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TVGRAGWAGAVALLGIGLLGTGCTNTVAGVSTHAGQPGANALTPEQVLPDGEEVKAAVGNDLPPHSPPMV GDIGVLPNGIRDNSAAAPIECLGAIAPAMRISYEVAPVRAAALQDYWNYDSGVVASSATVAAIKLASSDD AQRLFASFTQQWRQCEGRTVTMYTHDRSDTELYSKVTEVRTDGPILSATIISWDNHHTPQSPVERAVGVQ GDVLADAKVALRPHSQPGTRAIELVKVMLRKVSSTN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3666 | lppR_1 | - | 100% (247) | lipoprotein, LppR_1 |
| M. ulcerans Agy99 | MUL_3665 | lppR | 2e-18 | 27.53% (247) | lipoprotein, LppR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2426c | lppR | 5e-13 | 24.90% (253) | lipoprotein LppR |
| M. gilvum PYR-GCK | Mflv_2674 | - | 3e-17 | 28.37% (215) | LppR |
| M. tuberculosis H37Rv | Rv2403c | lppR | 4e-13 | 24.90% (253) | lipoprotein LppR |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0806 | - | 4e-15 | 26.43% (227) | lipoprotein LppR |
| M. marinum M | MMAR_3723 | lppR_1 | 1e-139 | 99.19% (247) | lipoprotein, LppR_1 |
| M. avium 104 | MAV_1779 | - | 1e-18 | 29.37% (252) | LppR protein |
| M. smegmatis MC2 155 | MSMEG_4555 | - | 2e-17 | 26.92% (260) | LppR protein |
| M. thermoresistible (build 8) | TH_2458 | - | 2e-11 | 24.31% (255) | PUTATIVE LppR |
| M. vanbaalenii PYR-1 | Mvan_3879 | - | 1e-15 | 27.02% (248) | LppR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2426c|M.bovis_AF2122/97 ----MTNRWRWVVPLFAVFLAAGCTT-----TTTGKAGLAPNAVPRPLMG
Rv2403c|M.tuberculosis_H37Rv ----MTNRWRWVVPLFAVFLAAGCTT-----TTTGKAGLAPNAVPRPLMG
MAV_1779|M.avium_104 ----MRIFTAATLLTAVAALAAGCGG-----VVSGTAKPAPNLKPRPLSG
MSMEG_4555|M.smegmatis_MC2_155 ----MKTIAKWSVVAASLVLVVGCTR-----IVDGSMQPAADLPPRPLRG
MUL_3666|M.ulcerans_Agy99 MTVGRAGWAGAVALLGIGLLGTGCTN-----TVAGVSTHAGQPGANALT-
MMAR_3723|M.marinum_M MTVGRAGWARAVALLGIGLLGTGCTN-----TVAGVSTHAGQPGANALT-
Mflv_2674|M.gilvum_PYR-GCK --------------MCLAVTLSGCAG----APVDDRPVVRIVEAAQPSVA
Mvan_3879|M.vanbaalenii_PYR-1 --MSGKLAAAAAAAACACVALSGCTG----VPADERPVVRIVEAAQPSPA
TH_2458|M.thermoresistible__bu ----MRRFGATVAVAAVGVCLAGCTVTADPQAAESPPAVRIDPAVVPSES
MAB_0806|M.abscessus_ATCC_1997 ---MWLRMALWQALLVVVAMLVGCSE-----LVNGRALKPAPPPDPPER-
** . .
Mb2426c|M.bovis_AF2122/97 SLIQRVPLDGAALSTLLNQPFQALPP-FPPVFGGSDSLGD---SDVSARP
Rv2403c|M.tuberculosis_H37Rv SLIQRVPLDGAALSTLLNQPFQALPP-FPPVFGGSDSLGD---SDVSARP
MAV_1779|M.avium_104 ATVQQVLLDGPTLSRMLNQPFVARD---PAQVGGPEKLYR---GGRSASQ
MSMEG_4555|M.smegmatis_MC2_155 ADIARVLPGVDELSEILDQRMVEDIGGRRDVSGGVEDMPDGLATESDATP
MUL_3666|M.ulcerans_Agy99 --PEQVLPDGEEVKAAVGNDLPPHS---PPMVGDIGVLPNGIRDNSAAAP
MMAR_3723|M.marinum_M --PEQVLPDGEEVKAAVGNDLPPHS---PPMVGDIGVLPNGIRDNSAATP
Mflv_2674|M.gilvum_PYR-GCK IPLGPFLPTAAELSATLGTGPNALMA--PPVEGDSDVLLSG-VADAHATP
Mvan_3879|M.vanbaalenii_PYR-1 IPLGPFLPTGQELATLLATGPNGLLG--RPVEGDADVLLRS-VADAQVAP
TH_2458|M.thermoresistible__bu RPLAPILPTAEELSDLLGT--AGFTG--PLVDGDADALLAG-ITDAAASP
MAB_0806|M.abscessus_ATCC_1997 -PITRVLPDQAELSRVLRSPMQARYG---GRPGGVQMLPDG---MAGASL
. : : *. : .
Mb2426c|M.bovis_AF2122/97 ADCVGVGYLTQRNVYRSVEVKSVARVSWRHDG----SSVKVDDLDEGVVA
Rv2403c|M.tuberculosis_H37Rv ADCVGVGYLTQRNVYRSVEVKSVARVSWRHDG----SSVKVDDVDEGVVA
MAV_1779|M.avium_104 SGCLGVTAMLQKSVYPAADVRDVAAESWWNNG----ELAQVITVMEGVVT
MSMEG_4555|M.smegmatis_MC2_155 HDCVGTTSAMQRSVYESADVTEVISEGFDGDE----DGGAVLAANVGVVA
MUL_3666|M.ulcerans_Agy99 IECLGAIAPAMRISYEVAPVRAAALQDYWNYD----SGVVASSATVAAIK
MMAR_3723|M.marinum_M IECLGAIAPAMRISYEVAPVRAAALQDYWNYD----SGVVASSATVAAIK
Mflv_2674|M.gilvum_PYR-GCK AHCVSAAYRLQEIVYDDSPVHSVASSTWAGGA----FDGPPVSGFFGVVQ
Mvan_3879|M.vanbaalenii_PYR-1 AECVSAAYRMQEIVYDTSPVQSVASNTWAGGG----FDGPPVSGFFGVVQ
TH_2458|M.thermoresistible__bu PECVGPAYRLQKSVYGTGPVRGVASRSWAGGS----GEQPTMSGFFGVVR
MAB_0806|M.abscessus_ATCC_1997 VECIKVHAPVMRHTYEQAPVHAATRITWNTERGHMQFPAPDLRTTFGVIE
*: . * * . : ..:
Mb2426c|M.bovis_AF2122/97 LPSAAAADDLFARFSAQWKECDGTTLTVPASAFG---QR-SITDVRVADS
Rv2403c|M.tuberculosis_H37Rv LPSAAAADDLFARFSAQWKECDGTTLTVPASAFG---QR-SITDVRVADS
MAV_1779|M.avium_104 LPSAAQAQALFAQFSRQWQQCNGMTTSEQSGPIS---TTNVISDVRATDT
MSMEG_4555|M.smegmatis_MC2_155 LDSVASANKLFDAFAEQWQDCDGTTVTIVKEPVRGGFFTDHVTDVRVENS
MUL_3666|M.ulcerans_Agy99 LASSDDAQRLFASFTQQWRQCEGRTVTMYTHDRSDTELYSKVTEVRTDGP
MMAR_3723|M.marinum_M LASSDDAQRLFASFTQQWRQCEGRTVTMYTHDRSDTELYSKVTEVRTDGP
Mflv_2674|M.gilvum_PYR-GCK MASPAAAQEFFAATTEQWRHCNSQTVALQSPERGVGELS-RITDVTFDER
Mvan_3879|M.vanbaalenii_PYR-1 MTDPGAAQEFFASLTDQWRRCNGQTVSLQSPDHGAGEMS-RITGVAFDQR
TH_2458|M.thermoresistible__bu FATPTDAEAFFAAAADTWYRCNGQTLVLD---QRGGGAS-RITGVTVDHA
MAB_0806|M.abscessus_ATCC_1997 LDTSDSARSWYRRLAADWRRCEGKTAVIVRANYT---LRYDIGPISDAGD
: * : : * *:. * : :
Mb2426c|M.bovis_AF2122/97 VVAATVSLRRGTHSILAS--VPQARAVGVRGNCVVEVAVTFFG-ITHPSD
Rv2403c|M.tuberculosis_H37Rv VVAATVSLRRGTHSILAS--VPQARAVGVRGNCVVEVAVTFFG-ITHPSD
MAV_1779|M.avium_104 TVAATKTATAVLPNMPALRPTPQGRALGVRSNCLVEVEVVFFG-GRRSSD
MSMEG_4555|M.smegmatis_MC2_155 VVAATVEFGHTLDSLITP----VARALGVRANCLVEVDVAYYS-EPESRQ
MUL_3666|M.ulcerans_Agy99 ILSATIISWDNHHTPQSP----VERAVGVQGDVLADAKVALRP-HSQP--
MMAR_3723|M.marinum_M ILSATIISWDNHHTPQSP----VERAVGVQGDVLADAKVALRP-HSQP--
Mflv_2674|M.gilvum_PYR-GCK VVSASVLHTSAGTASPTA-----MRALGLAGDCIVEVELTD---------
Mvan_3879|M.vanbaalenii_PYR-1 VVSAHVLHASGGTESPTG-----MRAVGLAGDCIVEVELID---------
TH_2458|M.thermoresistible__bu GEHAVVSAVVMRDTGTAM-----QRALGVARDYVVDIEITDGEITDELTG
MAB_0806|M.abscessus_ATCC_1997 LMTTVLMFSGTGSSRPMP----VQRALAQVSRYLIDVEIMDFA---DLKH
: **:. : : :
Mb2426c|M.bovis_AF2122/97 QGSADISTSAVDIAHAMMDRISELS--
Rv2403c|M.tuberculosis_H37Rv QGSADISTSAVDIAHAMMDRISELS--
MAV_1779|M.avium_104 PGSADLNTSALDIAHAMMDRVSALG--
MSMEG_4555|M.smegmatis_MC2_155 KGNTDVDAVAIDIAHEMMDEISDLT--
MUL_3666|M.ulcerans_Agy99 ------GTRAIELVKVMLRKVSSTN--
MMAR_3723|M.marinum_M ------GTRAIELVKVMLRKVSSTN--
Mflv_2674|M.gilvum_PYR-GCK PRAEGPPRGAVAVADVILDKIAASR--
Mvan_3879|M.vanbaalenii_PYR-1 PRAAADGRSAVAVADAILDKIAAVR--
TH_2458|M.thermoresistible__bu GAAAGDTRGAVAVADLMLRKIG-----
MAB_0806|M.abscessus_ATCC_1997 PAEPGITDKAEAIAQLITDQINAGGDI
* :.. : .: