 | Mvan_2741 | - | 9e-33 | 40.50% (242) | enoyl-CoA hydratase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1507 | echA12 | 4e-31 | 39.42% (241) | enoyl-CoA hydratase |
| M. gilvum PYR-GCK | Mflv_4817 | - | 3e-34 | 37.14% (245) | enoyl-CoA hydratase/isomerase |
| M. tuberculosis H37Rv | Rv1472 | echA12 | 2e-30 | 39.00% (241) | enoyl-CoA hydratase |
| M. leprae Br4923 | MLBr_01241 | - | 2e-29 | 40.74% (189) | enoyl-CoA hydratase |
| M. abscessus ATCC 19977 | MAB_2737c | - | 9e-31 | 37.33% (225) | enoyl-CoA hydratase |
| M. marinum M | MMAR_2278 | echA12 | 6e-32 | 39.92% (243) | enoyl-CoA hydratase, EchA12 |
| M. avium 104 | MAV_3307 | - | 2e-32 | 38.01% (271) | enoyl-CoA hydratase |
| M. smegmatis MC2 155 | MSMEG_1739 | - | 8e-37 | 40.95% (232) | enoyl-CoA hydratase/isomerase family protein |
| M. thermoresistible (build 8) | TH_2798 | - | 2e-31 | 38.91% (239) | PUTATIVE Enoyl-CoA hydratase |
| M. ulcerans Agy99 | MUL_4429 | echA12_2 | 2e-31 | 39.17% (217) | enoyl-CoA hydratase, EchA12_2 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1507|M.bovis_AF2122/97 --MPHRCAAQVVAGYRSTVSLVLVEHPRPEIAQITLNRPERMNSMAFDVM
Rv1472|M.tuberculosis_H37Rv --MPHRCAAQVVAGYRSTVSLVLVEHPRPEIAQITLNRPERMNSMAFDVM
MMAR_2278|M.marinum_M ------------------MALVLLEHPRPDIALVTLNRPERMNSMAFDVM
MAV_3307|M.avium_104 ------------------MSLVLVDHPRPGVALITLNRPERMNSMAFDVM
TH_2798|M.thermoresistible__bu ---------------------VLVDHPRPHIALVTLNRPERMNSMAFDVM
MAB_2737c|M.abscessus_ATCC_199 ------------------MSFVLVDRPRPEIALVTLNRPERMNAMAFDVM
MLBr_01241|M.leprae_Br4923 MSQTDASCTIAELPYRSVTDLVVLDFPRPEVALITLNRPGRMNSMALDLM
Mflv_4817|M.gilvum_PYR-GCK -----------------MSSVLEVARPTPEIAVLTLNRPDKLNALSYELV
MSMEG_1739|M.smegmatis_MC2_155 ---------------MSLAQPLDVTRPRPDIAVLTLNRPDKLNALSYELV
MUL_4429|M.ulcerans_Agy99 -----------------------MQTLQHNIACVTLNRPTRLNAIDGSLL
Mvan_3990|M.vanbaalenii_PYR-1 ----------------MSDALVVSTRPVDHVAVVMLNRPETLNALDRGLM
:* : **** :*:: ::
Mb1507|M.bovis_AF2122/97 VPLKEALAQVSYDNSVRVVVLTGAGRGFSSGADHKSAGVVPHVENLTRP-
Rv1472|M.tuberculosis_H37Rv VPLKEALAQVSYDNSVRVVVLTGAGRGFSPGADHKSAGVVPHVENLTRP-
MMAR_2278|M.marinum_M VPLKEVLEEVSYDNSVRVVVLTGAGRGFSSGADHKSAGAVPNVGGLTRP-
MAV_3307|M.avium_104 VPLKEALQKVTYDNAVRVVVLTGAGRGFSSGADHKSAGTVPHVEGLTRP-
TH_2798|M.thermoresistible__bu VPLKAALDEITYDNDVRVVVLTGAGRGFSSGADHKSAGTVPHVDGLTRP-
MAB_2737c|M.abscessus_ATCC_199 LPFKQMLVDISHDNDVRAVVITGAGKGFCSGADQKSAGPIPHIGGLTQP-
MLBr_01241|M.leprae_Br4923 KSLKQVLKRITYDHSVRVVVLTGAGRGFCSGADQKFTAPVPQVEGLTQP-
Mflv_4817|M.gilvum_PYR-GCK EALHAELDALARDNACRAVVLTGAGRGFCSGLDLSAPNPEETGGGTEFP-
MSMEG_1739|M.smegmatis_MC2_155 EALHAALDDIAADNDCRVVVLTGAGRGFCSGLDLSAPNPPEAAGGTEFP-
MUL_4429|M.ulcerans_Agy99 DAMDDALDALSGG-EFRAAILTGAGRGFCAGADLSGTGQPWTKATPTTPP
Mvan_3990|M.vanbaalenii_PYR-1 DELQVSLQALAGQDDVHVVVLTGAGRGFCSGADFGILSVLAESD------
:. * :: :..::****:**..* *
Mb1507|M.bovis_AF2122/97 -TYALRSMELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLALAADIRVAS
Rv1472|M.tuberculosis_H37Rv -TYALRSMELLDDVILMLRRLHQPVIAAVNGPAIGGGLCLALAADIRVAS
MMAR_2278|M.marinum_M -TYALRSMELLDEVILMLRRLHQPVIAAVNGPAIGGGLCLALAADVRVAA
MAV_3307|M.avium_104 -TYALRSMEILDEVILALRRLHQPVIAAVNGPAIGGGLCLALAADIRVAS
TH_2798|M.thermoresistible__bu -SYGLRSMEVLDDVILTLRKLHQPVIAAVNGAAIGGGLCLALAADIRIAS
MAB_2737c|M.abscessus_ATCC_199 -TIALRSMELLDEVILTLRRMHQPVIAAINGAAIGGGLCLALACDVRVAS
MLBr_01241|M.leprae_Br4923 -VRALRAMELLEEVILALRRLHQPVIAAINGPAIGGGLCLALAADVRVAS
Mflv_4817|M.gilvum_PYR-GCK -RSGMRWQERIADLTAKIHRLRQPVIAAVQGVAYGGGLGIAAACDIRVAA
MSMEG_1739|M.smegmatis_MC2_155 -RSGMRWQERIANLTAKLHRLRQPVIAAVNGPAYGGGFALAAASDIRLAA
MUL_4429|M.ulcerans_Agy99 FKATYDAQVRLADQLTRLYELPIPVIAAVNGVAVGGGLAFALHCDIRIAA
Mvan_3990|M.vanbaalenii_PYR-1 --STFELMKHVSRPVQTLYHLPQLTIAAVNGPAAGAGWGLAMACDIRVAA
: : .: .***::* * *.* :* .*:*:*:
Mb1507|M.bovis_AF2122/97 SSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTGRDVSAEEAE
Rv1472|M.tuberculosis_H37Rv SSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTGRDVSAEEAE
MMAR_2278|M.marinum_M ASAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTGRDVTAEEAE
MAV_3307|M.avium_104 TSAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTGRDVTAEEAE
TH_2798|M.thermoresistible__bu TEAYFRAAGINNGLTASELGLSYLLPRAIGSSRAFEIMLTGRDVDAEEAE
MAB_2737c|M.abscessus_ATCC_199 QDAYFRAAGINNGLTASELGLSYLLPRAIGTSRASDIMLTGRDVDADEAE
MLBr_01241|M.leprae_Br4923 TRAYFRAAGINNGLSASELGLSYLLPRAVGSSRAFEIMLSGRDVGAEEAE
Mflv_4817|M.gilvum_PYR-GCK PTARFCTQFIKLGLGGCDIGVSYTLPRIVGAGVAFDMILTARTVAADEAL
MSMEG_1739|M.smegmatis_MC2_155 ESARFCTQFIKLGIGGCDIGVSYTLPRIIGAGPAFDLILTARAVDATEAL
MUL_4429|M.ulcerans_Agy99 EDARFGSVFIKAGFSSMDMGTSYLLPRIVGAGVARELMLTGRIIDAVEAY
Mvan_3990|M.vanbaalenii_PYR-1 ASARFGATFARMGLGP-DYGLSKTLPQAIGRDRALELLTTARIIDADEAS
* * : . *: : * * **: :* . * ::: :.* : * **
Mb1507|M.bovis_AF2122/97 RIGLVSRQVPDEQLLDACYAIAARMAGFSRPGIELTKRTLWSGLDAASLE
Rv1472|M.tuberculosis_H37Rv RIGLVSRQVPDEQLLDACYAIAARMAGFSRPGIELTKRTLWSGLDAASLE
MMAR_2278|M.marinum_M RIGLVSCRVPDGQLLDTCYAIAARMAAFSRPGIELTKRTLWSGLDAASLE
MAV_3307|M.avium_104 RIGLVSCQVPEEQLLDTCYAIAARIAAFSRPGIELTKRTLWSGLDAGSLE
TH_2798|M.thermoresistible__bu RIGLVSRRVPPAELLDTCYELADRIAGFSRPGTELTKRTLWSGLDAGSLE
MAB_2737c|M.abscessus_ATCC_199 RIGLVSRKVASESLLEECYAIGERIAGFSRPGIELTKRTIWSGLDAASLE
MLBr_01241|M.leprae_Br4923 QIGLVSYRVSDDRLLDTCYSIAARMATFSRSGTELTKRALWGGLDAASLD
Mflv_4817|M.gilvum_PYR-GCK RLGLVSR--VSDTPVDEALAIAETLCNYGKFGVESTKQVLWANLVASSLE
MSMEG_1739|M.smegmatis_MC2_155 RLGLVSR--VCADVTAEAMDIAETLCGYGKFGVESTKQVLWANLDAGCLE
MUL_4429|M.ulcerans_Agy99 RIRLVHEVVVADELLTAAQKLAGSIAENNAYGVWQTKIGLNAAPDAPSLR
Mvan_3990|M.vanbaalenii_PYR-1 AIGAVSA--VVDDVLAHTVRLATEVARAPGRTVRSVKRTMRSAAAADFDT
: * :. :. .* : . *
Mb1507|M.bovis_AF2122/97 AHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVFTDDT-------
Rv1472|M.tuberculosis_H37Rv AHMQAEGLGQLFVRLLTANFEEAVAARAEQRAPVFTDDT-------
MMAR_2278|M.marinum_M GHMQAEGLGQLFVRLLTANFEEAVAARAEKRPAVFTDDK-------
MAV_3307|M.avium_104 GHMQAEGLGQLFVRLLTANFEEAVAARAERRPPVFTDDK-------
TH_2798|M.thermoresistible__bu SHMHAEGLGQLYIRLLTHNFEEAVAARKEKRAPRFPDDKI------
MAB_2737c|M.abscessus_ATCC_199 SHMHQEGLGQLYVRLLTDNFEEATAARKEKRPAEFRDKR-------
MLBr_01241|M.leprae_Br4923 KHMQSESLAQLFIALHTSNFEEAAAPCTEKRPTVLVDARGCATSPG
Mflv_4817|M.gilvum_PYR-GCK AALHLENRSQILAS--TSGEMRELAAKILRKG--------------
MSMEG_1739|M.smegmatis_MC2_155 AALHVENRSQILAS--TEGGVRAFSEEFRRRPR-------------
MUL_4429|M.ulcerans_Agy99 HAKEIENRTEIISG-FTNNPAEAARAHQEKRPPAWDSL--------
Mvan_3990|M.vanbaalenii_PYR-1 AVGVIEARAQAELFNHPDFMDVAAGWVAQVAGKAGPGHRPPVSP--
* : .