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SGKLAAAAAAAACACVALSGCTGVPADERPVVRIVEAAQPSPAIPLGPFLPTGQELATLLATGPNGLLGR PVEGDADVLLRSVADAQVAPAECVSAAYRMQEIVYDTSPVQSVASNTWAGGGFDGPPVSGFFGVVQMTDP GAAQEFFASLTDQWRRCNGQTVSLQSPDHGAGEMSRITGVAFDQRVVSAHVLHASGGTESPTGMRAVGLA GDCIVEVELIDPRAAADGRSAVAVADAILDKIAAVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3879 | - | - | 100% (247) | LppR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2426c | lppR | 1e-15 | 34.24% (184) | lipoprotein LppR |
| M. gilvum PYR-GCK | Mflv_2674 | - | 5e-98 | 74.36% (234) | LppR |
| M. tuberculosis H37Rv | Rv2403c | lppR | 1e-15 | 34.24% (184) | lipoprotein LppR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0806 | - | 7e-09 | 25.55% (227) | lipoprotein LppR |
| M. marinum M | MMAR_3723 | lppR_1 | 3e-15 | 27.02% (248) | lipoprotein, LppR_1 |
| M. avium 104 | MAV_1779 | - | 6e-16 | 28.09% (267) | LppR protein |
| M. smegmatis MC2 155 | MSMEG_4555 | - | 6e-15 | 26.52% (264) | LppR protein |
| M. thermoresistible (build 8) | TH_2458 | - | 1e-48 | 46.46% (254) | PUTATIVE LppR |
| M. ulcerans Agy99 | MUL_3666 | lppR_1 | 8e-16 | 27.02% (248) | lipoprotein, LppR_1 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3723|M.marinum_M MTVGRAGWARAVALLGIGLLGTGCTN-----TVAGVSTHAGQPGANALT-
MUL_3666|M.ulcerans_Agy99 MTVGRAGWAGAVALLGIGLLGTGCTN-----TVAGVSTHAGQPGANALT-
Mb2426c|M.bovis_AF2122/97 ----MTNRWRWVVPLFAVFLAAGCTT-----TTTGKAGLAPNAVPRPLMG
Rv2403c|M.tuberculosis_H37Rv ----MTNRWRWVVPLFAVFLAAGCTT-----TTTGKAGLAPNAVPRPLMG
MAV_1779|M.avium_104 ----MRIFTAATLLTAVAALAAGCGG-----VVSGTAKPAPNLKPRPLSG
MSMEG_4555|M.smegmatis_MC2_155 ----MKTIAKWSVVAASLVLVVGCTR-----IVDGSMQPAADLPPRPLRG
Mvan_3879|M.vanbaalenii_PYR-1 --MSGKLAAAAAAAACACVALSGCTG----VPADERPVVRIVEAAQPSPA
Mflv_2674|M.gilvum_PYR-GCK --------------MCLAVTLSGCAG----APVDDRPVVRIVEAAQPSVA
TH_2458|M.thermoresistible__bu ----MRRFGATVAVAAVGVCLAGCTVTADPQAAESPPAVRIDPAVVPSES
MAB_0806|M.abscessus_ATCC_1997 ---MWLRMALWQALLVVVAMLVGCSE-----LVNGRALKPAPPPDPPER-
** . .
MMAR_3723|M.marinum_M --PEQVLPDGEEVKAAVGNDLPPHS---PPMVGDIGVLPNGIRDNSAATP
MUL_3666|M.ulcerans_Agy99 --PEQVLPDGEEVKAAVGNDLPPHS---PPMVGDIGVLPNGIRDNSAAAP
Mb2426c|M.bovis_AF2122/97 SLIQRVPLDGAALSTLLNQPFQALPP-FPPVFGGSDSLGD---SDVSARP
Rv2403c|M.tuberculosis_H37Rv SLIQRVPLDGAALSTLLNQPFQALPP-FPPVFGGSDSLGD---SDVSARP
MAV_1779|M.avium_104 ATVQQVLLDGPTLSRMLNQPFVARD---PAQVGGPEKLYR---GGRSASQ
MSMEG_4555|M.smegmatis_MC2_155 ADIARVLPGVDELSEILDQRMVEDIGGRRDVSGGVEDMPDGLATESDATP
Mvan_3879|M.vanbaalenii_PYR-1 IPLGPFLPTGQELATLLATGPNGLLG--RPVEGDADVLLRS-VADAQVAP
Mflv_2674|M.gilvum_PYR-GCK IPLGPFLPTAAELSATLGTGPNALMA--PPVEGDSDVLLSG-VADAHATP
TH_2458|M.thermoresistible__bu RPLAPILPTAEELSDLLGT--AGFTG--PLVDGDADALLAG-ITDAAASP
MAB_0806|M.abscessus_ATCC_1997 -PITRVLPDQAELSRVLRSPMQARYG---GRPGGVQMLPDG---MAGASL
. : : *. : .
MMAR_3723|M.marinum_M IECLGAIAPAMRISYEVAPVRAAALQDYWNYD----SGVVASSATVAAIK
MUL_3666|M.ulcerans_Agy99 IECLGAIAPAMRISYEVAPVRAAALQDYWNYD----SGVVASSATVAAIK
Mb2426c|M.bovis_AF2122/97 ADCVGVGYLTQRNVYRSVEVKSVARVSWRHDG----SSVKVDDLDEGVVA
Rv2403c|M.tuberculosis_H37Rv ADCVGVGYLTQRNVYRSVEVKSVARVSWRHDG----SSVKVDDVDEGVVA
MAV_1779|M.avium_104 SGCLGVTAMLQKSVYPAADVRDVAAESWWNNG----ELAQVITVMEGVVT
MSMEG_4555|M.smegmatis_MC2_155 HDCVGTTSAMQRSVYESADVTEVISEGFDGDE----DGGAVLAANVGVVA
Mvan_3879|M.vanbaalenii_PYR-1 AECVSAAYRMQEIVYDTSPVQSVASNTWAGGG----FDGPPVSGFFGVVQ
Mflv_2674|M.gilvum_PYR-GCK AHCVSAAYRLQEIVYDDSPVHSVASSTWAGGA----FDGPPVSGFFGVVQ
TH_2458|M.thermoresistible__bu PECVGPAYRLQKSVYGTGPVRGVASRSWAGGS----GEQPTMSGFFGVVR
MAB_0806|M.abscessus_ATCC_1997 VECIKVHAPVMRHTYEQAPVHAATRITWNTERGHMQFPAPDLRTTFGVIE
*: . * * . : ..:
MMAR_3723|M.marinum_M LASSDDAQRLFASFTQQWRQCEGRTVTMYTHDRSDTELYSKVTEVRTDGP
MUL_3666|M.ulcerans_Agy99 LASSDDAQRLFASFTQQWRQCEGRTVTMYTHDRSDTELYSKVTEVRTDGP
Mb2426c|M.bovis_AF2122/97 LPSAAAADDLFARFSAQWKECDGTTLTVPASAFG---QR-SITDVRVADS
Rv2403c|M.tuberculosis_H37Rv LPSAAAADDLFARFSAQWKECDGTTLTVPASAFG---QR-SITDVRVADS
MAV_1779|M.avium_104 LPSAAQAQALFAQFSRQWQQCNGMTTSEQSGPIS---TTNVISDVRATDT
MSMEG_4555|M.smegmatis_MC2_155 LDSVASANKLFDAFAEQWQDCDGTTVTIVKEPVRGGFFTDHVTDVRVENS
Mvan_3879|M.vanbaalenii_PYR-1 MTDPGAAQEFFASLTDQWRRCNGQTVSLQSPDHGAGEMS-RITGVAFDQR
Mflv_2674|M.gilvum_PYR-GCK MASPAAAQEFFAATTEQWRHCNSQTVALQSPERGVGELS-RITDVTFDER
TH_2458|M.thermoresistible__bu FATPTDAEAFFAAAADTWYRCNGQTLVLD---QRGGGAS-RITGVTVDHA
MAB_0806|M.abscessus_ATCC_1997 LDTSDSARSWYRRLAADWRRCEGKTAVIVRANYT---LRYDIGPISDAGD
: * : : * *:. * : :
MMAR_3723|M.marinum_M ILSATIISWDNHHTPQSP----VERAVGVQGDVLADAKVALRP-HSQP--
MUL_3666|M.ulcerans_Agy99 ILSATIISWDNHHTPQSP----VERAVGVQGDVLADAKVALRP-HSQP--
Mb2426c|M.bovis_AF2122/97 VVAATVSLRRGTHSILAS--VPQARAVGVRGNCVVEVAVTFFG-ITHPSD
Rv2403c|M.tuberculosis_H37Rv VVAATVSLRRGTHSILAS--VPQARAVGVRGNCVVEVAVTFFG-ITHPSD
MAV_1779|M.avium_104 TVAATKTATAVLPNMPALRPTPQGRALGVRSNCLVEVEVVFFG-GRRSSD
MSMEG_4555|M.smegmatis_MC2_155 VVAATVEFGHTLDSLITP----VARALGVRANCLVEVDVAYYS-EPESRQ
Mvan_3879|M.vanbaalenii_PYR-1 VVSAHVLHASGGTESPTG-----MRAVGLAGDCIVEVELID---------
Mflv_2674|M.gilvum_PYR-GCK VVSASVLHTSAGTASPTA-----MRALGLAGDCIVEVELTD---------
TH_2458|M.thermoresistible__bu GEHAVVSAVVMRDTGTAM-----QRALGVARDYVVDIEITDGEITDELTG
MAB_0806|M.abscessus_ATCC_1997 LMTTVLMFSGTGSSRPMP----VQRALAQVSRYLIDVEIMDFA---DLKH
: **:. : : :
MMAR_3723|M.marinum_M ------GTRAIELVKVMLRKVSSTN--
MUL_3666|M.ulcerans_Agy99 ------GTRAIELVKVMLRKVSSTN--
Mb2426c|M.bovis_AF2122/97 QGSADISTSAVDIAHAMMDRISELS--
Rv2403c|M.tuberculosis_H37Rv QGSADISTSAVDIAHAMMDRISELS--
MAV_1779|M.avium_104 PGSADLNTSALDIAHAMMDRVSALG--
MSMEG_4555|M.smegmatis_MC2_155 KGNTDVDAVAIDIAHEMMDEISDLT--
Mvan_3879|M.vanbaalenii_PYR-1 PRAAADGRSAVAVADAILDKIAAVR--
Mflv_2674|M.gilvum_PYR-GCK PRAEGPPRGAVAVADVILDKIAASR--
TH_2458|M.thermoresistible__bu GAAAGDTRGAVAVADLMLRKIG-----
MAB_0806|M.abscessus_ATCC_1997 PAEPGITDKAEAIAQLITDQINAGGDI
* :.. : .: